CN1939414A - 一种具有抗菌消炎作用的药物组合物 - Google Patents
一种具有抗菌消炎作用的药物组合物 Download PDFInfo
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- CN1939414A CN1939414A CN 200510044767 CN200510044767A CN1939414A CN 1939414 A CN1939414 A CN 1939414A CN 200510044767 CN200510044767 CN 200510044767 CN 200510044767 A CN200510044767 A CN 200510044767A CN 1939414 A CN1939414 A CN 1939414A
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- Prior art keywords
- houttuyninum
- neo
- radix tinosporae
- pharmaceutically acceptable
- injection
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Abstract
Description
组别 | 剂量(mg/kg) | 动物数(只) | 炎症肿胀度(mg) | 降低率(%) |
空白对照组新鱼腥草素钠组组合物(8mg+10mg)组组合物(8mg+20mg)组组合物(8mg+30mg)组组合物(8mg+40mg)组组合物(8mg+50mg)组组合物(8mg+60mg)组组合物(8mg+70mg)组组合物(8mg+80mg)组组合物(8mg+90mg)组阳性对照组 | 888888888888 | 101010101010101010101010 | 11.2±0.959.6±0.81*8.5±0.76*7.0±0.58**6.7±0.46**7.1±0.51**7.9±0.60*8.1±0.72*8.5±0.75*8.6±0.78*8.8±0.86*6.0±0.87** | -14.2924.1137.5040.1836.6129.4627.6824.1123.2121.4346.43 |
组别 | 剂量(mg/kg) | 动物数(只) | 炎症肿胀度(mg) | 降低率(%) |
空白对照组新鱼腥草素钠组组合物(8mg+20mg)组组合物(8mg+30mg)组组合物(8mg+40mg)组阳性对照组 | 444444 | 101010101010 | 152.34±75.42124.12±54.23*94.56±37.24**90.56±28.97**95.27±34.19**87.43±48.67** | -18.5237.9340.5537.4642.61 |
组别 | 剂量(mg/kg) | 动物数(只) | 腹腔洗出液吸收度(OD) |
空白对照组新鱼腥草素钠组组合物高剂量组组合物中剂量组组合物低剂量组阳性对照组 | 88241688 | 101010101010 | 0.586±0.1560.487±0.098*0.429±0.086**0.453±0.078**0.477±0.091**0.387±0.041** |
细菌 | 本发明药物组合物(mg/ml) | 头孢哌酮钠舒巴坦钠(μg/ml) |
金黄色葡萄球菌表皮葡萄球菌卡他球菌类白喉杆菌大肠杆菌福氏痢疾杆菌菌鸭沙门氏菌小肠结肠炎耶氏菌肺炎克雷伯菌绿脓杆菌 | 1.21.21.21.21.21.21.21.21.22.4 | 1.601.600.800.800.800.400.800.400.4016.80 |
菌种 | 组别 | 药品 | 24h生存数 | 24h死亡数 |
金黄色葡萄球菌大肠杆菌肺炎双球菌 | 123412341234 | 组合物新鱼腥草素钠盐酸左氧氟沙星注射液氯化钠注射液组合物新鱼腥草素钠盐酸左氧氟沙星注射液氯化钠注射液组合物注新鱼腥草素钠盐酸左氧氟沙星注射液氯化钠注射液 | 979198919790 | 13191*21913110 |
试管号 | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
组合物注射液(ml)生理盐水(ml)蒸馏水(ml)2%红细胞悬液(ml) | 0.12.4-2.5 | 0.22.3-2.5 | 0.32.2-2.5 | 0.42.1-2.5 | 0.52.0-2.5 | -2.5-2.5 | --2.52.5 |
Claims (10)
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104322588A (zh) * | 2014-09-16 | 2015-02-04 | 江阴延利汽车饰件股份有限公司 | 一种汽车内用消毒剂 |
CN105287732A (zh) * | 2015-11-25 | 2016-02-03 | 四川农业大学 | 一种治疗胃溃疡的药物配方及其制备方法 |
CN106389701A (zh) * | 2016-12-09 | 2017-02-15 | 界首市昌盛养殖专业合作社 | 一种鸭坏死性肠炎的治疗方法 |
CN106806360A (zh) * | 2015-12-01 | 2017-06-09 | 北京盈科瑞药物研究院有限公司 | 一种新鱼腥草素钠雾化吸入用溶液制剂及其制备方法 |
CN108743471A (zh) * | 2018-06-25 | 2018-11-06 | 佛山市聚成生化技术研发有限公司 | 一种抗菌消炎护肤霜及其制备方法 |
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CN1066335C (zh) * | 1996-02-14 | 2001-05-30 | 雅安三九药业有限公司 | 一种鱼腥草注射液及其制备方法 |
CN1502342A (zh) * | 2002-11-26 | 2004-06-09 | 李善祥 | 治疗急慢性咽炎的药物 |
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Cited By (6)
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CN104322588A (zh) * | 2014-09-16 | 2015-02-04 | 江阴延利汽车饰件股份有限公司 | 一种汽车内用消毒剂 |
CN104322588B (zh) * | 2014-09-16 | 2016-08-31 | 江阴延利汽车饰件股份有限公司 | 一种汽车内用消毒剂 |
CN105287732A (zh) * | 2015-11-25 | 2016-02-03 | 四川农业大学 | 一种治疗胃溃疡的药物配方及其制备方法 |
CN106806360A (zh) * | 2015-12-01 | 2017-06-09 | 北京盈科瑞药物研究院有限公司 | 一种新鱼腥草素钠雾化吸入用溶液制剂及其制备方法 |
CN106389701A (zh) * | 2016-12-09 | 2017-02-15 | 界首市昌盛养殖专业合作社 | 一种鸭坏死性肠炎的治疗方法 |
CN108743471A (zh) * | 2018-06-25 | 2018-11-06 | 佛山市聚成生化技术研发有限公司 | 一种抗菌消炎护肤霜及其制备方法 |
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