CN106310720A - Platelet rich plasma separator - Google Patents

Platelet rich plasma separator Download PDF

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Publication number
CN106310720A
CN106310720A CN201610946541.2A CN201610946541A CN106310720A CN 106310720 A CN106310720 A CN 106310720A CN 201610946541 A CN201610946541 A CN 201610946541A CN 106310720 A CN106310720 A CN 106310720A
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CN
China
Prior art keywords
prp
storeroom
blood plasma
separator
platelet rich
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610946541.2A
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Chinese (zh)
Inventor
程欢
王友爱
张家铭
李薇
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Jiangsu Weiss Biological Medical Technology Co Ltd
Original Assignee
Jiangsu Weiss Biological Medical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Weiss Biological Medical Technology Co Ltd filed Critical Jiangsu Weiss Biological Medical Technology Co Ltd
Priority to CN201610946541.2A priority Critical patent/CN106310720A/en
Publication of CN106310720A publication Critical patent/CN106310720A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D17/00Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02Separation of non-miscible liquids
    • B01D17/0217Separation of non-miscible liquids by centrifugal force

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  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a platelet rich plasma separator. The separator is wholly of cylindrical shape. The platelet rich plasma separator structurally comprises a PRP (Platelet Rich Plasma) storage cover, a puncture silica gel plug, a PRP storage cover moveable plug, a PRP storage, a one-way spinning valve-b, a plasma storage upper end, a plasma storage lower end, a one-way spinning valve-a, an erythrocyte storage and an erythrocyte storage cover from top to bottom. In a use process, the extracted autologous blood is injected into the separator; PRP is separated and extracted in the manner of closed twice centrifuging; the one-way spinning valve is designed at a joint of the PRP storage and the plasma storage upper end; the medical care operation is simplified; the PRP extracting time is shortened; the PRP storage is designed in a funnel form, so that the medical care personnel is convenient to separate and extract PRP.

Description

A kind of platelet rich plasma separator
Technical field
The invention belongs to medical instruments field, particularly to a kind of platelet rich plasma separator.
Background technology
PRP (Platelet Rich Plasma) refers to rich in platelet, blood plasma or the blood rich in somatomedin.PRP Extractive technique refers to utilize the blood of self, extracts rich in high concentration platelet and the blood plasma of the various own growth factor.PRP Autoserum has a following advantage:
1.PRP there are multiple somatomedin, the ratio of each somatomedin are consistent with internal normal rates, make to have between somatomedin Optimal synergism, this compensate for the shortcoming that single factors stimulated growth wound repair is the best to a certain extent.
2. the damage of couple patient is little and makes simple, can effectively reduce medical treatment cost, promote the wound healing of patient.
3.PRP contains a large amount of fibrin, provides good support for repair cell, it is also possible to shrinks wound surface, has rush The effect of blood coagulation, can stimulate soft tissue regeneration, promotes wound early secondary closure and prevents from infecting.
4. it is close with platelet sedimentation coefficient in blood due to leukocyte and mononuclear cell, so method makes by centrifugation PRP in possibly together with larger amount of leukocyte and mononuclear cell, this can preferably play the effect preventing infecting.
5.PRP can be frozen into glue with thrombin, is possible not only at adhesion organization's defect, it is also possible to prevent hematoblastic stream Lose, make platelet secrete somatomedin for a long time in local, keep higher somatomedin concentration, it is to avoid be widely used in facing The liquid recombinant growth factors reagent of bed is easy to run off evaporable shortcoming at wound.
Although PRP is applied to multiple fields such as orthopaedics, plastic surgery, dentistry, wound healing, but there is no at present specially Door prepares the equipment listing of PRP, mostly uses open secondary centrifuging method to prepare PRP, and the following shortcoming existed greatly limits Make it in clinical application: be easily subject to outside contamination, multiple containers shift, adds platelet activation and contaminated machine Meeting;Recovery rate of blood platelet is relatively low;Easily being affected by operation factors, preparation method is not sufficiently stable;Do not have special to answer recruitment Tool, in-convenience in use.Currently also there is minority to use enclosed secondary centrifuging method to prepare PRP, but still suffer from following shortcoming: doctor Protect human users's step complicated, time-consumingly, and can not be accurately separated, extract PRP.
Summary of the invention
Above not enough for solving, the present invention provides a kind of platelet rich plasma separator, uses closed secondary centrifuging Mode can conveniently isolate the PRP in blood;Separator punctures silica gel plug and PRP storage chamber cap motion stops and PRP storage Chamber cap motion stops stores the connected mode good sealing effect of chamber cap with PRP, it is possible to the size of regulation PRP storeroom;Store up at PRP Hide the design of room and blood plasma storeroom upper end employing single-pass stopcock, simplify medical care operation, shorten PRP extraction time;PRP storeroom Use flared design, it is simple to medical personnel are accurately separated and extract PRP;The position of blood plasma inlet is arranged is easy to medical care Human users.
The technical solution adopted in the present invention is:
A kind of platelet rich plasma separator, overall in cylinder, structure includes PRP storage chamber cap from top to bottom, punctures silica gel Plug, PRP store chamber cap motion stops, PRP storeroom, single-pass stopcock-b, blood plasma storeroom upper end, blood plasma storeroom lower end, single-pass Stopcock-a, erythrocyte storeroom and erythrocyte storage chamber cap.
Described PRP storeroom, blood plasma storeroom upper end are funneling with blood plasma storeroom lower end and erythrocyte storeroom Structure, the PRP storeroom of funnel structure design is easy to medical personnel and is accurately separated and extracts PRP.
Described PRP storage chamber cap is threaded connection with PRP storeroom, is provided with sealing ring-c in threaded connection place, Sealing ring can withstand the screw socket of PRP storage chamber cap and effectively seal to be formed;
It is provided with puncture silica gel plug in described PRP storage chamber cap and PRP stores chamber cap motion stops, puncture silica gel plug one end and have Cylindrical protrusions, can fill in the hole of PRP storage chamber cap motion stops, be formed and seal structure;And set on silica gel plug puncturing It is equipped with PRP and extracts mouth, extract mouth by PRP after centrifugation and extract PRP.
Described PRP storage chamber cap is connected with PRP storage chamber cap motion stops by buckle.Chamber cap is stored by degree of tightness PRP The size of place's screw thread scalable PRP storeroom.
Described single-pass stopcock-b is arranged at the intermediate connections of PRP storeroom and blood plasma storeroom upper end, is revolved by single-pass After valve-b 90-degree rotation, PRP storeroom can be closed PRP is locked in PRP storeroom;On PRP storeroom and blood plasma storeroom End is integral type structure.The setting of single-pass stopcock-b is easy to separate operation during PRP, can shorten extraction time.
Described blood plasma storeroom upper end prism is provided with ventilation mouth & and punctures silicon rubber cup and blood plasma inlet, ventilation mouth & Puncture silicon rubber cup and be built-in with ventilation mouth, ventilated membrane and rubber cushion, puncture silicon rubber cup in order to seal ventilation mouth &;Open ventilation mouth & to puncture After silicon rubber cup, then inject blood plasma from blood plasma inlet, close ventilation mouth & after injection and puncture silicon rubber cup.Blood plasma inlet Position is arranged, it is simple to medical personnel operate.
Described blood plasma storeroom upper end and blood plasma storeroom lower end are threaded connection, junction be provided with sealing ring- b。
Described single-pass stopcock-a is arranged at the intermediate connections of blood plasma storeroom lower end and erythrocyte storeroom, by single-pass After stopcock-a 90-degree rotation, erythrocyte storeroom can be closed erythrocyte is locked in erythrocyte storeroom;Under blood plasma storeroom End and erythrocyte storeroom are integral type structure.
Described blood plasma storeroom lower end is threaded connection with erythrocyte storage chamber cap, and threaded connection place is provided with sealing Circle-a.
The invention has the beneficial effects as follows:
1, closed secondary centrifuging, reduces platelet activation and contaminated chance.
2, PRP preparation time is shorter, reduces the damage of composition in blood.
3, simplify medical care operation, shorten PRP extraction time.
4, it is easy to medical personnel be accurately separated and extract PRP.
Accompanying drawing explanation
Fig. 1 is the STRUCTURE DECOMPOSITION schematic diagram of separator of the present invention.
Fig. 2 is the schematic appearance of separator of the present invention.
Fig. 3 is the profile of the line A-A along Fig. 2.
Fig. 4 is the partial enlarged drawing of Fig. 3.
In figure 1, PRP store chamber cap, 2, PRP extract mouth, 3, puncture silica gel plug, 4, PRP store chamber cap motion stops, 5, sealing Circle-c, 6, PRP storeroom, 7, single-pass stopcock-b, 8, single-pass stopcock-a, 9, ventilated membrane, 10, rubber cushion, 11, ventilation mouth & puncture silicon Capsule, 12, ventilation mouth, 13, blood plasma inlet, 14, sealing ring-b, 15, blood plasma storeroom upper end, 16, blood plasma storeroom lower end, 17, erythrocyte storeroom, 18, sealing ring-a, 19, erythrocyte storage chamber cap.
Detailed description of the invention
Below in conjunction with the accompanying drawings, technical scheme is described in detail.
Platelet rich plasma cyclone separator arrangement of the present invention includes PRP storage chamber cap 1 from top to bottom, punctures silica gel plug 3, PRP Storage chamber cap motion stops 4, PRP storeroom 6, single-pass stopcock-b7, blood plasma storeroom upper end 16, blood plasma storeroom lower end 17, single-pass Stopcock-a8, erythrocyte storeroom 17 and erythrocyte storage chamber cap 19.
Described PRP storeroom, blood plasma storeroom upper end, blood plasma storeroom lower end and erythrocyte storeroom are funneling knot Structure, the PRP storeroom of funnel structure design is easy to medical personnel and is accurately separated and extracts PRP.
Described PRP storage chamber cap is threaded connection with PRP storeroom, is provided with sealing ring-c in threaded connection place, Sealing ring can withstand the screw socket of PRP storage chamber cap and effectively seal to be formed;
It is provided with puncture silica gel plug 3 and PRP in described PRP storage chamber cap and stores chamber cap motion stops 4, puncture silica gel plug one end tool There is cylindrical protrusions, can fill in the hole of PRP storage chamber cap motion stops, be formed and seal structure;And puncturing on silica gel plug It is provided with PRP and extracts mouth 2, extract mouth by PRP after centrifugation and extract PRP.
Described PRP storage chamber cap is connected with PRP storage chamber cap motion stops by buckle.Chamber cap is stored by degree of tightness PRP The size of place's screw thread scalable PRP storeroom.
Described single-pass stopcock-b7 is arranged at the intermediate connections of PRP storeroom and blood plasma storeroom upper end, is revolved by single-pass After valve-b 90-degree rotation, PRP storeroom can be closed PRP is locked in PRP storeroom;On PRP storeroom and blood plasma storeroom End is integral type structure.The setting of single-pass stopcock-b is easy to separate operation during PRP, can shorten extraction time.
Described blood plasma storeroom upper end prism is provided with ventilation mouth & and punctures silicon rubber cup 11 and blood plasma inlet 13, thoroughly QI KOU & punctures silicon rubber cup and is built-in with ventilation mouth 12, ventilated membrane 9 and rubber cushion 10, punctures silicon rubber cup in order to seal ventilation mouth &, opens After ventilation mouth & punctures silicon rubber cup, then inject blood plasma from blood plasma inlet, close ventilation mouth & after injection and puncture silicon rubber cup.Blood The position of slurry inlet is arranged, it is simple to medical personnel operate.
Described blood plasma storeroom upper end and blood plasma storeroom lower end be threaded connection junction be provided with sealing ring- b14。
Described single-pass stopcock-a8 is arranged at the intermediate connections of blood plasma storeroom lower end and erythrocyte storeroom 17, will After single-pass stopcock-a 90-degree rotation, erythrocyte storeroom can be closed erythrocyte is locked in erythrocyte storeroom;Blood plasma is stored Lower end, room and erythrocyte storeroom are integral type structure.
Described blood plasma storeroom lower end is threaded connection with erythrocyte storage chamber cap 19, and threaded connection place is provided with close Seal-a18.
Separator of the present invention is utilized to prepare plateletrich method as follows:
A, extraction autoblood, open ventilation mouth and puncture silicon rubber cup, from blood plasma inlet, blood is injected blood, has injected blood Close ventilation mouth & after liquid and puncture silicon rubber cup.
B, erythrocyte Storage is put into centrifuge down separating for the first time, after separation, upper strata is serum, lower floor be red carefully Born of the same parents.
C, adjustment erythrocyte storage chamber cap make erythrocyte to interface, and single-pass stopcock-a 90-degree rotation is closed erythrocyte storage Room, puts into centrifuge down by PRP Storage and carries out secondary centrifuging.
D, adjustment PRP storage chamber cap make PRP to zero interface, and single-pass stopcock-b 90-degree rotation is closed PRP storeroom.
E, finally use syringe extract mouth from PRP and extract PRP.
The above, the only detailed description of the invention of the present invention, but protection scope of the present invention is not limited thereto, and any Those of ordinary skill in the art in the technical scope that disclosed herein, the change that can readily occur in or replacement, all should contain Cover within protection scope of the present invention.Therefore, the protection model that protection scope of the present invention should be limited with claims Enclose and be as the criterion.

Claims (7)

1. a platelet rich plasma separator, it is characterised in that: separator is overall in cylinder, and structure includes from top to bottom PRP storage chamber cap, puncture silica gel plug, PRP storage chamber cap motion stops, PRP storeroom, single-pass stopcock-b, blood plasma storeroom upper end, Blood plasma storeroom lower end, single-pass stopcock-a, erythrocyte storeroom and erythrocyte storage chamber cap.
2. platelet rich plasma separator as claimed in claim 1, it is characterised in that: on PRP storeroom, blood plasma storeroom End, blood plasma storeroom lower end and erythrocyte storeroom are all in funnel structure.
3. the platelet rich plasma separator as described in claim 1,2, it is characterised in that: described single-pass stopcock-b is arranged at PRP storeroom and the intermediate connections of blood plasma storeroom upper end, PRP storeroom and blood plasma storeroom upper end are integral type structure; Described single-pass stopcock-a is arranged at the intermediate connections of blood plasma storeroom lower end and erythrocyte storeroom, blood plasma storeroom lower end It is integral type structure with erythrocyte storeroom.
4. platelet rich plasma separator as claimed in claim 3, it is characterised in that: arrange in described PRP storage chamber cap There are puncture silica gel plug and PRP to store chamber cap motion stops, puncture silica gel plug one end and there is cylindrical protrusions, PRP storeroom can be filled in In the hole of lid motion stops, formed and seal structure.
5. platelet rich plasma separator as claimed in claim 4, it is characterised in that: described PRP storage chamber cap is by card Detain and be connected with PRP storage chamber cap motion stops.
6. platelet rich plasma separator as claimed in claim 1, it is characterised in that: blood plasma storeroom upper end prism is arranged Ventilation mouth & is had to puncture silicon rubber cup and blood plasma inlet.
7. platelet rich plasma separator as claimed in claim 1, it is characterised in that: described blood plasma storeroom upper end and blood Slurry storeroom lower end is threaded connection, and junction is provided with sealing ring-b.
CN201610946541.2A 2016-10-26 2016-10-26 Platelet rich plasma separator Pending CN106310720A (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201610946541.2A CN106310720A (en) 2016-10-26 2016-10-26 Platelet rich plasma separator

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893884A (en) * 2019-03-19 2019-06-18 傅兰轲 A kind of PRP separation collector and its application method
CN110639712A (en) * 2019-10-11 2020-01-03 武汉济源高科技有限公司 Autologous platelet-rich plasma separation preparation device
CN114534312A (en) * 2022-01-12 2022-05-27 北京市美嘉亿盛医疗器械股份有限公司 PRP separator
CN115445683A (en) * 2022-09-24 2022-12-09 北京市美嘉亿盛医疗器械股份有限公司 PRP test tube
CN117563277A (en) * 2024-01-17 2024-02-20 北京瑞朗泰科医疗器械有限公司 Preparation device and method for separating platelet-rich plasma from blood

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202860184U (en) * 2012-09-11 2013-04-10 天津美德太平洋科技有限公司 Separator for PRP (Platelet Rich Rlasma) in blood
KR20130123727A (en) * 2012-05-03 2013-11-13 이은혜 Seperator and collection apparatus for extracting of platelet rich plasma
CN203648142U (en) * 2013-11-04 2014-06-18 常州尚泰医疗科技有限公司 Blood platelet-rich separation and extraction device
CN205340229U (en) * 2016-02-02 2016-06-29 张兴琳 PRP extraction element
CN206334402U (en) * 2016-10-26 2017-07-18 江苏维斯顿生物医疗科技有限公司 A kind of platelet rich plasma separator

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130123727A (en) * 2012-05-03 2013-11-13 이은혜 Seperator and collection apparatus for extracting of platelet rich plasma
CN202860184U (en) * 2012-09-11 2013-04-10 天津美德太平洋科技有限公司 Separator for PRP (Platelet Rich Rlasma) in blood
CN203648142U (en) * 2013-11-04 2014-06-18 常州尚泰医疗科技有限公司 Blood platelet-rich separation and extraction device
CN205340229U (en) * 2016-02-02 2016-06-29 张兴琳 PRP extraction element
CN206334402U (en) * 2016-10-26 2017-07-18 江苏维斯顿生物医疗科技有限公司 A kind of platelet rich plasma separator

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893884A (en) * 2019-03-19 2019-06-18 傅兰轲 A kind of PRP separation collector and its application method
CN110639712A (en) * 2019-10-11 2020-01-03 武汉济源高科技有限公司 Autologous platelet-rich plasma separation preparation device
CN114534312A (en) * 2022-01-12 2022-05-27 北京市美嘉亿盛医疗器械股份有限公司 PRP separator
CN114534312B (en) * 2022-01-12 2022-09-06 北京市美嘉亿盛医疗器械股份有限公司 PRP separator
CN115445683A (en) * 2022-09-24 2022-12-09 北京市美嘉亿盛医疗器械股份有限公司 PRP test tube
CN115445683B (en) * 2022-09-24 2023-08-22 北京市美嘉亿盛医疗器械股份有限公司 PRP test tube
CN117563277A (en) * 2024-01-17 2024-02-20 北京瑞朗泰科医疗器械有限公司 Preparation device and method for separating platelet-rich plasma from blood
CN117563277B (en) * 2024-01-17 2024-04-09 北京瑞朗泰科医疗器械有限公司 Preparation device and method for separating platelet-rich plasma from blood

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Application publication date: 20170111