CO5271728A1 - Forma de dosificacion de farmaco en capas impulsadas por hidrogel - Google Patents

Forma de dosificacion de farmaco en capas impulsadas por hidrogel

Info

Publication number
CO5271728A1
CO5271728A1 CO00097187A CO00097187A CO5271728A1 CO 5271728 A1 CO5271728 A1 CO 5271728A1 CO 00097187 A CO00097187 A CO 00097187A CO 00097187 A CO00097187 A CO 00097187A CO 5271728 A1 CO5271728 A1 CO 5271728A1
Authority
CO
Colombia
Prior art keywords
dosage form
hour
weight
environment
sertraline
Prior art date
Application number
CO00097187A
Other languages
English (en)
Inventor
William John Curatolo
Fergione Michael Bruce
Michael Christopher Roy
Govind Thombre Avinash
Kenneth Craig Waterman
Elizabeth Appel Leah
Ronald Arthur Beyerinck
Thomas Friesen Dwayne
Danielle Supple
Mark Brian Chidlaw
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CO5271728A1 publication Critical patent/CO5271728A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un forma de dosificación de liberación controlada para sertralina tiene un núcleo que comprende una composición que contienen sertralina y una composición hinchable en agua, en donde la composición hinchable en agua está situada en una región separada dentro del núcleo. Un revestimiento en torno al núcleo es permeable al agua, insoluble en agua, y tiene al menos una abertura de suministro a través del mismo. En una realización, la forma de dosificación libera sertralina hacia el entorno de uso con una velocidad media de 6 a 10% en peso por hora desde la segunda hasta la décima hora después de la introducción en un entorno de uso, y menos de aproximadamente 25% en peso durante las dos primeras horas y al menos 70% en peso al cabo de la décima hora, en donde los porcentajes corresponden a la masa de fármaco liberado desde el comprimido dividida por la masa total de fármaco originalmente presente en el comprimido. En otra realización, la forma de dosificación libera menos de aproximadamente 25% en peso de sertralina hacia el entorno de uso al cabo de la segunda hora después de la introducción de la forma de dosificación en el entorno de uso, y suministra al menos 25% en peso desde la octava hora hasta la vigesimocuarta.<EMI FILE="00097187_1" ID="1" IMF=JPEG >
CO00097187A 1999-12-23 2000-12-21 Forma de dosificacion de farmaco en capas impulsadas por hidrogel CO5271728A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17210899P 1999-12-23 1999-12-23

Publications (1)

Publication Number Publication Date
CO5271728A1 true CO5271728A1 (es) 2003-04-30

Family

ID=22626396

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00097187A CO5271728A1 (es) 1999-12-23 2000-12-21 Forma de dosificacion de farmaco en capas impulsadas por hidrogel

Country Status (15)

Country Link
US (1) US6899896B2 (es)
EP (1) EP1239839A2 (es)
JP (1) JP2003518487A (es)
AR (1) AR027066A1 (es)
AU (1) AU1724301A (es)
BR (1) BR0016707A (es)
CA (1) CA2395231C (es)
CO (1) CO5271728A1 (es)
GT (1) GT200000220A (es)
MX (1) MXPA02006335A (es)
PA (1) PA8508901A1 (es)
PE (1) PE20010983A1 (es)
TN (1) TNSN00251A1 (es)
UY (1) UY26493A1 (es)
WO (1) WO2001047498A2 (es)

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US20040146559A1 (en) * 2002-09-28 2004-07-29 Sowden Harry S. Dosage forms having an inner core and outer shell with different shapes
US20040062804A1 (en) * 2001-09-28 2004-04-01 Der-Yang Lee Modified release dosage forms
DE60320940D1 (de) 2002-02-01 2008-06-26 Pfizer Prod Inc Pharmazeutische zusammensetzungen amorpher dispersionen von wirkstoffen und lipophiler mikrophasenbildender materialien
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WO2006072878A1 (en) * 2005-01-07 2006-07-13 Ranbaxy Laboratories Limited Oral dosage forms of sertraline having controlled particle size and processes for their preparation
US20060233882A1 (en) * 2005-04-15 2006-10-19 Sowden Harry S Osmotic dosage form
US20060239956A1 (en) * 2005-04-26 2006-10-26 Lulu Henson Preparation and use of hydrogels
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US8957114B2 (en) * 2009-12-04 2015-02-17 Sunovion Pharmaceuticals Inc. Formulations, salts and polymorphs of transnorsertraline and uses thereof
US10485770B2 (en) 2009-12-21 2019-11-26 Aptapharma, Inc. Functionally-coated multilayer tablets
WO2016020936A2 (en) * 2014-07-21 2016-02-11 Patel Jayendrakumar Dasharathlal A novel oral gastroretentive pharmaceutical dosage form
JP6455293B2 (ja) * 2015-04-21 2019-01-23 ニプロ株式会社 セルトラリン及び／又はその薬学上許容しうる塩を含む製剤

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Also Published As

Publication number Publication date
MXPA02006335A (es) 2002-12-13
WO2001047498A2 (en) 2001-07-05
PA8508901A1 (es) 2003-12-10
AR027066A1 (es) 2003-03-12
CA2395231C (en) 2006-08-15
JP2003518487A (ja) 2003-06-10
US20010044474A1 (en) 2001-11-22
WO2001047498A3 (en) 2001-11-15
GT200000220A (es) 2002-06-14
UY26493A1 (es) 2001-07-31
CA2395231A1 (en) 2001-07-05
BR0016707A (pt) 2002-09-03
US6899896B2 (en) 2005-05-31
EP1239839A2 (en) 2002-09-18
PE20010983A1 (es) 2001-10-01
TNSN00251A1 (fr) 2002-05-30
AU1724301A (en) 2001-07-09

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