CN1795840A - Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function - Google Patents
Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function Download PDFInfo
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- CN1795840A CN1795840A CN 200410099002 CN200410099002A CN1795840A CN 1795840 A CN1795840 A CN 1795840A CN 200410099002 CN200410099002 CN 200410099002 CN 200410099002 A CN200410099002 A CN 200410099002A CN 1795840 A CN1795840 A CN 1795840A
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- oral cavity
- care product
- oral care
- helicobacter pylori
- magnolol
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Abstract
An oral nursing product in the form of gargle liquid, gel, tooth-paste, liniment and spray for resisting against the pylorospirobacillus in oral cavity and preventing decayed tooth is prepared from magnolol, peonol, theapolyphenol, glycyrrhizin, trace elements and enzyme preparation.
Description
Technical field
The present invention relates to the care product of a kind of anti-oral helicobacter pylori and preventing caries function.
Nineteen eighty-three Australia scholar Warren and Marshall first in gastritis patient gastric mucosa biopsy separation detection to helicobacter pylori (hereinafter to be referred as HP), Australian scholar Krajden at first detected HP in the dental plaque of gastritis patient's mouth tooth in 1989, and confirmed that from molecular level it is identical with gastric HP.WHO in 1994 infects HP and classifies the infectious disease of newly looking as, and domestic and foreign literature report HP is the infectious disease that a kind of per os is propagated.Oral cavity HP is the important letter person warehousing that stomach HP infects.Through the Epidemiological study China HP of teenager below 12 years old infection rate up to 40%, adult HP infection rate reaches more than 60%, dental caries is classified as and tumor, the cardiovascular disease arranged side by side three big the most serious diseases of harm humans by WHO, and China's caries incidence of teenager below 12 years old is up to 80%.
HP and cariogenic bacteria belong to microaerobe together; the two bacterium collection that complements each other sticks on the dental plaque; the two has the universality and the disguise of infection; the family and the aggregation of morbidity; in the whole world and China high infection rate is arranged all; in view of this, invent a kind of oral care product and control HP and cariogenic bacteria in the oral cavity, reach the preventing decayed tooth that cleans the teeth and protect the stomach effect with multi-efficiency.
The present invention from magnolol, paeonol, tea polyphenols, glycyrrhizin, etc. extract effective Fungicidal substance the Chinese medicine, can effectively kill HP and cause the dental caries antibacterial, add lanthanum bismuth trace element and lysozyme formulation, help suppressing and removing dental plaque, reach treating both the principal and secondary aspects of a disease, improve and prevent and treat curative effect.
A kind of oral care product provided by the invention for this reason, it can be collutory, gel, toothpaste, liniment and spray.It adopts and comprises that following proportion raw material is prepared from.
Form weight
Form weight %
1, magnolol 0.1～1%
2, paeonol 0.05～0.5%
3, glycyrrhizin 0.01～0.5%
4, tea polyphenols 0.05～1%
5, the Phytic acid lanthanum bismuth 0.001～0.01%
6, enzyme preparation 0.001～0.05%
7, sorbitol 0～12%
8, glycerol 1～8%
9, polyvidon 1～3%
10, sodium lauryl sulphate 0～3%
11, hydroxy methocel 0～2%
12, dalcium biphosphate 0～3%
13, water adds to 100%
Chinese medicines such as magnolol, paeonol, tea polyphenols and glycyrrhizin are antibacterial in the prescription, reach inhibition and kill the HP cariogenic bacteria; Lanthanum bismuth trace element and enzyme preparation are that dental plaque suppresses and cleaning agent, thereby reduce antibacterial and stick and assemble, and reach treating both the principal and secondary aspects of a disease.
Clinical trial shows, the exercise book for students product in 555 routine 10-12 years after continuous one month brushing teeth, 1 year tracing observation, the turning out cloudy property of oral cavity HP reaches more than 90%.
The present invention is a kind of daily dental care product, and is practical and convenient, and a product multiple-effect can effectively be controlled the control of oral cavity HP and dental caries.
The present invention controls the advantage of the oral care implement of oral cavity HP and dental caries:
1, the Chinese medicine that meets composition because of magnolol etc. has significant killing action as becoming chain to bacterium to HP and cariogenic bacteria, and its minimal inhibitory concentration is 0.158mg/L
2,, thereby reduce bacterial adhesion and accumulative chance because of trace element and effective inhibition of enzyme preparation composition and removing dental plaque.
3, this product can be formed collutory, gel, toothpaste, be put the practical application that multiple dosage forms such as smearing agent, spray is fit to different crowd on the skin.
In sum, the present invention is directed to China's teenager HP infection once in 12 years old and dental caries characteristics occurred frequently, method of two kinds of diseases application is prevented and treated obtain the effect of getting twice the result with half the effort.
The specific embodiment:
Embodiment 1 anti-oral cavity HP and anticariogenic collutory
Magnolol 1% paeonol 0.1% glycyrrhizin 0.01%
Tea polyphenols 1% Phytic acid lanthanum bismuth 0.01% enzyme preparation 0.05% glycerol 3%
Polyvidon 1%
Water adds to 100% embodiment 2 anti-oral cavity HP and the anticariogenic gels that get product of bottling after fully second homogenate is carried out with homogenizer in the dissolving back
Magnolol 0.1% paeonol 0.5% glycyrrhizin 0.3%
Tea polyphenols 0.05% Phytic acid lanthanum bismuth 0.001% enzyme preparation 0.001%
Sorbitol 12% glycerol 1% polyvidon 1% hydroxy methocel 1%
Water adds to 100% fill after carrying out second homogenate with homogenizer after the abundant dissolving
Embodiment 3 anti-oral cavity HP and anticariogenic toothpaste
Magnolol 0.5% paeonol 0.5% glycyrrhizin 0.5%
Tea polyphenols 0.5% Phytic acid lanthanum bismuth 0.005% enzyme preparation 0.005%
Glycerol 8% sodium lauryl sulphate 3% hydroxy methocel 2%
Sorbitol 5% dalcium biphosphate 3%
Water adds to 100% after fully stirring, and carries out fill behind the evacuation after the second homogenate with homogenizer.
Embodiment 4 anti-oral cavity HP and anticariogenic erasing agent
Magnolol 0.1% paeonol 0.5% glycyrrhizin 0.3%
Tea polyphenols 1% Phytic acid lanthanum bismuth 0.001% enzyme preparation 0.005% glycerol 1%
Polyvidon 3% hydroxy methocel 1%
Water adds to 100% after fully stirring, and carries out fill after the second homogenate with homogenizer.
Embodiment 5 anti-oral cavity HP and anticariogenic sprays
Magnolol 0.1% paeonol 0.5% glycyrrhizin 0.3%
Tea polyphenols 1% Phytic acid lanthanum bismuth 0.001% enzyme preparation 0.005% glycerol 2%
Sorbitol 5% polyvidon 1%
Water adds to 100% after fully stirring, and carries out fill after the second homogenate with homogenizer.
Claims (5)
1, the oral care product of a kind of anti helicobacter pylori of oral cavity and preventing caries function.Make comprising following proportioning raw material.
Form weight %
1, magnolol 0.1～1%
2, paeonol 0.05～0.5%
3, glycyrrhizin 0.01～0.5%
4, tea polyphenols 0.05～1%
5, Phytic acid lanthanum 0.001～0.01%
6, enzyme preparation 0.001～0.05%
7, sorbitol 0～12%
8, glycerol 1～8%
9, polyvidon 1～3%
10, sodium lauryl sulphate 0～3%
11, hydroxy methocel 0～2%
12, dalcium biphosphate 0～3%
13, water adds to 100%
2, oral care product as claimed in claim 1 is characterized in that it is collutory, gel, toothpaste or liniment and spray.
3, oral care product as claimed in claim 1, what it is characterized in that anti helicobacter pylori of oral cavity and anti-caries effect all is Chinese herbal medicine compositions, refers to magnolol, paeonol, tea polyphenols, glycyrrhizin, phytic acid
4, oral care product as claimed in claim 1 is characterized in that institute's enzyme-containing formulation comprises lysozyme, lipase.
5, oral care product as claimed in claim is characterized in that used trace element comprises lanthanum, bismuth.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410099002 CN1795840A (en) | 2004-12-24 | 2004-12-24 | Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410099002 CN1795840A (en) | 2004-12-24 | 2004-12-24 | Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1795840A true CN1795840A (en) | 2006-07-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410099002 Pending CN1795840A (en) | 2004-12-24 | 2004-12-24 | Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function |
Country Status (1)
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| CN (1) | CN1795840A (en) |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2363135A1 (en) * | 2010-03-01 | 2011-09-07 | Antonio Puig, S.A. | Anti-jellyfish compositions |
| CN102204874A (en) * | 2011-01-28 | 2011-10-05 | 义乌市爱尚日用品有限公司 | Anti-halitosis toothpaste containing natural drug compound components |
| CN102218048A (en) * | 2011-04-21 | 2011-10-19 | 上海莱博生物科技有限公司 | Application of magnolol in preparation of external preparations and daily chemical products for treating dermatosis caused by malassezia |
| WO2013091139A1 (en) * | 2011-12-21 | 2013-06-27 | Colgate-Palmolive Company | Heatiness and salivary secretory immunoglobulin |
| CN103479547A (en) * | 2013-09-11 | 2014-01-01 | 上海方木精细化工有限公司 | Lemon gargle |
| CN103479548A (en) * | 2013-09-11 | 2014-01-01 | 上海方木精细化工有限公司 | Momordica grosvenori gargle |
| CN103908423A (en) * | 2014-04-24 | 2014-07-09 | 上海利康消毒高科技有限公司 | Anti-oral helicobacter pylori traditional Chinese medicine toothpaste |
| CN103920143A (en) * | 2014-04-24 | 2014-07-16 | 上海利康消毒高科技有限公司 | Chinese lobelia spray for resisting oral helicobacter pylori |
| AU2011384378B2 (en) * | 2011-12-21 | 2014-09-18 | Colgate-Palmolive Company | Methods and products to diagnose and treat heatiness |
| CN105147650A (en) * | 2015-10-14 | 2015-12-16 | 上海中医药大学 | Medical application of paeonol |
| CN108670931A (en) * | 2018-07-24 | 2018-10-19 | 冯绍良 | A kind of toothpaste and its production method for capableing of suppressing and killing helicobacter pylori |
| CN109010404A (en) * | 2018-09-26 | 2018-12-18 | 广东南方洁灵科技实业有限公司 | A kind of anti-helicobacter pylori oral cavity compound and its preparation method and application |
| CN109172555A (en) * | 2018-10-30 | 2019-01-11 | 武汉卫无忧生物科技有限公司 | Purposes of the Paeonol in the drug for preparing anti-helicobacter pylori |
| CN111358721A (en) * | 2020-04-12 | 2020-07-03 | 广东医创时代科技发展有限公司 | Chinese herbal medicine oral care product for preventing and treating helicobacter pylori infection of oral cavity and various oral diseases |
-
2004
- 2004-12-24 CN CN 200410099002 patent/CN1795840A/en active Pending
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2363135A1 (en) * | 2010-03-01 | 2011-09-07 | Antonio Puig, S.A. | Anti-jellyfish compositions |
| CN102204874A (en) * | 2011-01-28 | 2011-10-05 | 义乌市爱尚日用品有限公司 | Anti-halitosis toothpaste containing natural drug compound components |
| CN102218048A (en) * | 2011-04-21 | 2011-10-19 | 上海莱博生物科技有限公司 | Application of magnolol in preparation of external preparations and daily chemical products for treating dermatosis caused by malassezia |
| CN102218048B (en) * | 2011-04-21 | 2013-02-27 | 上海莱博生物科技有限公司 | Application of magnolol in preparation of external preparations and daily chemical products for treating dermatosis caused by malassezia |
| AU2011384377B2 (en) * | 2011-12-21 | 2014-09-18 | Colgate-Palmolive Company | Heatiness and salivary secretory immunoglobulin |
| WO2013091139A1 (en) * | 2011-12-21 | 2013-06-27 | Colgate-Palmolive Company | Heatiness and salivary secretory immunoglobulin |
| AU2011384378B2 (en) * | 2011-12-21 | 2014-09-18 | Colgate-Palmolive Company | Methods and products to diagnose and treat heatiness |
| CN103479548B (en) * | 2013-09-11 | 2016-05-11 | 上海方木精细化工有限公司 | Momordica grosvenori GARG |
| CN103479548A (en) * | 2013-09-11 | 2014-01-01 | 上海方木精细化工有限公司 | Momordica grosvenori gargle |
| CN103479547A (en) * | 2013-09-11 | 2014-01-01 | 上海方木精细化工有限公司 | Lemon gargle |
| CN103479547B (en) * | 2013-09-11 | 2016-05-11 | 上海方木精细化工有限公司 | Lemon GARG |
| CN103920143A (en) * | 2014-04-24 | 2014-07-16 | 上海利康消毒高科技有限公司 | Chinese lobelia spray for resisting oral helicobacter pylori |
| CN103908423A (en) * | 2014-04-24 | 2014-07-09 | 上海利康消毒高科技有限公司 | Anti-oral helicobacter pylori traditional Chinese medicine toothpaste |
| CN103920143B (en) * | 2014-04-24 | 2017-02-01 | 上海利康消毒高科技有限公司 | Chinese lobelia spray for resisting oral helicobacter pylori |
| CN105147650A (en) * | 2015-10-14 | 2015-12-16 | 上海中医药大学 | Medical application of paeonol |
| CN108670931A (en) * | 2018-07-24 | 2018-10-19 | 冯绍良 | A kind of toothpaste and its production method for capableing of suppressing and killing helicobacter pylori |
| CN109010404A (en) * | 2018-09-26 | 2018-12-18 | 广东南方洁灵科技实业有限公司 | A kind of anti-helicobacter pylori oral cavity compound and its preparation method and application |
| CN109172555A (en) * | 2018-10-30 | 2019-01-11 | 武汉卫无忧生物科技有限公司 | Purposes of the Paeonol in the drug for preparing anti-helicobacter pylori |
| CN111358721A (en) * | 2020-04-12 | 2020-07-03 | 广东医创时代科技发展有限公司 | Chinese herbal medicine oral care product for preventing and treating helicobacter pylori infection of oral cavity and various oral diseases |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
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