CN206470256U - A kind of digestion instrument - Google Patents
A kind of digestion instrument Download PDFInfo
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- CN206470256U CN206470256U CN201621278230.5U CN201621278230U CN206470256U CN 206470256 U CN206470256 U CN 206470256U CN 201621278230 U CN201621278230 U CN 201621278230U CN 206470256 U CN206470256 U CN 206470256U
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- cup
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- digestion instrument
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Abstract
The utility model discloses a kind of digestion instrument, rabbling mechanism including liftable control cabinet and on control cabinet, water tank is provided with below rabbling mechanism, some circular holes are provided with water tank, the dissolving cup that cup edge is mounted with circular hole is placed with circular hole, the circular is symmetrically arranged with the fitting that can rotate to the cup edge for compressing dissolving cup.The utility model causes in whipping process that the dissolving cup will not shake by the setting of fitting, so as to ensure that the sample in the dissolving cup on water tank is all stirred by same degree, so as to ensure the precision of final experimental results.
Description
Technical field
The utility model is related to medicine secondary development process equipment field, particularly a kind of digestion instrument.
Background technology
Dissolution rate（Dissolution rate）Also referred to as dissolution rate, refer to defined solvent and under the conditions of, medicine from
The speed and degree of dissolution in the solid pharmaceutical preparations such as tablet, capsule, granule.The process for determining solid pharmaceutical preparation dissolution rate is referred to as molten
Out-degree is tested（Dissolution test）, it is a kind of body for simulating oral solid formulation disintegration in the gastrointestinal tract and dissolution
Outer test method.Drug dissolution inspection is a kind of effective means for evaluating preparation quality and technological level, can be in certain journey
Reflect the difference of crystal formation, granularity, composition, auxiliary material kind and property, the production technology of main ingredient etc. on degree, be also to evaluate preparation
A kind of effective standard of active ingredients Biogenic availability and the preparation uniformity, can effectively distinguish same drug bioavailability
Difference, therefore be one of Drug's control essential items for inspection.
And when dissolution rate is detected, commonly used instrument is exactly digestion instrument, existing digestion instrument structure includes 8-12
Individual dissolving cup, agitating paddle is stretched in dissolving cup, and agitating paddle is being dissolved by connected agitating shaft under the driving of driving head
Stirred in cup, because the positioning of driving head is inaccurate, cause agitating shaft center and dissolving cup center once running
Afterwards it is difficult to ensure with one heart, to cause agitating paddle different to the stirring extent of each dissolving cup again, the measuring accuracy of experiment is influenceed.
In view of the above-mentioned problems, Publication No. CN202676690U Chinese patent discloses a solution；
The program is specially a kind of general-purpose digestion instrument, and its topmost is driving head supporting plate, and foot is on base, base
Water tank is fixedly installed, there are 8~12 molten cups to be arranged and be suspended in water tank by front and rear two row, the axis perpendicular of molten cup is in driving head
Be equipped with an agitating paddle in supporting plate, each molten cup, each agitating paddle is fixedly connected with the lower end of agitating shaft, agitating shaft it is upper
Hold overcoat axle sleeve and the hole through in driving head supporting plate is connected with driving head；The dead astern of water tank is provided with heater box, heating
The bottom of case is fixedly connected with heater box bottom plate；The dead astern of agitating shaft sets gas spring and three straight tubes, gas spring and three straight tubes
Upper end is all connected with that driving head supporting plate, lower part are inserted in heater box, lower end is connected with heater box bottom plate；Three straight tubes are in
Isosceles triangle is distributed, and gas spring is obliquely installed and positioned at the centre of three straight tubes from the front to the back；Driving head include motor, belt and
Gear, the upper end of each agitating shaft is set with a gear, and all gears are connected by belt with motor, and motor connects
Connect PLC；Provided with the linear bearing arranged above and below two axial directions in straight tube inner chamber；It is inserted in two straight lines in the lower end of drive shaft
In bearing, the affixed driving head supporting plate in upper end；The bottom of driving head supporting plate is provided with spring locking bar mechanism, when driving head drops to
During bottom position, spring locking bar mechanism lockable driving head.
The general-purpose digestion instrument is driven by gas spring realizes that driving head is vertically moved up or down, it is ensured that agitating shaft and dissolving cup are concentric, one
Determine to improve the precision and efficiency of test in degree, but the dissolving cup in the general-purpose digestion instrument be directly placed on dissolving frame with
Hot water contacts' inside water tank, so when agitating paddle easily drives dissolving cup to rock when solution is stirred in dissolving cup,
It equally can also influence the precision of test result.
Utility model content
In view of the deficienciess of the prior art, the purpose of this utility model is to provide a kind of digestion instrument, the digestion instrument is being stirred
When mixing solution in dissolving cup, dissolving cup will not shake, it is ensured that the precision of experimental results.
Above-mentioned technical purpose of the present utility model technical scheme is that：
Below a kind of digestion instrument, including liftable control cabinet and the rabbling mechanism on control cabinet, rabbling mechanism
It is provided with water tank, water tank and is provided with some circular holes, the dissolving cup that cup edge is mounted with circular hole, the circular hole week is placed with circular hole
Enclose the fitting for being symmetrically arranged with and can rotate to the cup edge for compressing dissolving cup.
Using said structure, first added water in water tank, then water is heated, then by the hot water in water tank in dissolving cup
Sample carries out heating water bath, when being stirred to the sample that is placed in dissolving cup, can first by the fitting of circular rotate to
When abutting, then the sample in dissolving cup being stirred with dissolving cup cup edge by rabbling mechanism, dissolving cup would not shake
It is dynamic, so as to ensure that the sample in the dissolving cup on water tank is all stirred by same degree, so as to ensure final experiment test knot
The precision of fruit, only needs to outward winding fitting from cup edge, disengaging it from cup edge just can take out molten when needing and taking out dissolving cup
Solve cup.
Be further arranged to the fitting and be set to semicircle, be connected by screw between the fitting center of circle and water tank and
Fitting can rotate around screw, be socketed with spring on the screw, spring in its natural state when two ends respectively with screw head
And fitting upper surface is abutted.
Using said structure, when fitting is threaded to being abutted above dissolving cup cup edge, fitting and screw head
Distance Shortened so that the compression deformation of the spring between screw head and fitting, so that the downward pressure of pressure downward to fitting
Power, makes fitting pressed glass edge, it is ensured that even in the case where stirring is more violent, dissolving cup will not also shake, when
When needing to take out dissolving cup, dissolving cup cup edge is disengaged it from as long as first rotating fitting around screw, spring, which recovers former length, just can
Take out dissolving cup.
Being further arranged to the rabbling mechanism includes stirring motor and the puddler with stirring motor arbor grafting, stirring
Boom end is provided with agitating paddle.
Using said structure, puddler and stirring motor arbor socket connection, convenient installation and dismounting to puddler,
Consequently facilitating being cleaned to puddler and agitating paddle.
It is further arranged to the dissolving cup top and is provided with cup lid, the cup lid includes diameter identical lower cover and with
The connection of lid center and can around lower cover central rotation upper lid, be provided with that width is identical between lower cover and upper lid and width be more than and stirred
The strip slot of shank diameter.
Using said structure, when needing to be stirred the sample in dissolving cup, scatter and disappear, can first rotate to reduce heat
Upper lid, makes lid be overlapped with the strip slot of lower cover in the vertical direction, then cup lid is covered on dissolving cup, makes puddler
In strip slot between upper lid and lower cover, then the sample in dissolving cup is stirred just be effectively reduced in dissolving cup it is hot
That measures scatters and disappears, while when sample only needs to independent water-bath, it is only necessary to the upper lid of cup lid is rotated around lower cover, makes lid and lower cover
Between strip slot stagger, then cup lid is covered on dissolving cup, can so reduce the loss of sample heat in dissolving cup.
The diameter for being further arranged to the fitting is more than distance of the screw away from cup edge and less than screw away from cup lid edge
Distance.
Using said structure, it is ensured that dissolving cup is when covering cup lid, and fitting, which can be rotated to dissolving cup cup edge, to abut,
Covering and opening for cup lid is not interfered with simultaneously.
It is further arranged to the cover rim and is provided with driving lever.
Using said structure, the setting of driving lever directly by stirring driving lever upper lid can just rotated around lower cover, so that
It is convenient that upper lid is stirred.
It is further arranged to be placed with the dissolving cup and can accommodates the box body of tablet, box surface is provided with aperture.
Using said structure, when simulating special medicine as reacted more violent medicine dissolution situation in human gastric juice,
Medicine can be prevented in the box body, the solution in dissolving cup enters box body by aperture and reacted with drug contact so that reaction
It is confined in box body simulate more real environment, it is ensured that the degree of accuracy of experimental result.
It is further arranged to the hood-like body that the box body is set to metal net surface structure.
Using said structure, the solution in dissolving cup can be entered by wire netting in the hood-like body with the medicine in hood-like body
Product are reacted.
Being further arranged to the water tank bottom place mat has one layer of rubber slab.
Using said structure, rubber slab can effectively play the effect of buffering so that water tank bottom have preferably it is shockproof and
Resistant to damage is acted on, while being further ensured that the stability of dissolving cup in whipping process, it is ensured that the accuracy of experimental data.
In summary, the utility model has the advantages that：
1. being caused by the setting of fitting in whipping process, the dissolving cup will not shake, so as to ensure water tank
On dissolving cup in sample all stirred by same degree, so as to ensure the precision of final experimental results；
2. the setting of upper lid and lower cover to be adjusted as needed in experimentation in cup lid, reduce in dissolving cup
Sample heat scatter and disappear；
3. the hood-like body of metal net surface structure can be placed individually into dissolving cup, dissolution rate survey can be carried out for special medicine
Examination.
Brief description of the drawings
Fig. 1 is the structure chart of the present embodiment；
Fig. 2 is the profile of the present embodiment；
Fig. 3 is A portions enlarged drawing in the present embodiment Fig. 1；
Fig. 4 is the structure chart of the present embodiment cup lid.
Reference：1. control cabinet；2. water tank；3. circular hole；4. dissolving cup；41. cup edge；5. fitting；6. screw；7. bullet
Spring；8. puddler；9. agitating paddle；10. cup lid；101. lower cover；102. on cover；1021. driving lever；11. strip slot；12. hood-like body；
13. rubber slab.
Embodiment
The utility model is described in further detail below in conjunction with accompanying drawing.
A kind of digestion instrument, as Figure 1-Figure 2：Rabbling mechanism including control cabinet 1 and on control cabinet 1, stirring
Mechanism includes stirring motor and the puddler 8 with stirring motor arbor grafting, and the end of puddler 8 is provided with agitating paddle 9, control cabinet
1 liftable causes the rabbling mechanism lifting of control cabinet 1 one, rabbling mechanism lower section can be provided with the water tank that PPSU materials are made
2, the bottom place mat of water tank 2, which has to be provided with one layer of rubber slab 13, water tank 2 in some circular holes 3, circular hole 3, is placed with cup edge 41 and circle
The dissolving cup 4 that hole 3 is mounted, puddler 8 can decline with control cabinet 1 makes the agitating paddle 9 of the end of puddler 8 drop into dissolving cup 4,
Dissolving cup 4 is covered with cup lid 10.
As shown in Figures 1 and 3, the circular fitting 5 of two halves, the center of circle of fitting 5 and water tank are symmetrically arranged with around circular hole 3
Connected between 2 by screw 6 and fitting 5 can rotate around screw 6, spring 7 is socketed with screw 6, spring 7 is in its natural state
When two ends abutted respectively with the head of screw 6 and the upper surface of fitting 5, the diameter of fitting 5 is more than distance of the screw 6 away from cup edge 41
And less than distance of the screw 6 away from the edge of cup lid 10, rotatable fitting 5 makes fitting 5 be pressed the cup edge 41 of dissolving cup 4
Tightly.
As shown in Figures 2 and 4, cup lid 10 includes diameter identical lower cover 101 and is connected with the center of lower cover 101 and can be under
The upper lid 102 of the central rotation of lid 101, be provided with that width is identical between lower cover 101 and upper lid 102 and width to be more than puddler 8 straight
The strip slot 11 in footpath, the upper edge of lid 102, which is provided with driving lever 1021, dissolving cup 4 to be placed with, can accommodate the hood-like body 12 of tablet, cover
Shape body 12 is set to stainless steel net surface structure.
Operation principle：First added water in water tank 2, then water is heated, then by the hot water in water tank 2 in dissolving cup 4
Sample carries out heating water bath, when the sample to being placed in dissolving cup 4 is stirred, first can revolve two fittings 5 around circular hole 3
Abutted to the top of cup edge 41, fitting 5 and the Distance Shortened on the head of screw 6 so that between the head of screw 6 and fitting 5
The compression of spring 7, so that the downward pressure that pressed downwards to fitting 5, makes the pressed glass of fitting 5 along 41, it is ensured that even
In the case where agitating paddle 9 is more violent, dissolving cup 4 will not also shake, when needing to take out dissolving cup 4, as long as first will
Fitting 5 disengages it from cup edge 41 around the rotation of screw 6, and spring 7, which recovers former length, just can take out dissolving cup 4.
Cup lid 10 is set to the form that lid 102 rotates around lower cover 101 simultaneously, and is set between lower cover 101 and upper lid 102
There is width identical and width is more than the strip slot 11 of the diameter of puddler 8, the driving lever 1021 at the edge of lid 102 can be stirred as needed
Exposing and hiding for strip slot 11 is realized, so that the loss of sample heat in dissolving cup 4 is controlled, so as to reach regulation and control experimentation
Purpose.
In addition it can be put into equipped with examining the hood-like body 12 of medicine to be tested, enhanced according to experiment demand in dissolving cup 4
The applicability of the digestion instrument.
This specific embodiment is only to explain of the present utility model, and it is not to limitation of the present utility model, ability
Field technique personnel can make the modification without creative contribution to the present embodiment as needed after this specification is read, but
As long as all being protected in right of the present utility model by Patent Law.
Claims (9)
1. a kind of digestion instrument, including liftable control cabinet（1）And installed in control cabinet（1）On rabbling mechanism, rabbling mechanism
Lower section is provided with water tank（2）, water tank（2）On be provided with some circular holes（3）, circular hole（3）In be placed with cup edge（41）With circular hole（3）
The dissolving cup of mounting（4）, it is characterized in that：The circular hole（3）Surrounding, which is symmetrically arranged with, can rotate to compression dissolving cup（4）Cup edge
（41）Fitting（5）.
2. a kind of digestion instrument according to claim 1, it is characterized in that：The fitting（5）It is set to semicircle, fitting
（5）The center of circle and water tank（2）Between pass through screw（6）Connection and fitting（5）Can be around screw（6）Rotation, the screw（6）Upper set
It is connected to spring（7）, spring（7）When in its natural state two ends respectively with screw（6）Head and fitting（5）Upper surface is abutted.
3. a kind of digestion instrument according to claim 2, it is characterized in that：The rabbling mechanism include stirring motor and with stirring
The puddler of motor crankshaft grafting（8）, puddler（8）End is provided with agitating paddle（9）.
4. a kind of digestion instrument according to claim 3, it is characterized in that：The dissolving cup（4）Top is provided with cup lid（10）,
The cup lid（10）Including diameter identical lower cover（101）And and lower cover（101）Center connects and can be around lower cover（101）Revolve at center
The upper lid turned（102）, lower cover（101）With upper lid（102）Between be provided with that width is identical and width is more than puddler（8）Diameter
Strip slot（11）.
5. a kind of digestion instrument according to claim 4, it is characterized in that：The fitting（5）Diameter be more than screw（6）Away from
Cup edge（41）Distance and less than screw（6）Away from cup lid（10）The distance at edge.
6. a kind of digestion instrument according to claim 4, it is characterized in that：The upper lid（102）Edge is provided with driving lever
（1021）.
7. a kind of digestion instrument according to claim 1, it is characterized in that：The dissolving cup（4）In be placed with and can accommodate tablet
Box body, box surface is provided with aperture.
8. a kind of digestion instrument according to claim 7, it is characterized in that：The box body is set to the hood-like of metal net surface structure
Body（12）.
9. a kind of digestion instrument according to claim 1, it is characterized in that：The water tank（2）Bottom place mat has one layer of rubber slab
（13）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621278230.5U CN206470256U (en) | 2016-11-24 | 2016-11-24 | A kind of digestion instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621278230.5U CN206470256U (en) | 2016-11-24 | 2016-11-24 | A kind of digestion instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206470256U true CN206470256U (en) | 2017-09-05 |
Family
ID=59709180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621278230.5U Active CN206470256U (en) | 2016-11-24 | 2016-11-24 | A kind of digestion instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206470256U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108444781A (en) * | 2018-02-28 | 2018-08-24 | 微思行（北京）科技有限公司 | Full-automatic levigation instrument |
| CN114252526A (en) * | 2021-12-20 | 2022-03-29 | 辰欣药业股份有限公司 | Valsartan and hydrochlorothiazide tablet dissolution device and dissolution curve detection method |
-
2016
- 2016-11-24 CN CN201621278230.5U patent/CN206470256U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108444781A (en) * | 2018-02-28 | 2018-08-24 | 微思行（北京）科技有限公司 | Full-automatic levigation instrument |
| CN114252526A (en) * | 2021-12-20 | 2022-03-29 | 辰欣药业股份有限公司 | Valsartan and hydrochlorothiazide tablet dissolution device and dissolution curve detection method |
| CN114252526B (en) * | 2021-12-20 | 2022-10-11 | 辰欣药业股份有限公司 | Valsartan and hydrochlorothiazide tablet dissolution device and dissolution curve detection method |
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 311199 Nanyuan street, Yuhang District, Zhejiang, Jiangsu Province, Su Village (security bridge) Patentee after: Hangzhou Yipin Jiuzhitang Pharmaceutical Co. Ltd. Address before: 311199 Nanyuan street, Yuhang District, Zhejiang, Jiangsu Province, Su Village (security bridge) Patentee before: Hangzhou Huadong medicine group Jiuzhitang Pharmaceutical Co. Ltd. |