CN1897952A - 中性白细胞增多抑制剂 - Google Patents
中性白细胞增多抑制剂 Download PDFInfo
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- CN1897952A CN1897952A CNA2004800381582A CN200480038158A CN1897952A CN 1897952 A CN1897952 A CN 1897952A CN A2004800381582 A CNA2004800381582 A CN A2004800381582A CN 200480038158 A CN200480038158 A CN 200480038158A CN 1897952 A CN1897952 A CN 1897952A
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- 239000000700 radioactive tracer Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- BTURAGWYSMTVOW-UHFFFAOYSA-M sodium dodecanoate Chemical compound [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 description 1
- 229940082004 sodium laurate Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229940075554 sorbate Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
- 208000005198 spinal stenosis Diseases 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 description 1
- 238000002627 tracheal intubation Methods 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 150000003673 urethanes Chemical class 0.000 description 1
- 230000001196 vasorelaxation Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 239000003871 white petrolatum Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
Claims (5)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP433747/2003 | 2003-12-26 | ||
JP2003433747 | 2003-12-26 | ||
PCT/JP2004/019199 WO2005063250A1 (ja) | 2003-12-26 | 2004-12-22 | 好中球増多抑制剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1897952A true CN1897952A (zh) | 2007-01-17 |
CN1897952B CN1897952B (zh) | 2010-12-08 |
Family
ID=34736527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2004800381582A Expired - Fee Related CN1897952B (zh) | 2003-12-26 | 2004-12-22 | 中性白细胞增多抑制剂 |
Country Status (13)
Country | Link |
---|---|
US (2) | US20070117806A1 (zh) |
EP (1) | EP1698339A4 (zh) |
JP (1) | JP4688681B2 (zh) |
KR (2) | KR101293350B1 (zh) |
CN (1) | CN1897952B (zh) |
AU (1) | AU2004308806B9 (zh) |
BR (1) | BRPI0417200A (zh) |
CA (1) | CA2549672C (zh) |
HK (1) | HK1098378A1 (zh) |
IL (1) | IL176473A (zh) |
RU (1) | RU2356555C2 (zh) |
TW (1) | TW200522962A (zh) |
WO (1) | WO2005063250A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101537006B (zh) * | 2008-03-18 | 2012-06-06 | 中国科学院上海药物研究所 | 哒嗪酮类化合物在制备抗肿瘤药物中的用途 |
CN102133217B (zh) * | 2010-01-27 | 2013-07-24 | 中国科学院上海药物研究所 | 一类以n为桥键的哒嗪酮类化合物在制备抗肿瘤的药物中的用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0482208T3 (da) * | 1990-04-25 | 2000-09-18 | Nissan Chemical Ind Ltd | Pyridazinonderivat |
IL112695A (en) * | 1994-02-22 | 1999-04-11 | Green Cross Corp | Pharmaceutical compositions containing pyridazinone derivatives |
EP1025847B1 (en) * | 1997-08-28 | 2005-10-26 | Nissan Chemical Industries, Ltd. | Neovascularization promoters and neovascularization potentiators |
US6037346A (en) * | 1997-10-28 | 2000-03-14 | Vivus, Inc. | Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
CN1137686C (zh) * | 1998-09-01 | 2004-02-11 | 日产化学工业株式会社 | 椎管狭窄的治疗药 |
EP1157694A4 (en) * | 1998-12-07 | 2002-08-28 | Nissan Chemical Ind Ltd | REMEDIES OF THE ERECTIONAL DISORDER |
JP2001131088A (ja) * | 1999-11-02 | 2001-05-15 | Kyurin:Kk | シンドロームx症候群治療剤 |
-
2004
- 2004-12-22 BR BRPI0417200-0A patent/BRPI0417200A/pt not_active Application Discontinuation
- 2004-12-22 CN CN2004800381582A patent/CN1897952B/zh not_active Expired - Fee Related
- 2004-12-22 JP JP2005516599A patent/JP4688681B2/ja not_active Expired - Fee Related
- 2004-12-22 EP EP04807556A patent/EP1698339A4/en not_active Withdrawn
- 2004-12-22 WO PCT/JP2004/019199 patent/WO2005063250A1/ja active Application Filing
- 2004-12-22 KR KR1020097027323A patent/KR101293350B1/ko not_active IP Right Cessation
- 2004-12-22 AU AU2004308806A patent/AU2004308806B9/en not_active Ceased
- 2004-12-22 RU RU2006127040/15A patent/RU2356555C2/ru not_active IP Right Cessation
- 2004-12-22 KR KR1020067012723A patent/KR20060125816A/ko not_active Application Discontinuation
- 2004-12-22 CA CA2549672A patent/CA2549672C/en not_active Expired - Fee Related
- 2004-12-22 US US10/584,222 patent/US20070117806A1/en not_active Abandoned
- 2004-12-24 TW TW093140627A patent/TW200522962A/zh not_active IP Right Cessation
-
2006
- 2006-06-21 IL IL176473A patent/IL176473A/en not_active IP Right Cessation
-
2007
- 2007-05-09 HK HK07104941.5A patent/HK1098378A1/xx not_active IP Right Cessation
-
2008
- 2008-08-08 US US12/188,638 patent/US20080306080A1/en not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101537006B (zh) * | 2008-03-18 | 2012-06-06 | 中国科学院上海药物研究所 | 哒嗪酮类化合物在制备抗肿瘤药物中的用途 |
CN102133217B (zh) * | 2010-01-27 | 2013-07-24 | 中国科学院上海药物研究所 | 一类以n为桥键的哒嗪酮类化合物在制备抗肿瘤的药物中的用途 |
Also Published As
Publication number | Publication date |
---|---|
WO2005063250A1 (ja) | 2005-07-14 |
AU2004308806B9 (en) | 2010-01-28 |
TW200522962A (en) | 2005-07-16 |
KR20100019542A (ko) | 2010-02-18 |
JP4688681B2 (ja) | 2011-05-25 |
AU2004308806A1 (en) | 2005-07-14 |
CA2549672C (en) | 2010-06-22 |
IL176473A (en) | 2013-06-27 |
TWI341729B (zh) | 2011-05-11 |
KR101293350B1 (ko) | 2013-08-05 |
KR20060125816A (ko) | 2006-12-06 |
BRPI0417200A (pt) | 2007-02-06 |
EP1698339A4 (en) | 2009-06-17 |
EP1698339A1 (en) | 2006-09-06 |
HK1098378A1 (en) | 2007-07-20 |
US20070117806A1 (en) | 2007-05-24 |
RU2006127040A (ru) | 2008-02-10 |
RU2356555C2 (ru) | 2009-05-27 |
IL176473A0 (en) | 2006-10-05 |
US20080306080A1 (en) | 2008-12-11 |
JPWO2005063250A1 (ja) | 2007-07-19 |
CN1897952B (zh) | 2010-12-08 |
CA2549672A1 (en) | 2005-07-14 |
AU2004308806B2 (en) | 2009-10-29 |
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