CN1883610A - Chinese animal medicine for treating birds viral disease and method for preparing same - Google Patents
Chinese animal medicine for treating birds viral disease and method for preparing same Download PDFInfo
- Publication number
- CN1883610A CN1883610A CN 200610013792 CN200610013792A CN1883610A CN 1883610 A CN1883610 A CN 1883610A CN 200610013792 CN200610013792 CN 200610013792 CN 200610013792 A CN200610013792 A CN 200610013792A CN 1883610 A CN1883610 A CN 1883610A
- Authority
- CN
- China
- Prior art keywords
- radix
- raw material
- parts
- treatment
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a Chinese preparation for treating bird virus diseases and process for preparation, wherein the medicament is prepared from the following raw materials (by weight ratio): honeysuckle flower 2-6 parts, baikal skullcap root 3-10 parts, capsule of weeping forsythia 5-15 parts, astragalus root 2-6 parts, kuh-seng 2-6 parts, bistorta 2-6 parts, licorice root 2-6 parts, yellow corktree bark 1-5 part, and dried rehmannia root 2-8 parts.
Description
Technical field
The present invention relates to herbal medicine of a kind of treatment birds diseases such as (chicken, duck, goose, Columba livias) and preparation method thereof, particularly a kind of herbal medicine for the treatment of avian viral diseases and preparation method thereof.
Background technology
Along with the development of society and the change of prosperity of economy and human health idea, the idea of back to nature, the harmony between man and nature is more and more praised highly." dining table safely " received great concern, and people are also more and more high to the requirement of safe diet.The abuse of Western medicine has brought great diet hidden danger to livestock product is edible, and drug residue has become one of principal element that influences livestock product safety.The Ministry of Agriculture has successively put into effect a series of bulletin, abrogated the application of some antiviral drugs on livestock product successively, and the use of vaccine disease preventing and treating completely, so how to prevent and treat the great difficult problem that viral disease has become aquaculture to face at present to need to be resolved hurrily.As newcastle disease is a kind of hyperinfection disease that is caused by virus, and this disease is that harm is very serious a kind of in the fowl disease, and mortality rate is very high, causes than the large economy loss, does not still have special effect medicine therapeutic at present.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, providing a kind of is composition with the pure natural herbal medicine, improves therapeutic effect, reduces herbal medicine of the treatment avian viral diseases for the treatment of cost and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object:
A kind of herbal medicine for the treatment of avian viral diseases, its feature is formed by following portions by weight proportion raw material mixed preparing: Flos Lonicerae 2-6 part, Radix Scutellariae 3-10 part, Fructus Forsythiae 5-15 part, Radix Astragali 2-6 part, Radix Sophorae Flavescentis 2-6 part, Rhizoma Bistortae 2-6 part, Radix Glycyrrhizae 2-6 part, Cortex Phellodendri 1-5 part, Radix Rehmanniae 2-8 part.
A kind of preparation method for the treatment of the herbal medicine of avian viral diseases is characterized in that carrying out as follows:
(1) takes off and state the parts by weight proportion raw material: Flos Lonicerae 2-6 part, Radix Scutellariae 3-10 part, Fructus Forsythiae 5-15 part, Radix Astragali 2-6 part, Radix Sophorae Flavescentis 2-6 part, Rhizoma Bistortae 2-6 part, Radix Glycyrrhizae 2-6 part, Cortex Phellodendri 1-5 part, Radix Rehmanniae 2-8 part;
(2) rinsing drying: routinely that above-mentioned various raw material rinsings are clean, it is kept dry in temperature 60-120 ℃, time 1-2 hour;
(3) crushing screening:, cross sieve 2-4 number with raw material pulverizing;
(4) soak into extraction: the raw material after the pulverizing soaked in solvent 2-4 hour, and quantity of solvent is 2-3 a times of raw material total amount, and the solvent of selecting for use is a purified water;
(5) pressurization percolation: adopt pressurization percolation method extraction fast, the time is 1.5-2 hour, and pressure limit is 100-200pa;
(6) flocculating sedimentation: the flocculating setting agent of employing is the ZTC1-1 natural clarifying agent, and the flocculating setting agent adding proportion is the 0.5-1% of extract total amount;
(7) filter: adopt ultrafiltration membrance filter, cross 200-350 purpose film, remove destarching, protein, resin, tannin impurity.
(8) concentrate: the evaporation precipitation concentrates in the ratio that every 100kg medical material goes out the 100L medicinal liquid.
This extract drugs adopts high pressure, quick, circulatory displacement method.When the evaporation precipitation gets concentrate, under vacuum state, in regulating the suction vaporization chamber, the influencing meridian effusion meter concentrates.The evaporation gas cools off to flow to through high-performance heat exchanger and reclaimed by flow container, basin before solvent pump is input to extractor again.Can enter fresh solvent continuously, discharge extractum continuously, obtain concentrate continuously, the leaching medical material that so moves in circles, solvent adopts purified water.
Separate natural clarifying agents such as adopting ZTC1-1, it is very effective to remove impurity such as shallow lake, protein, resin, tannin, and effective ingredient or effective site are not almost had influence.Adopt ultrafiltration membrance filter, have characteristics such as to add chemical reagent, mild condition, no composition destruction, flow process weak point.
This medicament composing prescription compiles monarch, minister, helps, makes, and fully worships the principle of Chinese medicine " organic conception " and " dialectical executing controlled ", the treating both the principal and secondary aspects of a disease function of performance Chinese medicine, and its concrete function is summarized as follows with curing mainly:
The extraction process of uses advanced is separated effective monomer in the medical material, can effectively keep the effective ingredient in the Chinese herbal medicine, and be rich in several amino acids and trace element, does not have organic solvent residual in the extract.The effective ingredient that extracts in the prescription is the formation of blocking virus nucleic acid directly, suppress duplicating and breeding of virus, but and the humoral immunization of enhancing body and cellular immunization, induce body to produce interferon, enhancing antibody forms, strengthen the phagocytosis of macrophage, thereby effectively kill pathogen pathogen.
The invention has the beneficial effects as follows: this medicine belongs to pure Chinese medicinal preparation, has certain two-ways regulation body's immunological function, for the control of chicken viral diseases provides new way.This products material all derives from natural Chinese medicine, and the treatment theory is at current direct killing action to pathogen, reaches the viricidal effect that presses down by transferring the intrinsic antipathogen mechanism of body (as immune system, complement system etc.) simultaneously.Medicine green natural, noresidue endanger, and meet the theory of green health.Medicine of the present invention is primarily aimed at the gal virus disease, especially to the prevention of newcastle with treatment has and significant advantage.Studies confirm that medicine of the present invention is external has direct inhibitory or killing effect to Avian pneumo-encephalitis virus; Model to artificial challenge's Avian pneumo-encephalitis virus also has significant protection and therapeutical effect, and preceding 3 days of viral infection and infection administration simultaneously curative effect are better than infecting administration in back three days.Clinical research confirmation medicine of the present invention has excellent curative to newcastle, especially can remove heating that viral infection causes rapidly, improve symptom, promote sick fowl to recover to search for food, promote laying rate and egg product matter to recover, second day clinical symptoms alleviated rapidly after the general medication, recovery from illness in 3～5 days, the Chinese medicine oral liquid that is better than general extraction process evident in efficacy.
The heat-clearing and toxic substances removing ability of this medicine is strong, the clinical viral diseases such as treatment poultry infectious bursal disease, atypical newcastle disease, infectious bronchitis that are mainly used in.Prescription is suitable, and the variation of heat clearing away approach has taken into full account the thermotaxic characteristics of poultry, and the pestilence of dispelling the heat, dispel alleviates the sense of discomfort of body, thereby alleviates the symptom of disease to a great extent, increases disease fowl appetite, promotes the rehabilitation of disease fowl.The various effective ingredient of choosing are reasonably combined, and the raw material sources that adopted are extensive, and preparation technology is simple, can prevent and treat viral disease and syndrome thereof that fowl poultry kind is often sent out safely and effectively.This medicine is drug residue free in use, has no side effect, and is little to the body zest, is difficult for producing drug resistance, solved the puzzlement of outlet restriction fully.This cured substance rate height, production cost is low, applied range.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of herbal medicine for the treatment of avian viral diseases, its feature is formed by the various raw material mixed preparing of following weight: Flos Lonicerae 4kg, Radix Scutellariae 6.5kg, Fructus Forsythiae 10kg, Radix Astragali 4kg, Radix Sophorae Flavescentis 4kg, Rhizoma Bistortae 4kg, Radix Glycyrrhizae 4kg, Cortex Phellodendri 3kg, Radix Rehmanniae 5kg.
A kind of preparation method for the treatment of the herbal medicine of avian viral diseases is characterized in that carrying out as follows:
(1) takes off the various raw materials of stating weight: Flos Lonicerae 4kg, Radix Scutellariae 6.5kg, Fructus Forsythiae 10kg, Radix Astragali 4kg, Radix Sophorae Flavescentis 4kg, Rhizoma Bistortae 4kg, Radix Glycyrrhizae 4kg, Cortex Phellodendri 3kg, Radix Rehmanniae 5kg;
(2) rinsing drying: routinely that above-mentioned various raw material rinsings are clean, it is kept dry in temperature 60-120 ℃, time 1-2 hour;
(3) crushing screening: can adopt Universalpulverizer with raw material pulverizing, cross sieve 2-4 number, (being the 20-40 mesh sieve);
(4) soak into extraction: the raw material after the pulverizing soaked in solvent 2-4 hour, and quantity of solvent is 2-3 a times of raw material total amount, and the solvent of selecting for use is a purified water;
(5) pressurization percolation: adopt pressurization percolation method extraction fast, the time is 1.5-2 hour, and pressure limit is 100pa-200pa;
(6) flocculating sedimentation: the flocculating setting agent of employing is the ZTC1-1 natural clarifying agent, and the flocculating setting agent adding proportion is the 0.5-1% of extract total amount;
(7) filter: adopt ultrafiltration membrance filter, cross 200-350 purpose film, remove impurity such as destarching, protein, resin, tannin.
(8) concentrate: the evaporation precipitation concentrates in the ratio that every 100kg medical material goes out the 100L medicinal liquid.
Embodiment 2
A kind of herbal medicine for the treatment of avian viral diseases, its feature is formed by the various raw material mixed preparing of following weight: Flos Lonicerae 2kg, Radix Scutellariae 3kg, Fructus Forsythiae 5kg, Radix Astragali 2kg, Radix Sophorae Flavescentis 2kg, Rhizoma Bistortae 2kg, Radix Glycyrrhizae 2kg, Cortex Phellodendri 1kg, Radix Rehmanniae 2kg.
A kind of preparation method for the treatment of the herbal medicine of avian viral disease is characterized in that carrying out as follows:
Take off the various raw materials of stating weight: Flos Lonicerae 2kg, Radix Scutellariae 3kg, Fructus Forsythiae 5kg, Radix Astragali 2kg, Radix Sophorae Flavescentis 2kg, Rhizoma Bistortae 2kg, Radix Glycyrrhizae 2kg, Cortex Phellodendri 1kg, Radix Rehmanniae 2kg;
Carry out rinsing drying, crushing screening, infiltration extraction, pressurization percolation, flocculating sedimentation, filtration successively, concentrate.Implement concrete steps and condition with embodiment 1.
Embodiment 3
A kind of herbal medicine for the treatment of avian viral diseases, its feature is formed by the various raw material mixed preparing of following weight: Flos Lonicerae 6kg, Radix Scutellariae 10kg, Fructus Forsythiae 15kg, Radix Astragali 6kg, Radix Sophorae Flavescentis 6kg, Rhizoma Bistortae 6kg, Radix Glycyrrhizae 6kg, Cortex Phellodendri 5kg, Radix Rehmanniae 8kg.
A kind of preparation method for the treatment of the herbal medicine of avian viral disease is characterized in that carrying out as follows:
Take off the various raw materials of stating weight: Flos Lonicerae 6kg, Radix Scutellariae 10kg, Fructus Forsythiae 15kg, Radix Astragali 6kg, Radix Sophorae Flavescentis 6kg, Rhizoma Bistortae 6kg, Radix Glycyrrhizae 6kg, Cortex Phellodendri 5kg, Radix Rehmanniae 8kg;
Carry out rinsing drying, crushing screening, infiltration extraction, pressurization percolation, flocculating sedimentation, filtration successively, concentrate.Implement concrete steps and condition with embodiment 1.
The medication effect:
Compare experiment with 150 30 age in days broiler (aseptic through physical examination) through behind the artificial counteracting toxic substances, the result shows that adopting the present invention to treat chicken viral diseases has tangible curative effect.
Experimental result is as follows:
| Numbering | Group | Mortality rate % | Cure rate % | Effective percentage % |
| A | Positive controls | 96.9 | - | - |
| B | Healthy group | 0 | - | - |
| C | The prevention group | 0(0/30) | 75(22/30) | 86.7(26/30) |
| D | The treatment group | 0(0/30) | 90(27/30) | 95(28.5/30) |
| E | " antipyretic and antitoxic powder " | 0(0/30) | 78(22/30) | 86.7(26/30) |
This result of the test shows, prevention group chicken whole mental status behind counteracting toxic substances is better, symptom evening appears, and symptom is obviously light than other two counteracting toxic substances groups, sickness rate is also low, analyzes prevention group and matched group difference highly significant (P＜0.01) by statistics, treatment group and matched group significant difference (P＜0.05) illustrate that the newcastle that the present invention causes virus has significant prevention and therapeutical effect.And with antipyretic and antitoxic powder " group weak curative effect similarities and differences sample remarkable (≤0.01).
Application example:
In December, 2005, the laying hen that culture in each county, east, Shijiazhuang, same symptoms appears successively: swollen eye socket, cough, snore, the reduction of searching for food, laying rate descends, December 20 days finds that with the family of raising chickens, rear section the chicken death rate rises, and dead fast, feed intake descends fast, 10-20 of per 1000 chickens death every day, dead about 60/day of the most serious family.It is dead to drink the aggravation of IV system.
At above-mentioned phenomenon, use medicine of the present invention, cooperate control death rapidly such as multidimensional electrolyte in addition, the chicken group recovers the good mental status.
Analyze: the most follicle of the dead chicken of inspection is out of shape through cuing open, intestinal mucosa is extensively hemorrhage, egg peritonitis, blue, the glandular stomach nipple petechial hemorrhage of cockscomb, mucosal bleeding under indivedual muscular stomach cutin membranes, cecal tonsil and following 3-5cm place small intestinal thereof have ulcer kitchen range, petechia.Be diagnosed as doubtful newcastle.
Sum up: similar symptom, early find early treatment, if use vaccine NDIV system drinking-water can cause mortality, adopt the present invention of Chinese herbal and crude drugs preparations, add antimicrobial drug bacillus KUAIKE or just safe glad control secondary infection in the water simultaneously; Facts have proved that curative effect of medication of the present invention is remarkable; Expectant treatment is the may command state of an illness also, reduces mortality rate.
Above-mentioned detailed description of the herbal medicine and preparation method thereof of treatment avian viral diseases being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (2)
1, a kind of herbal medicine for the treatment of avian viral diseases, its feature is formed by following portions by weight proportion raw material mixed preparing: Flos Lonicerae 2-6 part, Radix Scutellariae 3-10 part, Fructus Forsythiae 5-15 part, Radix Astragali 2-6 part, Radix Sophorae Flavescentis 2-6 part, Rhizoma Bistortae 2-6 part, Radix Glycyrrhizae 2-6 part, Cortex Phellodendri 1-5 part, Radix Rehmanniae 2-8 part.
2, a kind of preparation method for the treatment of the herbal medicine of avian viral diseases is characterized in that carrying out as follows:
(1) takes off and state the parts by weight proportion raw material: Flos Lonicerae 2-6 part, Radix Scutellariae 3-10 part, Fructus Forsythiae 5-15 part, Radix Astragali 2-6 part, Radix Sophorae Flavescentis 2-6 part, Rhizoma Bistortae 2-6 part, Radix Glycyrrhizae 2-6 part, Cortex Phellodendri 1-5 part, Radix Rehmanniae 2-8 part;
(2) rinsing drying: routinely that above-mentioned various raw material rinsings are clean, it is kept dry in temperature 60-120 ℃, time 1-2 hour;
(3) crushing screening:, cross sieve 2-4 number with raw material pulverizing;
(4) soak into extraction: the raw material after the pulverizing soaked in solvent 2-4 hour, and quantity of solvent is 2-3 a times of raw material total amount, and the solvent of selecting for use is a purified water;
(5) pressurization percolation: adopt pressurization percolation method extraction fast, the time is 1.5-2 hour, and pressure limit is 100-200pa;
(6) flocculating sedimentation: the flocculating setting agent of employing is the ZTC1-1 natural clarifying agent, and the flocculating setting agent adding proportion is the 0.5-1% of extract total amount;
(7) filter: adopt ultrafiltration membrance filter, cross 200-350 purpose film, remove destarching, protein, resin, tannin impurity.
(8) concentrate: the evaporation precipitation concentrates in the ratio that every 100kg medical material goes out the 100L medicinal liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006100137921A CN1883610B (en) | 2006-05-19 | 2006-05-19 | Chinese animal medicine for treating birds viral disease and method for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006100137921A CN1883610B (en) | 2006-05-19 | 2006-05-19 | Chinese animal medicine for treating birds viral disease and method for preparing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1883610A true CN1883610A (en) | 2006-12-27 |
| CN1883610B CN1883610B (en) | 2011-11-02 |
Family
ID=37581993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006100137921A Expired - Fee Related CN1883610B (en) | 2006-05-19 | 2006-05-19 | Chinese animal medicine for treating birds viral disease and method for preparing same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1883610B (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101569707B (en) * | 2009-06-11 | 2011-06-01 | 中国农业科学院兰州畜牧与兽药研究所 | Drug for controlling bursa of Fabricius in poultry |
| CN102228679A (en) * | 2011-06-15 | 2011-11-02 | 山东华辰生物科技有限公司 | Chicken interferon gamma combined medicament and application |
| CN103768234A (en) * | 2012-10-24 | 2014-05-07 | 天津中敖生物科技有限公司 | Traditional Chinese medicine composition for treating chicken infectious bursa of fabricius and preparation method of traditional Chinese medicine composition |
| CN104644962A (en) * | 2013-11-21 | 2015-05-27 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition for treating infectious bursal disease of chicken and preparation method thereof |
| CN113786466A (en) * | 2021-10-11 | 2021-12-14 | 甘肃省畜牧兽医研究所 | Compound Chinese herbal medicine for chicken respiratory diseases and preparation method thereof |
| CN114886987A (en) * | 2021-06-26 | 2022-08-12 | 临沂金翠兽药有限公司 | Composition for relieving poultry bronchitis and preparation method and use method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1186061C (en) * | 2002-09-27 | 2005-01-26 | 长春市动物药厂 | Extracted herbal medicine for treating chicken infectious bursa of Fabricius |
| CN1241608C (en) * | 2002-09-27 | 2006-02-15 | 长春市动物药厂 | Antiviral, antibacterial and antiinflammatory herbal injection for treating livestock and fowl infectious disease |
-
2006
- 2006-05-19 CN CN2006100137921A patent/CN1883610B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101569707B (en) * | 2009-06-11 | 2011-06-01 | 中国农业科学院兰州畜牧与兽药研究所 | Drug for controlling bursa of Fabricius in poultry |
| CN102228679A (en) * | 2011-06-15 | 2011-11-02 | 山东华辰生物科技有限公司 | Chicken interferon gamma combined medicament and application |
| CN103768234A (en) * | 2012-10-24 | 2014-05-07 | 天津中敖生物科技有限公司 | Traditional Chinese medicine composition for treating chicken infectious bursa of fabricius and preparation method of traditional Chinese medicine composition |
| CN104644962A (en) * | 2013-11-21 | 2015-05-27 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition for treating infectious bursal disease of chicken and preparation method thereof |
| CN114886987A (en) * | 2021-06-26 | 2022-08-12 | 临沂金翠兽药有限公司 | Composition for relieving poultry bronchitis and preparation method and use method thereof |
| CN113786466A (en) * | 2021-10-11 | 2021-12-14 | 甘肃省畜牧兽医研究所 | Compound Chinese herbal medicine for chicken respiratory diseases and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1883610B (en) | 2011-11-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100337651C (en) | Chinese medicine composition for preventing bird flu | |
| CN1879745A (en) | A veterinary Chinese medicinal powder for treating avian viral disease | |
| CN1883610B (en) | Chinese animal medicine for treating birds viral disease and method for preparing same | |
| CN101259160B (en) | Compound preparations for treating birdsvirosis and preparation thereof | |
| CN1879686A (en) | A Chinese medicinal composition for treating avian viral disease and preparation method thereof | |
| CN104887890A (en) | Medicine composition for treating white scour of chicken and preparation method thereof | |
| CN104398612B (en) | Traditional Chinese medicine composition for treating chicken coccidiosis and preparation method thereof | |
| CN1330330C (en) | Antivirus medicinal composition, preparation method and use | |
| CN104771686B (en) | A kind of Chinese medicine preparation for treating poultry ventriculitis proventriculitis and preparation method thereof | |
| CN103285255B (en) | Anti-coccidiosis pharmaceutical composition as well as preparation method and use thereof | |
| CN109306009B (en) | Preparation method of anti-piglet toxigenic escherichia coli egg yolk antibody | |
| CN110680902A (en) | Traditional Chinese medicine composition for treating laying hen fatty liver | |
| CN109432287B (en) | Traditional Chinese medicine oral liquid for preventing and treating excessive heat syndrome of poultry qi system and preparation method thereof | |
| CN104840591A (en) | Traditional Chinese medicine composition with effect of preventing and treating Newcastle disease | |
| CN1895422A (en) | Chinese animal medicinal composition for treating fowl colibacillus and its making method | |
| CN105560444A (en) | Tibetan drug composition for treating yak gastroenteritis and preparation method and application thereof | |
| CN105147904A (en) | Drug preventing and curing fish red skin disease | |
| CN104784327A (en) | Traditional Chinese veterinary medicine composition for treating respiratory diseases of chicken and preparation method thereof | |
| CN101559105A (en) | Composite for curing viral diseases of birds and preparation method thereof | |
| CN1314421C (en) | Cordate houttuynia mixture for preventing and treating livestock bird infectious disease | |
| CN108514622A (en) | A kind of Chinese medicine preparation and preparation method thereof for treating poultry ventriculitis proventriculitis | |
| CN101947305A (en) | Traditional Chinese medicinal composition for treating virus disease and Escherichia coli mixed infection of poultry | |
| CN102648951A (en) | Traditional Chinese herbal medicament for treating laying hen and broiler chicken newcastle diseases | |
| CN1352966A (en) | Medicine for treating tracheitis and asthma | |
| CN105477312B (en) | The Chinese medicine composition for treating chicken colibacillosis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: TIANJIN HYNARD ANIMAL PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: TIANJIN SHENGJI GROUP CO., LTD. Effective date: 20121016 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 301609 JINGHAI, TIANJIN TO: 300385 XIQING, TIANJIN |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20121016 Address after: Xiaoyuan Tianjin Development Zone 300385 Microelectronics Industrial Zone No. 3 standard factory building B Patentee after: Tianjin Hynard Animal Pharmaceutical Co., Ltd. Address before: 301609. 2, Tianyu Science Park, Jinghai, Tianjin Patentee before: Tianjin Shengji Group Co., Ltd. |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111102 Termination date: 20160519 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |