CO5570711A2 - Metodo para preparar heparina de cultivos de mastocitos - Google Patents

Metodo para preparar heparina de cultivos de mastocitos

Info

Publication number
CO5570711A2
CO5570711A2 CO04036595A CO04036595A CO5570711A2 CO 5570711 A2 CO5570711 A2 CO 5570711A2 CO 04036595 A CO04036595 A CO 04036595A CO 04036595 A CO04036595 A CO 04036595A CO 5570711 A2 CO5570711 A2 CO 5570711A2
Authority
CO
Colombia
Prior art keywords
mast cells
mastocits
heparine
crops
preparing
Prior art date
Application number
CO04036595A
Other languages
English (en)
Inventor
Pierre Cans
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of CO5570711A2 publication Critical patent/CO5570711A2/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

1.- Procedimiento para la producción de heparina, que se caracteriza por comprender el cultivo de líneas de mastocitos de origen porcino y la recuperación de la heparina a partir de los cultivos obtenidos.Procedimiento según la reivindicación 1, caracterizado porque los mencionados mastocitos son líneas de mastocitos de origen porcino.Procedimiento según las reivindicaciones 1 ó 2, caracterizado porque los mencionados mastocitos provienen de médula ósea de feto de cerdo o de hígado fetal de cerdo.Procedimiento según la reivindicaciones 1 a 3, caracterizado porque los mencionados mastocitos son mastocitos aireados.
CO04036595A 2001-10-22 2004-04-21 Metodo para preparar heparina de cultivos de mastocitos CO5570711A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0113606A FR2831186B1 (fr) 2001-10-22 2001-10-22 Production d'heparine a partir de cultures de mastocytes

Publications (1)

Publication Number Publication Date
CO5570711A2 true CO5570711A2 (es) 2005-10-31

Family

ID=8868558

Family Applications (1)

Application Number Title Priority Date Filing Date
CO04036595A CO5570711A2 (es) 2001-10-22 2004-04-21 Metodo para preparar heparina de cultivos de mastocitos

Country Status (18)

Country Link
US (1) US20050042733A1 (es)
EP (1) EP1438415A2 (es)
JP (1) JP2005506092A (es)
KR (1) KR20040071127A (es)
CN (1) CN1575341A (es)
AR (1) AR036915A1 (es)
BR (1) BR0213478A (es)
CA (1) CA2462714A1 (es)
CO (1) CO5570711A2 (es)
FR (1) FR2831186B1 (es)
HU (1) HUP0401794A2 (es)
IL (1) IL161066A0 (es)
MX (1) MXPA04003740A (es)
NO (1) NO20041633L (es)
NZ (1) NZ532414A (es)
PL (1) PL368599A1 (es)
WO (1) WO2003035886A2 (es)
ZA (1) ZA200402304B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2853663B1 (fr) * 2003-04-14 2007-08-31 Aventis Pharma Sa Procede d'obtention de lignees de mastocytes a partir de tissus de porcs et procede de production de molecules de type heparine
FR2876386B1 (fr) * 2004-10-12 2007-04-06 Aventis Pharma Sa Lignees de mastocytes porcins produisant des molecules de type heparine
KR100688553B1 (ko) * 2005-06-22 2007-03-02 삼성전자주식회사 코어 사이즈를 감소시킨 반도체 메모리 장치
KR101447123B1 (ko) * 2014-02-27 2014-10-06 박상협 헤파린의 추출 방법
KR102104367B1 (ko) 2019-09-02 2020-04-24 팜앤바이오 주식회사 헤파린나트륨의 제조장치 및 제조방법
CN111979193A (zh) * 2019-09-27 2020-11-24 云南洛宇生物科技有限公司 大鼠骨髓源肥大细胞培养方法
CN110592165B (zh) * 2019-10-18 2021-04-27 福州大学 燕窝中硫酸乙酰肝素/肝素的提取方法与结构解析

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3016331A (en) * 1960-01-28 1962-01-09 Ormonoterapia Richter Spa Purification of heparin
AU5810690A (en) * 1989-05-19 1990-12-18 University Of Alabama, The Heparin-producing murine mastocytoma cell lines
DE69405251T2 (de) * 1993-12-10 1998-02-05 Genentech Inc Methoden zur diagnose von allergie und prüfung anti-allergischer therapeutika
FI974321A0 (fi) * 1997-11-25 1997-11-25 Jenny Ja Antti Wihurin Rahasto Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa
US6596705B1 (en) * 1998-02-09 2003-07-22 The Regents Of The University Of California Inhibition of L-selectin and P-selection mediated binding using heparin

Also Published As

Publication number Publication date
HUP0401794A2 (hu) 2004-11-29
CN1575341A (zh) 2005-02-02
ZA200402304B (en) 2004-10-07
AR036915A1 (es) 2004-10-13
NZ532414A (en) 2006-12-22
PL368599A1 (en) 2005-04-04
JP2005506092A (ja) 2005-03-03
KR20040071127A (ko) 2004-08-11
MXPA04003740A (es) 2005-06-20
WO2003035886A2 (fr) 2003-05-01
BR0213478A (pt) 2004-11-03
US20050042733A1 (en) 2005-02-24
NO20041633L (no) 2004-04-21
EP1438415A2 (fr) 2004-07-21
IL161066A0 (en) 2004-08-31
CA2462714A1 (fr) 2003-05-01
FR2831186B1 (fr) 2004-06-18
WO2003035886A3 (fr) 2004-02-26
FR2831186A1 (fr) 2003-04-25

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