PE20200648A1 - Revestimientos superficiales, protectores para celdas de flujo - Google Patents

Revestimientos superficiales, protectores para celdas de flujo

Info

Publication number
PE20200648A1
PE20200648A1 PE2019002299A PE2019002299A PE20200648A1 PE 20200648 A1 PE20200648 A1 PE 20200648A1 PE 2019002299 A PE2019002299 A PE 2019002299A PE 2019002299 A PE2019002299 A PE 2019002299A PE 20200648 A1 PE20200648 A1 PE 20200648A1
Authority
PE
Peru
Prior art keywords
functionalized polymer
coating layer
polymer coating
substrate
exposed surface
Prior art date
Application number
PE2019002299A
Other languages
English (en)
Inventor
Sean M Ramirez
Brian D Mather
Edwin Li
Sojeong Moon
Innsu Daniel Kim
Alexandre Richez
Ludovic Vincent
Xavier Von Hatten
Hai Quang Tran
Maxwell Zimmerley
Julia Morrison
Gianluca Andrea Artioli
Krystal Sly
Hayden Black
Lewis J Kraft
Hong Xie
Wei Wei
Ryan Sanford
Original Assignee
Illumina Inc
Illumina Cambridge Ltd
Illumina Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc, Illumina Cambridge Ltd, Illumina Singapore Pte Ltd filed Critical Illumina Inc
Publication of PE20200648A1 publication Critical patent/PE20200648A1/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)

Abstract

Un ejemplo de un metodo incluye proporcionar un sustrato con una superficie expuesta que comprende un primer grupo quimico, en donde la provision comprende opcionalmente modificar la superficie expuesta del sustrato para incorporar el primer grupo quimico; hacer reaccionar el primer grupo quimico con un primer grupo reactivo de una molecula de polimero funcionalizado para formar una capa de revestimiento de polimero funcionalizado unida covalentemente a la superficie expuesta del sustrato; injertar un cebador en la capa de revestimiento de polimero funcionalizado al hacer reaccionar el cebador con un segundo grupo reactivo de la capa de revestimiento de polimero funcionalizado; y formar un revestimiento protector soluble en agua sobre el cebador y la capa de revestimiento de polimero funcionalizado. Ejemplos de celdas de flujo que incorporan ejemplos del revestimiento protector soluble en agua tambien se describen en la presente
PE2019002299A 2017-05-11 2018-05-02 Revestimientos superficiales, protectores para celdas de flujo PE20200648A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762504977P 2017-05-11 2017-05-11
PCT/US2018/030689 WO2018208561A1 (en) 2017-05-11 2018-05-02 Protective surface coatings for flow cells

Publications (1)

Publication Number Publication Date
PE20200648A1 true PE20200648A1 (es) 2020-06-11

Family

ID=64096452

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2019002299A PE20200648A1 (es) 2017-05-11 2018-05-02 Revestimientos superficiales, protectores para celdas de flujo

Country Status (23)

Country Link
US (2) US11667969B2 (es)
EP (1) EP3621735A4 (es)
JP (1) JP7304158B2 (es)
KR (1) KR102626963B1 (es)
CN (1) CN109689216B (es)
AU (1) AU2018266308B2 (es)
BR (1) BR112018077164A2 (es)
CA (1) CA3026659C (es)
CL (1) CL2019003184A1 (es)
CO (1) CO2019012418A2 (es)
CR (1) CR20190552A (es)
IL (1) IL264007B2 (es)
MX (1) MX2018015072A (es)
NL (1) NL2019044B1 (es)
NZ (1) NZ748938A (es)
PE (1) PE20200648A1 (es)
PH (1) PH12019502530A1 (es)
RU (1) RU2729688C1 (es)
SA (1) SA518400716B1 (es)
SG (1) SG11201811460TA (es)
TW (1) TW201905208A (es)
WO (1) WO2018208561A1 (es)
ZA (1) ZA201808187B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ759626A (en) 2017-12-21 2023-03-31 Illumina Inc Flow cells with hydrogel coating
TWI685960B (zh) * 2018-02-03 2020-02-21 美商伊路米納有限公司 使用感測器的主動表面的結構和方法
TW202043486A (zh) * 2019-01-29 2020-12-01 美商伊路米納有限公司 定序套組
TW202045709A (zh) 2019-01-29 2020-12-16 美商伊路米納有限公司 流體槽
CN110055318A (zh) * 2019-05-06 2019-07-26 南京拓远生物科技有限公司 一种基于点击化学的三维dna微阵列表面的制备方法
BR112021012873A2 (pt) * 2019-08-01 2022-02-08 Illumina Inc Célula de fluxo, método para introduzir um fluido e kit
NL2023679B1 (en) * 2019-08-09 2021-04-13 Illumina Inc System and method for patterning flow cell substrates
US11498078B2 (en) * 2019-12-23 2022-11-15 Singular Genomics Systems, Inc. Flow cell receiver and methods of use
AU2021259217A1 (en) * 2020-04-24 2022-01-06 Illumina Cambridge Limited Flow cells
TW202235627A (zh) * 2020-11-16 2022-09-16 英商伊路米納劍橋有限公司 改變流動池訊號
AU2021400828A1 (en) * 2020-12-15 2023-06-22 Illumina, Inc. Flow cell coating methods
US11833503B2 (en) * 2021-12-07 2023-12-05 Insilixa, Inc. Methods and compositions for surface functionalization of optical semiconductor-integrated biochips
WO2023111587A1 (en) * 2021-12-17 2023-06-22 Vidya Holdings Ltd Improvements in or relating to microarray fabrication
US20230350297A1 (en) * 2022-03-22 2023-11-02 Illumina Cambridge Limited Methods for making flow cell surfaces
WO2024044705A1 (en) * 2022-08-26 2024-02-29 Illumina, Inc. Flow cells with patterned bonding regions
US20240132956A1 (en) * 2022-09-29 2024-04-25 Illumina, Inc. Nucleic acid sequencing components including a glycolipid bi-layer

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6589778B1 (en) * 1999-12-15 2003-07-08 Amersham Biosciences Ab Method and apparatus for performing biological reactions on a substrate surface
US20030040129A1 (en) 2001-08-20 2003-02-27 Shah Haresh P. Binding assays using magnetically immobilized arrays
US20060254916A1 (en) * 2005-05-16 2006-11-16 Hernandez Juan J Methods of forming microfluidic devices and uses thereof
JP4797619B2 (ja) 2005-12-22 2011-10-19 東レ株式会社 分析チップおよび被検物質の分析方法
FR2897858B1 (fr) * 2006-02-27 2008-06-20 Commissariat Energie Atomique Procede de fabrication d'un reseau de capillaires d'une puce
EP1845374A1 (en) * 2006-04-14 2007-10-17 Koninklijke Philips Electronics N.V. Form inhibitor membrane for a flow-through cell
EP2214822A1 (en) * 2007-11-26 2010-08-11 Atonomics A/S Integrated separation and detection cartridge using magnetic particles with bimodal size distribution
EP2138233B1 (de) 2008-06-02 2010-10-20 Boehringer Ingelheim microParts GmbH Mikrofluidische Folienstruktur zum Dosierren von Flüssigkeiten
US8822346B1 (en) 2008-06-10 2014-09-02 Intermolecular, Inc. Method and apparatus for self-aligned layer removal
GB2469441B (en) 2009-04-14 2011-07-13 Arrow Coated Products Self-adhesive material with a water-soluble protective layer
EP3305400A3 (en) * 2011-10-28 2018-06-06 Illumina, Inc. Microarray fabrication system and method
US10837879B2 (en) 2011-11-02 2020-11-17 Complete Genomics, Inc. Treatment for stabilizing nucleic acid arrays
JP6257605B2 (ja) 2012-06-05 2018-01-10 スリーエム イノベイティブ プロパティズ カンパニー グラフトコポリマー官能化物品
US9012022B2 (en) 2012-06-08 2015-04-21 Illumina, Inc. Polymer coatings
US9512422B2 (en) 2013-02-26 2016-12-06 Illumina, Inc. Gel patterned surfaces
US20160023208A1 (en) * 2013-03-13 2016-01-28 Illumina, Inc. Multilayer fluidic devices and methods for their fabrication
EP3919624A3 (en) * 2013-07-01 2021-12-29 Illumina, Inc. Catalyst-free surface functionalization and polymer grafting
CN103951797B (zh) 2014-03-17 2017-05-03 江苏诺飞新材料科技有限公司 一种有机硅接枝共聚物及其制备方法和应用
CN107003234B (zh) 2014-07-29 2020-01-21 Ldip有限责任公司 部分封装的基于波导的感测芯片、系统和使用方法
US9533278B2 (en) 2014-08-08 2017-01-03 Applied Materials, Inc. Patterned deposition of liquid films for biomedical devices
EP3218511B1 (en) 2014-11-11 2020-04-22 Illumina Cambridge Limited Methods and arrays for producing and sequencing monoclonal clusters of nucleic acid
EP3332255B1 (en) * 2015-08-06 2020-06-17 Lia Diagnostics, Inc. Water dispersible assays

Also Published As

Publication number Publication date
SA518400716B1 (ar) 2023-02-12
US20230272469A1 (en) 2023-08-31
CO2019012418A2 (es) 2020-05-15
CA3026659A1 (en) 2018-11-15
ZA201808187B (en) 2024-04-24
CN109689216A (zh) 2019-04-26
JP7304158B2 (ja) 2023-07-06
IL264007B2 (en) 2023-07-01
KR102626963B1 (ko) 2024-01-18
EP3621735A1 (en) 2020-03-18
EP3621735A4 (en) 2021-03-24
BR112018077164A2 (pt) 2019-04-02
RU2729688C1 (ru) 2020-08-11
CR20190552A (es) 2020-01-28
IL264007A (en) 2019-01-31
SG11201811460TA (en) 2019-01-30
PH12019502530A1 (en) 2020-06-29
CA3026659C (en) 2022-08-02
TW201905208A (zh) 2019-02-01
NZ748938A (en) 2021-12-24
KR20200016160A (ko) 2020-02-14
CL2019003184A1 (es) 2020-05-22
AU2018266308B2 (en) 2023-05-11
MX2018015072A (es) 2020-01-14
WO2018208561A1 (en) 2018-11-15
US11667969B2 (en) 2023-06-06
NL2019044B1 (en) 2018-11-15
CN109689216B (zh) 2022-04-05
AU2018266308A1 (en) 2019-01-03
IL264007B1 (en) 2023-03-01
JP2020519231A (ja) 2020-07-02
US20180327832A1 (en) 2018-11-15

Similar Documents

Publication Publication Date Title
PE20200648A1 (es) Revestimientos superficiales, protectores para celdas de flujo
WO2016115377A8 (en) Graphene oxide barrier film
CL2017002937A1 (es) Sustrato de papel con recubrimiento hidrófobo para cubiertas superiores de emulsión polimérica y método de elaboración del mismo.
MX2018008028A (es) Composicion de revestimiento de silicon resistente a la recoleccion de suciedad.
WO2016104445A8 (ja) コーティング剤組成物
CL2016001324A1 (es) Método de revestimiento para superficies en instalaciones químicas
SG11201807157QA (en) Anticorrosion coating composition, anticorrosion coating film, substrate with anticorrosion coating film, and method of manufacturing same
CY1111352T1 (el) Συνθεσεις αντιρρυπαντικης επιστρωσης περιεχουσες καρβοξυλο-λειτουργικη οργανοσιλικονη
MY182675A (en) Antifouling paint composition, copolymer for antifouling paint composition and method for manufacturing same, and painted object having on surface antifouling paint film formed using said composition
DE602007006179D1 (de) Barriereschichten für filme und strukturen
MX2019014961A (es) Composicion de recubrimiento curable por radiacion para mejorar las propiedades de la superficie de plasticos.
TW200741299A (en) Methods for protecting glass
WO2012175431A3 (de) Herstellung von folien mit flexiblen barrierebeschichtungen enthaltend schichtsilicate
WO2009011227A1 (ja) 防汚性組成物、表面保護フィルムおよび偏光板の表面保護方法
WO2012175427A3 (de) Herstellung von folien mit flexiblen barrierebeschichtungen enthaltend schichtsilicate
NZ738072A (en) Curable film-forming compositions containing photothermally active materials, coated metal substrates, and methods of coating substrates
GT201700030A (es) Un laminado para inhibir la respuesta de etileno en plantas y un método para preparar el mismo
AR098138A1 (es) Composiciones para recubrimiento de contenedores
TW201712056A (en) Crosslinked coating film having scratch resistance and flexibility, and resin composition
PH12019500576A1 (en) Adhesive sheet for semiconductor processing
ATE469194T1 (de) Klarlackbeschichtungen mit carbinolfunktionellem siloxanharz
WO2007112094A3 (en) Coatings with carbinol- functional siloxane resin
ATE506419T1 (de) Schnell trocknende lacke
WO2012030945A3 (en) Ophthalmic lenses, ophthalmic lens coating compositions, and methods for manufacturing ophthalmic lenses
MX2018010287A (es) Pelicula laminada que comprende copolimero de etileno.