BR0312483A - Anticorpos e seus usos - Google Patents
Anticorpos e seus usosInfo
- Publication number
- BR0312483A BR0312483A BR0312483-5A BR0312483A BR0312483A BR 0312483 A BR0312483 A BR 0312483A BR 0312483 A BR0312483 A BR 0312483A BR 0312483 A BR0312483 A BR 0312483A
- Authority
- BR
- Brazil
- Prior art keywords
- antibodies
- methods
- metastasis
- fragments
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- AIDS & HIV (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
Abstract
"ANTICORPOS E SEUS USOS". A presente invenção provê anticorpos ou fragmentos dos mesmos que se ligam a células de câncer e são importantes em fenómenos fisiológicos tais como rolamento de células e metástase. Provê também métodos terapêuticos, métodos para diagnóstico, prognóstico e determinação do estágio da doença e composições usando os referidos anticorpos ou fragmentos dos mesmos. Os métodos e composições de acordo com a presente invenção podem ser usados no diagnóstico e na terapia de doenças como câncer, inclusive crescimento de tumor e metástase, leucemia, doença autoimune e doença inflamatória.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18903202A | 2002-07-01 | 2002-07-01 | |
PCT/US2003/020602 WO2004003166A2 (en) | 2002-07-01 | 2003-06-30 | Antibodies and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0312483A true BR0312483A (pt) | 2005-08-09 |
Family
ID=29999594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0312483-5A BR0312483A (pt) | 2002-07-01 | 2003-06-30 | Anticorpos e seus usos |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1534332A4 (pt) |
JP (1) | JP2005536199A (pt) |
KR (1) | KR20060011925A (pt) |
CN (1) | CN1678347A (pt) |
AU (1) | AU2003263764A1 (pt) |
BR (1) | BR0312483A (pt) |
CA (1) | CA2491363A1 (pt) |
IL (1) | IL166063A0 (pt) |
MX (1) | MXPA05000272A (pt) |
PL (1) | PL374439A1 (pt) |
RU (1) | RU2005101621A (pt) |
WO (1) | WO2004003166A2 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20031714A1 (it) * | 2003-09-05 | 2005-03-06 | Gentium Spa | Formazioni ad azione antitumorale. |
CA2565872C (en) * | 2004-05-11 | 2016-06-21 | Abgenomics Corporation | T-cell death-inducing epitopes |
US20070298034A9 (en) * | 2005-12-09 | 2007-12-27 | Angela Widom | Sulfotyrosine specific antibodies and uses therefor |
DK2637672T3 (en) | 2010-11-12 | 2018-10-22 | Gentium S R L | DEFIBROTID FOR USE IN PROPHYLAXY AND / OR TREATMENT OF GRAPHIC VERSUS HOST DISEASE (GVHD) |
CA2838952C (en) | 2011-06-13 | 2020-11-24 | Stefan Bassarab | Anti-psgl-1 antibodies and uses thereof |
MX352085B (es) | 2012-06-22 | 2017-11-08 | Gentium S R L | Método a base de euglobulina para determinar la actividad biológica de defibrótido. |
EP3026122A1 (en) | 2014-11-27 | 2016-06-01 | Gentium S.p.A. | Cellular-based method for determining the potency of defibrotide |
KR101896751B1 (ko) * | 2015-12-01 | 2018-10-04 | 주식회사 엘지화학 | 열가소성 수지, 이의 제조방법 및 이를 포함하는 열가소성 수지 조성물 |
MA53160A (fr) * | 2018-07-20 | 2021-05-26 | Pf Medicament | Récepteur pour vista |
CN111715409B (zh) * | 2020-07-01 | 2021-07-23 | 中南大学 | 一种微细粒方铅矿的组合铅抑制剂及其应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1131084A4 (en) * | 1998-10-30 | 2001-12-19 | Genetics Inst | INHIBITION OF DIFFERENTIATION OF CYTOTOXIC T CELLS BY P-SELECTINE LIGAND ANTAGONISTS (PSGL) |
BR0109524A (pt) * | 2000-03-24 | 2004-01-20 | Genetics Inst | Molécula de ácido nucleico isolada, vetor, célula hospedeira, método para produzir um polipeptìdeo, polipeptìdeo isolado, anticorpo, método para detectar a presença de um polipeptìdeo em uma amostra, kit, e, métodos para detectar a presença de uma molécula de ácido nucleico em uma amostra, para identificar um composto e para modular a atividade de um polipeptìdeo |
-
2003
- 2003-06-30 EP EP03762258A patent/EP1534332A4/en not_active Withdrawn
- 2003-06-30 JP JP2004518132A patent/JP2005536199A/ja active Pending
- 2003-06-30 CN CNA038204029A patent/CN1678347A/zh active Pending
- 2003-06-30 AU AU2003263764A patent/AU2003263764A1/en not_active Abandoned
- 2003-06-30 PL PL03374439A patent/PL374439A1/xx not_active Application Discontinuation
- 2003-06-30 BR BR0312483-5A patent/BR0312483A/pt not_active IP Right Cessation
- 2003-06-30 MX MXPA05000272A patent/MXPA05000272A/es unknown
- 2003-06-30 KR KR1020047021603A patent/KR20060011925A/ko not_active Application Discontinuation
- 2003-06-30 CA CA002491363A patent/CA2491363A1/en not_active Abandoned
- 2003-06-30 WO PCT/US2003/020602 patent/WO2004003166A2/en not_active Application Discontinuation
- 2003-06-30 RU RU2005101621/13A patent/RU2005101621A/ru not_active Application Discontinuation
-
2004
- 2004-12-30 IL IL16606304A patent/IL166063A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PL374439A1 (en) | 2005-10-17 |
WO2004003166A2 (en) | 2004-01-08 |
JP2005536199A (ja) | 2005-12-02 |
WO2004003166A3 (en) | 2005-03-10 |
EP1534332A4 (en) | 2006-11-22 |
EP1534332A2 (en) | 2005-06-01 |
CN1678347A (zh) | 2005-10-05 |
AU2003263764A1 (en) | 2004-01-19 |
RU2005101621A (ru) | 2005-11-20 |
MXPA05000272A (es) | 2005-09-20 |
KR20060011925A (ko) | 2006-02-06 |
CA2491363A1 (en) | 2004-01-08 |
IL166063A0 (en) | 2006-01-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Vieyra-Garcia et al. | Benign T cells drive clinical skin inflammation in cutaneous T cell lymphoma | |
ATE353974T1 (de) | Verfahren, zusammensetzungen und kits zur identifizierung und überwachung von brustkrebs | |
DE60226499D1 (de) | Verwendung von antikörpern gegen das muc18-antigen | |
WO2006085984A3 (en) | Immune cell biosensors and methods of using same | |
BR0110091A (pt) | Composições e processos para terapia e diagnóstico de câncer de mama | |
WO2006076025A3 (en) | Immune cell biosensors and methods of using same | |
ATE516047T1 (de) | Ovr110-antikörperzusammensetzungen und anwendungsverfahren | |
BRPI0519775A2 (pt) | proteÍna isolada de ligaÇço a antÍgeno, polinucleotÍdeo isolado, plasmÍdio e cÉlula isolada e composiÇço farmacÊutica | |
IL176007A0 (en) | Antibodies specific to c35 and pharmaceutical compositions containing the same | |
DE60028830D1 (de) | Anti-april antikörper und hybridomazellen | |
CY1113096T1 (el) | Αντισωματα της ip-10 και οι χρησεις αυτων | |
DE69633121D1 (de) | Tie-2 liganden, herstellungsverfahren und verwendung | |
WO2004053079A3 (en) | Compositions, splice variants and methods relating to ovarian specific genes and proteins | |
IL145535A0 (en) | Monoclonal antibodies, antigens and diagnosis and therapy of malignant diseases | |
DK0552296T3 (da) | Monoklonale antistoffer fra mus | |
WO2005044990A3 (en) | Use of differentially expressed nucleic acid sequences as biomarkers for cancer | |
BR0312483A (pt) | Anticorpos e seus usos | |
BR0116764A (pt) | moléculas isoladas compreendendo epitopos contendo porções sulfatadas, anticorpos para os referidos epitopos e seus usos | |
DE69841322D1 (de) | Hepatitis c rezeptorprotein cd81 | |
ATE514718T1 (de) | Peptabody für krebsbehandlung | |
BRPI0411945A (pt) | Anticorpos e seus usos | |
DK1051491T3 (da) | Equin Fc Epsilon receptor-alfa-kæde-nukleinsyremolekyler, korresponderende proteiner og anvendelse heraf | |
PL400309A1 (pl) | Kwasy nukleinowe, proteiny oraz przeciwciala BTL-II | |
WO2002014369A3 (en) | Human kininogen d5 domain polypeptides and their use | |
WO2006042005A3 (en) | Global gene expression profiling of circulating tumor cells |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 5A,, 6A. E 7A. ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2064 DE 27/07/2010. |
|
B15K | Others concerning applications: alteration of classification |
Ipc: C07K 16/28 (2006.01), A61K 39/00 (2006.01) |