CN202255964U - Stirring and sampling device of dissolution tester - Google Patents
Stirring and sampling device of dissolution tester Download PDFInfo
- Publication number
- CN202255964U CN202255964U CN2011203917866U CN201120391786U CN202255964U CN 202255964 U CN202255964 U CN 202255964U CN 2011203917866 U CN2011203917866 U CN 2011203917866U CN 201120391786 U CN201120391786 U CN 201120391786U CN 202255964 U CN202255964 U CN 202255964U
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- CN
- China
- Prior art keywords
- stirring
- stirrer
- bull stick
- peristaltic pump
- stripping rotor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Abstract
The utility model discloses a stirring and sampling device of a dissolution tester. The stirring and sampling device comprises a dissolution cup (1), wherein a stirrer (2) is arranged inside the dissolution cup; the stirrer comprises a rotating rod (3) arranged along an axis center position of the dissolution cup, and a stirring head (4) connected with the rotating rod; the rotating rod of the stirrer is in a hollow structure; a cavity of the hollow structure is communicated with a peristaltic pump (5) outside the dissolution cup; and the other end of the peristaltic pump (5) is connected with a sample cup (7) through a pipeline. The stirrer with the cavity, provided by the utility model, realizes double functions of being used as a sampling pipe and driving the stirring head to stir; and furthermore, the utility model has a very smart design.
Description
Technical field
The utility model belongs to the checkout equipment of pharmaceutical industry, particularly relates to the stirring sampler of digestion instrument.
Background technology
Dissolution rate (Dissolution rate) also claim dissolution rate, is meant under specified solvent and condition the speed and the degree of medicine stripping from solid pharmaceutical preparations such as tablet, capsule, granule.The process of measuring the solid pharmaceutical preparation dissolution rate is called dissolution rate test (Dissolution test), and it is a kind of disintegration of oral solid formulation in intestines and stomach and in vitro test method of stripping simulated.The drug dissolution inspection is a kind of effective means of estimating preparation quality and technological level; The difference that can reflect crystal formation, granularity, prescription composition, auxiliary material kind and character, the production technology etc. of main ingredient to a certain extent; It also is a kind of effective standard of estimating preparation active component bioavilability and preparation uniformity coefficient; Can effectively distinguish the difference of same kind of drug bioavailability, therefore be one of drug quality control essential items for inspection.It is generally acknowledged; Slightly solubility (referring generally to slightly soluble or insoluble in water) medicine; Because of the medicine (comprising soluble drug) that preparation prescription and production technology cause unsettled medicine of clinical efficacy and therapeutic dose and dosis toxica to be close, must set the dissolution test item in its oral solid formulation quality standard.In addition, in the prescription screening of solid pharmaceutical preparation and the technological process of production formulation process, also need the dissolution rate of exploitation formulation is done comprehensive investigation.Feasible dissolution rate test method(s) should be all must reach test findings at different time, place to the dissolution determination of same preparation or the mensuration between the different operation person to have good reappearance.
Therefore, the digestion instrument that is used for the dissolution rate test is had very high requirement, all good design should be arranged each small details.
The utility model content
The utility model technical matters to be solved provides the stirring sampler of digestion instrument, and the stirring sampler of this digestion instrument combines stirrer, two kinds of functions of stopple coupon, and can be applied to existing digestion instrument support equipment together; Not only simple in structure, and easy to use.
The utility model solves the problems of the technologies described above the technical scheme that is adopted: the stirring sampler of digestion instrument; Comprise stripping rotor; The inside of said stripping rotor is provided with stirrer, and said stirrer comprises along the bull stick of stripping rotor shaft core position setting, the stirring-head that is connected with bull stick; The bull stick of said stirrer is a hollow-core construction, and the inner chamber of the said hollow-core construction peristaltic pump outer with being arranged on stripping rotor is communicated with; The other end of said peristaltic pump is connected to sample cup through pipeline.
In the technique scheme, behind dissolution medium of packing in the stripping rotor (being generally deionized water) and testing drug.When the dissolution rate of testing drug is tested, start stirrer, the dissolution medium in the stripping rotor is stirred according to the stirring rate of setting.When needs are taken a sample, start peristaltic pump, peristaltic pump is drawn sample through the cavity of bull stick in stripping rotor, transfer in the sample cup.
Said sample cup connects the dissolution rate pick-up unit.
The rim of a cup of said stripping rotor is provided with bowl cover, and the through hole that said bull stick passes the bowl cover center is connected with peristaltic pump.
The bull stick of said stirrer and stirring-head are through being threaded.
In sum, the utility model compared with prior art has following advantage:
(1), the utility model is provided with simple in structurely, manufacturing cost is lower.
(2), the utility model is applicable to the test of scientific research departments such as each big-and-middle universities and colleges, medical treatment, health and epidemic prevention, environmental monitoring, pharmaceutical industry to dissolution rate.
(4), the stirrer that the utlity model has cavity realized stopple coupon simultaneously and driven the double-deck function that stirring-head stirs, and designs very ingenious.
Description of drawings
Fig. 1 is the structural representation of the utility model embodiment 1.
The corresponding name of each parts is called among the figure: 1 stripping rotor, 2 stirrers, 3 bull sticks, 4 stirring-heads, 5-peristaltic pump, 7 sample cups, 8 bowl covers, 9 through holes.
Embodiment
Below in conjunction with embodiment and accompanying drawing, the utility model is done further to specify, but the embodiment of the utility model is not limited thereto.
Embodiment 1:
As shown in Figure 1, the stirring sampler of digestion instrument comprises stripping rotor 1, and the inside of said stripping rotor is provided with stirrer 2, and said stirrer comprises along the bull stick 3 of stripping rotor shaft core position setting, the stirring-head 4 that is connected with bull stick; The bull stick of said stirrer is a hollow-core construction, and the inner chamber of the said hollow-core construction peristaltic pump 5 outer with being arranged on stripping rotor is communicated with; The other end of said peristaltic pump 5 is connected to sample cup 7 through pipeline.Said sample cup connects the dissolution rate pick-up unit.The rim of a cup of said stripping rotor is provided with bowl cover 8, and the through hole 9 that said bull stick passes the bowl cover center is connected with peristaltic pump.The bull stick of said stirrer and stirring-head are through being threaded.
As stated, just can realize the utility model preferably.
Claims (4)
1. the stirring sampler of digestion instrument is characterized in that, comprises stripping rotor (1), and the inside of said stripping rotor is provided with stirrer (2), and said stirrer comprises along the bull stick (3) of stripping rotor shaft core position setting, the stirring-head (4) that is connected with bull stick; The bull stick of said stirrer is a hollow-core construction, and the inner chamber of the said hollow-core construction peristaltic pump (5) outer with being arranged on stripping rotor is communicated with; The other end of said peristaltic pump (5) is connected to sample cup (7) through pipeline.
2. the stirring sampler of digestion instrument according to claim 1 is characterized in that, said sample cup connects the dissolution rate pick-up unit.
3. the stirring sampler of digestion instrument according to claim 2 is characterized in that, the rim of a cup of said stripping rotor is provided with bowl cover (8), and the through hole (9) that said bull stick passes the bowl cover center is connected with peristaltic pump.
4. the stirring sampler of digestion instrument according to claim 3 is characterized in that, the bull stick of said stirrer and stirring-head are through being threaded.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011203917866U CN202255964U (en) | 2011-10-15 | 2011-10-15 | Stirring and sampling device of dissolution tester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011203917866U CN202255964U (en) | 2011-10-15 | 2011-10-15 | Stirring and sampling device of dissolution tester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202255964U true CN202255964U (en) | 2012-05-30 |
Family
ID=46117189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011203917866U Expired - Fee Related CN202255964U (en) | 2011-10-15 | 2011-10-15 | Stirring and sampling device of dissolution tester |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202255964U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110694520A (en) * | 2019-11-10 | 2020-01-17 | 陈丹依 | Production process and production equipment of building coating |
-
2011
- 2011-10-15 CN CN2011203917866U patent/CN202255964U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110694520A (en) * | 2019-11-10 | 2020-01-17 | 陈丹依 | Production process and production equipment of building coating |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120530 Termination date: 20121015 |