CN215534415U - Vacuum blood collection tube for separating PRP - Google Patents
Vacuum blood collection tube for separating PRP Download PDFInfo
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- CN215534415U CN215534415U CN202122046944.0U CN202122046944U CN215534415U CN 215534415 U CN215534415 U CN 215534415U CN 202122046944 U CN202122046944 U CN 202122046944U CN 215534415 U CN215534415 U CN 215534415U
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- pipe
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- sampling
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- 210000004369 blood Anatomy 0.000 title claims abstract description 21
- 239000008280 blood Substances 0.000 title claims abstract description 21
- 239000007788 liquid Substances 0.000 claims abstract description 38
- 238000005070 sampling Methods 0.000 claims abstract description 38
- 229920001971 elastomer Polymers 0.000 claims abstract description 19
- 229920005549 butyl rubber Polymers 0.000 claims description 8
- 238000002156 mixing Methods 0.000 abstract description 4
- 230000035515 penetration Effects 0.000 abstract 1
- 238000010241 blood sampling Methods 0.000 description 17
- 239000003634 thrombocyte concentrate Substances 0.000 description 12
- 210000002966 serum Anatomy 0.000 description 9
- 210000003743 erythrocyte Anatomy 0.000 description 6
- 239000000284 extract Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 3
- 239000003102 growth factor Substances 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 102000009123 Fibrin Human genes 0.000 description 2
- 108010073385 Fibrin Proteins 0.000 description 2
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 229950003499 fibrin Drugs 0.000 description 2
- 210000004623 platelet-rich plasma Anatomy 0.000 description 2
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- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 description 1
- 102000013275 Somatomedins Human genes 0.000 description 1
- 108010009583 Transforming Growth Factors Proteins 0.000 description 1
- 102000009618 Transforming Growth Factors Human genes 0.000 description 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 description 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
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- 210000004027 cell Anatomy 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
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- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
本实用新型涉及采血管领域，尤其涉及一种用于分离PRP的真空采血管。包括上管和下管，所述上管和下管之间设置有连通管，所述上管的上部螺纹连接有上管帽，所述上管帽的中心设置有凸出其上端面的采样管，所述采样管的外表面开设有与上管上部螺纹方向相反的外螺纹，所述采样管的下端一体成型有直径相同的入液管，所述采样管螺纹连接有采样管帽，所述采样管帽的下端一体成型有连接杆，所述连接杆的下端连接有橡胶塞，所述橡胶塞进入入液管将其密封。本新型可以减小PRP与上、下液面的相接面积，进而减小互相的渗透和混合，提高纯度，同时设置直达PRP层的入液管，可以更加方便的提取血小板浓缩液。
The utility model relates to the field of blood collection tubes, in particular to a vacuum blood collection tube for separating PRP. It includes an upper pipe and a lower pipe, a communication pipe is arranged between the upper pipe and the lower pipe, an upper pipe cap is threadedly connected to the upper part of the upper pipe, and the center of the upper pipe cap is provided with a sampler protruding from its upper end surface The outer surface of the sampling pipe is provided with an external thread opposite to the thread direction of the upper part of the upper pipe, the lower end of the sampling pipe is integrally formed with a liquid inlet pipe with the same diameter, and the sampling pipe is threadedly connected with a sampling pipe cap, so The lower end of the sampling pipe cap is integrally formed with a connecting rod, and the lower end of the connecting rod is connected with a rubber plug, and the rubber plug enters the liquid inlet pipe to seal it. The new type can reduce the contact area between PRP and the upper and lower liquid surfaces, thereby reducing mutual penetration and mixing, and improving the purity.
Description
Technical Field
The utility model relates to the field of blood collection tubes, in particular to a vacuum blood collection tube for separating PRP.
Background
PRP is a platelet concentrate extracted from whole blood by centrifugation, and contains high concentrations of platelets (which release more than 30 growth factors upon platelet activation), leukocytes, and fibrin. The PRP can promote the repair of bones and soft tissues, and after being activated (without being activated in an injection body), the PRP releases more than 30 growth factors with high concentration, such as platelet-derived growth factors, transforming factor beta, insulin-like growth factors, vascular endothelial growth factors, epidermal growth factors and the like, and the growth factors can accelerate the differentiation of mesenchymal stem cells, promote the proliferation of osteoblasts and fibroblasts and accelerate the synthesis of fibrin and extracellular matrix. Is helpful for blocking the damaged vessel wall, contracting the lacerated opening of the vessel and preventing the further bleeding of the damaged tissue. It is a biological scaffold, can be used for screening cells and platelets, and is beneficial to the creeping and adhesion of stem cells repaired around. PRP preparation requires centrifugation of the blood through PRP tubes to obtain platelet concentrates.
The existing PRP test tube is prepared by placing a test tube with collected blood into a centrifuge, then centrifuging again, separating into serum, platelet concentrate and red blood cells, and then sequentially extracting through a syringe needle. However, in the process of drawing, since the upper serum needs to be drawn first and then the platelet concentrate needs to be drawn, on one hand, the needle is easy to be directly inserted into the platelet concentrate from the serum during the drawing for medical care, so that the purity of the platelet concentrate is reduced, and on the other hand, because the content of the platelet concentrate is low, the contact surfaces of the existing tube bodies with equal diameters and the upper and lower liquid surfaces are large, the two liquid bodies are easy to mix with each other, and the actual drawing is difficult.
SUMMERY OF THE UTILITY MODEL
In view of the above problems, the present invention is directed to provide a vacuum blood collection tube for separating PRP, which can reduce the contact area between PRP and the upper and lower liquid surfaces, reduce mutual permeation and mixing, improve purity, and provide a liquid inlet tube directly reaching the PRP layer, thereby more conveniently extracting platelet concentrate.
In order to achieve the purpose, the technical scheme adopted by the utility model is as follows:
the utility model provides a vacuum test tube for separating PRP, includes top tube and low tube, be provided with communicating pipe between top tube and the low tube, the upper portion threaded connection of top tube has the top tube cap, the center of top tube cap is provided with the sampling tube of protrusion up end, the surface of sampling tube set up with top tube upper portion screw thread opposite direction's external screw thread, the lower extreme integrated into one piece of sampling tube has the inlet tube that the diameter is the same, sampling tube threaded connection has the sampling tube cap, the lower extreme integrated into one piece of sampling tube cap has the connecting rod, the lower extreme of connecting rod is connected with the rubber buffer, the rubber buffer gets into the inlet tube and seals it.
Preferably, the inside of the upper pipe cap is provided with a butyl rubber plug, the upper pipe cap is further provided with a blood sampling hole, and the blood sampling hole is provided with a blood sampling hole plug in a matching manner.
Preferably, the lower end of the lower pipe is in threaded connection with a lower pipe cap, and a liquid outlet of the rubber body is formed in the lower pipe cap.
Preferably, the outer wall of the sampling tube cap is provided with anti-slip stripes.
Preferably, the lower end of the upper pipe and the upper end of the lower pipe are both cones, and the lower end of the liquid inlet pipe is located in the cone space at the lower end of the upper pipe.
Preferably, the lower end face of the rubber plug is flush with the lower end face of the liquid inlet pipe.
Compared with the prior art, the utility model has the beneficial effects that:
1. the novel liquid inlet pipe capable of directly reaching the PRP layer is arranged, the problem that the pollution is caused by the fact that the needle head firstly extracts upper serum and then extracts platelets is avoided, meanwhile, the needle head penetrates through the lower end of the liquid inlet pipe and enters the PRP layer, then the needle head can move up and down to a certain height, the platelets are completely extracted, and medical staff are prevented from being accidentally inserted into the PRP layer when serum is extracted;
2. the liquid inlet pipe is provided with the sealing rubber plug, so that the problem of mixing caused by the fact that liquid is filled in the liquid inlet pipe in the centrifugal process and then platelets are extracted is solved;
3. the novel upper pipe cap and the sampling pipe cap have opposite thread directions, so that the technical effect of screwing the upper pipe cap when the sampling pipe cap is unscrewed can be achieved, and the leakage of liquid caused by simultaneous unscrewing is avoided;
4. the butyl rubber plug is arranged in the upper pipe cap, so that the sealing effect can be further achieved;
5. the lower tube cap is provided with a liquid outlet, and red blood cells can be directly extracted through the liquid outlet if the red blood cells need to be directly extracted.
Drawings
The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the principles of the utility model and not to limit the utility model.
In the drawings:
fig. 1 is a schematic structural view of the liquid inlet pipe of the present invention.
Fig. 2 is a schematic structural diagram of the present invention.
FIG. 3 is a schematic structural view of the present invention without an upper cap.
Fig. 4 is a front structural diagram of the upper pipe cap.
Fig. 5 is a schematic view of the forward structure of the sampling tube cap.
Fig. 6 is a schematic view of an inverted structure of the sampling tube cap.
Fig. 7 is a cross-sectional view of the upper cap.
Wherein: 1. the blood sampling device comprises an upper pipe, a lower pipe, a communicating pipe, a lower pipe cap, a liquid outlet, a butyl rubber plug, an external thread, a sampling pipe cap, a connecting rod, a rubber plug, a liquid inlet pipe, a blood sampling hole plug, a sampling hole plug and an anti-skid stripe, wherein the upper pipe, the lower pipe, the communicating pipe, the sampling pipe cap, the liquid outlet, the butyl rubber plug, the external thread, the sampling pipe cap, the connecting rod, the rubber plug, the liquid inlet pipe, the sampling hole plug, the blood sampling hole plug and the anti-skid stripe are arranged in sequence from top to bottom, and the anti-skid device comprises a base, a connecting rod and a connecting rod.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are described herein for the purpose of illustration and explanation and not limitation.
Example (b):
referring to FIGS. 1-7, a vacuum blood collection tube for separating PRP comprises an upper tube 1 and a lower tube 2, the heights of the upper pipe 1 and the lower pipe 2 are the same, the lower end of the upper pipe 1 and the upper end of the lower pipe 2 are both cones, the connection area of the PRP and the upper and lower liquid surfaces can be reduced, thereby reducing mutual permeation and mixing, improving purity, and simultaneously arranging a liquid inlet pipe which directly reaches the PRP layer, can more conveniently extract platelet concentrate, a communicating pipe 3 is arranged between the upper pipe 1 and the lower pipe 2, the upper part of the upper tube 1 is connected with an upper tube cap 9 through screw threads, a sampling tube 8 which protrudes out of the upper end surface of the upper tube cap 9 is arranged in the center of the upper tube cap 9, the outer surface of the sampling pipe 8 is provided with an external thread 7 with the direction opposite to that of the upper thread of the upper pipe 1, and then can reach the technical effect of screwing the upper tube cap when unscrewing the sampling tube cap, avoid simultaneously unscrewing and cause revealing of liquid.
The lower extreme integrated into one piece of sampling pipe 8 has liquid inlet pipe 13 that the diameter is the same, the lower extreme of liquid inlet pipe 13 is located the cone space of the lower extreme of upper tube 1. Because the content of the separated red blood cells is slightly more than that of serum, platelet-rich plasma is approximately positioned in cones at the lower end of the upper tube 1 and the upper end of the lower tube 2, and therefore the platelet-rich plasma directly reaches the liquid inlet tube of the PRP layer, the problem that the needle extracts the upper serum layer first and then extracts platelets to cause pollution is avoided, meanwhile, the needle can move up and down on the PRP layer after penetrating through the lower end of the liquid inlet tube to enter the PRP layer, platelets are completely extracted, and medical staff is prevented from being inserted into the PRP layer when extracting the serum carelessly;
8 threaded connection of sampling pipe has sampling pipe cap 10, the lower extreme integrated into one piece of sampling pipe cap 10 has connecting rod 11, connecting rod 11 is the medical plastics of stereoplasm, and its diameter is less than the internal diameter of inlet tube 13, the lower extreme of connecting rod 11 bonds has rubber buffer 12, and rubber buffer 12's diameter is the same with the internal diameter of inlet tube 13, the lower terminal surface of rubber buffer 12 and the lower terminal surface parallel and level of inlet tube 13, rubber buffer 12 gets into inlet tube 13 and seals it, has avoided also being full of liquid in the inlet tube in centrifugal process, and then has leaded to the mixed problem that can cause when drawing the platelet.
Go up the inside of pipe cap 9 and be provided with butyl rubber stopper 6, the diameter of butyl rubber stopper 6 is the same with the internal diameter of upper tube 1, and then can further play sealed effect. The upper pipe cap 9 is further provided with a blood sampling hole 14, the blood sampling hole 14 is provided with a blood sampling hole plug 15 in a matching mode, the needle can directly penetrate into the butyl rubber plug 6 body below the blood sampling hole 14 during blood sampling, and the blood sampling hole plug 15 is made of medical rubber materials and can achieve the effects of sealing, dust prevention and bacteria prevention.
The lower extreme threaded connection of low tube 2 has lower tube cap 4, be provided with the liquid outlet 5 of the rubber body on lower tube cap 4, can directly pass through the syringe needle during the use and extract red blood cell can.
The outer wall of the sampling tube cap 10 is provided with anti-slip stripes 17, which is convenient for medical staff to screw.
The principle and the using process of the utility model are as follows:
and opening the blood sampling hole plug 15, inserting the needle into the blood sampling hole 14 to finish blood collection, plugging the blood sampling hole plug 15, putting the blood sampling hole plug into a centrifuge for separation, and separating the blood sampling tube into serum, platelet concentrate and red blood cells from top to bottom in sequence after centrifugation, wherein the platelet concentrate is positioned in the middle. The sampling tube cap 10 is unscrewed and pulled out, then the sampling needle is inserted into the sampling tube 8 and then enters the liquid inlet tube 13 and penetrates out, and then the extraction of the platelet concentrate is finished.
The foregoing shows and describes the general principles, essential features, and advantages of the utility model. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the utility model as claimed. The scope of the utility model is defined by the appended claims and equivalents thereof.
Claims (6)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122046944.0U CN215534415U (en) | 2021-08-27 | 2021-08-27 | Vacuum blood collection tube for separating PRP |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122046944.0U CN215534415U (en) | 2021-08-27 | 2021-08-27 | Vacuum blood collection tube for separating PRP |
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| Publication Number | Publication Date |
|---|---|
| CN215534415U true CN215534415U (en) | 2022-01-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202122046944.0U Active CN215534415U (en) | 2021-08-27 | 2021-08-27 | Vacuum blood collection tube for separating PRP |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114010659A (en) * | 2021-11-23 | 2022-02-08 | 新疆维吾尔自治区人民医院 | A kind of preparation method of platelet rich plasma |
| CN114887681A (en) * | 2022-06-13 | 2022-08-12 | 杭州博科迈生物科技有限公司 | Platelet-rich plasma separation device |
-
2021
- 2021-08-27 CN CN202122046944.0U patent/CN215534415U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114010659A (en) * | 2021-11-23 | 2022-02-08 | 新疆维吾尔自治区人民医院 | A kind of preparation method of platelet rich plasma |
| CN114010659B (en) * | 2021-11-23 | 2023-09-29 | 新疆维吾尔自治区人民医院 | A kind of preparation method of platelet-rich plasma |
| CN114887681A (en) * | 2022-06-13 | 2022-08-12 | 杭州博科迈生物科技有限公司 | Platelet-rich plasma separation device |
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