CO5720997A2 - Proceso para la fabricacion de 2, 3-dicloropiridina - Google Patents

Proceso para la fabricacion de 2, 3-dicloropiridina

Info

Publication number
CO5720997A2
CO5720997A2 CO06082639A CO06082639A CO5720997A2 CO 5720997 A2 CO5720997 A2 CO 5720997A2 CO 06082639 A CO06082639 A CO 06082639A CO 06082639 A CO06082639 A CO 06082639A CO 5720997 A2 CO5720997 A2 CO 5720997A2
Authority
CO
Colombia
Prior art keywords
amino
chloropyridine
salt
hydrochloric acid
dichloropyridine
Prior art date
Application number
CO06082639A
Other languages
English (en)
Inventor
Rafael Shapiro
Original Assignee
E I Dupont De Nemours Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E I Dupont De Nemours Company filed Critical E I Dupont De Nemours Company
Publication of CO5720997A2 publication Critical patent/CO5720997A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Output Control And Ontrol Of Special Type Engine (AREA)

Abstract

1.- Un método para preparar 2,3-dicloropiridina 1, que comprende las etapas de:(1) poner en contracto un 3-amino-2-cloropiridina 2 o una solucion que comprende 3-amino-2-cloropiridina 2 con acido clorhidrico para formar una sal de 3-amino-2-cloropiridina acido clorhidrico;(2) poner en contacto la sal de 3-amino-2-cloropiridina acido clorhidrico con una sal de nitrito para formar una sal de cloruro de diazonio correspondiente; y (3) poner en contacto la sal de cloruro de diazonio correspondiente con acido clorhidrico en la presencia de un catalizados de cobre en donde por lo menos 50% del cobre es (II) en estado de oxidacion, opcionalmente en la presencia de un disolvente organico, para formar 2,3-dicloropiridina.
CO06082639A 2004-01-23 2006-08-22 Proceso para la fabricacion de 2, 3-dicloropiridina CO5720997A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53906804P 2004-01-23 2004-01-23

Publications (1)

Publication Number Publication Date
CO5720997A2 true CO5720997A2 (es) 2007-01-31

Family

ID=34807252

Family Applications (1)

Application Number Title Priority Date Filing Date
CO06082639A CO5720997A2 (es) 2004-01-23 2006-08-22 Proceso para la fabricacion de 2, 3-dicloropiridina

Country Status (18)

Country Link
US (1) US20070161797A1 (es)
EP (1) EP1706381A2 (es)
JP (1) JP2007523065A (es)
KR (1) KR20060130618A (es)
CN (1) CN1910152B (es)
AR (1) AR048217A1 (es)
AU (1) AU2005206576A1 (es)
BR (1) BRPI0506502A (es)
CA (1) CA2553850A1 (es)
CO (1) CO5720997A2 (es)
IL (1) IL176420A (es)
MX (1) MXPA06008208A (es)
MY (1) MY136794A (es)
RU (1) RU2359960C2 (es)
TW (1) TWI336325B (es)
UA (1) UA86604C2 (es)
WO (1) WO2005070888A2 (es)
ZA (1) ZA200605616B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ME00495B (me) 2003-01-28 2011-10-10 Du Pont Cijano antranilamidni insekticidi
WO2007024833A1 (en) * 2005-08-24 2007-03-01 E. I. Du Pont De Nemours And Company Anthranilamides for controlling invertebrate pests
CN100357272C (zh) * 2006-02-06 2007-12-26 南京广通医药化工有限责任公司 一种2,3－二氯吡啶的合成方法
TW200946504A (en) * 2008-03-13 2009-11-16 Du Pont Improved process for the manufacture of 2,3-dichloropyridine
CN101302190B (zh) * 2008-06-30 2011-07-27 河北亚诺化工有限公司 一种制备2,3-二氯吡啶的方法
US8293918B2 (en) * 2008-12-19 2012-10-23 Jubilant Organosys Limited Process for producing dihalopyridines
CN102086174B (zh) * 2011-03-07 2012-10-31 南京广通医药化工有限责任公司 2,3-二氯吡啶的生产方法
CN102153507B (zh) 2011-03-13 2012-11-21 联化科技股份有限公司 一种2，3-二氯吡啶的制备方法
CN102558039A (zh) * 2012-01-13 2012-07-11 江苏中邦制药有限公司 一种2,3-二氯吡啶的制备方法
CN102584693B (zh) * 2012-02-09 2013-08-14 雅本化学股份有限公司 一种高纯度2-氯-3-氨基吡啶盐酸盐的制备方法
CN104662003A (zh) 2012-06-01 2015-05-27 弗特鲁斯专业公司 用于制备二卤吡啶的方法
CN103145609B (zh) * 2013-03-05 2015-08-05 衢州恒顺化工有限公司 一种2,3-二氯吡啶的制备方法
CN103193703B (zh) * 2013-04-26 2014-10-15 山东天信化工有限公司 一种2，3-二氯吡啶的提纯方法
EP2816031A1 (de) 2013-06-18 2014-12-24 Saltigo GmbH Verfahren zur Herstellung von 2,3-Dichlorpyridin
CN103420903A (zh) * 2013-09-03 2013-12-04 天津安锦科技发展有限公司 一种合成2,4-二氯-5-溴吡啶的方法
CN103570609B (zh) * 2013-10-28 2015-11-18 南通天泽化工有限公司 一种2,3-二氯吡啶的制备方法
CN104926715A (zh) * 2015-06-03 2015-09-23 安徽绩溪县徽煌化工有限公司 一种2,3-二氯吡啶的制备方法
CN111170937A (zh) * 2020-01-08 2020-05-19 山东泓达生物科技有限公司 一种3-氨基吡啶的制备方法
CN113149896A (zh) * 2021-03-09 2021-07-23 利尔化学股份有限公司 一种3-氨基吡啶的制备方法
CN113582918B (zh) * 2021-07-16 2023-01-17 内蒙古源宏精细化工有限公司 氯化制备2,3-二氯吡啶的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695659B1 (de) * 1967-12-18 1971-12-16 Ruetgerswerke Ag Verfahren zur Herstellung von 2-Chlorpyridinen
US3838136A (en) * 1973-01-16 1974-09-24 Abbott Lab Preparation of 2-chloro-3-aminopyridine
IT1017606B (it) * 1973-06-06 1977-08-10 Basf Ag Processo per la preparazione di amine e di uree sostituit
US4082749A (en) * 1973-06-06 1978-04-04 Basf Aktiengesellschaft Process for the production of amines

Also Published As

Publication number Publication date
US20070161797A1 (en) 2007-07-12
IL176420A (en) 2011-05-31
UA86604C2 (en) 2009-05-12
AR048217A1 (es) 2006-04-12
RU2006130368A (ru) 2008-02-27
CA2553850A1 (en) 2005-08-04
IL176420A0 (en) 2006-10-05
MY136794A (en) 2008-11-28
BRPI0506502A (pt) 2007-02-27
ZA200605616B (en) 2008-05-28
CN1910152A (zh) 2007-02-07
JP2007523065A (ja) 2007-08-16
EP1706381A2 (en) 2006-10-04
TW200533654A (en) 2005-10-16
CN1910152B (zh) 2010-07-21
TWI336325B (en) 2011-01-21
RU2359960C2 (ru) 2009-06-27
AU2005206576A1 (en) 2005-08-04
MXPA06008208A (es) 2006-08-31
WO2005070888A2 (en) 2005-08-04
WO2005070888A3 (en) 2005-10-20
KR20060130618A (ko) 2006-12-19

Similar Documents

Publication Publication Date Title
CO5720997A2 (es) Proceso para la fabricacion de 2, 3-dicloropiridina
UY29118A1 (es) Procedimiento para producir derivados de amina opticamente activos
JP2007523065A5 (es)
DE60324180D1 (de) Behandlung der huntington's krankheit mit epa
JP2008144269A5 (ja) 有機金属化合物からの金属の回収方法
WO2007009062A3 (en) Treatment of leg ulcers using placenta derived collagen biofabric
EA200702549A1 (ru) Способ производства органического соединения
AR070895A1 (es) Proceso para la elaboracion de 2,3-dicloropiridina
AR098798A1 (es) Procedimiento para la diazotización de 2,5-dicloroanilinas
DE502007001868D1 (de) Verfahren zur gekoppelten herstellung von chlor und isocyanaten
RU2014118565A (ru) Способ производства пероксида водорода
HUP0402367A2 (hu) Elektrokatalizátor, különösképpen ródium-szulfid elektrokatalizátor, valamint eljárás annak létrehozására
NO20083157L (no) Organofil leire og framgangsmate for framstilling og anvendelse av samme
CL2007003859A1 (es) Metodo para eliminar arsenico que comprende contactar la solucion con un agente precipitante de tierra rara para precipitar arsenico y obtener solucion parcialmente liberada de arsenico y agente cargado con arsenico,contactar la solucion separada con una segunda porcion de agente precipitante;y aparato para separar arsenico.
EA200701616A1 (ru) Способ получения промежуточных продуктов
ATE384688T1 (de) Katalytische entfernung von gelöstem sauerstoff aus organischen flüssigkeiten
BRPI0519696A2 (pt) composição aquosa, processo para obter metal de materiais contendo metal, e, uso de tensoativos
ITMI20050466A1 (it) Processo di purificazione in acqua di acido tiottico
BR9913720A (pt) Processo de purificação por cristalização ourecristalização de ácidos carboxìlicos
ATE428730T1 (de) Verfahren zur herstellung einer alpha-1- antitrypsinlösung
DE602004007997D1 (de) Verfahren zur Herstellung von Pantoprazol und seinen Salzen
ATE417848T1 (de) Verfahren zur enantioselektiven herstellung von sulfoxidderivaten
ATE443153T1 (de) Verfahren zur herstellung von eptifibatid
ATE439348T1 (de) Verfahren zum herstellen von carboxamiden
JP2003261556A5 (es)

Legal Events

Date Code Title Description
FC Application refused