CO5261529A1 - Uso de antagonistas selectivos de receptores de tipo 4(ep4) de la prostaglandina pde2 para el tratamiento de la insuficiencia renal aguda y cronica - Google Patents

Uso de antagonistas selectivos de receptores de tipo 4(ep4) de la prostaglandina pde2 para el tratamiento de la insuficiencia renal aguda y cronica

Info

Publication number
CO5261529A1
CO5261529A1 CO01007013A CO01007013A CO5261529A1 CO 5261529 A1 CO5261529 A1 CO 5261529A1 CO 01007013 A CO01007013 A CO 01007013A CO 01007013 A CO01007013 A CO 01007013A CO 5261529 A1 CO5261529 A1 CO 5261529A1
Authority
CO
Colombia
Prior art keywords
chronic renal
receptors
acute
renal failure
agonist
Prior art date
Application number
CO01007013A
Other languages
English (en)
Inventor
Madhav Paralkar Vishwas
Thompson David Duane
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CO5261529A1 publication Critical patent/CO5261529A1/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Uso de un agonista selectivo de receptores EP4, de unisómero del mismo, de un profármaco de los citados agonista o isómero o de una sal farmacéuticamente aceptable de los citados agonista, isómero o profármaco, para la fabricación de un medicamento para tratar la insuficiencia o la disfunción renal aguda o crónica, o una dolencia causada por ésta, en un mamífero. El uso de acuerdo con la reivindicación 1, en el que la citada dolencia se selecciona del grupo formado por hipertensión, insuficiencia cardíaca congestiva, glomerulonefritis, uremia e insuficiencia renal crónica. El uso de acuerdo con la reivindicación 1, en el que el citado agonista selectivo de receptores EP4 es un compuesto de fórmula I:<EMI FILE="01007013_1" ID="1" IMF=JPEG >un profármaco del mismo o una sal farmacéuticamente aceptable.
CO01007013A 2000-01-31 2001-01-31 Uso de antagonistas selectivos de receptores de tipo 4(ep4) de la prostaglandina pde2 para el tratamiento de la insuficiencia renal aguda y cronica CO5261529A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17896800P 2000-01-31 2000-01-31

Publications (1)

Publication Number Publication Date
CO5261529A1 true CO5261529A1 (es) 2003-03-31

Family

ID=22654657

Family Applications (1)

Application Number Title Priority Date Filing Date
CO01007013A CO5261529A1 (es) 2000-01-31 2001-01-31 Uso de antagonistas selectivos de receptores de tipo 4(ep4) de la prostaglandina pde2 para el tratamiento de la insuficiencia renal aguda y cronica

Country Status (18)

Country Link
US (1) US6610719B2 (es)
EP (1) EP1132086B1 (es)
JP (2) JP3839261B2 (es)
KR (1) KR100419684B1 (es)
AT (1) ATE327751T1 (es)
AU (1) AU774569B2 (es)
CA (1) CA2332687A1 (es)
CO (1) CO5261529A1 (es)
CY (1) CY1105299T1 (es)
DE (1) DE60120007T2 (es)
DK (1) DK1132086T3 (es)
ES (1) ES2263557T3 (es)
HU (1) HUP0100495A3 (es)
IL (1) IL141120A0 (es)
NZ (1) NZ509632A (es)
PE (1) PE20011048A1 (es)
PT (1) PT1132086E (es)
ZA (1) ZA200100827B (es)

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Also Published As

Publication number Publication date
KR20010078209A (ko) 2001-08-20
JP2006182788A (ja) 2006-07-13
PT1132086E (pt) 2006-09-29
EP1132086B1 (en) 2006-05-31
EP1132086A3 (en) 2002-01-09
IL141120A0 (en) 2002-02-10
US6610719B2 (en) 2003-08-26
DE60120007T2 (de) 2006-11-16
ZA200100827B (en) 2002-07-30
AU1672201A (en) 2001-08-02
ATE327751T1 (de) 2006-06-15
NZ509632A (en) 2003-01-31
AU774569B2 (en) 2004-07-01
JP3839261B2 (ja) 2006-11-01
DK1132086T3 (da) 2006-08-28
HU0100495D0 (en) 2001-03-28
DE60120007D1 (de) 2006-07-06
HUP0100495A2 (en) 2002-10-28
CY1105299T1 (el) 2010-03-03
KR100419684B1 (ko) 2004-02-21
JP2001233792A (ja) 2001-08-28
PE20011048A1 (es) 2001-10-19
US20010041729A1 (en) 2001-11-15
CA2332687A1 (en) 2001-07-31
EP1132086A2 (en) 2001-09-12
ES2263557T3 (es) 2006-12-16
HUP0100495A3 (en) 2003-12-29

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