CN202255965U - Sampling device for dissolution test - Google Patents
Sampling device for dissolution test Download PDFInfo
- Publication number
- CN202255965U CN202255965U CN2011203917902U CN201120391790U CN202255965U CN 202255965 U CN202255965 U CN 202255965U CN 2011203917902 U CN2011203917902 U CN 2011203917902U CN 201120391790 U CN201120391790 U CN 201120391790U CN 202255965 U CN202255965 U CN 202255965U
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- China
- Prior art keywords
- stripping rotor
- sampler
- sampling
- bowl cover
- cup
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Abstract
The utility model discloses a sampling device for dissolution test, which comprises a dissolution cup (1) and a sample cup (7), wherein, the dissolution cup (1) and the sample cup (7) are connected through a sampling guide pipe (6); a sampling pump (5) is arranged on the sampling guide pipe; and in the utility model, a turning pole and a stirring head are in threaded connection, thereby facilitating the disassembly and replacement of the stirring head. The sampling device is suitable for the dissolution test by scientific research departments of large and medium-sized collages and schools, medical industry, epidemic prevention industry, environmental monitoring industry, pharmaceutical manufacturing industry, and the like.
Description
Technical field
The utility model belongs to the checkout equipment of pharmaceutical industry, particularly relates to the sampler that is used for the solubleness test.
Background technology
Dissolution rate (Dissolution rate) also claim dissolution rate, is meant under specified solvent and condition the speed and the degree of medicine stripping from solid pharmaceutical preparations such as tablet, capsule, granule.The process of measuring the solid pharmaceutical preparation dissolution rate is called dissolution rate test (Dissolution test), and it is a kind of disintegration of oral solid formulation in intestines and stomach and in vitro test method of stripping simulated.The drug dissolution inspection is a kind of effective means of estimating preparation quality and technological level; The difference that can reflect crystal formation, granularity, prescription composition, auxiliary material kind and character, the production technology etc. of main ingredient to a certain extent; It also is a kind of effective standard of estimating preparation active component bioavilability and preparation uniformity coefficient; Can effectively distinguish the difference of same kind of drug bioavailability, therefore be one of drug quality control essential items for inspection.It is generally acknowledged; Slightly solubility (referring generally to slightly soluble or insoluble in water) medicine; Because of the medicine (comprising soluble drug) that preparation prescription and production technology cause unsettled medicine of clinical efficacy and therapeutic dose and dosis toxica to be close, must set the dissolution test item in its oral solid formulation quality standard.In addition, in the prescription screening of solid pharmaceutical preparation and the technological process of production formulation process, also need the dissolution rate of exploitation formulation is done comprehensive investigation.Feasible dissolution rate test method(s) should be all must reach test findings at different time, place to the dissolution determination of same preparation or the mensuration between the different operation person to have good reappearance.
Therefore, the digestion instrument that is used for the dissolution rate test is had very high requirement, all good design should be arranged each small details.
The utility model content
The utility model technical matters to be solved provides the sampler that is used for the solubleness test, and this sampler that is used for the solubleness test can be applied to existing digestion instrument support equipment; Not only simple in structure, and easy to use.
The utility model solves the problems of the technologies described above the technical scheme that is adopted: be used for the sampler of solubleness test, comprise stripping rotor and sample cup, said stripping rotor is connected through sampling catheter with sample cup, and said sampling catheter is provided with sampling pump.
In the technique scheme, when the testing drug solvent is spent, medicine is put in the stripping rotor, in stripping rotor, adds dissolution medium; From stripping rotor, pipette sample in sample cup by sampling catheter then, wait to be detected.
The inside of said stripping rotor is provided with stirrer.
Said stirrer comprises bull stick and the stirring-head that is located at the stripping rotor axial location.
Said bull stick and stirring-head are through being threaded.
In the technique scheme, being provided with of stirrer can make the interior medicine process in leaching of stripping rotor more even.Bull stick and stirring-head can make things convenient for the dismounting and the replacing of stirring-head through the thread connecting mode setting.
The rim of a cup of said stripping rotor is provided with bowl cover, and through hole on the said bowl cover, and the through hole that said bull stick passes the bowl cover center is connected with the motor of bowl cover top; Said sampling catheter passes the through hole that departs from the bowl cover center, extend into the inside of stripping rotor.
In the technique scheme, the bowl cover setting of stripping rotor can be reduced the volatilization of the inner dissolution medium of stripping rotor.
Said sample cup connects the dissolution rate pick-up unit.
In sum, the utility model compared with prior art has following advantage:
(1), the utility model is provided with simple in structurely, manufacturing cost is lower.
(2), the utility model is applicable to the test of scientific research departments such as each big-and-middle universities and colleges, medical treatment, health and epidemic prevention, environmental monitoring, pharmaceutical industry to dissolution rate.
(4), the utility model bull stick and stirring-head be through the thread connecting mode setting, can make things convenient for the dismounting and the replacing of stirring-head.
Description of drawings
Fig. 1 is the structural representation of the utility model embodiment 1.
The corresponding name of each parts is called among the figure: 1 stripping rotor, 2 stirrers, 3 bull sticks, 4 stirring-heads, 5-sampling pump, 6-sampling catheter, 7 sample cups, 8 bowl covers, 9 through holes, 10-motor.
Embodiment
Below in conjunction with embodiment and accompanying drawing, the utility model is done further to specify, but the embodiment of the utility model is not limited thereto.
Embodiment 1:
As shown in Figure 1, be used for the sampler that solubleness is tested, comprise stripping rotor 1 and sample cup 7, said stripping rotor is connected through sampling catheter 6 with sample cup, and said sampling catheter is provided with sampling pump 5.Said sample cup connects the dissolution rate pick-up unit.
The inside of stripping rotor 1 is provided with stirrer 2.Stirrer 2 comprises the bull stick 3 and stirring-head 4 that is located at the stripping rotor axial location.Said bull stick and stirring-head are through being threaded.
The rim of a cup of said stripping rotor is provided with bowl cover 8, and through hole 9 on the said bowl cover, and the through hole that said bull stick passes the bowl cover center is connected with the motor 10 of bowl cover top; Said sampling catheter passes the through hole that departs from the bowl cover center, extend into the inside of stripping rotor.
As stated, just can realize the utility model preferably.
Claims (6)
1. be used for the sampler of solubleness test, it is characterized in that comprise stripping rotor (1) and sample cup (7), said stripping rotor is connected through sampling catheter (6) with sample cup, said sampling catheter is provided with sampling pump (5).
2. the sampler that is used for the solubleness test according to claim 1 is characterized in that the inside of said stripping rotor is provided with stirrer (2).
3. the sampler that is used for the solubleness test according to claim 2 is characterized in that said stirrer comprises bull stick (3) and the stirring-head (4) that is located at the stripping rotor axial location.
4. the sampler that is used for the solubleness test according to claim 3 is characterized in that said bull stick and stirring-head are through being threaded.
5. the sampler that is used for the solubleness test according to claim 4; It is characterized in that; The rim of a cup of said stripping rotor is provided with bowl cover (8), and through hole (9) on the said bowl cover, and the through hole that said bull stick passes the bowl cover center is connected with the motor (10) of bowl cover top; Said sampling catheter passes the through hole that departs from the bowl cover center, extend into the inside of stripping rotor.
6. according to each described sampler that is used for the solubleness test of claim 1-5, it is characterized in that said sample cup connects the dissolution rate pick-up unit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011203917902U CN202255965U (en) | 2011-10-15 | 2011-10-15 | Sampling device for dissolution test |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011203917902U CN202255965U (en) | 2011-10-15 | 2011-10-15 | Sampling device for dissolution test |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202255965U true CN202255965U (en) | 2012-05-30 |
Family
ID=46117190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011203917902U Expired - Fee Related CN202255965U (en) | 2011-10-15 | 2011-10-15 | Sampling device for dissolution test |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202255965U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109127061A (en) * | 2018-09-30 | 2019-01-04 | 合肥维奥科技有限公司 | A kind of solid medicine detection grinding dissolver |
-
2011
- 2011-10-15 CN CN2011203917902U patent/CN202255965U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109127061A (en) * | 2018-09-30 | 2019-01-04 | 合肥维奥科技有限公司 | A kind of solid medicine detection grinding dissolver |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120530 Termination date: 20121015 |