CN1836569A - Human body nutritious regulator and method for making same and uses - Google Patents
Human body nutritious regulator and method for making same and uses Download PDFInfo
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- CN1836569A CN1836569A CNA2005100246021A CN200510024602A CN1836569A CN 1836569 A CN1836569 A CN 1836569A CN A2005100246021 A CNA2005100246021 A CN A2005100246021A CN 200510024602 A CN200510024602 A CN 200510024602A CN 1836569 A CN1836569 A CN 1836569A
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Abstract
The human body nutrition regulator containing mixed peptide consists of beef enzymolyzing matter, glutamine and aweto or glossy ganoderma as the main components. Its preparation process is also disclosed. It is applied in the following fields: 1. speeding the healing of wound, surgical cut, burns and scalds, radiation injury, ulcer, bedsore, etc; 2. raising the life quality of hepatitis patient via appetizing and promoting rehabilitation; 3. promoting the healing of ulcer in digestive tract; and 4. strengthening the immunity of health people.
Description
Technical field
The present invention relates to beef zymolyte, amino acid additive (glutamine, lysine, arginine, asparatate, or its compound) and traditional precious nourishing agent (Cordyceps sinensis, glossy ganoderma, or its compound) be the human body nutritious regulator that contains hybrid peptide of characteristic component, and its production and application.
Technical background
The present invention selects for use the beef zymolyte as matrix, is aided with valuable ingredients of traditional Chinese medicine such as amino acid additive such as glutamine and Cordyceps sinensis, to strengthen it to accelerated wound healing, the effect that improves immunologic function.
For a long time, beef is subjected to nutritionist's extensive concern always as the important animal food source of the mankind.Enjoy great prestige in the world for a century as a kind of senior nutrition as famous Britain " Bao Weier somatose ", effectively utilized beef extract that substantial connection is arranged with it.It is top grade that my motherland's medical treasure-house is more regarded as beef the tonic of integration of drinking and medicinal herbs, but think the beef tonifying spleen and stomach, and reason is weak.Compendium of Material Medica record: " beef is sweet, warm, nontoxic, and An Zhongyi gas is supported taste, help waist pin ".Beef zymolyte of the present invention contains more rich hybrid peptide, current research result and domestic and international medical practice show, hybrid peptide has good immunological enhancement, especially for trauma patient, greatly strengthen its body self-regeneration function with the continuous formed Toplink of mixing at random of peptide bond by several amino acids.
Cordyceps sinensis is China's tradition rare medicinal herbs, and it distinguishes the flavor of sweet warm in nature, goes into lung kidney two warps, and the lung-yin nourishing kidney-replenishing is the medicine of flat tonifying yin sun.Put down in writing in supplementary Amplifications of the Compendium of Materia Medica (1756) one books of Zhao Xuemin: " Cordyceps sinensis, merit and genseng can be controlled weakness together ".
Glutamine plays an important role in human body as important conditionity essential amino acid, and particularly human body is under stressed conditions such as various wounds (accidental wound, operation injure radiational injury), infection, and the glutamine requirement increases greatly.The function of some important cells all must rely on sufficient glutamine as synthetic, the phagocytosis of cell of protein and the energy supply of lymphocytic propagation and intestinal mucosa cells etc.
Beneficial effect
The present invention has dwindled the gap of China at this technical field and imported product, filled up domestic blank, the development of product of the present invention will be useful trial for the raising of China's biotechnology, and can provide novel effectively product and method for clinical trauma care, postoperative rehabilitation.
Summary of the invention
An object of the present invention is to provide with beef zymolyte, amino acid additive (glutamine, lysine, arginine, asparatate, or its compound) and traditional precious nourishing agent (Cordyceps sinensis, glossy ganoderma, or its compound) be the human body nutritious regulator that contains hybrid peptide of characteristic component.
A further object of the present invention provides the preparation method of described human body nutritious regulator.
Another object of the present invention provides the application of described human body nutritious regulator in following field:
1. acceleration of wound, surgical wound and burn the healing of various surface wounds such as wound, radiational injury, ulcer, bedsore.
2. improve the hepatitis patient quality of life, improve a poor appetite, promote rehabilitation.
3. promote the digestive tract ulcer healing.
4. strengthen the healthy population immunologic function.
The objective of the invention is to implement: a kind of human body nutritious regulator by following method, its characteristic component is the beef zymolyte of 40-90% (V/V), the glutamine of 1-5% (W/V) (or lysine, arginine, asparatate), the Cordyceps sinensis (or glossy ganoderma) of 1-5% (W/V) and the excipient of surplus.After the resin column desalting processing, obtain described human body nutritious regulator.
Described human body nutritious regulator is liquid or dry powder form.
Below in conjunction with specific embodiment the present invention is done further elaboration.
Embodiment 1
Preparation contains the described human body nutritious regulator of 40% beef zymolyte, 1% lysine, 1% Cordyceps extract.
Take by weighing 10g fresh calf meat and clean, go muscle, soak the back pulverizing, add in the 89.8mL sterile distilled water even matter, being heated to 40 ℃, is 7.8 with 2MNaOH solution adjust pH, adds commercially available pancreatin dry powder 0.1g, keeping the pH value is that 7.8,40 ℃ of even matter of insulation were boiled after 1 hour; The time insulation to 40 ℃ to be cooled, adjust pH is 7.8, adds commercially available papain dry powder 0.1g, keeping the pH value is that 7.8,40 ℃ of even matter of insulation were boiled after 1.5 hours, is cooled to room temperature, filtering, is 6.8 with the 10%HCL adjust pH, obtains the beef zymolyte after the resin column desalting processing.
Measure above-mentioned beef zymolyte 40mL, add the commercially available lysine of 1g, the commercially available wild cordyceps extract of 1g, be settled to 100mL, make described human body nutritious regulator after the even matter and be golden yellow liquid with sterile distilled water.
Embodiment 2
Preparation contains the described human body nutritious regulator of 50% beef zymolyte, 1.5% arginine, 1.5% Ganodenna Lucidum P.E.
Take by weighing 20g fresh calf meat and clean, go muscle, soak the back pulverizing, add in the 78mL sterile distilled water even matter, being heated to 40 ℃, is 7.8 with 2M NaOH solution adjust pH, adds commercially available pancreatin dry powder 1.0g, keeping the pH value is that 7.8,40 ℃ of even matter of insulation were boiled after 1 hour; The time insulation to 40 ℃ to be cooled, adjust pH is 7.8, adds commercially available papain dry powder 1.0g, keeping the pH value is that 7.8,40 ℃ of even matter of insulation were boiled after 1.5 hours, is cooled to room temperature, filtering, is 6.8 with the 10%HCL adjust pH, obtains the beef zymolyte after the resin column desalting processing.
Measure above-mentioned beef zymolyte 50mL, add the commercially available arginine of 1.5g, the commercially available Wild ganoderma extract of 1.5g, be settled to 100mL, make described human body nutritious regulator after the even matter and be golden yellow liquid with sterile distilled water.
Embodiment 3
Preparation contains the described human body nutritious regulator of 60% beef zymolyte, 2% asparatate, 2% Cordyceps extract.
Take by weighing the 30g fresh beef and clean, go muscle, soak the back pulverizing, add in the 65mL sterile distilled water even matter, being heated to 50 ℃, is 8.0 with 2M NaOH solution adjust pH, adds commercially available pancreatin dry powder 2.5g, keeping the pH value is that 8.0,50 ℃ of even matter of insulation were boiled after 1 hour; The time insulation to 50 ℃ to be cooled, adjust pH is 8.0, adds commercially available papain dry powder 2.5g, keeping the pH value is that 8.0,50 ℃ of even matter of insulation were boiled after 1.5 hours, is cooled to room temperature, filtering, is 7.0 with the 10%HCL adjust pH, obtains the beef zymolyte after the resin column desalting processing.
Measure above-mentioned beef zymolyte 60mL, add the commercially available asparatate of 2g, the commercially available cultivation northern Chinese caterpillar Fungus of 2g extract, be settled to 100mL with sterile distilled water, even matter is made described human body nutritious regulator after spray-dried and is pale brown look dry powder shape.
Embodiment 4
Preparation contains the described human body nutritious regulator of 70% beef zymolyte, 3% glutamine, 3% Ganodenna Lucidum P.E.
Take by weighing the 40g fresh beef and clean, go muscle, immersion back to pulverize, add in the 54mL sterile distilled water, even matter is heated to 50 ℃, is 8.0 with 2M NaOH solution adjust pH, adds commercially available pancreatin dry powder 3g, and maintenance pH value is that 8.0,50 ℃ of even matter of insulation were boiled after 1 hour; The time insulation to 50 ℃ to be cooled, adjust pH is 8.0, adds commercially available papain dry powder 3g, keeping the pH value is that 8.0,50 ℃ of even matter of insulation were boiled after 1.5 hours, is cooled to room temperature, filtering, is 7.0 with the 10%HCL adjust pH, obtains the beef zymolyte after the resin column desalting processing.
Measure above-mentioned beef zymolyte 70mL, add the commercially available glutamine of 3g, the commercially available cultivation Ganodenna Lucidum P.E of 3g, be settled to 100mL with sterile distilled water, even matter is made described human body nutritious regulator after spray-dried and is pale brown look dry powder shape.
Embodiment 5
Preparation contains the described human body nutritious regulator of 80% beef zymolyte, 4% arginine, 4% Cordyceps extract.
Take by weighing 50g fresh calf meat and clean, go muscle, immersion back to pulverize, add the 42mL sterile distilled water, even matter is heated to 60 ℃, is 8.2 with 2M NaOH solution adjust pH, adds commercially available pancreatin dry powder 4g, and maintenance pH value is that 8.2,60 ℃ of even matter of insulation were boiled after 1 hour; The time insulation to 60 ℃ to be cooled, adjust pH is 8.2, adds commercially available papain dry powder 4g, keeping the pH value is that 8.2,60 ℃ of even matter of insulation were boiled after 1.5 hours, is cooled to room temperature, filtering, is 7.2 with the 10%HCL adjust pH, obtains the beef zymolyte after the resin column desalting processing.
Measure above-mentioned beef zymolyte 80mL, add the commercially available arginine of 4g, the commercially available wild cordyceps extract of 4g, be settled to 100mL, make described human body nutritious regulator after the even matter and be golden yellow liquid with sterile distilled water.
Embodiment 6
Preparation contains the described human body nutritious regulator of 90% beef zymolyte, 5% glutamine, 5% Cordyceps extract.
Take by weighing the 35g fresh beef and clean, go muscle, immersion back to pulverize, add in the 65mL sterile distilled water, even matter is heated to 50 ℃, is 8.0 with 2M NaOH solution adjust pH, adds commercially available pancreatin dry powder 1g, and maintenance pH value is that 8.0,50 ℃ of even matter of insulation were boiled after 1 hour; The time insulation to 50 ℃ to be cooled, adjust pH is 8.0, adds commercially available papain dry powder 0.5g, keeping the pH value is that 8.0,50 ℃ of even matter of insulation were boiled after 1.5 hours, is cooled to room temperature, filtering, is 7.0 with the 10%HCL adjust pH, obtains the beef zymolyte after the resin column desalting processing.
Measure above-mentioned beef zymolyte 90mL, add the commercially available glutamine of 5g, the commercially available cultivation northern Chinese caterpillar Fungus of 5g extract, even matter is made described human body nutritious regulator after spray-dried and is pale brown look dry powder shape.
Claims (5)
1. human body nutritious regulator, its characteristic component is the beef zymolyte of 40-90% (V/V), amino acid additive (glutamine, lysine, arginine, the asparatate of 1-5% (W/V), or its compound), the excipient of the traditional precious nourishing agent of 1-5% (W/V) (Cordyceps sinensis, glossy ganoderma, or its compound) and surplus.
2. human body nutritious regulator according to claim 1 prepares like this:
2.1 pulverize the pancreatin of back adding 0.1-5.0% (W/V), the papain of 0.1-5.0% (W/V) with the fresh beef of 10-50% (W/V), be settled to full dose with sterile distilled water, after abundant hydrolysis, filtering under pH value 7.8-8.2, the 40-60 ℃ condition, obtain the beef zymolyte;
2.2 add the glutamine (or lysine, arginine, asparatate) of 1-5% (W/V), Cordyceps sinensis (or glossy ganoderma) extract of 1-5% (W/V) and the excipient of surplus with the above-mentioned beef zymolyte of 40-90% (V/V), adjust pH is 6.8-7.2 after the even matter, obtains the described human body nutritious regulator of claim 1 after the resin column desalting processing.
3. according to claim 1,2 described human body nutritious regulators, contain hybrid peptide.
4. according to the described human body nutritious regulator of claim 1-3, be liquid or dry powder form.
5. as the preparation of the described human body nutritious regulator of the arbitrary claim of claim 1-4 and in the application in following field:
5.1 acceleration of wound, surgical wound and burn the healing of various surface wounds such as wound, radiational injury, ulcer, bedsore.
5.2 improve the hepatitis patient quality of life, improve a poor appetite, promote rehabilitation.
5.3 promote the digestive tract ulcer healing.
5.4 strengthen the healthy population immunologic function.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2005100246021A CN1836569A (en) | 2005-03-24 | 2005-03-24 | Human body nutritious regulator and method for making same and uses |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2005100246021A CN1836569A (en) | 2005-03-24 | 2005-03-24 | Human body nutritious regulator and method for making same and uses |
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| Publication Number | Publication Date |
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| CN1836569A true CN1836569A (en) | 2006-09-27 |
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| CNA2005100246021A Pending CN1836569A (en) | 2005-03-24 | 2005-03-24 | Human body nutritious regulator and method for making same and uses |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102309006A (en) * | 2011-09-01 | 2012-01-11 | 郭景龙 | Food with health care effect |
| CN103393092A (en) * | 2013-06-26 | 2013-11-20 | 刘宇敏 | Amino acid cordycepin liquid and production method thereof |
| CN105901703A (en) * | 2016-04-19 | 2016-08-31 | 上海海洋大学 | A marine organism type enteral nutrition preparation used for burn patients |
-
2005
- 2005-03-24 CN CNA2005100246021A patent/CN1836569A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102309006A (en) * | 2011-09-01 | 2012-01-11 | 郭景龙 | Food with health care effect |
| CN103393092A (en) * | 2013-06-26 | 2013-11-20 | 刘宇敏 | Amino acid cordycepin liquid and production method thereof |
| CN103393092B (en) * | 2013-06-26 | 2015-08-12 | 刘宇敏 | A kind of amino acid cordycepin liquid and production method thereof |
| CN105901703A (en) * | 2016-04-19 | 2016-08-31 | 上海海洋大学 | A marine organism type enteral nutrition preparation used for burn patients |
| CN105901703B (en) * | 2016-04-19 | 2020-03-10 | 上海海洋大学 | Marine organism type enteral nutrition preparation for burn patients |
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Addressee: Zhao Yingde Document name: Written notice of preliminary examination of application for patent for invention |
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Open date: 20060927 |