CN114887681A - Platelet-rich plasma separation device - Google Patents
Platelet-rich plasma separation device Download PDFInfo
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- CN114887681A CN114887681A CN202210659716.7A CN202210659716A CN114887681A CN 114887681 A CN114887681 A CN 114887681A CN 202210659716 A CN202210659716 A CN 202210659716A CN 114887681 A CN114887681 A CN 114887681A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B7/00—Elements of centrifuges
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Abstract
The invention relates to a platelet-rich plasma separation device, which comprises a sealing rod and a necking section, wherein the sealing rod consists of an upper section and a lower section which are coaxial, the necking section consists of an upper hollow inverted circular truncated cone section, a middle hollow cylindrical section and a lower hollow circular truncated cone section which are coaxial, the lower section of the sealing rod is in interference fit with the middle hollow cylindrical section of the necking section, the whole sealing rod is of a hollow tube structure, and the lower section of the sealing rod is of a hollow inverted circular truncated cone structure. The platelet-rich plasma separation device has good sealing property, can improve the extraction rate of the enrichment substance, realizes ultra-pure extraction, and can be conveniently operated by operators.
Description
Technical Field
The invention belongs to the technical field of separation devices, and relates to a platelet-rich plasma separation device.
Background
The platelet-rich plasma separation device on the market at present basically adopts the structural design of necking sections with thick ends and thin middle parts, and then the necking sections are in interference fit with a sealing rod fixed on an upper cover, so that the aim of sealing a tube on the separation device is fulfilled, wherein the sealing rod consists of an upper section and a lower section which are coaxial, the necking sections consist of an upper hollow inverted circular truncated cone section, a middle hollow cylindrical section and a lower hollow circular truncated cone section which are coaxial, and the lower section of the sealing rod is in interference fit with the middle hollow cylindrical section of the necking sections. However, the sealing rod is of a solid structure, the length of the sealing rod is long, the deformation amount is large, central axes of the sealing rod, the necking section and the upper cover cannot be completely overlapped and deviate greatly, and meanwhile, due to the fact that the interference fit mode of the lower section of the sealing rod and the middle hollow cylindrical section of the necking section is shown in fig. 1, the sealing rod is difficult to be perfectly blocked at the center of the necking section, the problem of poor sealing performance is prone to occurring, and the phenomenon of liquid seepage is prone to occurring. Meanwhile, the primary centrifugal product of the platelet-rich plasma separation device is three layers, the clear liquid is on the upper layer, and the target enriched liquid is on the middle layer; the secondary centrifugal product is divided into two layers, the clear liquid is on the upper layer, and the target enrichment liquid is on the lower layer; the upper cover is provided with an extraction hole (the diameter is 5 mm), the needle passes through the extraction hole and the upper layer of clear liquid penetrates into the middle layer or the lower layer of target enrichment liquid, and in the process of extracting the target enrichment liquid, the needle can shake in the upper layer of clear liquid, so that the layering condition of the separated enrichment liquid is changed, and the extraction rate of the enrichment is reduced.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides a platelet-rich plasma separation device.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
the utility model provides a rich platelet plasma separator, includes sealing rod and necking down section, and the sealing rod comprises coaxial upper segment and hypomere, and the necking down section comprises coaxial upper portion cavity radius bench section, middle cavity cylinder section and lower part cavity round bench section, and the hypomere of sealing rod and the middle cavity cylinder section interference fit of necking down section, its characterized in that, the whole hollow tube structure that is of sealing rod, the hypomere of sealing rod is cavity radius bench structure.
As a preferred technical scheme:
in the platelet-rich plasma separation device, the upper section of the sealing rod is of a hollow cylindrical structure.
In the platelet-rich plasma separation device, the outer diameter of the upper section of the sealing rod is equal to the outer diameter of the large end of the lower section of the sealing rod, the wall thickness of the upper section of the sealing rod is t1, and the wall thickness of the lower section of the sealing rod is gradually reduced from t1 to 0 from top to bottom.
According to the platelet-rich plasma separation device, the length of the upper section of the sealing rod is 58.3mm, and the outer diameter of the sealing rod is 7.0-7.6 mm; the length of the lower section of the sealing rod is 2.5-5 mm, and the taper is 58-75 degrees; t1 is 1 mm.
According to the platelet-rich plasma separation device, the length of the middle hollow cylindrical section of the neck section is 8mm, the wall thickness is t2, the outer diameter is d, d is 7.0-7.6 mm, and t2 is 1 mm.
According to the platelet-rich plasma separation device, the wall thicknesses of the upper hollow circular truncated cone section and the lower hollow circular truncated cone section of the neck section are both t2, and the outer diameters of the small ends are both d; the length of the hollow inverted circular truncated cone section at the upper part of the neck-reducing section is 11.7mm, and the taper is 45 degrees; the length of the hollow circular platform section at the lower part of the necking section is 11.7mm, and the taper is 45 degrees.
The reasons for the above dimensional parameter settings are as follows:
the outer diameter of the upper section of the sealing rod, the length of the lower section of the sealing rod, the taper of the lower section of the sealing rod and the outer diameter of the middle hollow cylindrical section of the necking section can influence the enrichment rate of the platelet-rich plasma separation device, and higher enrichment rate can be obtained by reasonably setting the value ranges of the parameters;
the conicity of the upper hollow inverted circular truncated cone section and the lower hollow circular truncated cone section of the neck-reducing section is 45 degrees, so that the structural strength of the neck-reducing section is reliable.
The platelet-rich plasma separation device has the enrichment rate of over 86 percent and good or excellent sealing property;
the enrichment ratio test method comprises the following steps: diluting a quantitative enrichment solution by using a diluent, measuring the platelet concentration of the enrichment solution in a blood analyzer, and reflecting the enrichment rate by using the platelet concentration; enrichment rate is the number of platelets in the enriched fluid/the number of platelets in the blood before centrifugation, wherein the number of platelets before centrifugation is the blood volume platelet concentration and all concentration measurements are from a blood analyzer;
the tightness test method comprises the following steps: injecting the toluidine blue reagent into a platelet-rich plasma separation device, and then placing the platelet-rich plasma separation device into a centrifuge for centrifugation (the centrifugation speed is 3000rpm, and the centrifugation time is 3 min); before centrifugation, a paper sheet A4 was stuck to the inside (side) of the centrifuge, a square of 21cm × 29cm and 1cm × 1cm was drawn on the paper sheet A4, and after the centrifugation was completed, it was carefully confirmed that the paper sheet A4 stuck to the inside of the centrifuge had no blue liquid mark and had no leakage at the sample connection site (upper lid); if the number of the contaminated squares on the paper is 0, the sealing performance is excellent; if the number of the contaminated squares on the paper is 1 or 2, the sealing property is good; if the number of the polluted squares on the paper is 3, 4, 5 or 6, the sealing performance is normal; if the number of the squares contaminated on the paper is 7 or more, the sealing property is poor.
The principle of the invention is as follows:
aiming at the problem of poor sealing of the platelet-rich plasma separation device in the prior art, the invention changes the sealing rod from a solid rod into a hollow tube, and the tail end of the hollow tube is used as a conical surface. The hollow tube is tubular structure, and tubular structure compares solid core construction of solid bar and will be stronger than solid core construction in intensity, and the deformation volume also can be less than solid core construction, therefore sealing rod, necking down section and upper cover three's axiality are higher. After the tail end of the hollow pipe is designed to be in a conical surface structure, the tail end of the hollow pipe can more smoothly form interference fit with the middle hollow cylindrical section of the necking section, and good sealing performance of the structure is guaranteed (as shown in figure 3).
Meanwhile, the sealing rod is changed from a solid rod into a hollow pipe, the hollow pipe is used as an enrichment substance suction pipe in the process of extracting the target enrichment liquid, only a small part of clear liquid enters the hollow pipe, the contact between a needle head and the supernatant liquid and the disturbance of an operator to the layering state in the extraction process can be reduced, the extraction rate of the enrichment substance is improved, and the ultra-pure extraction is realized.
Has the beneficial effects that:
(1) the platelet-rich plasma separation device has good sealing property;
(2) the platelet-rich plasma separation device can improve the extraction rate of the enrichment substance and realize ultrapure extraction;
(3) the platelet-rich plasma separation device can be operated by operators conveniently.
Drawings
FIG. 1 is a schematic diagram of a prior art platelet rich plasma separation device;
FIG. 2 is a schematic structural view of a seal bar of the present invention;
FIG. 3 is a schematic diagram of the structure of the platelet rich plasma separation device of the present invention;
wherein, 1-sealing rod, 1.1-upper segment, 1.2-lower segment, 2-neck segment, 2.1-upper hollow inverted circular truncated cone segment, 2.2-middle hollow cylindrical segment, and 2.3-lower hollow circular truncated cone segment.
Detailed Description
The invention will be further illustrated with reference to specific embodiments. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Further, it should be understood that various changes or modifications of the present invention may be made by those skilled in the art after reading the teaching of the present invention, and such equivalents may fall within the scope of the present invention as defined in the appended claims.
Example 1
A platelet-rich plasma separation device is shown in figures 2 and 3 and comprises a sealing rod 1 and a necking section 2;
the whole sealing rod 1 is of a hollow tube structure, and the sealing rod 1 consists of an upper section 1.1 with a hollow cylindrical structure and a lower section 1.2 with a hollow inverted round platform structure which are coaxial; the length of the upper section 1.1 of the sealing rod 1 is 58.3mm, the outer diameter is 7.1mm, the wall thickness is t1, and t1 is 1 mm; the outer diameter of the large end of the lower section 1.2 of the sealing rod 1 is equal to that of the upper section 1.1 of the sealing rod 1, the length of the lower section 1.2 of the sealing rod 1 is 2.5mm, the taper is 58 degrees, and the wall thickness of the lower section 1.2 of the sealing rod 1 is gradually reduced to 0 from top to bottom from t 1;
the necking section 2 consists of an upper hollow inverted circular truncated cone section 2.1, a middle hollow cylindrical section 2.2 and a lower hollow circular truncated cone section 2.3 which are coaxial; the length of the upper hollow inverted circular truncated cone section 2.1 of the neck section 2 is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; the middle hollow cylindrical section 2.2 of the neck section 2 has a length of 8mm, wall thickness of t2 and outer diameter of d; the length of a hollow circular platform section 2.3 at the lower part of the neck section 2 is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; d is 7.1mm, t2 is 1 mm;
the lower section 1.2 of the sealing rod 1 is in interference fit with the middle hollow cylindrical section of the necking section 2.
The enrichment rate of the platelet-rich plasma separation device is 88%, and the sealing performance is excellent.
Comparative example 1
A platelet rich plasma separation device substantially as in example 1 except that the outer diameter d of the small end of the upper hollow rounded off section of the neck section is 8.5 mm.
The enrichment ratio of the platelet rich plasma separation device is 87%.
Comparative example 2
A platelet rich plasma separation device substantially as in example 1 except that the upper section of the sealing rod has an outer diameter of 8.5 mm.
The enrichment ratio of the platelet rich plasma separation device is 85%.
Comparative example 3
A platelet rich plasma separation device substantially as in example 1 except that the taper of the lower section of the sealing rod is 45 °.
The enrichment ratio of the platelet-rich plasma separation device is 84%.
Comparative example 4
A platelet rich plasma separation device, substantially as in example 1, except that the length of the lower section of the sealing rod is 0.5 mm.
The enrichment ratio of the platelet rich plasma separation device is 70%.
Experiments show that the outer diameter of the upper section of the sealing rod, the length of the lower section of the sealing rod, the taper of the lower section of the sealing rod and the outer diameter of the middle hollow cylindrical section of the necking section in the size parameters of the platelet-rich plasma separation device can influence the enrichment rate of the platelet-rich plasma separation device, the influence of other size parameters on the enrichment rate of the platelet-rich plasma separation device is almost negligible, and the comparison between the example 1 and the comparative examples 1 to 4 also proves the above view.
Comparative example 5
A platelet-rich plasma separation device, substantially the same as example 1, except that the lower section of the sealing rod has a hollow cylindrical structure, the length of the lower section of the sealing rod is the same as that of the lower section of the sealing rod of example 1, and the outer diameter and the wall thickness of the lower section of the sealing rod are the same as those of the upper section of the sealing rod of example 1, namely, comparative example 5 is different from example 1 only in that the end of the sealing rod is not provided with a tapered surface.
The enrichment rate of the platelet-rich plasma separation device is 79 percent, and the sealing property is general.
Comparing example 1 with comparative example 5, it can be seen that example 1 effectively solves the problem of poor sealability of comparative example 5 by using the end of the sealing rod as a tapered surface.
Comparative example 6
A platelet rich plasma separation device substantially the same as example 1 except that the sealing rod is a solid rod, the length of the sealing rod is equal to that of example 1, and the diameter of the sealing rod is equal to the outer diameter of the upper section of the sealing rod of example 1, namely, comparative example 6 is different from example 1 in that the sealing rod is not provided with a hollow tube on one hand, and the end of the sealing rod is not provided with a tapered surface on the other hand.
The enrichment rate of the platelet-rich plasma separation device is 67%, and the sealing performance is general.
Comparing example 1 with comparative example 6, it can be seen that example 1 effectively solves the problems of low enrichment ratio and poor sealing performance of comparative example 6 by changing the sealing rod from a solid rod into a hollow tube and using the end of the hollow tube as a conical surface.
Example 2
A platelet-rich plasma separation device comprises a sealing rod and a neck-reducing section;
the whole sealing rod is of a hollow pipe structure and consists of an upper section with a hollow cylindrical structure and a lower section with a hollow inverted frustum structure which are coaxial; the length of the upper section of the sealing rod is 58.3mm, the outer diameter is 7.2mm, the wall thickness is t1, and t1 is 1 mm; the outer diameter of the large end of the lower section of the sealing rod is equal to that of the upper section of the sealing rod, the length of the lower section of the sealing rod is 3mm, the taper is 63 degrees, and the wall thickness of the lower section of the sealing rod is gradually reduced to 0 from top to bottom from t 1;
the neck reducing section consists of an upper hollow inverted circular truncated cone section, a middle hollow cylindrical section and a lower hollow circular truncated cone section which are coaxial; the length of the hollow inverted circular truncated cone section at the upper part of the necking section is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; the length of the middle hollow cylindrical section of the necking section is 8mm, the wall thickness is t2, and the outer diameter is d; the length of the hollow circular platform section at the lower part of the necking section is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; d is 7.2mm, t2 is 1 mm;
the lower section of the sealing rod is in interference fit with the middle hollow cylindrical section of the necking section.
The enrichment rate of the platelet-rich plasma separation device is 89%, and the sealing performance is excellent.
Comparative example 7
A platelet-rich plasma separation device, substantially the same as example 2, except that the lower section of the sealing rod has a hollow cylindrical structure, the length of the lower section of the sealing rod is the same as that of the lower section of the sealing rod of example 2, and the outer diameter and the wall thickness of the lower section of the sealing rod are the same as those of the upper section of the sealing rod of example 2, namely, comparative example 7 is different from example 2 only in that the end of the sealing rod is not provided with a tapered surface.
The enrichment rate of the platelet-rich plasma separation device is 77%, and the sealing performance is general.
Comparing example 2 with comparative example 7, it can be seen that example 2 effectively solves the problem of poor sealing performance of comparative example 7 by using the end of the sealing rod as a tapered surface.
Comparative example 8
A platelet rich plasma separation device substantially the same as example 2 except that the sealing rod is a solid rod, the length of the sealing rod is equal to that of example 2, and the diameter of the sealing rod is equal to the outer diameter of the upper section of the sealing rod of example 2, namely, comparative example 8 is different from example 2 in that the sealing rod is not provided with a hollow tube on one hand, and the end of the sealing rod is not provided with a conical surface on the other hand.
The enrichment rate of the platelet-rich plasma separation device is 76%, and the sealing property is general.
Comparing example 2 with comparative example 8, it can be seen that example 2 effectively solves the problems of low enrichment ratio and poor sealing performance of comparative example 8 by changing the sealing rod from a solid rod into a hollow tube and using the end of the hollow tube as a conical surface.
Example 3
A platelet-rich plasma separation device comprises a sealing rod and a neck-reducing section;
the whole sealing rod is of a hollow pipe structure and consists of an upper section with a hollow cylindrical structure and a lower section with a hollow inverted frustum structure which are coaxial; the length of the upper section of the sealing rod is 58.3mm, the outer diameter is 7.3mm, the wall thickness is t1, and t1 is 1 mm; the outer diameter of the large end of the lower section of the sealing rod is equal to that of the upper section of the sealing rod, the length of the lower section of the sealing rod is 3.5mm, the taper is 68 degrees, and the wall thickness of the lower section of the sealing rod is gradually reduced to 0 from top to bottom from t 1;
the neck reducing section consists of an upper hollow inverted circular truncated cone section, a middle hollow cylindrical section and a lower hollow circular truncated cone section which are coaxial; the length of the hollow inverted circular truncated cone section at the upper part of the necking section is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; the length of the middle hollow cylindrical section of the necking section is 8mm, the wall thickness is t2, and the outer diameter is d; the length of the hollow circular platform section at the lower part of the necking section is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; d is 7.3mm, t2 is 1 mm;
the lower section of the sealing rod is in interference fit with the middle hollow cylindrical section of the necking section.
The enrichment rate of the platelet-rich plasma separation device is 94%, and the sealing performance is excellent.
Comparative example 9
A platelet-rich plasma separation device, substantially the same as example 3, except that the lower section of the sealing rod has a hollow cylindrical structure, the length of the lower section of the sealing rod is the same as that of the lower section of the sealing rod of example 3, and the outer diameter and the wall thickness of the lower section of the sealing rod are the same as those of the upper section of the sealing rod of example 3, namely comparative example 9 is different from example 3 only in that the end of the sealing rod is not provided with a tapered surface.
The enrichment ratio of the platelet-rich plasma separation device is 83%, and the sealing performance is good.
Comparing example 3 with comparative example 9, it can be seen that example 3 effectively solves the problem of poor sealing performance of comparative example 9 by using the end of the sealing rod as a tapered surface.
Comparative example 10
A platelet-rich plasma separating device, substantially the same as in example 3, except that the sealing rod is a solid rod, has a length equal to that of the sealing rod of example 3 and a diameter equal to the outer diameter of the upper section of the sealing rod of example 3, i.e., comparative example 10 differs from example 3 in that the sealing rod is not provided as a hollow tube on the one hand and a tapered surface is not provided at the tip of the sealing rod on the other hand.
The enrichment rate of the platelet-rich plasma separation device is 76%, and the sealing performance is good.
Comparing example 3 with comparative example 10, it can be seen that example 3 effectively solves the problems of low enrichment ratio and poor sealing performance of comparative example 10 by changing the sealing rod from a solid rod into a hollow tube and using the end of the hollow tube as a conical surface.
Example 4
A platelet-rich plasma separation device comprises a sealing rod and a neck-reducing section;
the whole sealing rod is of a hollow pipe structure and consists of an upper section with a hollow cylindrical structure and a lower section with a hollow inverted frustum structure which are coaxial; the length of the upper section of the sealing rod is 58.3mm, the outer diameter is 7.4mm, the wall thickness is t1, and t1 is 1 mm; the outer diameter of the large end of the lower section of the sealing rod is equal to that of the upper section of the sealing rod, the length of the lower section of the sealing rod is 4mm, the taper is 72 degrees, and the wall thickness of the lower section of the sealing rod is gradually reduced to 0 from top to bottom from t 1;
the neck reducing section consists of an upper hollow inverted circular truncated cone section, a middle hollow cylindrical section and a lower hollow circular truncated cone section which are coaxial; the length of the hollow inverted circular truncated cone section at the upper part of the necking section is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; the length of the middle hollow cylindrical section of the necking section is 8mm, the wall thickness is t2, and the outer diameter is d; the length of the hollow circular platform section at the lower part of the necking section is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; d is 7.4mm, t2 is 1 mm;
the lower section of the sealing rod is in interference fit with the middle hollow cylindrical section of the necking section.
The enrichment rate of the platelet-rich plasma separation device is 92%, and the sealing performance is excellent.
Comparative example 11
A platelet-rich plasma separation device, substantially the same as example 4, except that the lower section of the sealing rod has a hollow cylindrical structure, the length of the lower section of the sealing rod is the same as that of the lower section of the sealing rod of example 4, and the outer diameter and the wall thickness of the lower section of the sealing rod are the same as those of the upper section of the sealing rod of example 4, namely comparative example 11 is different from example 4 only in that the end of the sealing rod is not provided with a tapered surface.
The enrichment rate of the platelet-rich plasma separation device is 81%, and the sealing property is general.
Comparing example 4 with comparative example 11, it can be seen that example 4 effectively solves the problem of poor sealing performance of comparative example 11 by using the end of the sealing rod as a tapered surface.
Comparative example 12
A platelet rich plasma separating device, substantially the same as example 4 except that the sealing rod is a solid rod, the length of the sealing rod is equal to that of example 4, and the diameter of the sealing rod is equal to the outer diameter of the upper section of the sealing rod of example 4, namely comparative example 12 is different from example 4 in that the sealing rod is not provided with a hollow tube on one hand, and the end of the sealing rod is not provided with a tapered surface on the other hand.
The enrichment rate of the platelet-rich plasma separation device is 77%, and the sealing performance is general.
Comparing example 4 with comparative example 12, it can be seen that example 4 effectively solves the problems of low enrichment ratio and poor sealing performance of comparative example 12 by changing the sealing rod from a solid rod into a hollow tube and using the end of the hollow tube as a conical surface.
Example 5
A platelet-rich plasma separation device comprises a sealing rod and a neck-reducing section;
the whole sealing rod is of a hollow pipe structure and consists of an upper section with a hollow cylindrical structure and a lower section with a hollow inverted frustum structure which are coaxial; the length of the upper section of the sealing rod is 58.3mm, the outer diameter is 7.5mm, the wall thickness is t1, and t1 is 1 mm; the outer diameter of the large end of the lower section of the sealing rod is equal to that of the upper section of the sealing rod, the length of the lower section of the sealing rod is 4.5mm, the taper is 75 degrees, and the wall thickness of the lower section of the sealing rod is gradually reduced to 0 from top to bottom from t 1;
the neck reducing section consists of an upper hollow inverted circular truncated cone section, a middle hollow cylindrical section and a lower hollow circular truncated cone section which are coaxial; the length of the hollow inverted circular truncated cone section at the upper part of the necking section is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; the length of the middle hollow cylindrical section of the necking section is 8mm, the wall thickness is t2, and the outer diameter is d; the length of the hollow circular platform section at the lower part of the necking section is 11.7mm, the taper is 45 degrees, the outer diameter of the small end is d, and the wall thickness is t 2; d is 7.5mm, t2 is 1 mm;
the lower section of the sealing rod is in interference fit with the middle hollow cylindrical section of the necking section.
The enrichment rate of the platelet-rich plasma separation device is 90%, and the sealing performance is good.
Comparative example 13
A platelet-rich plasma separation device, substantially the same as example 5, except that the lower section of the sealing rod has a hollow cylindrical structure, the length of the lower section of the sealing rod is the same as that of the lower section of the sealing rod of example 5, and the outer diameter and the wall thickness of the lower section of the sealing rod are the same as those of the upper section of the sealing rod of example 5, namely comparative example 13 is different from example 5 only in that the end of the sealing rod is not provided with a tapered surface.
The enrichment rate of the platelet-rich plasma separation device is 82%, and the sealing property is general.
Comparing example 5 with comparative example 13, it can be seen that example 5 effectively solves the problem of poor sealing performance of comparative example 13 by using the end of the sealing rod as a tapered surface.
Comparative example 14
A platelet-rich plasma separating device, substantially the same as in example 5, except that the sealing rod is a solid rod, has a length equal to that of the sealing rod of example 5 and a diameter equal to the outer diameter of the upper section of the sealing rod of example 5, i.e., comparative example 14 differs from example 5 in that the sealing rod is not provided as a hollow tube on the one hand and a tapered surface is not provided at the tip of the sealing rod on the other hand.
The enrichment rate of the platelet-rich plasma separation device is 74%, and the sealing performance is general.
Comparing example 5 with comparative example 14, it can be seen that example 5 effectively solves the problems of low enrichment ratio and poor sealing performance of comparative example 14 by changing the sealing rod from a solid rod into a hollow tube and using the end of the hollow tube as a conical surface.
Claims (7)
1. The utility model provides a rich platelet plasma separator, includes sealing rod and necking down section, and the sealing rod comprises coaxial upper segment and hypomere, and the necking down section comprises coaxial upper portion cavity radius bench section, middle cavity cylinder section and lower part cavity round bench section, and the hypomere of sealing rod and the middle cavity cylinder section interference fit of necking down section, its characterized in that, the whole hollow tube structure that is of sealing rod, the hypomere of sealing rod is cavity radius bench structure.
2. The platelet-rich plasma separation device of claim 1 wherein the upper section of the sealing rod is a hollow cylinder.
3. The platelet-rich plasma separation device according to claim 2, wherein the outer diameter of the upper section of the sealing rod is equal to the outer diameter of the large end of the lower section of the sealing rod, the wall thickness of the upper section of the sealing rod is t1, and the wall thickness of the lower section of the sealing rod is gradually reduced from t1 to 0 from top to bottom.
4. The platelet-rich plasma separation device according to claim 3, wherein the length of the upper section of the sealing rod is 58.3mm, and the outer diameter is 7.0 to 7.6 mm; the length of the lower section of the sealing rod is 2.5-5 mm, and the taper is 58-75 degrees; t1 is 1 mm.
5. The platelet-rich plasma separation device of claim 4 wherein the length of the middle hollow cylindrical section of the neck section is 8mm, the wall thickness is t2, the outer diameter is d, d is 7.0-7.6 mm, and t2 is 1 mm.
6. The platelet-rich plasma separation device according to claim 5 wherein the upper and lower hollow rounded off sections of the neck section have a wall thickness of t2 and the smaller end has an outer diameter of d; the length of the hollow inverted circular truncated cone section at the upper part of the neck-reducing section is 11.7mm, and the taper is 45 degrees; the length of the hollow circular platform section at the lower part of the necking section is 11.7mm, and the taper is 45 degrees.
7. The platelet-rich plasma separation device according to any one of claims 1 to 6, wherein the enrichment ratio of the platelet-rich plasma separation device is 86% or more, and the sealing property is good or excellent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210659716.7A CN114887681A (en) | 2022-06-13 | 2022-06-13 | Platelet-rich plasma separation device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210659716.7A CN114887681A (en) | 2022-06-13 | 2022-06-13 | Platelet-rich plasma separation device |
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| CN114887681A true CN114887681A (en) | 2022-08-12 |
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| CN202210659716.7A Pending CN114887681A (en) | 2022-06-13 | 2022-06-13 | Platelet-rich plasma separation device |
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| CN (1) | CN114887681A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100105355A (en) * | 2009-03-16 | 2010-09-29 | 문상호 | Fibrin forming method using platelet rich plasma clot |
| CN111013197A (en) * | 2019-12-31 | 2020-04-17 | 山东中保康医疗器具有限公司 | Disposable platelet-rich plasma separation device |
| CN215534415U (en) * | 2021-08-27 | 2022-01-18 | 新疆维吾尔自治区人民医院 | Vacuum blood collection tube for separating PRP |
| CN216573622U (en) * | 2022-01-11 | 2022-05-24 | 杭州博科迈生物科技有限公司 | Disposable separating device for platelet-rich plasma |
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2022
- 2022-06-13 CN CN202210659716.7A patent/CN114887681A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100105355A (en) * | 2009-03-16 | 2010-09-29 | 문상호 | Fibrin forming method using platelet rich plasma clot |
| CN111013197A (en) * | 2019-12-31 | 2020-04-17 | 山东中保康医疗器具有限公司 | Disposable platelet-rich plasma separation device |
| CN215534415U (en) * | 2021-08-27 | 2022-01-18 | 新疆维吾尔自治区人民医院 | Vacuum blood collection tube for separating PRP |
| CN216573622U (en) * | 2022-01-11 | 2022-05-24 | 杭州博科迈生物科技有限公司 | Disposable separating device for platelet-rich plasma |
Non-Patent Citations (1)
| Title |
|---|
| 刘巽尔: "互换性原理与测量技术基础", 中国广播电视大学出版社, pages: 172 * |
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