CN1845994A - 遍在蛋白特异性蛋白酶 - Google Patents

遍在蛋白特异性蛋白酶 Download PDF

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Publication number
CN1845994A
CN1845994A CNA2004800256544A CN200480025654A CN1845994A CN 1845994 A CN1845994 A CN 1845994A CN A2004800256544 A CNA2004800256544 A CN A2004800256544A CN 200480025654 A CN200480025654 A CN 200480025654A CN 1845994 A CN1845994 A CN 1845994A
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CN
China
Prior art keywords
seq
polypeptide
ubiquitin
antibody
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800256544A
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English (en)
Chinese (zh)
Inventor
A·布林格尔
R·L·蔡
S·克西达
B·皮埃拉
N·R·尼尔马拉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
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Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN1845994A publication Critical patent/CN1845994A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2004800256544A 2003-08-06 2004-08-05 遍在蛋白特异性蛋白酶 Pending CN1845994A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49308003P 2003-08-06 2003-08-06
US60/493,080 2003-08-06

Publications (1)

Publication Number Publication Date
CN1845994A true CN1845994A (zh) 2006-10-11

Family

ID=34135200

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800256544A Pending CN1845994A (zh) 2003-08-06 2004-08-05 遍在蛋白特异性蛋白酶

Country Status (8)

Country Link
EP (1) EP1651764A2 (pt)
JP (1) JP2007501008A (pt)
CN (1) CN1845994A (pt)
AU (1) AU2004262684A1 (pt)
BR (1) BRPI0413364A (pt)
CA (1) CA2534481A1 (pt)
MX (1) MXPA06001393A (pt)
WO (1) WO2005014804A2 (pt)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102947335A (zh) * 2010-04-15 2013-02-27 基因泰克公司 抗多聚遍在蛋白抗体及使用方法
CN103205400A (zh) * 2013-04-19 2013-07-17 青岛大学医学院附属医院 含有人泛素特异性蛋白酶基因USP39-shRNA的重组慢病毒及其应用
CN113454217A (zh) * 2018-12-07 2021-09-28 奥科坦特公司 用于蛋白质-蛋白质相互作用筛选的系统
CN117106911A (zh) * 2023-08-14 2023-11-24 首都医科大学附属北京天坛医院 检测神经鞘瘤的基因集及其多重pcr-高通量测序检测试剂盒

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2182073B1 (en) * 2008-10-30 2014-04-16 Les Laboratoires Servier Ubiquitin specific proteases responsible for MCL-1 stability and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004501637A (ja) * 2000-06-26 2004-01-22 スージェン・インコーポレーテッド 新規プロテアーゼ
JP2002300880A (ja) * 2001-04-04 2002-10-15 Dai Ichi Seiyaku Co Ltd 新規ユビキチン特異プロテアーゼ

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102947335A (zh) * 2010-04-15 2013-02-27 基因泰克公司 抗多聚遍在蛋白抗体及使用方法
US9556262B2 (en) 2010-04-15 2017-01-31 Genentech, Inc. Anti-polyubiquitin antibodies and methods of use
US10100105B2 (en) 2010-04-15 2018-10-16 Genentech, Inc. Anti-polyubiquitin antibodies and methods of use
CN102947335B (zh) * 2010-04-15 2018-11-06 基因泰克公司 抗多聚遍在蛋白抗体及使用方法
US11066463B2 (en) 2010-04-15 2021-07-20 Genentech, Inc. Anti-polyubiquitin antibodies and methods of use
US12037385B2 (en) 2010-04-15 2024-07-16 Genentech, Inc. Anti-polyubiquitin antibodies and methods of use
CN103205400A (zh) * 2013-04-19 2013-07-17 青岛大学医学院附属医院 含有人泛素特异性蛋白酶基因USP39-shRNA的重组慢病毒及其应用
CN103205400B (zh) * 2013-04-19 2014-09-17 青岛大学医学院附属医院 含有人泛素特异性蛋白酶基因USP39-shRNA的重组慢病毒及其应用
CN113454217A (zh) * 2018-12-07 2021-09-28 奥科坦特公司 用于蛋白质-蛋白质相互作用筛选的系统
CN117106911A (zh) * 2023-08-14 2023-11-24 首都医科大学附属北京天坛医院 检测神经鞘瘤的基因集及其多重pcr-高通量测序检测试剂盒

Also Published As

Publication number Publication date
WO2005014804A2 (en) 2005-02-17
WO2005014804A3 (en) 2005-06-30
JP2007501008A (ja) 2007-01-25
BRPI0413364A (pt) 2006-10-17
AU2004262684A1 (en) 2005-02-17
EP1651764A2 (en) 2006-05-03
MXPA06001393A (es) 2006-08-25
CA2534481A1 (en) 2005-02-17

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