CN1954855B - 含玻璃酸钠的治疗眼底黄斑变性的眼用制剂及其制备方法 - Google Patents
含玻璃酸钠的治疗眼底黄斑变性的眼用制剂及其制备方法 Download PDFInfo
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- CN1954855B CN1954855B CN2005100307237A CN200510030723A CN1954855B CN 1954855 B CN1954855 B CN 1954855B CN 2005100307237 A CN2005100307237 A CN 2005100307237A CN 200510030723 A CN200510030723 A CN 200510030723A CN 1954855 B CN1954855 B CN 1954855B
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- ethyl acetate
- folium digitalis
- esculetin
- glucoside
- dried
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Abstract
Description
载体 | 玻璃酸钠耐受浓度(w/v%) | 刺激程度积分 |
玻璃酸钠 | 1 | 5 |
卡波姆 | 0.4 | 6 |
HPMC | 0.8 | 6 |
刺激程度 | 积分 |
无刺激性 | 0~3 |
轻度刺激性 | 4~8 |
中度刺激性 | 9~12 |
强度刺激性 | 13~16 |
时间(天) | 0 | 5 | 10 |
外观性状 | 无色澄明溶液 | 无色澄明溶液 | 无色澄明溶液 |
pH值 | 5.51 | 5.54 | 5.53 |
澄清度 | 澄清 | 澄清 | 澄清 |
洋地黄叶和七叶亭苷含量/初值(%)1 | 100.63 | 100.67 | 100.28 |
洋地黄叶和七叶亭苷有关物质(%) | 0.51 | 0.50 | 0.51 |
渗透压(mOsM) | 298 | 295 | 297 |
组分 | 对比例1 |
洋地黄叶干提物 | 0.049g |
七叶亭苷 | 0.1g |
硼酸 | 0 |
硼砂 | 0 |
苯扎氯铵 | 0.01g |
适量盐酸或氢氧化钠 | 调节pH为6.0 |
注射用水 | 加至100ml |
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2005100307237A CN1954855B (zh) | 2005-10-26 | 2005-10-26 | 含玻璃酸钠的治疗眼底黄斑变性的眼用制剂及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN2005100307237A CN1954855B (zh) | 2005-10-26 | 2005-10-26 | 含玻璃酸钠的治疗眼底黄斑变性的眼用制剂及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1954855A CN1954855A (zh) | 2007-05-02 |
CN1954855B true CN1954855B (zh) | 2012-01-04 |
Family
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Application Number | Title | Priority Date | Filing Date |
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CN2005100307237A Active CN1954855B (zh) | 2005-10-26 | 2005-10-26 | 含玻璃酸钠的治疗眼底黄斑变性的眼用制剂及其制备方法 |
Country Status (1)
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CN (1) | CN1954855B (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109925307A (zh) * | 2018-12-29 | 2019-06-25 | 广东宏盈科技有限公司 | 一种异黄酮与玻璃酸钠药物组合物及其应用 |
CN115804752B (zh) * | 2023-02-07 | 2023-08-11 | 天津康哲维盛医药科技发展有限公司 | 一种含有洋地黄苷的滴眼液的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0163924A1 (de) * | 1984-05-02 | 1985-12-11 | Roshdy Dr. Ismail | Vitaminhaltiges Mittel zur Behandlung und zum Schutz der Schleimhäute sowie Verwendung von Vitamin E zur Herstellung des Mittels |
CN1183302A (zh) * | 1996-11-22 | 1998-06-03 | 凌沛学 | 含有玻璃酸钠的滴眼液及其制作方法 |
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2005
- 2005-10-26 CN CN2005100307237A patent/CN1954855B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0163924A1 (de) * | 1984-05-02 | 1985-12-11 | Roshdy Dr. Ismail | Vitaminhaltiges Mittel zur Behandlung und zum Schutz der Schleimhäute sowie Verwendung von Vitamin E zur Herstellung des Mittels |
CN1183302A (zh) * | 1996-11-22 | 1998-06-03 | 凌沛学 | 含有玻璃酸钠的滴眼液及其制作方法 |
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CN1954855A (zh) | 2007-05-02 |
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GR01 | Patent grant | ||
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Owner name: SHANGHAI SINE PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME: SINE PHARMACEUTICAL FACTORY CO., LTD. |
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Address after: 201206 Pudong New Area new Jinqiao Road, Shanghai, No. 905 Patentee after: Shanghai Sine Pharmaceutical Co., Ltd. Address before: 201206 No. 787-791, Tang Lu, Shanghai, Pudong Patentee before: Sine Pharmaceutical Factory Co., Ltd. |
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EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20070502 Assignee: SHANGHAI XINYI JINZHU PHARMACEUTICAL CO., LTD. Assignor: Shanghai Sine Pharmaceutical Co., Ltd. Contract record no.: 2012990000948 Denomination of invention: Eye preparation containing sodium hyaluronate for treating fundus macular degeneration and its preparation method Granted publication date: 20120104 License type: Exclusive License Record date: 20121227 |
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Address after: 201206 Pudong New Area new Jinqiao Road, Shanghai, No. 905 Patentee after: Shanghai Xinyi Pharmaceutical Co. Ltd.. Address before: 201206 Pudong New Area new Jinqiao Road, Shanghai, No. 905 Patentee before: Shanghai Sine Pharmaceutical Co., Ltd. |