CN202582943U - Dissolution test sampling device adopting automatic control process - Google Patents
Dissolution test sampling device adopting automatic control process Download PDFInfo
- Publication number
- CN202582943U CN202582943U CN 201220211141 CN201220211141U CN202582943U CN 202582943 U CN202582943 U CN 202582943U CN 201220211141 CN201220211141 CN 201220211141 CN 201220211141 U CN201220211141 U CN 201220211141U CN 202582943 U CN202582943 U CN 202582943U
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- CN
- China
- Prior art keywords
- control process
- automatic control
- sampling
- stripping rotor
- dissolution test
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- Expired - Lifetime
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Abstract
The utility model discloses a dissolution test sampling device adopting an automatic control process. The dissolution test sampling device comprises a dissolution cup and a sample cup, wherein the dissolution cup is connected with the sample cup through a sampling guide pipe, a sampling pump is arranged on the sampling guide pipe, and a control device is arranged on the sampling pump. The dissolution test sampling device adopting the automatic control process has the advantages that a rotating rod and a stirring head are arranged in a threaded connection manner, so that the removal and replacement of the stirring head can be facilitated; and the dissolution test sampling device is applicable to the dissolution test of scientific research departments of various large and medium-sized colleges and universities, medical treatment, health and disease prevention, environmental monitoring, pharmaceutical industries and the like.
Description
Technical field
The utility model belongs to the checkout equipment of pharmaceutical industry, particularly relates to the sampler of the solubleness test of adopting automatic control process.
Background technology
Dissolution rate (Dissolution rate) also claim dissolution rate, is meant under specified solvent and condition the speed and the degree of medicine stripping from solid pharmaceutical preparations such as tablet, capsule, granule.The process of measuring the solid pharmaceutical preparation dissolution rate is called dissolution rate test (Dissolution test), and it is a kind of disintegration of oral solid formulation in intestines and stomach and in vitro test method of stripping simulated.The drug dissolution inspection is a kind of effective means of estimating preparation quality and technological level; The difference that can reflect crystal formation, granularity, prescription composition, auxiliary material kind and character, the production technology etc. of main ingredient to a certain extent; It also is a kind of effective standard of estimating preparation active component bioavilability and preparation uniformity coefficient; Can effectively distinguish the difference of same kind of drug bioavailability, therefore be one of drug quality control essential items for inspection.
It is generally acknowledged; Slightly solubility (referring generally to slightly soluble or insoluble in water) medicine; Because of the medicine (comprising soluble drug) that preparation prescription and production technology cause unsettled medicine of clinical efficacy and therapeutic dose and dosis toxica to be close, must set the dissolution test item in its oral solid formulation quality standard.In addition, in the prescription screening of solid pharmaceutical preparation and the technological process of production formulation process, also need the dissolution rate of exploitation formulation is done comprehensive investigation.Feasible dissolution rate test method(s) should be all must reach test findings at different time, place to the dissolution determination of same preparation or the mensuration between the different operation person to have good reappearance.
Therefore, the digestion instrument that is used for the dissolution rate test is had very high requirement, all good design should be arranged each small details.
The utility model content
The utility model technical matters to be solved provides the sampler of the solubleness test of adopting automatic control process, and the sampler of the solubleness test of this employing automatic control process can be applied to existing digestion instrument support equipment; Not only simple in structure, and easy to use.
The utility model solves the problems of the technologies described above the technical scheme that is adopted: the sampler that adopts the solubleness test of automatic control process; Comprise stripping rotor and sample cup; Said stripping rotor is connected through sampling catheter with sample cup; Said sampling catheter is provided with sampling pump, and said sampling pump is provided with control device.
In the technique scheme, when the testing drug solvent is spent, medicine is put in the stripping rotor, in stripping rotor, adds dissolution medium; From stripping rotor, pipette sample in sample cup by sampling catheter then, wait to be detected.
The inside of said stripping rotor is provided with stirrer.
Said stirrer comprises bull stick and the stirring-head that is located at the stripping rotor axial location, and said bull stick and stirring-head are through being threaded.
In the technique scheme, being provided with of stirrer can make the interior medicine process in leaching of stripping rotor more even.Bull stick and stirring-head can make things convenient for the dismounting and the replacing of stirring-head through the thread connecting mode setting.
The rim of a cup of said stripping rotor is provided with bowl cover, and through hole on the said bowl cover, and the through hole that said bull stick passes the bowl cover center is connected with the motor of bowl cover top.
Said sampling catheter passes the through hole that departs from the bowl cover center, extend into the inside of stripping rotor.
In the technique scheme, the bowl cover setting of stripping rotor can be reduced the volatilization of the inner dissolution medium of stripping rotor.
Said sample cup connects the dissolution rate pick-up unit.
In sum, the utility model compared with prior art has following advantage:
(1), the utility model is provided with simple in structurely, manufacturing cost is lower; Be applicable to of the test of scientific research departments such as each big-and-middle universities and colleges, medical treatment, health and epidemic prevention, environmental monitoring, pharmaceutical industry to dissolution rate.
(2), the utility model bull stick and stirring-head be through the thread connecting mode setting, can make things convenient for the dismounting and the replacing of stirring-head.
Description of drawings
Fig. 1 is the structural representation of the utility model embodiment 1.
The corresponding name of each parts is called among the figure: 1 stripping rotor, 2 stirrers, 3 bull sticks, 4 stirring-heads, 5-sampling pump, 6-sampling catheter, 7 sample cups, 8 bowl covers, 9 through holes, 10-motor, 11-control device.
Embodiment
Below in conjunction with embodiment and accompanying drawing, the utility model is done further to specify, but the embodiment of the utility model is not limited thereto.
Embodiment 1:
As shown in Figure 1; Adopt the sampler of the solubleness test of automatic control process, comprise stripping rotor 1 and sample cup 7, said stripping rotor 1 is connected through sampling catheter 6 with sample cup 7; Said sampling catheter 6 is provided with sampling pump 5, and said sampling pump 5 is provided with control device 11.Sampling pump 5 starts as required the time, can control sampling pump 5 rapidly and accurately through control device 11, and the material in the stripping rotor 1 is extracted through sampling catheter 6, accurately makes things convenient for, and has improved work efficiency simultaneously.
The inside of said stripping rotor 1 is provided with stirrer 2.
Said stirrer 2 comprises the bull stick 3 and stirring-head 4 that is located at stripping rotor 1 axial location, and said bull stick 3 and stirring-head 4 are through being threaded.Being provided with of stirrer 2 can make stripping rotor 1 interior medicine process in leaching more even.Bull stick 3 passes through the thread connecting mode setting with stirring-head 4, can make things convenient for the dismounting and the replacing of stirring-head 4.
The rim of a cup of said stripping rotor 1 is provided with bowl cover 8, and through hole 9 on the said bowl cover 8, and the through hole 9 that said bull stick 3 passes bowl cover 8 centers is connected with the motor 10 of bowl cover 9 tops.
Said sampling catheter 6 passes the through hole 9 that departs from bowl cover 8 centers, extend into the inside of stripping rotor 1.The bowl cover 8 of stripping rotor 1 is provided with the volatilization of the dissolution medium that can reduce stripping rotor 1 inside.
Said sample cup 7 connects the dissolution rate pick-up unit.Through the dissolution rate pick-up unit sample that takes out is detected.
As stated, just can realize the utility model preferably.
Claims (5)
1. adopt the sampler of the solubleness test of automatic control process; Comprise stripping rotor (1) and sample cup (7); Said stripping rotor (1) is connected through sampling catheter (6) with sample cup (7); Said sampling catheter (6) is provided with sampling pump (5), it is characterized in that: said sampling pump (5) is provided with control device (11).
2. the sampler of the solubleness test of employing automatic control process according to claim 1, it is characterized in that: the inside of said stripping rotor (1) is provided with stirrer (2).
3. the sampler of the solubleness test of employing automatic control process according to claim 2; It is characterized in that: said stirrer (2) comprises bull stick (3) and the stirring-head (4) that is located at stripping rotor (1) axial location, and said bull stick (3) and stirring-head (4) are through being threaded.
4. the sampler of the solubleness test of employing automatic control process according to claim 3; It is characterized in that: the rim of a cup of said stripping rotor (1) is provided with bowl cover (8); And said bowl cover (8) is gone up through hole (9); The through hole (9) that said bull stick (3) passes bowl cover (8) center is connected with the motor (10) of bowl cover (8) top, and said sampling catheter (6) passes the through hole (9) that departs from bowl cover (8) center, extend into the inside of stripping rotor (1).
5. the sampler of testing according to the solubleness of each described employing automatic control process of claim 1-4 is characterized in that: said sample cup (7) connects the dissolution rate pick-up unit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220211141 CN202582943U (en) | 2012-05-11 | 2012-05-11 | Dissolution test sampling device adopting automatic control process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220211141 CN202582943U (en) | 2012-05-11 | 2012-05-11 | Dissolution test sampling device adopting automatic control process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202582943U true CN202582943U (en) | 2012-12-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220211141 Expired - Lifetime CN202582943U (en) | 2012-05-11 | 2012-05-11 | Dissolution test sampling device adopting automatic control process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202582943U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103048165A (en) * | 2011-10-15 | 2013-04-17 | 四川汇利实业有限公司 | Sampling device for testing dissolubility by adopting automatic control process |
| CN112284822A (en) * | 2020-09-30 | 2021-01-29 | 深圳市锐拓仪器设备有限公司 | Automatic sampling device of dissolution instrument by flow cell method |
-
2012
- 2012-05-11 CN CN 201220211141 patent/CN202582943U/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103048165A (en) * | 2011-10-15 | 2013-04-17 | 四川汇利实业有限公司 | Sampling device for testing dissolubility by adopting automatic control process |
| CN112284822A (en) * | 2020-09-30 | 2021-01-29 | 深圳市锐拓仪器设备有限公司 | Automatic sampling device of dissolution instrument by flow cell method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Good Doctor Pharmaceutical Group Co., Ltd. Assignor: Sichuan Huili Industrial Co., Ltd. Contract record no.: 2012510000196 Denomination of utility model: Sampling device for testing dissolubility by adopting automatic control process Granted publication date: 20121205 License type: Exclusive License Record date: 20121226 |
|
| LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20121205 |