CN209772422U - Integrated regeneration factor separation and enrichment preparation device - Google Patents
Integrated regeneration factor separation and enrichment preparation device Download PDFInfo
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- CN209772422U CN209772422U CN201920477519.7U CN201920477519U CN209772422U CN 209772422 U CN209772422 U CN 209772422U CN 201920477519 U CN201920477519 U CN 201920477519U CN 209772422 U CN209772422 U CN 209772422U
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Abstract
The utility model provides an integration regeneration factor separation enrichment preparation facilities relates to the medical instrument field. The integrated regeneration factor separation, enrichment and preparation device comprises a centrifugal tube body; one end of the centrifugal pipe body is provided with a connector which can be connected with a medical blood taking needle, and a detachable sealing cover is covered on the connector; the other end of the centrifugal pipe body is provided with a sealing piston which is pushed by a pushing piece; the periphery of the centrifugal pipe body is sleeved with an outer ring. The utility model provides an integrated device of separation enrichment preparation regeneration factor in blood, fat, marrow and cell etc. to fine cross contamination problem in the separation process has been solved.
Description
Technical Field
The utility model belongs to the technical field of the medical instrument technique and specifically relates to a preparation facilities is enriched in separation of integration regeneration factor.
Background
Platelets, one of the major components in mammalian blood, are small, biologically active cytoplasm that is cleaved from the cytoplasm of the mature bone marrow megakaryocytes. The blood component-derived rejuvenating factor is a platelet concentrate, usually extracted from whole blood by centrifugation, containing high concentrations of platelets, leukocytes and fibrin. Platelet alpha granules can secrete various growth factors after platelet activation, such as platelet-derived growth factors, vascular endothelial growth factors, transforming growth factors, insulin-like growth factors, epidermal growth factors and the like, and the growth factors have a synergistic effect and accelerate the repair of body tissues. The leucocyte and monocyte can clear local pathogen and local necrotic tissue, enhance local anti-infection capability, fibrin can construct a three-dimensional structure required by tissue repair locally, and can shrink the wound surface, promote blood coagulation, stimulate tissue regeneration and promote wound closure. A large number of basic studies and clinical trials have demonstrated that regenerative factors can significantly promote the repair and regeneration of bone and soft tissues. Wherein, the blood-derived regeneration factor can be extracted from the blood of a patient, so that the source is rich, safe and effective, and the method can be widely applied to different medical fields. Such as orthopedics, sports medicine, plastic cosmetology, stomatology, obstetrics and gynecology, neurosurgery and the like.
Regeneration factor separation enrichment preparation adopts the centrifugation usually, needs special centrifuge, is equipped with multiple supplementary consumptive material, complex operation, and easy pollution is based on this, the utility model provides an integration regeneration factor separation enrichment preparation facilities is in order to solve foretell technical problem.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an integration regeneration factor separation enrichment preparation facilities to solve the pollution problem of the secondary separation in the preparation integration regeneration factor separation process.
Based on the above purpose, the utility model provides an integrated regeneration factor separation and enrichment preparation device, which comprises a centrifugal pipe body; one end of the centrifugal pipe body is provided with a connector which can be connected with a medical blood taking needle, and a detachable sealing cover is covered on the connector;
The other end of the centrifugal pipe body is provided with a sealing piston which is pushed by a pushing piece;
The periphery of the centrifugal pipe body is sleeved with an outer ring.
Optionally, an insertion plug is arranged at the center of the sealing cover, and the insertion plug is inserted into the connector.
The connector is plugged by the plug-in plug, so that a better sealing effect can be achieved, and the centrifugal pipe body is prevented from being leaked during centrifugation.
Optionally, the plug-in plug is screwed with the connector.
The form sealing performance of spiro union is better, more can seal the connector of centrifugal tube body prevents to leak.
Optionally, the pusher is a push handle.
The push handle is convenient to use, can pull the sealing piston, and is convenient to use. In addition to the push handle, a dual/three way adapter is also possible, with additional syringe extraction, pressure push. The other approaches may also be used.
Optionally, the push handle is detachably connected to the sealing piston.
The mode of connection can be dismantled, and it is more nimble convenient to use, can pull down in the centrifugation, can install when the sealed piston of propelling movement.
Optionally, the outer end of the sealing piston is provided with a clamping hole, and the pushing handle is clamped with the clamping hole through a clamping joint at the end part.
The clamping form is convenient to disassemble and install, and the processing is simple. Other ways than snap-fitting may be used.
optionally, the sealing piston is threadedly engaged with the push handle.
The screw joint is also a common detachable connection mode, and the use is also convenient.
Optionally, the connecting ring and the centrifugal tube body are integrally formed.
The outer ring and the centrifugal tube body can be detachably connected and can also be integrally formed, so that the universal centrifugal machine can be conveniently adapted.
Optionally, the centrifugal tube body is provided with scales.
The quantity of the liquid in the liquid storage tank is judged through the scales, so that the liquid storage tank is visual, convenient, accurate and convenient to use.
optionally, the sealing piston is a rubber piston.
The rubber piston has good sealing performance, and can effectively plug the centrifugal pipe body and push and suck liquid in the pipe.
The utility model provides an integration regeneration factor separation enrichment preparation facilities, including thick mouth footpath propelling movement mouth, outer ring that centrifugal body, impeller, sealed lid, centrifugal body one end have the connector of thin mouth footpath propelling movement mouth, the other end, centrifugal body and outer ring can adaptation centrifuge adapter that uses at present generally, need not extra customization, the sealed lid of thin mouth footpath propelling movement mouth design, the impeller setting is in thick mouth footpath propelling movement mouth, the sealed piston of propelling movement front end installation, the propelling movement piece that has adorned can make sealed piston move about from top to bottom along centrifugal body inner wall.
Use utility model provides an integration regeneration factor separation enrichment preparation facilities concrete regeneration factor preparation step as follows:
S1: the connector is connected with a medical blood taking needle to carry out blood collection, the mixed blood is anti-coagulated by turning upside down, and a small-diameter pushing opening at the lower part of the centrifugal tube body is sealed by a sealing cover after the blood collection is finished.
S2: the thin-caliber push port of the centrifugal tube body is downwards placed in a centrifugal machine for first centrifugation, blood is layered after centrifugation, the sealing cover is opened, the push piece is pushed, and bottom red blood cells in the centrifugal tube body are removed through the thin-caliber push port.
S3: sealing the lower part of the centrifugal tube body through a sealing cover, shaking up the residual blood components, and centrifuging for the second time with the small-diameter pushing opening facing upwards.
S4: after the second centrifugation, the sealing cover is opened again to extract the upper plasma layer of the centrifugal tube body, and the residual regeneration factors are remained in the centrifugal tube body, namely the preparation of the separation of the integrated regeneration factors is completed.
The utility model provides an integration regeneration factor separation enrichment preparation facilities has following advantage: firstly, the medical sterile centrifugal tube body provided by the embodiment can be used as an injector for blood collection and can also be used for separating and preparing regeneration factors; twice centrifugation in the regeneration factor preparation process is finished in the same centrifugal tube body, and liquid transfer between the two times of centrifugation is not needed, so that the possibility of sample pollution in the liquid transfer process is avoided; the medical sterile centrifugal tube body provided by the embodiment can be adapted to general centrifuges on the market, additional customized centrifugal equipment is not needed, the preparation cost of the regeneration factor is greatly reduced, and the wide popularization of the regeneration factor treatment technology is effectively promoted.
Therefore, the utility model provides an integration regeneration factor separation enrichment preparation facilities can improve the convenience that regeneration factor prepared, simplifies medical staff's operation, and favourable popularization, and can furthest reduce the air pollution in the operation process, further improve the stability of regeneration factor separation preparation. In addition to separating blood components, the device can be used to separate fat, bone marrow, cell samples, and the like, and is not limited to separating blood components.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic view of an integrated regeneration factor separation and enrichment preparation apparatus provided in an embodiment of the present invention;
FIG. 2 is a schematic view of a pusher part of an integrated regeneration factor separation and enrichment preparation device provided by an embodiment of the present invention;
Fig. 3 is an enlarged view of fig. 1 at a.
Icon: 1-a centrifugal tube body; 2-a connector; 3-sealing the cover; 4-sealing the piston; 5-a pusher; 6-outer ring; 31-plug.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
in the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Integrated regeneration factor separation, enrichment and preparation device embodiment
As shown in fig. 1, in the present embodiment, a blood-derived integrated regeneration factor separation, enrichment and preparation device is provided, which includes a centrifugal tube body 1; one end of the centrifugal tube body 1 is provided with a connector 2 which can be connected with a medical blood taking needle, and a detachable sealing cover 3 is covered on the connector 2;
The other end of the centrifugal pipe body 1 is provided with a sealing piston 4, and the sealing piston 4 is pushed by a pushing piece 5;
The periphery of the centrifugal pipe body 1 is sleeved with an outer ring 6.
The utility model provides an integration regeneration factor separation enrichment preparation facilities, including centrifugal body 1, sealing piston 4, impeller 5, sealed lid 3, 1 one end of centrifugal body have connector 2, the other end of thin bore propelling movement mouth seted up thick bore propelling movement mouth, outer loop 6, centrifugal body 1 and outer loop 6 can the adaptation centrifuge adapter who uses at present generally, need not extra customization, the sealed lid 3 of thin bore propelling movement mouth design, impeller 5 sets up in thick bore propelling movement mouth, the sealing piston 4 of propelling movement front end installation, the propelling movement that is adorned can make sealing piston 4 move about from top to bottom along 1 inner wall of centrifugal body.
Use utility model provides an integration regeneration factor separation enrichment preparation facilities concrete regeneration factor preparation step as follows:
S1: the connector 2 is connected with a medical blood taking needle to perform blood collection, the mixed blood is anti-coagulated by turning upside down, and the small-diameter pushing port at the lower part of the centrifugal tube body 1 is sealed by the sealing cover 3 after the blood collection is finished.
S2: the thin-caliber push port of the centrifugal tube body 1 is downwards placed in a centrifuge for first centrifugation, blood is layered after centrifugation, the sealing cover 3 is opened, the pushing piece 5 is pushed, and bottom red blood cells in the centrifugal tube body 1 are removed through the thin-caliber push port.
s3: the lower part of the centrifugal tube body 1 is sealed by the sealing cover 3, and then the residual blood components are shaken up, and the small-diameter pushing port faces upwards for the second centrifugation.
S4: after the second centrifugation, the sealing cover 3 is opened again to extract the upper plasma layer of the centrifugal tube body 1, and the residual regeneration factors are remained in the centrifugal tube body 1, namely the preparation of the regeneration factors is completed.
The utility model provides an integration regeneration factor separation enrichment preparation facilities has following advantage: firstly, the medical sterile centrifugal tube body 1 provided by the embodiment can be used as an injector for blood collection and can also be used for separating and preparing regeneration factors; twice centrifugation in the regeneration factor preparation process is finished in the same centrifugal tube body 1, and liquid transfer between the two times of centrifugation is not needed, so that the possibility of sample pollution in the liquid transfer process is avoided; the medical sterile centrifugal tube body 1 provided by the embodiment can be adapted to general centrifuges on the market, additional customized centrifugal equipment is not needed, the preparation cost of the regeneration factor is greatly reduced, and the wide popularization of the regeneration factor treatment technology is effectively promoted.
Therefore, the utility model provides an integration regeneration factor separation enrichment preparation facilities can improve the convenience that regeneration factor prepared, simplifies medical staff's operation, and favourable popularization, and can furthest reduce the air pollution in the operation process, further improve the stability of integration regeneration factor separation enrichment preparation.
In an alternative embodiment, as shown in fig. 1, a plug 31 is provided at the center of the sealing cap 3, and the plug 31 is inserted into the connecting head 2.
The plug-in plug 31 plugs the connector 2, so that a better sealing effect can be achieved, and the centrifugal pipe body 1 is prevented from leaking during centrifugation.
Further, the plug-in plug 31 is screwed with the connector 2.
The form sealing performance of spiro union is better, more can seal the connector 2 of centrifugal tube body 1 prevents to leak.
In an alternative to this embodiment, as shown in fig. 1, the pusher 5 is a push handle.
the push handle is convenient to use, the sealing piston 4 can be pulled, and the use is convenient. In addition to the push handle, a dual/three way adapter is also possible, with additional syringe extraction, pressure push. The other approaches may also be used.
Further, the push handle is detachably connected with the sealing piston 4.
The detachable connection mode is more flexible and convenient to use, can be detached in centrifugation, and can be installed in pushing of the sealing piston 4.
Furthermore, the outer end of the sealing piston 4 is provided with a clamping hole, and the pushing handle is clamped with the clamping hole through a clamping joint at the end part.
The clamping form is convenient to disassemble and install, and the processing is simple. Other ways than snap-fitting may be used.
Further, the sealing piston 4 is screwed with the push handle.
The screw joint is also a common detachable connection mode, and the use is also convenient.
In an alternative of this embodiment, the connection ring is formed integrally with the centrifuge tube body 1.
The connecting ring and the centrifugal tube body 1 can be detachably connected and can also be integrally formed, so that the universal centrifugal machine can be conveniently adapted.
In an alternative of this embodiment, the centrifuge tube body 1 is provided with graduations.
The quantity of the liquid in the liquid storage tank is judged through the scales, so that the liquid storage tank is visual, convenient, accurate and convenient to use.
In an alternative of this embodiment, the sealing piston 4 is a rubber piston.
The rubber piston has good sealing performance, and can effectively plug the centrifugal pipe body 1 to push and suck liquid in the pipe.
finally, it should be noted that: it will be evident to those skilled in the art that the present application is not limited to the details of the foregoing illustrative embodiments, and that the present application may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the application being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (10)
1. an integrated regeneration factor separation, enrichment and preparation device is characterized by comprising a centrifugal pipe body; one end of the centrifugal pipe body is provided with a connector which can be connected with a medical blood taking needle, and a detachable sealing cover is covered on the connector;
The other end of the centrifugal pipe body is provided with a sealing piston which is pushed by a pushing piece;
The periphery of the centrifugal pipe body is sleeved with an outer ring.
2. The integrated regeneration factor separation, enrichment and preparation device as claimed in claim 1, wherein a plug is arranged in the center of the sealing cover, and the plug is inserted into the connector.
3. The integrated regeneration factor separation, enrichment and preparation device of claim 2, wherein the plug-in plug is screwed with the connector.
4. The integrated regeneration factor separation, enrichment and preparation device of claim 1, wherein the pushing member is a pushing handle.
5. the integrated regeneration factor separation, enrichment and preparation device according to claim 4, wherein the push handle is detachably connected with the sealing piston.
6. The integrated regeneration factor separation, enrichment and preparation device according to claim 5, wherein the outer end of the sealing piston is provided with a clamping hole, and the pushing handle is clamped with the clamping hole through a clamping head at the end part.
7. The integrated regeneration factor separation, enrichment and preparation device of claim 5, wherein the sealing piston is in threaded connection with the push handle.
8. The integrated recycling factor separating, enriching and preparing device according to claim 1, wherein the outer ring is integrally formed with the centrifugal tube body.
9. The integrated regeneration factor separation, enrichment and preparation device of claim 1, wherein the centrifugal tube body is provided with a scale.
10. the integrated regeneration factor separation, enrichment and preparation device of claim 1, wherein the sealing piston is a rubber piston.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920477519.7U CN209772422U (en) | 2019-04-09 | 2019-04-09 | Integrated regeneration factor separation and enrichment preparation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920477519.7U CN209772422U (en) | 2019-04-09 | 2019-04-09 | Integrated regeneration factor separation and enrichment preparation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209772422U true CN209772422U (en) | 2019-12-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920477519.7U Active CN209772422U (en) | 2019-04-09 | 2019-04-09 | Integrated regeneration factor separation and enrichment preparation device |
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| CN (1) | CN209772422U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109865603A (en) * | 2019-04-09 | 2019-06-11 | 广州医科大学附属第三医院 | Integrated regeneration factor separation and concentration preparation facilities |
| CN113976335A (en) * | 2021-10-29 | 2022-01-28 | 丁政 | Centrifugal system for preparing leukocyte-removed platelet-rich plasma and preparation method thereof |
-
2019
- 2019-04-09 CN CN201920477519.7U patent/CN209772422U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109865603A (en) * | 2019-04-09 | 2019-06-11 | 广州医科大学附属第三医院 | Integrated regeneration factor separation and concentration preparation facilities |
| CN113976335A (en) * | 2021-10-29 | 2022-01-28 | 丁政 | Centrifugal system for preparing leukocyte-removed platelet-rich plasma and preparation method thereof |
| CN113976335B (en) * | 2021-10-29 | 2024-03-29 | 湖南桔志康医疗科技有限公司 | Centrifugal system for manufacturing leukocyte-removed platelet-rich plasma and manufacturing method thereof |
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210528 Address after: 510000 room 2407, 28 Kaitai Avenue, Huangpu District, Guangzhou City, Guangdong Province (office only) Patentee after: Shikai Biotechnology (Guangzhou) Co.,Ltd. Address before: 510000 63 Duobao Road, Liwan District, Guangzhou City, Guangdong Province Patentee before: THE THIRD AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL University |
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| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220331 Address after: 528200 annex building, building 6, zone a, Hantian science and Technology City, No. 17, Shenhai Road, Guicheng Street, Nanhai District, Foshan City, Guangdong Province Patentee after: Guangdong Ruicheng Medical Technology Co.,Ltd. Address before: 510000 room 2407, 28 Kaitai Avenue, Huangpu District, Guangzhou City, Guangdong Province (office only) Patentee before: Shikai Biotechnology (Guangzhou) Co.,Ltd. |
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| TR01 | Transfer of patent right |