FI974321A0 - Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa - Google Patents
Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessaInfo
- Publication number
- FI974321A0 FI974321A0 FI974321A FI974321A FI974321A0 FI 974321 A0 FI974321 A0 FI 974321A0 FI 974321 A FI974321 A FI 974321A FI 974321 A FI974321 A FI 974321A FI 974321 A0 FI974321 A0 FI 974321A0
- Authority
- FI
- Finland
- Prior art keywords
- heparin
- glycosaminoglycans
- compounds
- present
- molecules
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0081—Reaction with amino acids, peptides, or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/06—Use of macromolecular materials
- A61L33/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0066—Isolation or extraction of proteoglycans from organs
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H1/00—Macromolecular products derived from proteins
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI974321A FI974321A0 (fi) | 1997-11-25 | 1997-11-25 | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
CA2311670A CA2311670C (en) | 1997-11-25 | 1998-11-25 | Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions |
US09/230,097 US20020016308A1 (en) | 1997-11-25 | 1998-11-25 | Heparin-like compounds, their preparation and use to prevent arterial thrombsis associated with vascular injury and intervetions |
AT98955631T ATE378358T1 (de) | 1997-11-25 | 1998-11-25 | Heparinähnliche verbindungen, ihre herstellung und verwendung zur verhinderung arterieller thrombose, verbunden mit vaskulärer verletzung und eingriffen |
ES98955631T ES2296346T3 (es) | 1997-11-25 | 1998-11-25 | Compuestos similares a la heparina, su preparacion y utilizacion para prevenir la trombosis arterial asociada a lesiones e intervenciones vasculares. |
DE69838732T DE69838732T2 (de) | 1997-11-25 | 1998-11-25 | Heparinähnliche verbindungen, ihre herstellung und verwendung zur verhinderung arterieller thrombose, verbunden mit vaskulärer verletzung und eingriffen |
EP98955631A EP1034189B1 (en) | 1997-11-25 | 1998-11-25 | Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions |
JP2000522138A JP2001524555A (ja) | 1997-11-25 | 1998-11-25 | ヘパリン様化合物、その製造並びに血管傷害および介入による動脈血栓を阻害するための使用 |
AU12401/99A AU764410B2 (en) | 1997-11-25 | 1998-11-25 | Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions |
DK98955631T DK1034189T3 (da) | 1997-11-25 | 1998-11-25 | Heparinlignende forbindelser, fremstilling og anvendelse deraf til forebyggelse af arteriel thrombose associeret med vaskulære beskadigelser og interventioner |
PCT/FI1998/000925 WO1999026983A1 (en) | 1997-11-25 | 1998-11-25 | Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions |
EP07118457A EP1916260A1 (en) | 1997-11-25 | 1998-11-25 | Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions |
US10/418,095 US7314860B2 (en) | 1997-11-25 | 2003-04-18 | Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions |
US11/826,668 US7504113B2 (en) | 1997-11-25 | 2007-07-17 | Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions |
US12/371,195 US8415324B2 (en) | 1997-11-25 | 2009-02-13 | Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions |
JP2010167172A JP2011017003A (ja) | 1997-11-25 | 2010-07-26 | ヘパリン様化合物、その製造並びに血管傷害および介入による動脈血栓を阻害するための使用 |
JP2011000047A JP2011121956A (ja) | 1997-11-25 | 2011-01-04 | ヘパリン様化合物、その製造並びに血管傷害および介入に伴う動脈血栓を阻止するための使用 |
JP2011000046A JP2011121955A (ja) | 1997-11-25 | 2011-01-04 | ヘパリン様化合物、その製造並びに血管傷害および介入に伴う動脈血栓を阻止するための使用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI974321A FI974321A0 (fi) | 1997-11-25 | 1997-11-25 | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
Publications (1)
Publication Number | Publication Date |
---|---|
FI974321A0 true FI974321A0 (fi) | 1997-11-25 |
Family
ID=8550007
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI974321A FI974321A0 (fi) | 1997-11-25 | 1997-11-25 | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
Country Status (11)
Country | Link |
---|---|
US (4) | US20020016308A1 (fi) |
EP (2) | EP1034189B1 (fi) |
JP (4) | JP2001524555A (fi) |
AT (1) | ATE378358T1 (fi) |
AU (1) | AU764410B2 (fi) |
CA (1) | CA2311670C (fi) |
DE (1) | DE69838732T2 (fi) |
DK (1) | DK1034189T3 (fi) |
ES (1) | ES2296346T3 (fi) |
FI (1) | FI974321A0 (fi) |
WO (1) | WO1999026983A1 (fi) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI974321A0 (fi) * | 1997-11-25 | 1997-11-25 | Jenny Ja Antti Wihurin Rahasto | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
SE0000363L (sv) * | 2000-02-04 | 2001-08-05 | Zoucas Kirurgkonsult Ab | Belagd medicinsk anordning |
SE523216C2 (sv) * | 2001-07-27 | 2004-04-06 | Zoucas Kirurgkonsult Ab | Heparinstent |
FR2831186B1 (fr) * | 2001-10-22 | 2004-06-18 | Aventis Pharma Sa | Production d'heparine a partir de cultures de mastocytes |
DE10221055B4 (de) * | 2002-05-10 | 2007-10-25 | Hemoteq Ag | Verbindungen zur hämokompatiblen Beschichtung von Oberflächen, Verfahren zu deren Herstellung und deren Verwendung |
NZ536330A (en) * | 2002-05-09 | 2007-08-31 | Hemoteq Ag | Medical devices such as stents comprising haemocompatible coating, production and use thereof |
FR2853663B1 (fr) * | 2003-04-14 | 2007-08-31 | Aventis Pharma Sa | Procede d'obtention de lignees de mastocytes a partir de tissus de porcs et procede de production de molecules de type heparine |
US9114194B2 (en) | 2006-05-12 | 2015-08-25 | W. L. Gore & Associates, Inc. | Immobilized biologically active entities having high biological activity following mechanical manipulation |
US8496953B2 (en) | 2006-05-12 | 2013-07-30 | W. L. Gore & Associates, Inc. | Immobilized biologically active entities having a high degree of biological activity following sterilization |
US8021677B2 (en) | 2006-05-12 | 2011-09-20 | Gore Enterprise Holdings, Inc. | Immobilized biologically active entities having a high degree of biological activity |
US8986713B2 (en) | 2006-05-12 | 2015-03-24 | W. L. Gore & Associates, Inc. | Medical device capable of being compacted and expanded having anti-thrombin III binding activity |
DE102008032361A1 (de) | 2008-07-10 | 2010-01-21 | Csl Behring Gmbh | Der Einsatz von Faktor VIII und vWF bzw. vWF-enthaltenden Konzentraten zur Therapie der durch Thrombocyten-Inhibitoren induzierte Koagulopathie |
US8591932B2 (en) * | 2009-09-17 | 2013-11-26 | W. L. Gore & Associates, Inc. | Heparin entities and methods of use |
ES2682482T3 (es) | 2011-03-11 | 2018-09-20 | W. L. Gore & Associates, Inc. | Mejoras para las entidades biológicas inmovilizadas |
PL3821897T3 (pl) * | 2011-12-22 | 2022-11-21 | Corline Biomedical Ab | Środek i sposób leczenia naczyń krwionośnych |
ES2657291T3 (es) | 2013-04-22 | 2018-03-02 | Csl Ltd. | Un complejo covalente de factor de von Willebrand y factor VIII asociado por un puente disulfuro |
US20150305892A1 (en) * | 2014-04-25 | 2015-10-29 | Abbott Cardiovascular Systems Inc. | Methods and Devices for Treating a Bodily Lumen with In Situ Generated Structural Support |
GB201415062D0 (en) | 2014-08-26 | 2014-10-08 | Aplagon Oy | Therapeutic |
KR102415502B1 (ko) * | 2015-08-07 | 2022-07-01 | 삼성전자주식회사 | 복수의 사용자를 위한 라이트 필드 렌더링 방법 및 장치 |
CA3035659C (en) * | 2016-09-16 | 2022-09-06 | Glycologix, Llc | Sulfated glycosaminoglycan biomaterials as proteoglycan mimics |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4265827A (en) * | 1971-03-08 | 1981-05-05 | Monsanto Company | Catalytic asymmetric hydrogenation |
SE425372B (sv) * | 1977-07-18 | 1982-09-27 | Ird Biomaterial Ab | Sett att heparinisera en elektriskt laddad yta pa en medecinsk artikel avsedd att komma i kontakt med blod och medel for utforande av settet |
US4350629A (en) * | 1981-07-29 | 1982-09-21 | Massachusetts Institute Of Technology | Procedures for preparing composite materials from collagen and glycosaminoglycan |
NL188622C (nl) | 1981-12-15 | 1992-08-17 | Cordis Europ | Werkwijze ter verbetering van de bloedcompatibiliteit van een materiaaloppervlak door bekleding daarvan met een heparine of heparine-analoga en een eiwit houdende film, alsmede voorwerp, omvattende een oppervlak met verbeterde bloedcompatibiliteit verkregen onder toepassing van een op het oppervlak aangebrachte heparine of heparine-analoga en een eiwit houdende film. |
US4863907A (en) * | 1984-06-29 | 1989-09-05 | Seikagaku Kogyo Co., Ltd. | Crosslinked glycosaminoglycans and their use |
DE3639561A1 (de) * | 1986-11-20 | 1988-06-01 | Baumann Hanno | Verfahren zur herstellung von nicht-thrombogenen substraten |
DK505488D0 (da) | 1987-12-21 | 1988-09-09 | Bar Shalom Daniel | Middel og anvendelse af samme |
US4945086A (en) * | 1988-05-03 | 1990-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Smooth muscle cell growth inhibitor |
US5019393A (en) * | 1988-08-03 | 1991-05-28 | New England Deaconess Hospital Corporation | Biocompatible substance with thromboresistance |
US5041292A (en) * | 1988-08-31 | 1991-08-20 | Theratech, Inc. | Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents |
US5510418A (en) * | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
US5162430A (en) * | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
WO1991015252A1 (en) | 1990-04-10 | 1991-10-17 | Chembiomed, Ltd. | Nonthrombogenic glycosaminoglycan copolymers |
FR2661332B1 (fr) | 1990-04-25 | 1995-06-16 | Michel Jean Pierre | Prothese ligamentaire et son procede de fabrication. |
IT1251183B (it) * | 1991-08-28 | 1995-05-04 | Opocrin Spa | Dermatan solfato ad alto titolo, dotato di elevata attivita' trombolitica, e forme farmaceutiche che lo contengono. |
SE470006B (sv) * | 1991-09-26 | 1993-10-25 | Corline Systems Ab | Nytt konjugat, dess framställning och användning samt substrat preparerat med konjugatet |
AU2865692A (en) * | 1991-10-04 | 1993-05-03 | Virginia Commonwealth University | Von willebrand factor-specific heparin fractions |
US5571166A (en) * | 1992-03-19 | 1996-11-05 | Medtronic, Inc. | Method of making an intraluminal stent |
WO1994029436A1 (en) * | 1993-06-04 | 1994-12-22 | The United States Of America Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of t cells |
US5618298A (en) * | 1993-10-23 | 1997-04-08 | Simon; Michael | Vascular prosthesis made of resorbable material |
US7229755B1 (en) * | 1993-11-17 | 2007-06-12 | Dana Farber Cancer Institute, Inc. | Method for detection of alterations in the DNA mismatch repair pathway |
US5728518A (en) * | 1994-01-12 | 1998-03-17 | The Immune Response Corporation | Antiviral poly-and oligonucleotides |
AU700584C (en) * | 1994-08-12 | 2002-03-28 | Meadox Medicals, Inc. | Vascular graft impregnated with a heparin-containing collagen sealant |
US5643580A (en) * | 1994-10-17 | 1997-07-01 | Surface Genesis, Inc. | Biocompatible coating, medical device using the same and methods |
US5869127A (en) * | 1995-02-22 | 1999-02-09 | Boston Scientific Corporation | Method of providing a substrate with a bio-active/biocompatible coating |
US5702754A (en) * | 1995-02-22 | 1997-12-30 | Meadox Medicals, Inc. | Method of providing a substrate with a hydrophilic coating and substrates, particularly medical devices, provided with such coatings |
JPH09169801A (ja) * | 1995-10-17 | 1997-06-30 | Terumo Corp | ヘパリン複合体およびそれを被覆した医療器具 |
US6491965B1 (en) * | 1995-11-30 | 2002-12-10 | Hamilton Civic Hospitals Research Development, Inc. | Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates |
US6562781B1 (en) | 1995-11-30 | 2003-05-13 | Hamilton Civic Hospitals Research Development Inc. | Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates |
US5876433A (en) * | 1996-05-29 | 1999-03-02 | Ethicon, Inc. | Stent and method of varying amounts of heparin coated thereon to control treatment |
US5865827A (en) * | 1997-06-03 | 1999-02-02 | Bullister; Edward T | Vacuum device for securing human tissue |
FI974321A0 (fi) * | 1997-11-25 | 1997-11-25 | Jenny Ja Antti Wihurin Rahasto | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
-
1997
- 1997-11-25 FI FI974321A patent/FI974321A0/fi not_active Application Discontinuation
-
1998
- 1998-11-25 WO PCT/FI1998/000925 patent/WO1999026983A1/en active IP Right Grant
- 1998-11-25 DE DE69838732T patent/DE69838732T2/de not_active Expired - Lifetime
- 1998-11-25 ES ES98955631T patent/ES2296346T3/es not_active Expired - Lifetime
- 1998-11-25 EP EP98955631A patent/EP1034189B1/en not_active Expired - Lifetime
- 1998-11-25 DK DK98955631T patent/DK1034189T3/da active
- 1998-11-25 JP JP2000522138A patent/JP2001524555A/ja not_active Withdrawn
- 1998-11-25 US US09/230,097 patent/US20020016308A1/en not_active Abandoned
- 1998-11-25 EP EP07118457A patent/EP1916260A1/en not_active Withdrawn
- 1998-11-25 CA CA2311670A patent/CA2311670C/en not_active Expired - Lifetime
- 1998-11-25 AT AT98955631T patent/ATE378358T1/de not_active IP Right Cessation
- 1998-11-25 AU AU12401/99A patent/AU764410B2/en not_active Ceased
-
2003
- 2003-04-18 US US10/418,095 patent/US7314860B2/en not_active Expired - Lifetime
-
2007
- 2007-07-17 US US11/826,668 patent/US7504113B2/en not_active Expired - Fee Related
-
2009
- 2009-02-13 US US12/371,195 patent/US8415324B2/en not_active Expired - Fee Related
-
2010
- 2010-07-26 JP JP2010167172A patent/JP2011017003A/ja active Pending
-
2011
- 2011-01-04 JP JP2011000047A patent/JP2011121956A/ja active Pending
- 2011-01-04 JP JP2011000046A patent/JP2011121955A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20020016308A1 (en) | 2002-02-07 |
US20090202607A1 (en) | 2009-08-13 |
US20080014239A1 (en) | 2008-01-17 |
JP2001524555A (ja) | 2001-12-04 |
JP2011121955A (ja) | 2011-06-23 |
AU1240199A (en) | 1999-06-15 |
EP1034189B1 (en) | 2007-11-14 |
ES2296346T3 (es) | 2008-04-16 |
EP1916260A1 (en) | 2008-04-30 |
DE69838732D1 (de) | 2007-12-27 |
CA2311670A1 (en) | 1999-06-03 |
WO1999026983A1 (en) | 1999-06-03 |
EP1034189A1 (en) | 2000-09-13 |
JP2011017003A (ja) | 2011-01-27 |
US7314860B2 (en) | 2008-01-01 |
DK1034189T3 (da) | 2008-02-25 |
CA2311670C (en) | 2010-02-09 |
US7504113B2 (en) | 2009-03-17 |
DE69838732T2 (de) | 2008-10-30 |
JP2011121956A (ja) | 2011-06-23 |
AU764410B2 (en) | 2003-08-21 |
US8415324B2 (en) | 2013-04-09 |
ATE378358T1 (de) | 2007-11-15 |
US20030212042A1 (en) | 2003-11-13 |
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