CO2019012418A2 - Revestimientos superficiales, protectores para celdas de flujo - Google Patents

Revestimientos superficiales, protectores para celdas de flujo

Info

Publication number
CO2019012418A2
CO2019012418A2 CONC2019/0012418A CO2019012418A CO2019012418A2 CO 2019012418 A2 CO2019012418 A2 CO 2019012418A2 CO 2019012418 A CO2019012418 A CO 2019012418A CO 2019012418 A2 CO2019012418 A2 CO 2019012418A2
Authority
CO
Colombia
Prior art keywords
functionalized polymer
coating layer
polymer coating
substrate
exposed surface
Prior art date
Application number
CONC2019/0012418A
Other languages
English (en)
Inventor
Sean M Ramirez
Brian D Mather
Edwin Li
Sojeong Moon
Innsu Daniel Kim
Alexandre Richez
Ludovic Vincent
Hatten Xavier Von
Hai Quang Tran
Maxwell Zimmerley
Julia Morrison
Gianluca Andrea Artioli
Krystal Sly
Hayden Black
Lewis J Kraft
Hong Xie
Wei Wei
Ryan Sanford
Original Assignee
Illumina Inc
Illumina Cambridge Ltd
Illumina Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc, Illumina Cambridge Ltd, Illumina Singapore Pte Ltd filed Critical Illumina Inc
Publication of CO2019012418A2 publication Critical patent/CO2019012418A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)

Abstract

Un ejemplo de un método incluye proporcionar un sustrato con una superficie expuesta que comprende un primer grupo químico, en donde la provisión comprende opcionalmente modificar la superficie expuesta del sustrato para incorporar el primer grupo químico; hacer reaccionar el primer grupo químico con un primer grupo reactivo de una molécula de polímero funcionalizado para formar una capa de revestimiento de polímero funcionalizado unida covalentemente a la superficie expuesta del sustrato; injertar un cebador en la capa de revestimiento de polímero funcionalizado al hacer reaccionar el cebador con un segundo grupo reactivo de la capa de revestimiento de polímero funcionalizado; y formar un revestimiento protector soluble en agua sobre el cebador y la capa de revestimiento de polímero funcionalizado. Ejemplos de celdas de flujo que incorporan ejemplos del revestimiento protector soluble en agua también se describen en la presente.
CONC2019/0012418A 2017-05-11 2019-11-06 Revestimientos superficiales, protectores para celdas de flujo CO2019012418A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762504977P 2017-05-11 2017-05-11
PCT/US2018/030689 WO2018208561A1 (en) 2017-05-11 2018-05-02 Protective surface coatings for flow cells

Publications (1)

Publication Number Publication Date
CO2019012418A2 true CO2019012418A2 (es) 2020-05-15

Family

ID=64096452

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2019/0012418A CO2019012418A2 (es) 2017-05-11 2019-11-06 Revestimientos superficiales, protectores para celdas de flujo

Country Status (23)

Country Link
US (2) US11667969B2 (es)
EP (1) EP3621735A4 (es)
JP (1) JP7304158B2 (es)
KR (1) KR102626963B1 (es)
CN (1) CN109689216B (es)
AU (1) AU2018266308B2 (es)
BR (1) BR112018077164A2 (es)
CA (1) CA3026659C (es)
CL (1) CL2019003184A1 (es)
CO (1) CO2019012418A2 (es)
CR (1) CR20190552A (es)
IL (1) IL264007B2 (es)
MX (1) MX2018015072A (es)
NL (1) NL2019044B1 (es)
NZ (1) NZ748938A (es)
PE (1) PE20200648A1 (es)
PH (1) PH12019502530A1 (es)
RU (1) RU2729688C1 (es)
SA (1) SA518400716B1 (es)
SG (1) SG11201811460TA (es)
TW (1) TW201905208A (es)
WO (1) WO2018208561A1 (es)
ZA (1) ZA201808187B (es)

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TW202043486A (zh) 2019-01-29 2020-12-01 美商伊路米納有限公司 定序套組
CN110055318A (zh) * 2019-05-06 2019-07-26 南京拓远生物科技有限公司 一种基于点击化学的三维dna微阵列表面的制备方法
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Also Published As

Publication number Publication date
US11667969B2 (en) 2023-06-06
ZA201808187B (en) 2024-04-24
CA3026659C (en) 2022-08-02
JP2020519231A (ja) 2020-07-02
SG11201811460TA (en) 2019-01-30
IL264007B2 (en) 2023-07-01
MX2018015072A (es) 2020-01-14
CA3026659A1 (en) 2018-11-15
AU2018266308B2 (en) 2023-05-11
PE20200648A1 (es) 2020-06-11
IL264007A (en) 2019-01-31
SA518400716B1 (ar) 2023-02-12
US20230272469A1 (en) 2023-08-31
US20180327832A1 (en) 2018-11-15
BR112018077164A2 (pt) 2019-04-02
EP3621735A4 (en) 2021-03-24
CN109689216A (zh) 2019-04-26
PH12019502530A1 (en) 2020-06-29
NL2019044B1 (en) 2018-11-15
CR20190552A (es) 2020-01-28
AU2018266308A1 (en) 2019-01-03
WO2018208561A1 (en) 2018-11-15
JP7304158B2 (ja) 2023-07-06
IL264007B1 (en) 2023-03-01
KR20200016160A (ko) 2020-02-14
TW201905208A (zh) 2019-02-01
CL2019003184A1 (es) 2020-05-22
RU2729688C1 (ru) 2020-08-11
KR102626963B1 (ko) 2024-01-18
NZ748938A (en) 2021-12-24
EP3621735A1 (en) 2020-03-18
CN109689216B (zh) 2022-04-05

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