HUP0100495A3 - Use of prostaglandin (pge2)receptor 4 (ep4)selective agonists for producing pharmaceutical compositions suitable for the treatment of acute and chronic renal failure - Google Patents

Use of prostaglandin (pge2)receptor 4 (ep4)selective agonists for producing pharmaceutical compositions suitable for the treatment of acute and chronic renal failure

Info

Publication number
HUP0100495A3
HUP0100495A3 HU0100495A HUP0100495A HUP0100495A3 HU P0100495 A3 HUP0100495 A3 HU P0100495A3 HU 0100495 A HU0100495 A HU 0100495A HU P0100495 A HUP0100495 A HU P0100495A HU P0100495 A3 HUP0100495 A3 HU P0100495A3
Authority
HU
Hungary
Prior art keywords
pge2
prostaglandin
receptor
acute
treatment
Prior art date
Application number
HU0100495A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HU0100495D0 publication Critical patent/HU0100495D0/hu
Publication of HUP0100495A2 publication Critical patent/HUP0100495A2/hu
Publication of HUP0100495A3 publication Critical patent/HUP0100495A3/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0100495A 2000-01-31 2001-01-30 Use of prostaglandin (pge2)receptor 4 (ep4)selective agonists for producing pharmaceutical compositions suitable for the treatment of acute and chronic renal failure HUP0100495A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17896800P 2000-01-31 2000-01-31

Publications (3)

Publication Number Publication Date
HU0100495D0 HU0100495D0 (en) 2001-03-28
HUP0100495A2 HUP0100495A2 (en) 2002-10-28
HUP0100495A3 true HUP0100495A3 (en) 2003-12-29

Family

ID=22654657

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0100495A HUP0100495A3 (en) 2000-01-31 2001-01-30 Use of prostaglandin (pge2)receptor 4 (ep4)selective agonists for producing pharmaceutical compositions suitable for the treatment of acute and chronic renal failure

Country Status (18)

Country Link
US (1) US6610719B2 (hu)
EP (1) EP1132086B1 (hu)
JP (2) JP3839261B2 (hu)
KR (1) KR100419684B1 (hu)
AT (1) ATE327751T1 (hu)
AU (1) AU774569B2 (hu)
CA (1) CA2332687A1 (hu)
CO (1) CO5261529A1 (hu)
CY (1) CY1105299T1 (hu)
DE (1) DE60120007T2 (hu)
DK (1) DK1132086T3 (hu)
ES (1) ES2263557T3 (hu)
HU (1) HUP0100495A3 (hu)
IL (1) IL141120A0 (hu)
NZ (1) NZ509632A (hu)
PE (1) PE20011048A1 (hu)
PT (1) PT1132086E (hu)
ZA (1) ZA200100827B (hu)

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PT1339678E (pt) 2000-11-27 2007-11-30 Pfizer Prod Inc Agonistas selectivos do receptor ep4 no tratamento de osteoporose
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TWI313608B (en) * 2001-07-23 2009-08-21 Ono Pharmaceutical Co Lower bone mass treating agent containing er4 agonist as active ingredient
WO2003035064A1 (en) * 2001-10-23 2003-05-01 Applied Research Systems Ars Holding N.V. Pyrazolidinone compounds as ligands of the prostaglandin ep2 and/or ep4 receptors
US20040254230A1 (en) * 2001-12-03 2004-12-16 Ogidigben Miller J. Method for treating ocular hypertension
JP4547912B2 (ja) * 2002-03-05 2010-09-22 小野薬品工業株式会社 8−アザプロスタグランジン誘導体化合物およびその化合物を有効成分として含有する薬剤
CA2479222A1 (en) * 2002-03-18 2003-09-25 Pfizer Products Inc. Use of selective ep4 receptor agonists for the treatment of liver failure, loss of patency of the ductus arteriosus, glaucoma or ocular hypertension
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
CA2488001C (en) * 2002-06-06 2011-03-22 Merck Frosst Canada & Co. 1,5-distributed pyrrolid-2-one derivatives for use as ep4 receptor agonists in the treatment of eye diseases such as glaucoma
JP4754820B2 (ja) * 2002-06-10 2011-08-24 メルク セローノ ソシエテ アノニム プロスタグランジン作動薬としてのγラクタムおよびその使用
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US7256211B1 (en) 2003-01-21 2007-08-14 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivatives and medical use thereof
GB0302094D0 (en) * 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
US6734206B1 (en) 2003-06-02 2004-05-11 Allergan, Inc. 3-oxa-8-azaprostaglandin analogs as agents for lowering intraocular pressure
US6734201B1 (en) 2003-06-02 2004-05-11 Allergan, Inc. 8-Azaprostaglandin carbonate and thiocarbonate analogs as therapeutic agents
GB0324269D0 (en) * 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
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US7893107B2 (en) * 2005-11-30 2011-02-22 Allergan, Inc. Therapeutic methods using prostaglandin EP4 agonist components
US20070232660A1 (en) * 2006-04-04 2007-10-04 Allergan, Inc. Therapeutic and delivery methods of prostaglandin ep4 agonists
EP2094839B1 (en) 2006-12-08 2020-02-05 University of Rochester Expansion of hematopoietic stem cells
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EP2408444A4 (en) 2009-03-19 2012-09-26 Fate Therapeutics Inc COMPOSITIONS WITH CYCLIC AMP AMPLIFIERS AND / OR EP LIGANDS, AND METHOD FOR THEIR PRODUCTION AND USE
CA2738045C (en) 2010-05-28 2019-02-19 Simon Fraser University Conjugate compounds, methods of making same, and uses thereof
KR101967868B1 (ko) 2010-06-17 2019-08-19 닛토덴코 가부시키가이샤 신장 섬유증 치료 물질
EP3278808A1 (en) 2010-08-12 2018-02-07 Fate Therapeutics, Inc. Improved hematopoietic stem and progenitor cell therapy
JP6052175B2 (ja) 2011-08-02 2016-12-27 小野薬品工業株式会社 左室拡張機能改善剤
EP3269802B1 (en) 2011-09-30 2019-10-23 Bluebird Bio, Inc. Compounds for improved viral transduction
JP6220791B2 (ja) 2011-12-02 2017-10-25 フェイト セラピューティクス,インコーポレイテッド 増強された幹細胞組成物
EP2785350B1 (en) 2011-12-02 2018-05-02 Fate Therapeutics, Inc. Improved methods of treating ischemia
JP6400479B2 (ja) 2012-10-29 2018-10-03 株式会社カルディオ 肺疾患特異的治療剤
US9943545B2 (en) 2013-03-15 2018-04-17 Fate Therapeutics, Inc. Stem cell culture media and methods of enhancing cell survival
WO2014150602A1 (en) 2013-03-15 2014-09-25 Fate Therapeutics, Inc. Cell potency assay for therapeutic potential
US9968716B2 (en) 2013-10-15 2018-05-15 Ono Pharmaceutical Co., Ltd. Drug-eluting stent graft
KR102166110B1 (ko) 2014-01-24 2020-10-16 에이엠-파마 비.브이. 키메라 알칼리성 포스파타제-유사 단백질
CN106459143A (zh) 2014-01-24 2017-02-22 安-法玛公司 碱性磷酸酶的下游处理
US9650414B1 (en) 2014-05-30 2017-05-16 Simon Fraser University Dual-action EP4 agonist—bisphosphonate conjugates and uses thereof
CN112481211B (zh) 2015-01-26 2024-07-05 儿童医院公司 免疫调节性提高的细胞及其使用和生产方法
US10400000B2 (en) 2015-06-12 2019-09-03 Simon Fraser University Amide-linked EP4 agonist-bisphosphonate compounds and uses thereof
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CA3014078A1 (en) 2016-02-12 2017-08-17 Bluebird Bio, Inc. Vcn enhancer compositions and methods of using the same
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Also Published As

Publication number Publication date
KR20010078209A (ko) 2001-08-20
JP2006182788A (ja) 2006-07-13
PT1132086E (pt) 2006-09-29
EP1132086B1 (en) 2006-05-31
EP1132086A3 (en) 2002-01-09
IL141120A0 (en) 2002-02-10
US6610719B2 (en) 2003-08-26
DE60120007T2 (de) 2006-11-16
CO5261529A1 (es) 2003-03-31
ZA200100827B (en) 2002-07-30
AU1672201A (en) 2001-08-02
ATE327751T1 (de) 2006-06-15
NZ509632A (en) 2003-01-31
AU774569B2 (en) 2004-07-01
JP3839261B2 (ja) 2006-11-01
DK1132086T3 (da) 2006-08-28
HU0100495D0 (en) 2001-03-28
DE60120007D1 (de) 2006-07-06
HUP0100495A2 (en) 2002-10-28
CY1105299T1 (el) 2010-03-03
KR100419684B1 (ko) 2004-02-21
JP2001233792A (ja) 2001-08-28
PE20011048A1 (es) 2001-10-19
US20010041729A1 (en) 2001-11-15
CA2332687A1 (en) 2001-07-31
EP1132086A2 (en) 2001-09-12
ES2263557T3 (es) 2006-12-16

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