CN1874781B - 用于癌症治疗的植物提取物的组合物 - Google Patents

用于癌症治疗的植物提取物的组合物 Download PDF

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Publication number
CN1874781B
CN1874781B CN2004800317919A CN200480031791A CN1874781B CN 1874781 B CN1874781 B CN 1874781B CN 2004800317919 A CN2004800317919 A CN 2004800317919A CN 200480031791 A CN200480031791 A CN 200480031791A CN 1874781 B CN1874781 B CN 1874781B
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extract
use according
cancer
composition
cox
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Chinese (zh)
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CN1874781A (zh
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J·道
T·C·S·道
D·D·佟
L·威尔森
M·A·乔丹
W·格尔维克
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Genyous Biomed International Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CN2004800317919A 2003-09-08 2004-09-08 用于癌症治疗的植物提取物的组合物 Expired - Fee Related CN1874781B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50145603P 2003-09-08 2003-09-08
US60/501,456 2003-09-08
PCT/US2004/029263 WO2005044182A2 (en) 2003-09-08 2004-09-08 Compositions of botanical extracts for cancer therapy

Publications (2)

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CN1874781A CN1874781A (zh) 2006-12-06
CN1874781B true CN1874781B (zh) 2010-11-10

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US (2) US8173177B2 (enExample)
EP (1) EP1663103B1 (enExample)
JP (2) JP5300195B2 (enExample)
CN (1) CN1874781B (enExample)
AT (1) ATE532525T1 (enExample)
AU (1) AU2004287358A1 (enExample)
CA (1) CA2538218C (enExample)
DK (1) DK1663103T3 (enExample)
ES (1) ES2373663T3 (enExample)
PL (1) PL1663103T3 (enExample)
RU (1) RU2006111441A (enExample)
WO (1) WO2005044182A2 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1663103T3 (pl) 2003-09-08 2012-05-31 Genyous Biomed Int Inc Kompozycje roślinnych ekstraktów do leczenia nowotworu
SG149053A1 (en) * 2003-09-22 2009-01-29 Genyous Biomed Internat Inc Hippophae rhamnoides compositions for cancer therapy
US20050196409A1 (en) * 2003-09-24 2005-09-08 James Dao Compositions of botanical extracts for treating malignancy-associated changes
JP4789082B2 (ja) * 2004-03-04 2011-10-05 学校法人日本大学 沙棘枝から抽出したエキス並びにそれを含む発ガン抑制剤及び健康食品
US7514085B2 (en) 2004-07-16 2009-04-07 Medimush A/S Immune modulating compounds from fungi
WO2006007848A2 (en) * 2004-07-16 2006-01-26 Medimush A/S Immune modulating compounds from fungi
US20060134243A1 (en) * 2004-12-17 2006-06-22 Bionovo, Inc. Method of using extracts of epimedium species
US7482029B2 (en) 2005-04-01 2009-01-27 Bionovo, Inc. Composition for treatment of menopause
WO2006122274A2 (en) * 2005-05-11 2006-11-16 Baystate Health Systems, Inc. Pharmaceutical formulations of rhodiola crenulata and methods of use thereof
US20060269567A1 (en) * 2005-05-16 2006-11-30 Liu Yuen Universal detoxifying composition
JP2006342103A (ja) * 2005-06-09 2006-12-21 National Cancer Center-Japan ウーロン茶葉抽出物ｏｔａｃを有効成分とする発癌抑制剤
EP1896600A2 (en) * 2005-06-15 2008-03-12 Medimush A/S Anti-cancer combination treatment and kit-of-part
US20090156611A1 (en) * 2005-11-11 2009-06-18 Licentia Ltd. Mammalian hedgehog signaling modulators
US7700136B2 (en) * 2005-11-14 2010-04-20 Bionovo, Inc. Scutellaria barbata extract for the treatment of cancer
WO2007131034A1 (en) * 2006-05-03 2007-11-15 The Regents Of The University Of Michigan Pyrimidone derivatives which are modulators of heat shock protein (hsp) 70
US20110117121A1 (en) * 2006-10-27 2011-05-19 James Dao Compositions for treatment and inhibition of pain
US20090042818A1 (en) * 2007-06-22 2009-02-12 Bionovo, Inc. Liquiritigenin and Derivatives as Selective Estrogen Receptor Beta Agonists
US20080319051A1 (en) * 2007-06-22 2008-12-25 Bionovo, Inc. Liquiritigenin and derivatives as selective estrogen receptor beta agonists
US8221803B1 (en) 2007-06-25 2012-07-17 OncoNatural Solutions, Inc. Composition for prostate health
CA2696304A1 (en) * 2007-08-08 2009-02-12 Bionovo, Inc. Estrogenic extracts of ligustrum lucidum ait. of the oleaceae family and uses thereof
AU2008296076A1 (en) * 2007-09-07 2009-03-12 Bionovo, Inc. Estrogenic extracts of Pueraria lobata Willd, Ohwi of the Leguminosae family and uses thereof
JP2010538093A (ja) 2007-09-07 2010-12-09 バイオノボ・インコーポレーテッド シソ科ファミリーのセイタカナミキソウのエストロゲン性抽出物およびその使用
EP2194998A4 (en) 2007-09-07 2012-03-21 Bionovo Inc STROGENIC EXTRACTS OF ASPARAGUS CONCHINCHINENSIS (LOUR.) MERR OF THE LILIACEAE FAMILY AND USES THEREOF
US20090068298A1 (en) * 2007-09-07 2009-03-12 Bionovo, Inc. ESTROGENIC EXTRACTS OF Astragalus membranaceus Fisch. Bge. Var. mongolicus Bge. of the Leguminosae Family AND USES THEREOF
AU2008326429A1 (en) * 2007-11-19 2009-05-28 Bionovo, Inc. Anti-cancer therapy with an extract of scutellaria barbata
AU2008326431A1 (en) * 2007-11-19 2009-05-28 Bionovo, Inc. Scutellaria barbata extract and combinations for the treatment of cancer
JP2011503237A (ja) * 2007-11-19 2011-01-27 バイオノボ・インコーポレーテッド Ｓｃｕｔｅｌｌａｒｉａｂａｒｂａｔａｄ．ｄｏｎの精製抽出物を作製するためのプロセス
US8512961B2 (en) * 2007-11-19 2013-08-20 Bionovo, Inc. Methods of detecting and treatment of cancers using Scutellaria barbata extract
US20090258942A1 (en) * 2008-04-14 2009-10-15 Bionovo, Inc. Calycosin and analogs thereof for the treatment of estrogen receptor beta-mediated diseases
WO2009137534A2 (en) * 2008-05-06 2009-11-12 Bionovo, Inc. Estrogenic extracts for use in treating vaginal and vulvar atrophy
CA2726982A1 (en) * 2008-06-05 2009-12-10 Bionovo, Inc. Method of quantification of multiple bioactives from botanical compositions
WO2009148620A2 (en) * 2008-06-06 2009-12-10 Bionovo, Inc. Anthraquinones and analogs from rhuem palmatum for treatment of estrogen receptor beta-mediated conditions
WO2010028187A2 (en) * 2008-09-03 2010-03-11 Bionovo, Inc. Methods and compositions for the treatment of cancer
JP2012525412A (ja) * 2009-04-28 2012-10-22 バイオノボ・インコーポレーテッド 脂肪蓄積を減少させ、体重減少を誘導する方法
TWI606835B (zh) * 2010-04-23 2017-12-01 中央研究院 基於靈芝多醣之組合物及治療癌症之方法
EP2635127B1 (en) * 2010-11-04 2018-10-17 Genyous Biomed International Combination therapy for prostate cancer using botanical compositions and bicalutamide
US8858953B2 (en) * 2011-05-09 2014-10-14 Yu-Hwa Peter Sheng Herbal composition for treating cancer
US8765193B2 (en) * 2012-02-24 2014-07-01 Santé International, Inc. Methods for radiation protection
JP6093238B2 (ja) * 2013-05-13 2017-03-08 株式会社リンクス 放射線障害に対する造血前駆細胞回復剤
CA2951110A1 (en) 2013-06-03 2014-12-11 Genyous Biomed International Combination therapy for prostate cancer using botanical compositions and docetaxel
CA2953283A1 (en) * 2013-06-03 2014-12-11 Genyous Biomed International Novel formulations of botanical extracts for cancer therapy
US9789153B2 (en) 2014-07-02 2017-10-17 Hsiu-Hsien Tsai Composition for preventing cancer and treating cancer and intensifying the effects of other anticancer drugs
US20170035789A1 (en) * 2015-08-05 2017-02-09 Bill H. McAnalley Composition Of Dietary Supplements Based On Apoptosis that Support Optimal Health
KR101951203B1 (ko) * 2015-09-24 2019-02-25 주식회사 씨엔에이치코퍼레이션 생약 성분을 포함하는 호흡기암 예방 또는 치료용 조성물
CN110122232B (zh) * 2018-02-09 2022-08-05 紫云自治县长萌农业科技开发有限责任公司 一种提高山豆根种子坐果率和产量的栽培方法
WO2022097794A1 (ko) * 2020-11-09 2022-05-12 경희대학교 산학협력단 단삼 및 대황의 복합추출물을 포함하는 악액질 예방 또는 치료용 조성물
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CN113633732A (zh) * 2021-09-28 2021-11-12 山东大学 一种治疗肺癌的中药组合物及其制备方法和应用
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1110571A (zh) * 1994-04-27 1995-10-25 周纯喜 一种抗癌治癌药物及其生产工艺
KR20020078314A (ko) * 2001-04-09 2002-10-18 조갑환 동/식물의 약재를 이용한 건강식품 제조방법
CN1413657A (zh) * 2002-10-17 2003-04-30 王长奎 一种治疗肝癌中药胶囊、药丸及制备方法
CN1436564A (zh) * 2002-12-17 2003-08-20 李天德 治疗肝癌的药物及制备方法

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU577036A1 (ru) * 1974-09-16 1977-10-25 Ростовский научно-исследовательский онкологический институт Способ предоперационного лечени рака шейки матки
JPS6056924A (ja) * 1983-09-09 1985-04-02 Ryoichi Ichihara 霊芝茶の製造方法
JPS60190719A (ja) 1984-03-09 1985-09-28 Mitsui Norin Kk 抗腫瘍剤
JPS6450877A (en) * 1987-08-20 1989-02-27 Ichimaru Pharcos Inc Oxygen radical catching and removing agent
FR2633182B1 (fr) * 1988-06-23 1993-07-23 Beljanski Mirko Composition pharmaceutique anticancereuse et methode d'utilisation de l'invention
ES2099099T3 (es) * 1989-11-03 1997-05-16 Alexander S Sun Tratamiento herbaceo de enfermedades malignas.
JP2648720B2 (ja) 1992-03-16 1997-09-03 有限会社日恵 サルノコシカケ科に属する担子菌類のエキスを含有する家畜 用機能食品
JPH05328947A (ja) * 1992-03-31 1993-12-14 Sankaino Chinmi:Kk 茶類錠剤
CN1079361A (zh) * 1993-04-24 1993-12-15 河南中医学院 速溶绿茶及其加工工艺
AU676947B2 (en) * 1993-12-11 1997-03-27 Societe Des Produits Nestle S.A. Ice nucleating agent
CN1104535A (zh) * 1994-05-25 1995-07-05 肖文生 中草药防癌保健茶及其制作方法
CN1049827C (zh) * 1994-06-06 2000-03-01 郭文峰 抗癌冲剂
GB9415492D0 (en) * 1994-08-01 1994-09-21 Celltech Ltd Biological products
DE4431393C1 (de) 1994-08-25 1996-02-15 Heilscher Karl Prof Dr Sc Verfahren zur Kaltgewinnung von Sanddornbeerenölen und Sanddornbeerenmazerat mit reduziertem Fettgehalt und ihre Verwendung
CN1118263A (zh) * 1994-09-06 1996-03-13 毕盛 抗癌中成药-生命之星
CN1105588A (zh) 1994-11-02 1995-07-26 范冬锁 抗癌中药必赐康胶囊及其制造方法
RU2106859C1 (ru) 1994-12-02 1998-03-20 Сенявина Наталья Константиновна Средство для ухода за кожей
IT1275905B1 (it) 1995-03-14 1997-10-24 Indena Spa Frazioni polifenoliche di te', loro uso e formulazioni che le contengono
UA32435C2 (uk) 1995-06-29 2000-12-15 Олексій Генадійович Чистяков Крем для шкіри обличчя "talita"
CN1069036C (zh) * 1995-07-21 2001-08-01 崔景岳 灵芝仙饮
JPH09208484A (ja) * 1996-01-31 1997-08-12 Pola Chem Ind Inc 活性酸素消去剤及びそれを含む組成物
RU2120272C1 (ru) 1996-02-16 1998-10-20 Товарищество с ограниченной ответственностью "Биокосметическая фабрика" Зимний косметический крем для защиты кожи
US5665393A (en) * 1996-09-03 1997-09-09 International Medical Research, Inc. Herbal composition for treating prostate carcinoma
US5910308A (en) * 1997-03-19 1999-06-08 Sante International Inc. Herbal extract composition containing gynostemma pentaphyllum, crataegus pinnatifida and camellia sinensis
RU2129423C1 (ru) 1997-06-19 1999-04-27 Фролов Владимир Владимирович Мазь фролова в.в. для лечения ожогов и инфицированных ран
PL191191B1 (pl) 1997-07-30 2006-03-31 Indena Spa Wyciąg z soi, sposób wytwarzania wyciągu z soi, kompozycja farmaceutyczna oraz zastosowanie wyciągu z soi
RU2134570C1 (ru) 1997-10-06 1999-08-20 Бенчаров Юрий Владимирович Косметический крем
JPH11246402A (ja) 1997-12-26 1999-09-14 Japan Found Cancer Res テロメレ―ス阻害剤
EP0938897A1 (en) 1997-12-26 1999-09-01 Japanese Foundation For Cancer Research Telomerase inhibitor
RU2129003C1 (ru) 1998-04-10 1999-04-20 Гоино Тадаши Средство, обладающее противоопухолевой активностью
US6168795B1 (en) 1998-06-09 2001-01-02 Sant{acute over (e)} International Inc. Method for anticancer therapy using an herbal extract composition
CN1063959C (zh) 1998-08-10 2001-04-04 邹元生 沙棘油复合胶囊
RU2132183C1 (ru) 1998-10-16 1999-06-27 Утешев Даниил Борисович Мазь для лечения воспалительных и аллергических поражений кожи
RU2158599C2 (ru) 1998-12-10 2000-11-10 Брусенцов Николай Антонович Средство для иммунопотенцирования и нормализации тонуса при химиопрофилактике и терапии онкологических, психических, лучевых, инфекционных и простудных заболеваний
CN1232690A (zh) 1998-12-17 1999-10-27 童忠良 银杏沙棘养生茶
CN1116069C (zh) 1999-04-26 2003-07-30 罗萌 一种老年用保健口服液及其制备方法
CN1122528C (zh) 1999-05-11 2003-10-01 吴桂荣 一种复合红花油制剂及含该制剂的药物
US6299925B1 (en) * 1999-06-29 2001-10-09 Xel Herbaceuticals, Inc. Effervescent green tea extract formulation
CN1099892C (zh) * 1999-07-29 2003-01-29 北京理工大学 灵芝孢子中抗肿瘤成分的分离技术
US20010012851A1 (en) * 1999-07-29 2001-08-09 Kristin M. Lundy Nitric oxide releasing oxindole prodrugs for anagesic, anti-inflammatory and disease-modifying use
US6316002B1 (en) * 1999-10-12 2001-11-13 Xin Liu Germination activated red Ganoderma lucidum spores and method for producing the same
JP2001163792A (ja) 1999-12-08 2001-06-19 Koji Tanaka 滋養強壮健康増進用組成物
KR20010074416A (ko) 2000-01-25 2001-08-04 손남율 항바이러스제 및 항암제
WO2001054688A1 (en) * 2000-01-28 2001-08-02 Merck & Co., Inc. Treatment or prevention of prostate cancer with a cox-2 selective inhibiting drug
RU2170101C1 (ru) 2000-02-17 2001-07-10 Общество с ограниченной ответственностью Научно-производственное предприятие "БИОНОКС" Средство для лечения воспалительных заболеваний
KR20010083663A (ko) 2000-02-17 2001-09-01 손남율 항바이러스제 및 항암제
US6399116B1 (en) * 2000-04-28 2002-06-04 Rulin Xiu Rhodiola and used thereof
CN1093405C (zh) 2000-08-10 2002-10-30 重庆市康尔寿保健食品研究所 一种减肥茶
KR20020017675A (ko) * 2000-08-31 2002-03-07 김복량 발암 억제제
AU2001235965A1 (en) 2000-09-15 2002-03-26 Dabur Research Foundation Antibacterial combination comprising neem plant extract
AU2002230775A1 (en) * 2000-12-13 2002-06-24 Georgetown University Gene therapy for prostate cancer: sensibilization of cells to dn a damaging drugs and radiation
CN1305754A (zh) 2000-12-25 2001-08-01 程显峰 海参营养液及其制法
CN1296079C (zh) * 2001-02-13 2007-01-24 廖庆军 一种广谱抗癌、治癌的口服丸剂及其制备方法
CN1312116A (zh) 2001-03-07 2001-09-12 刘俊山 一种配合放化疗治疗晚期肿瘤的瘤复康口服液及制备方法
US6756063B2 (en) * 2001-03-29 2004-06-29 Zoltan Laboratories, Llc Methods and compositions for the treatment of human and animal cancers
EP1374880B1 (en) * 2001-04-02 2006-03-08 Hongfen Li An antineoplastic drug
US6576269B1 (en) * 2001-09-06 2003-06-10 Alexander Y. Korneyev Treating open skin lesions using extract of sea buckthorn
JP2003183176A (ja) * 2001-10-09 2003-07-03 Wellness Movement:Kk 免疫賦活組成物
JP2004217545A (ja) 2003-01-10 2004-08-05 Univ Nihon 新規フラボノイド配糖体及びその用途
JP2005008539A (ja) 2003-06-17 2005-01-13 Fancl Corp マトリックスメタロプロテイナーゼ阻害剤
CN1480209A (zh) 2003-07-18 2004-03-10 陈 列 复方峰胶制剂的加工方法
PL1663103T3 (pl) 2003-09-08 2012-05-31 Genyous Biomed Int Inc Kompozycje roślinnych ekstraktów do leczenia nowotworu
SG149053A1 (en) 2003-09-22 2009-01-29 Genyous Biomed Internat Inc Hippophae rhamnoides compositions for cancer therapy
US20050196409A1 (en) * 2003-09-24 2005-09-08 James Dao Compositions of botanical extracts for treating malignancy-associated changes

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1110571A (zh) * 1994-04-27 1995-10-25 周纯喜 一种抗癌治癌药物及其生产工艺
KR20020078314A (ko) * 2001-04-09 2002-10-18 조갑환 동/식물의 약재를 이용한 건강식품 제조방법
CN1413657A (zh) * 2002-10-17 2003-04-30 王长奎 一种治疗肝癌中药胶囊、药丸及制备方法
CN1436564A (zh) * 2002-12-17 2003-08-20 李天德 治疗肝癌的药物及制备方法

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