BRPI0413364A - proteases especìficas de ubiquitina - Google Patents

proteases especìficas de ubiquitina

Info

Publication number
BRPI0413364A
BRPI0413364A BRPI0413364-1A BRPI0413364A BRPI0413364A BR PI0413364 A BRPI0413364 A BR PI0413364A BR PI0413364 A BRPI0413364 A BR PI0413364A BR PI0413364 A BRPI0413364 A BR PI0413364A
Authority
BR
Brazil
Prior art keywords
useful
specific proteases
ubiquitin
well
present
Prior art date
Application number
BRPI0413364-1A
Other languages
English (en)
Inventor
Adrian Bruengger
Richard Lie Cai
Sophia Kossida
Beno T Pierrat
Nanguneri R Nirmala
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0413364A publication Critical patent/BRPI0413364A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"PROTEASES ESPECìFICAS DE UBIQUITINA". A presente invenção refere-se a novos membros da família de enzimas desubiquitinação (DUBs), bem como fragmentos, derivados, e homólogos destes, biologicamente, diagnosticamente ou terapeuticamente úteis, que são úteis em propósitos de pesquisas, biológicos, clínicos, terapêuticos, bem como prognósticos e diagnósticos. Além disso, os polinucleotídeos e polipeptídeos fornecidos pela presente invenção são úteis para o tratamento e diagnose de câncer de mama, leucemia ou distúrbios cerebrais.
BRPI0413364-1A 2003-08-06 2004-08-05 proteases especìficas de ubiquitina BRPI0413364A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49308003P 2003-08-06 2003-08-06
PCT/EP2004/008798 WO2005014804A2 (en) 2003-08-06 2004-08-05 Ubiquitin-specific protease

Publications (1)

Publication Number Publication Date
BRPI0413364A true BRPI0413364A (pt) 2006-10-17

Family

ID=34135200

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413364-1A BRPI0413364A (pt) 2003-08-06 2004-08-05 proteases especìficas de ubiquitina

Country Status (8)

Country Link
EP (1) EP1651764A2 (pt)
JP (1) JP2007501008A (pt)
CN (1) CN1845994A (pt)
AU (1) AU2004262684A1 (pt)
BR (1) BRPI0413364A (pt)
CA (1) CA2534481A1 (pt)
MX (1) MXPA06001393A (pt)
WO (1) WO2005014804A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2481450T3 (es) * 2008-10-30 2014-07-30 Les Laboratoires Servier Proteasas específicas de ubiquitina responsables de la estabilidad de mcl 1 y su utilización
CA2793503A1 (en) 2010-04-15 2011-10-20 Genentech, Inc. Anti-polyubiquitin antibodies and methods of use
CN103205400B (zh) * 2013-04-19 2014-09-17 青岛大学医学院附属医院 含有人泛素特异性蛋白酶基因USP39-shRNA的重组慢病毒及其应用
EP3891279A1 (en) * 2018-12-07 2021-10-13 Octant, Inc. Systems for protein-protein interaction screening
CN117106911A (zh) * 2023-08-14 2023-11-24 首都医科大学附属北京天坛医院 检测神经鞘瘤的基因集及其多重pcr-高通量测序检测试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1320614A2 (en) * 2000-06-26 2003-06-25 Sugen, Inc. Novel proteases
JP2002300880A (ja) * 2001-04-04 2002-10-15 Dai Ichi Seiyaku Co Ltd 新規ユビキチン特異プロテアーゼ

Also Published As

Publication number Publication date
CA2534481A1 (en) 2005-02-17
WO2005014804A3 (en) 2005-06-30
WO2005014804A2 (en) 2005-02-17
AU2004262684A1 (en) 2005-02-17
JP2007501008A (ja) 2007-01-25
MXPA06001393A (es) 2006-08-25
EP1651764A2 (en) 2006-05-03
CN1845994A (zh) 2006-10-11

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired