CN1914213B - 噻唑并嘧啶的制备方法 - Google Patents

噻唑并嘧啶的制备方法 Download PDF

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Publication number
CN1914213B
CN1914213B CN2004800414459A CN200480041445A CN1914213B CN 1914213 B CN1914213 B CN 1914213B CN 2004800414459 A CN2004800414459 A CN 2004800414459A CN 200480041445 A CN200480041445 A CN 200480041445A CN 1914213 B CN1914213 B CN 1914213B
Authority
CN
China
Prior art keywords
compound
formula
methyl
difluorophenyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2004800414459A
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English (en)
Chinese (zh)
Other versions
CN1914213A (zh
Inventor
迈克尔·巴特斯
理查德·怀斯戴尔
科林·汤姆森
马修·J·韦尔哈姆
安德鲁·沃茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
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AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1914213A publication Critical patent/CN1914213A/zh
Application granted granted Critical
Publication of CN1914213B publication Critical patent/CN1914213B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
CN2004800414459A 2003-12-05 2004-12-02 噻唑并嘧啶的制备方法 Expired - Fee Related CN1914213B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0328243.1A GB0328243D0 (en) 2003-12-05 2003-12-05 Methods
GB0328243.1 2003-12-05
PCT/GB2004/005072 WO2005056563A2 (en) 2003-12-05 2004-12-02 Process for the preparation of thiazolopyrimidines

Publications (2)

Publication Number Publication Date
CN1914213A CN1914213A (zh) 2007-02-14
CN1914213B true CN1914213B (zh) 2011-05-11

Family

ID=29764654

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2004800414459A Expired - Fee Related CN1914213B (zh) 2003-12-05 2004-12-02 噻唑并嘧啶的制备方法

Country Status (22)

Country Link
US (3) US7790883B2 (enExample)
EP (1) EP1711505B1 (enExample)
JP (1) JP4808629B2 (enExample)
KR (1) KR101170188B1 (enExample)
CN (1) CN1914213B (enExample)
AR (1) AR046750A1 (enExample)
AT (1) ATE471941T1 (enExample)
AU (1) AU2004296241B2 (enExample)
BR (1) BRPI0417300A (enExample)
CA (1) CA2546719A1 (enExample)
DE (1) DE602004027840D1 (enExample)
ES (1) ES2345660T3 (enExample)
GB (1) GB0328243D0 (enExample)
IL (1) IL175743A (enExample)
MY (1) MY143761A (enExample)
NO (1) NO20063111L (enExample)
NZ (2) NZ583012A (enExample)
SG (1) SG149005A1 (enExample)
TW (1) TWI347945B (enExample)
UY (1) UY28651A1 (enExample)
WO (1) WO2005056563A2 (enExample)
ZA (1) ZA200604491B (enExample)

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GB2359551A (en) 2000-02-23 2001-08-29 Astrazeneca Uk Ltd Pharmaceutically active pyrimidine derivatives
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GB0221828D0 (en) 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
GB0221829D0 (en) * 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
GB0328243D0 (en) 2003-12-05 2004-01-07 Astrazeneca Ab Methods
JP6463366B2 (ja) 2013-10-10 2019-01-30 イースタン バージニア メディカル スクール １２−リポキシゲナーゼ阻害物質としての４−（（２−ヒドロキシ−３−メトキシベンジル）アミノ）ベンゼンスルホンアミド誘導体
GB201807898D0 (en) * 2018-05-15 2018-06-27 Kancera Ab New processes and products with increased chiral purity

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WO2002083693A1 (en) * 2001-04-12 2002-10-24 Astrazeneca Ab Thiazolopyrimidines and their use as modulators of chemokine receptor activity
CN1402730A (zh) * 1999-10-01 2003-03-12 阿斯特拉曾尼卡英国有限公司 新的噻唑并(4,5－d)嘧啶化合物

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Also Published As

Publication number Publication date
ATE471941T1 (de) 2010-07-15
US20090043097A1 (en) 2009-02-12
BRPI0417300A (pt) 2007-03-06
EP1711505A2 (en) 2006-10-18
EP1711505B1 (en) 2010-06-23
IL175743A (en) 2011-10-31
KR101170188B1 (ko) 2012-07-31
ES2345660T3 (es) 2010-09-29
JP2007513131A (ja) 2007-05-24
CA2546719A1 (en) 2005-06-23
NZ547685A (en) 2010-02-26
GB0328243D0 (en) 2004-01-07
TW200524945A (en) 2005-08-01
AR046750A1 (es) 2005-12-21
CN1914213A (zh) 2007-02-14
US20070282103A1 (en) 2007-12-06
NO20063111L (no) 2006-09-05
US20100217000A1 (en) 2010-08-26
US7790883B2 (en) 2010-09-07
WO2005056563A3 (en) 2005-08-25
WO2005056563A2 (en) 2005-06-23
AU2004296241A1 (en) 2005-06-23
SG149005A1 (en) 2009-01-29
KR20060118525A (ko) 2006-11-23
ZA200604491B (en) 2007-10-31
MY143761A (en) 2011-07-15
TWI347945B (en) 2011-09-01
DE602004027840D1 (de) 2010-08-05
NZ583012A (en) 2011-08-26
UY28651A1 (es) 2005-07-29
AU2004296241B2 (en) 2009-01-22
JP4808629B2 (ja) 2011-11-02
IL175743A0 (en) 2006-09-05

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Granted publication date: 20110511

Termination date: 20121202