CN206315325U - Integrated autologous platelet rich plasma preparation suit - Google Patents
Integrated autologous platelet rich plasma preparation suit Download PDFInfo
- Publication number
- CN206315325U CN206315325U CN201620817174.1U CN201620817174U CN206315325U CN 206315325 U CN206315325 U CN 206315325U CN 201620817174 U CN201620817174 U CN 201620817174U CN 206315325 U CN206315325 U CN 206315325U
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- Prior art keywords
- prp
- tube
- sampling
- platelet rich
- rich plasma
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Abstract
The utility model is related to a kind of integrated autologous platelet rich gel preparation suit, including blood plasma storage tube, connecting tube and red blood cell storage tube closure, connecting tube is made up of successively the PRP storage tubes, locking pipe and red blood cell storage tube of one, blood plasma storage tube is threadedly coupled with PRP storage tubes, and red blood cell storage tube is threadedly coupled with red blood cell storage tube closure；Guiding tube is extracted provided with blood plasma and PRP extracts guiding tube in blood plasma storage tube, the length that PRP extracts guiding tube is more than the length that blood plasma extracts guiding tube, blood plasma is provided with the top of blood plasma storage tube and extracts mouth and PRP extraction mouths, blood plasma extracts mouth and is connected with blood plasma extraction guiding tube, and PRP extracts mouth and is connected with PRP extraction guiding tubes；Lock and block provided with red blood cell in locking pipe, perforate and the red blood cell locking blocking of blood plasma storage bottom of the tube match.The suit have the advantages that can to complete in integrated apparatus whole extraction process, it is simple and quick efficiently, be difficult pollution.
Description
Technical field
The utility model is related to a kind of rich platelet gel（Blood plasma）Extraction element, especially a kind of autologous rich blood of integration
Platelet-poor plasma preparation is set with, and belongs to medical instruments field.
Background technology
Platelet rich plasma（Platelet Rich Plasma, abbreviation PRP）, it is that autologous whole blood passes through obtained from centrifugation
Containing the hematoblastic blood plasma of high concentration.Contain substantial amounts of growth factor, such as blood platelet in blood platelet containing high concentration in PRP, blood platelet
Derivative growth factor（PDGF）, transforming growth factor-β (TGF-β), IGF（IGF）, EGF
（EGF）, VEGF（VEGF）, fibroblast growth factor（FGF）Deng, these growth factors can accurately from
I navigates to damage location, controls inflammation, and never Tongfang plays facilitation in face of cell and regeneration, so as to accelerate damage
The repair of tissue, high degree mitigates the formation of scar after the operation.Further, since PRP can be carried from patient's self-blood
Take, after extracted enrichment processing, available for the treatment of relevant disease, thus abundance, convenient material drawing, preparation method it is simple and
And body can be allowed to absorb, itself PRP occurs using the problem of being also avoided that viral transmission and immunological rejection, therefore PRP is wide
It is general to be applied to various surgical operations, openheart surgery and plastic operation, creeped for postoperative provided for repair cell of surgical operation
Support and growth factor, promote bone tissue regeneration, accelerate soft tissue repair and wound healing, mitigate wound pain；For chronic
Skin ulcer, accelerates skin growth, reduces infection chance；Also in terms of being widely used in medical cosmetology, it is more evenly distributed, smoothing wrinkle effect
Fruit is more rapidly, persistently.So PRP extraction quality is to influence the key factor of its function and effect.
PRP is under household condition to prepare in operating room, but must keep sterile in centrifugal process, and need to be
Do not have to separate under the high concentration of thrombocytolysis or destruction, PRP results prepared by different PRP instrument are different, its preparation principle master
If different using various composition sinking speed in blood, blood is layered by centrifugation, so that obtain containing hematoblastic blood plasma,
And further concentrate to obtain the thrombocyte plasma of high concentration using centrifugation.At present a whole set of is used during separation and Extraction
The device being made up of parts such as some test tubes, syringes, need to be by multiple injection, centrifugation, extraction, and operation is relative complex, and if
Dry part is separated and used successively, easily causes pollution.And due to the otherness of blood sample, existing separator is difficult to
Effectively platelet rich plasma layer is collected.
The content of the invention
Technical problem to be solved in the utility model is to provide one kind can complete in an integral structure device
Whole platelet rich plasma extraction process, sample provided with different height PRP region, it is simple and quick efficiently, be difficult the one of pollution
Change autologous platelet rich plasma preparation suit.
The utility model solves above-mentioned used technical scheme：The suit includes outer tube and inner tube, and inner tube is placed in outer
In pipe, and outer tube wall is brought into close contact with outer wall of inner tube, and it, which is structurally characterized in that in said inner tube, is provided with one section by some annulars
The PRP collecting regions of groove composition.
Inner tube described in the utility model is longitudinally provided with some PRP thief holes on the tube wall of its PRP collecting region, and outer tube is at it
The tube wall position corresponding with PRP thief holes is provided with some PRP sampling windows, and PRP sampling windows are connected with PRP thief holes,
Seal is provided with each PRP thief holes and PRP sampling windows.
PRP sampling plugs are installed, PRP samplings are provided with beyond the Great Wall to be taken with PRP at the PRP sampling windows of outer tube described in the utility model
The corresponding some PRP sample taps of sample window, PRP sample taps are connected with PRP sampling windows, PRP thief holes, and seal is to each PRP
Sample tap, PRP sampling windows and PRP thief holes are sealed.
Annular groove described in the utility model arrangement parallel to each other, and the distance between each adjacent annular groove is identical.
The distance between each adjacent PRP thief holes described in the utility model are identical.
Sealing-plug is provided with the opening of inner tube described in the utility model, sealing-plug, which is provided with, to be used to connect adopting for blood taking needle
PPP is additionally provided with blood plug, sealing-plug and extracts mouth and PRP extraction mouths, PPP extracts mouth and is connected with PPP sampling probes, PPP samplings
The syringe needle position of pin is located at the top of PRP collecting regions, and PRP extracts mouth and is connected with PRP sampling probes, the needle section of PRP sampling probes
Position is stretched into PRP collecting regions.
Outer wall at interior tube opening described in the utility model is provided with the locating piece of evagination, outer tube opening and is provided with and positioning
The locating slot for the indent that block matches, locating piece is located in locating slot.
The utility model is provided with closure at the opening of outer tube, and closure is by the base and top cover group that interconnect
Into the inner side of top cover is provided with the sealing column of evagination, and sealing column is located above blood sampling plug.
Seal described in the utility model is rubber plug.
The utility model compared with prior art, has the advantages that：1st, because individual has differences, everyone
Packed cell volume is different, in conjunction with different centrifugal speed and centrifugation time, the rich platelet blood isolated from blood samples of patients
Liquid level of the pulp layer in centrifugal separating tube is also just different, and this is sleeved on the PRP samplings that PRP collecting regions are designed with different height
Region, the pre-buried PRP sampling probes also in PRP collecting regions can be received according to the liquid level of platelet rich plasma layer from PRP
Ji Qu different directions and height extract platelet rich plasma layer, can meet different packed cell volume patients, different centrifugation speed
The demand of degree and centrifugation time, enough valid density can be extracted with the platelet rich plasma layer for ensureing different liquid levels
Platelet rich plasma, reduce the operation difficulty of operating personnel, improve the collection efficiency of platelet rich plasma；2nd, the suit
Inner tube use negative pressure of vacuum, with same separating pipe can complete gather blood, separation PRP, gather PRP overall process, behaviour
It is easy to make, and closed collection is convenient, without uncapping, non-secondary pollution, it is ensured that nontoxic, sterile, without personnel；3rd, the inner tube of the suit
Inside it is embedded with PPP（Platelet Poor Plasma, abbreviation PPP）Sampling probe, it is ensured that the superiors after separation can be drawn and contained
A small amount of hematoblastic plasma layer；4th, the PRP collecting regions of the suit are made up of some annular grooves, and the design of annular groove can be protected
Card platelet rich plasma layer is isolated and is enriched in PRP collecting regions as far as possible with red blood cell layer, prevents the red blood cell layer of sedimentation
Platelet rich plasma layer is mixed into, is conducive to improving the concentration of thrombocyte plasma layer.
Brief description of the drawings
Fig. 1 is front view of the present utility model.
Fig. 2 is left view of the present utility model.
Fig. 3 is right view of the present utility model.
Fig. 4 is stereogram of the present utility model.
Fig. 5 is the front view of the utility model middle external tube.
Fig. 6 is the left view of the utility model middle external tube.
Fig. 7 is the right view of the utility model middle external tube.
Fig. 8 is Fig. 5 profile.
Fig. 9 is the stereogram of the utility model middle external tube.
Figure 10 is the front view of inner tube in the utility model.
Figure 11 is the left view of inner tube in the utility model.
Figure 12 is the stereogram of inner tube in the utility model.
Figure 13 is the structural representation after closure opening in the utility model.
Figure 14 is the front view of sealing-plug in the utility model.
Figure 15 is the top view of sealing-plug in the utility model.
Figure 16 is the upward view of sealing-plug in the utility model.
Figure 17 is the stereogram of sealing-plug in the utility model.
Figure 18 is the stereogram of seal washer in the utility model.
Figure 19 is the front view of PRP sampling plugs in the utility model.After Figure 20 is PRP samplings plug in the utility model
View.
Figure 21 is the right view of PRP sampling plugs in the utility model.
Figure 22 is the stereogram of PRP sampling plugs in the utility model.
Figure 23 is the front view of seal plug in the utility model.
Figure 24 is the stereogram of seal plug in the utility model.
Figure 25 is Fig. 1 A-A sectional views.
Figure 26 is labeled with the schematic diagram of containing mark for Figure 25 outer tube outer surface.
Figure 27 is Fig. 2 B-B sectional views.
Figure 28 is enlarged drawing at Figure 26 C.
Figure 29 is Figure 27 stereogram.
Figure 30 is enlarged drawing at Figure 29 D.
Figure 31 is stereogram when Figure 27 opens closure.
Embodiment
Referring to Fig. 1-Figure 31, the present embodiment includes outer tube 1 and inner tube 2, and inner tube 2 is placed in outer tube 1, and the inwall of outer tube 1 with
The outer wall of inner tube 2 is brought into close contact.Outer tube 1 and the design specification of inner tube 2 are 50ml, and corresponding appearance is labeled with the outer surface of outer tube 1
Scale is measured, bar code or Quick Response Code, label area is also provided with, label area form is：UUID/ Code of the production places/production batch
Secondary/production numbering/reserved place/reserved place/reserved place.The material of outer tube 1 be polypropylene, polyethylene or polyvinylidene fluoride, it is interior
The material of pipe 2 is polypropylene or polyethylene.
It is provided with inner tube 2 in one section of PRP collecting region 4 being made up of some annular grooves 3, the present embodiment, annular is recessed
The quantity of groove 3 is five.Each arrangement parallel to each other of annular groove 3, and the distance between each adjacent annular groove 3 is identical.PRP is received
Collect and four PRP thief holes 11 are longitudinally provided with the tube wall in area 4, the distance between each adjacent PRP thief holes 11 are identical.Outer tube 1 exists
Its tube wall position corresponding with PRP thief holes 11 is provided with four PRP sampling windows 12, PRP sampling windows 12 and PRP thief holes 11
Size it is identical and be connected.PRP sampling plug 14, PRP sampling plugs 14 are installed at PRP sampling windows 12 provided with being taken with PRP
Four corresponding PRP sample taps 15 of sample window 12, PRP sample taps 15 are connected with PRP sampling windows 12, PRP thief holes 11.Four
Seal 13 is respectively placed in four PRP sample taps 15, PRP sampling windows 12 and PRP thief holes 11, to PRP sample taps 15, PRP
Sampling window 12 and PRP thief holes 11 are sealed, and seal 13 is halogenated butyl rubber plug in the present embodiment.
Sealing-plug 5 is provided with the opening of inner tube 2, sealing-plug 5 is halogenated butyl rubber plug.Sealing-plug 5 is provided with indent
Be used to connect and be additionally provided with that PPP extracts mouth 7 and PRP extracts mouth 8 on the blood sampling plug 6 of blood taking needle, sealing-plug 5, PPP extracts mouth 7
It is connected with PPP sampling probes 9, the syringe needle position of PPP sampling probes 9 is located at the top of PRP collecting regions 4, PRP extracts mouth 8 and PRP and taken
Sample pin 10 is connected, and the syringe needle position of PRP sampling probes 10 is stretched into PRP collecting regions 4.And PPP extracts mouth 7 and PRP extracts mouth 8 and used
Aluminium plastic membrane is sealed.
Closure 17 is provided with the opening of outer tube 1, closure 17 is made up of the base 18 and top cover 19 interconnected,
Seal washer 22 is installed between base 18 and top cover 19.Base 18 is connected with outer tube 1, and the inner side of top cover 19 is provided with evagination
Sealing column 20, when top cover 19 closes, sealing column 20 is located at blood sampling plug 6 top.
Outer wall at the opening of inner tube 2 is provided with four locating pieces 16 for being circumferentially uniformly distributed simultaneously evagination, the opening of outer tube 1
Locating slot 21 provided with the indent matched with locating piece 16, when inner tube 2 is placed in outer tube 1, locating piece 16 is located at locating slot 21
It is interior.When inner tube 2 is put into outer tube 1, such design can avoid the PRP on PRP sampling windows 12 and inner tube 2 on outer tube 1 from taking
Sample hole 11 misplaces, to ensure that PRP thief holes 11 are located at the position corresponding with PRP sampling windows 12.
In addition, presetting anti-coagulants in the bottom of inner tube 2（Sodium citrate anticoagulant, ACD buffer solutions）Or anti-coagulants adds
Separation gel；Covered again with sealing-plug 5 after being evacuated in inner tube 2 seals it at the opening of inner tube 2, negative for vacuum in inner tube 2
Pressure condition.Sealing-plug 5, the material of seal plug 13 are halogenated butyl rubber.
Outer tube 1 and inner tube 2 can be designed as 25ml equal-specifications as needed.
The application method of the present embodiment is as follows：
1st, the top cover 19 of closure 17 is opened, the blood sampling on the needle pierces sealing-plug 5 of disposable blood taking needle one end is blocked up
In first 6, extraction Venous Blood 50ml to inner tube 2, then top cover 19 swings back and forth and rocks centrifugal separating tube, makes inner tube 2
Interior preset anti-coagulants is sufficiently mixed with blood；
2nd, centrifugal separating tube is put into centrifuge, the blood after centrifugation is divided into three layers, and orlop is that sedimentation coefficient is maximum
Red blood cell layer, the superiors are containing a small amount of hematoblastic plasma layer（PPP）, both intersections are platelet rich plasma layer（PRP）, most
The red blood cell layer of lower floor is all located at the lower section of PRP collecting regions 4 substantially, and the plasma layer of the superiors is all located at PRP collecting regions 4 substantially
Top, a small amount of plasma layer is located at the top of PRP collecting regions 4；The amount of general platelet rich plasma layer is controlled in total blood sampling volume
About 1/10, therefore platelet rich plasma layer total amount is in 5ml of red blood cell layer ullage or so；
3rd, the top cover 19 of closure 17 is opened, the PPP on the needle pierces sealing-plug 5 of a 10ml asepsis injector is carried
Mouth 7 is taken, reserved PRP amounts, extract PPP plasma layers as needed；
4th, due to everyone individual difference, packed cell volume is different, in conjunction with different centrifugal speed and centrifugation time,
Liquid level of the platelet rich plasma layer isolated from blood samples of patients in PRP collecting regions 4 is also just different, the centrifugation
Lateral layout of the pipe in PRP acquisition zones 4 has the PRP sample taps 15, PRP sampling windows 12 and PRP thief holes 11 of four different heights,
The PRP samplings region of four different heights is constituted, can now be extracted as needed from the different directions of PRP collecting regions and position
Go out platelet rich plasma layer（PRP）；PRP on the needle pierces sealing-plug 5 of one 5ml asepsis injector is extracted into mouth 8, extracted
Go out platelet rich plasma, can be small according to rich blood if platelet rich plasma layer is not in the needle position of pre-buried PRP sampling probes 10
Liquid level of the plate plasma layer in PRP collecting regions 4, selects the PRP samplings region that its liquid level is corresponding, removes the PRP
The seal 13 in region is sampled, the syringe needle of 5ml asepsis injectors is passed through PRP sample taps 15, PRP by sterilization PRP sample taps 15
Sampling window 12, PRP thief holes 11 are stretched into PRP collecting regions 4, extract platelet rich plasma；
5th, PRP is activated：Before 5ml asepsis injectors pierce through and collect PRP, 0.1ml activation liquid can be first extracted（Chlorination
Calcium）Syringe inner tubal wall is moistened, unnecessary activation liquid is then outwards discarded；PRP gels can be prepared into after PRP addition activator；
It is different according to purposes, activator can also be not added with.
The integrated autologous platelet rich plasma preparation suit can be also used for the separation of candidate stem cell.
It is the implementation example of this patent above, but the protection domain of this patent is not limited to the embodiment, and this area is common
The change that technical staff makes in the range of claim restriction, should be included in the protection domain of this patent.
Claims (9)
1. a kind of integrated autologous platelet rich plasma preparation suit, including outer tube（1）And inner tube（2）, inner tube（2）It is placed in outer
Pipe（1）It is interior, and outer tube（1）Inwall and inner tube（2）Outer wall is brought into close contact, it is characterized in that：Said inner tube（2）On be provided with one section by
Some annular grooves（3）The PRP collecting regions of composition（4）.
2. integrated autologous platelet rich plasma preparation suit according to claim 1, it is characterized in that：Said inner tube
（2）In its PRP collecting region（4）Tube wall on longitudinally be provided with some PRP thief holes（11）, outer tube（1）Sampled in its tube wall and PRP
Hole（11）Corresponding position is provided with some PRP sampling windows（12）, PRP sampling windows（12）With PRP thief holes（11）It is connected,
In each PRP thief holes（11）With PRP sampling windows（12）Place is provided with seal（13）.
3. integrated autologous platelet rich plasma preparation suit according to claim 2, it is characterized in that：The outer tube
（1）PRP sampling windows（12）Place is provided with PRP sampling plugs（14）, PRP sampling plugs（14）It is provided with and PRP sampling windows（12）Phase
Corresponding some PRP sample taps（15）, PRP sample taps（15）With PRP sampling windows（12）, PRP thief holes（11）It is connected, seals
Part（13）To each PRP sample taps（15）, PRP sampling windows（12）With PRP thief holes（11）Sealed.
4. integrated autologous platelet rich plasma preparation suit according to claim 1, it is characterized in that：Described annular
Groove（3）Arrangement parallel to each other, and each adjacent annular groove（3）The distance between it is identical.
5. integrated autologous platelet rich plasma preparation suit according to claim 2, it is characterized in that：It is described each adjacent
PRP thief holes（11）The distance between it is identical.
6. integrated autologous platelet rich plasma preparation suit according to claim 1, it is characterized in that：Said inner tube
（2）Opening at be provided with sealing-plug（5）, sealing-plug（5）It is provided with the blood sampling plug for being used for connecting blood taking needle（6）, sealing-plug
（5）On be additionally provided with PPP extract mouth（7）Mouth is extracted with PRP（8）, PPP extraction mouths（7）With PPP sampling probes（9）It is connected, PPP takes
Sample pin（9）Syringe needle position be located at PRP collecting regions（4）Top, PRP extract mouth（8）With PRP sampling probes（10）It is connected, PRP
Sampling probe（10）Syringe needle position stretch into PRP collecting regions（4）In.
7. integrated autologous platelet rich plasma preparation suit according to claim 1, it is characterized in that：Said inner tube
（2）Outer wall at opening is provided with the locating piece of evagination（16）, outer tube（1）It is provided with opening and locating piece（16）What is matched is interior
Recessed locating slot（21）, locating piece（16）Positioned at locating slot（21）It is interior.
8. integrated autologous platelet rich plasma preparation suit according to claim 1, it is characterized in that：In outer tube（1）
Opening at be provided with closure（17）, closure（17）By the base interconnected（18）And top cover（19）Composition, top cover
（19）Inner side be provided with evagination sealing column（20）, sealing column（20）Positioned at blood sampling plug（6）Top.
9. integrated autologous platelet rich plasma preparation suit according to claim 2, it is characterized in that：The seal
（13）For rubber plug.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620817174.1U CN206315325U (en) | 2016-08-01 | 2016-08-01 | Integrated autologous platelet rich plasma preparation suit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620817174.1U CN206315325U (en) | 2016-08-01 | 2016-08-01 | Integrated autologous platelet rich plasma preparation suit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206315325U true CN206315325U (en) | 2017-07-11 |
Family
ID=59262713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620817174.1U Expired - Fee Related CN206315325U (en) | 2016-08-01 | 2016-08-01 | Integrated autologous platelet rich plasma preparation suit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206315325U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106139290A (en) * | 2016-08-01 | 2016-11-23 | 娄域峰 | Integration autologous platelet rich plasma preparation suit |
| WO2019236039A3 (en) * | 2018-03-02 | 2020-01-30 | Ince Bilsev | A sterile prp tube |
-
2016
- 2016-08-01 CN CN201620817174.1U patent/CN206315325U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106139290A (en) * | 2016-08-01 | 2016-11-23 | 娄域峰 | Integration autologous platelet rich plasma preparation suit |
| WO2019236039A3 (en) * | 2018-03-02 | 2020-01-30 | Ince Bilsev | A sterile prp tube |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170711 Termination date: 20190801 |
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| CF01 | Termination of patent right due to non-payment of annual fee |