CN1964740A - 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物 - Google Patents

治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物 Download PDF

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Publication number
CN1964740A
CN1964740A CNA2005800180446A CN200580018044A CN1964740A CN 1964740 A CN1964740 A CN 1964740A CN A2005800180446 A CNA2005800180446 A CN A2005800180446A CN 200580018044 A CN200580018044 A CN 200580018044A CN 1964740 A CN1964740 A CN 1964740A
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CN
China
Prior art keywords
antibody
alkyl
αvβ5
aryl
alula
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Pending
Application number
CNA2005800180446A
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English (en)
Chinese (zh)
Inventor
迪安·谢泼德
阿马·阿塔基利特
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University of California San Diego UCSD
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University of California San Diego UCSD
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Publication of CN1964740A publication Critical patent/CN1964740A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CNA2005800180446A 2004-04-02 2005-03-30 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物 Pending CN1964740A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55917504P 2004-04-02 2004-04-02
US60/559,175 2004-04-02

Publications (1)

Publication Number Publication Date
CN1964740A true CN1964740A (zh) 2007-05-16

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ID=35064346

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CNA2005800180446A Pending CN1964740A (zh) 2004-04-02 2005-03-30 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物

Country Status (14)

Country Link
US (2) US20050226865A1 (enExample)
EP (2) EP2394662B1 (enExample)
JP (2) JP5223072B2 (enExample)
CN (1) CN1964740A (enExample)
AU (1) AU2005229015C1 (enExample)
CA (1) CA2562038C (enExample)
CY (1) CY1114497T1 (enExample)
DK (1) DK1734996T3 (enExample)
ES (2) ES2671522T3 (enExample)
HR (1) HRP20130782T1 (enExample)
PL (1) PL1734996T3 (enExample)
PT (1) PT1734996E (enExample)
RS (1) RS52918B (enExample)
WO (1) WO2005094391A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102481347A (zh) * 2009-07-24 2012-05-30 加州大学董事会 治疗和预防整合素αvβ5相关疾病的方法及组合物
CN105392801A (zh) * 2013-03-15 2016-03-09 比奥根Ma公司 使用抗αvβ5抗体治疗和预防急性肾损伤
CN107001469A (zh) * 2014-09-12 2017-08-01 比奥根Ma公司 人源化抗‑αvβ5抗体及其用途

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US11339221B2 (en) 2017-11-01 2022-05-24 Tufts Medical Center, Inc. Bispecific antibody constructs and methods of use

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102481347A (zh) * 2009-07-24 2012-05-30 加州大学董事会 治疗和预防整合素αvβ5相关疾病的方法及组合物
CN105392801A (zh) * 2013-03-15 2016-03-09 比奥根Ma公司 使用抗αvβ5抗体治疗和预防急性肾损伤
CN107001469A (zh) * 2014-09-12 2017-08-01 比奥根Ma公司 人源化抗‑αvβ5抗体及其用途

Also Published As

Publication number Publication date
ES2411965T3 (es) 2013-07-09
JP5681149B2 (ja) 2015-03-04
JP2007531733A (ja) 2007-11-08
EP2394662B1 (en) 2018-03-21
WO2005094391A2 (en) 2005-10-13
ES2671522T3 (es) 2018-06-06
US20050226865A1 (en) 2005-10-13
AU2005229015A1 (en) 2005-10-13
AU2005229015B2 (en) 2012-08-30
CA2562038C (en) 2017-04-25
HK1098077A1 (en) 2007-07-13
WO2005094391A3 (en) 2005-12-01
PT1734996E (pt) 2013-07-18
EP2394662A2 (en) 2011-12-14
EP1734996A4 (en) 2008-09-10
HRP20130782T1 (en) 2013-09-30
EP2394662A3 (en) 2012-02-22
RS52918B (sr) 2014-02-28
CA2562038A1 (en) 2005-10-13
DK1734996T3 (da) 2013-06-10
EP1734996B1 (en) 2013-05-22
CY1114497T1 (el) 2016-10-05
EP1734996A2 (en) 2006-12-27
JP2013028611A (ja) 2013-02-07
US7815908B2 (en) 2010-10-19
PL1734996T3 (pl) 2013-09-30
US20090280118A1 (en) 2009-11-12
AU2005229015C1 (en) 2013-01-17
JP5223072B2 (ja) 2013-06-26

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