CN103479548B - Momordica grosvenori GARG - Google Patents

Momordica grosvenori GARG Download PDF

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Publication number
CN103479548B
CN103479548B CN201310413484.8A CN201310413484A CN103479548B CN 103479548 B CN103479548 B CN 103479548B CN 201310413484 A CN201310413484 A CN 201310413484A CN 103479548 B CN103479548 B CN 103479548B
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Prior art keywords
garg
momordica grosvenori
present
sorbierite
ethanol
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CN201310413484.8A
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CN103479548A (en
Inventor
宋繁华
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Guangxi Yongfu Baihongyuan Technology Co., Ltd.
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SHANGHAI FANGMU FINE CHEMICAL Co Ltd
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  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention relates to a kind of Momordica grosvenori GARG, formed by following compositions in weight percentage: Fructus Momordicae fructoside 0.05-0.15%, sorbierite 12-18%, ethanol 8-12%, glucose 0.1-0.3%, cocounut oil acyl both sexes guanidine-acetic acid sodium 0.2-0.4%, surplus are water. Momordica grosvenori GARG of the present invention oral cavity cleaning, fresh breath.

Description

Momordica grosvenori GARG
Technical field
The present invention relates to a kind of GARG, be specifically related to a kind of Momordica grosvenori GARG.
Background technology
GARG, also referred to as mouthwash, gargle etc. GARG is easy to use, saves time, and notNeeding special apparatus, is very effective oral hygiene appliance.
The bacterium of meeting residual harmful, tartar, calculus dentalis, swill etc. on mucous membrane of mouth and tooth, warpCorrupt, fermentation can produce stench. Therefore the use of GARG is very usual and necessary.
Summary of the invention
A kind of Momordica grosvenori GARG, is made up of following compositions in weight percentage: Fructus Momordicae fructoside0.05-0.15%, sorbierite 12-18%, ethanol 8-12%, glucose 0.1-0.3%, cocounut oil acyl both sexes baseSodium acetate 0.2-0.4%, surplus are water.
Preferably,
A kind of Momordica grosvenori GARG, is made up of following compositions in weight percentage: Fructus Momordicae fructoside0.05-0.15%, sorbierite 12-18%, ethanol 8-12%, glucose 0.1-0.3%, cocounut oil acyl both sexes baseSodium acetate 0.2-0.4%, biological antibiosis agent 0.3-0.7%, surplus are water.
Described biological antibiosis agent is a kind of or its mixture in aurantiin, glycyrrhizin and vanillic aldehyde. ExcellentBiological antibiosis agent described in selection of land, is made up of by weight following component: aurantiin 50-70 part, glycyrrhizinElement 10-30 part and vanillic aldehyde 10-30 part. Wherein, aurantiin, CAS accession number: 10236-47-2.Glycyrrhizin, CAS accession number: 1405-86-3. Vanillic aldehyde, CAS accession number: 121-33-5.
Momordica grosvenori GARG of the present invention, via common process, forms by mixed above-mentioned each raw material manufacture.
Momordica grosvenori is described as " angle fruit " by people. Mainly originate in Lingui district of Guangxi Zhuang Autonomous Region Guilin CityWith the mountain area of Yongfu county, be the famous and precious local and special products in Guilin. Fruits nutrition is worth very high, containing abundant supporting one's familyElement C (in every 100 grams of fresh fruits containing 400 milligrams~500 milligrams) and glucoside, fructose, glucose,Protein, lipid etc. Arhat fruity is sweet cool in nature, returns lung, large intestine channel, moistens the lung and relieve the cough, and promotes the production of body fluid to quench thirstEffect, be applicable to lung heat or xeropulmonary cough, it is thirsty etc. that pertussis and hot summer weather are hindered Tianjin, also has in addition ease constipationEffect of defaecation.
Momordica grosvenori GARG of the present invention oral cavity cleaning, fresh breath.
Detailed description of the invention
Embodiment 1-4
Composition of raw materials list position: kilogram
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Fructus Momordicae fructoside 0.1 0.1 0.1 0.1
Sorbierite 15 15 15 15
Ethanol 10 10 10 10
Glucose 0.2 0.2 0.2 0.2
Cocounut oil acyl both sexes guanidine-acetic acid sodium 0.3 0.3 0.3 0.3
Aurantiin 0.5 / / 0.3
Glycyrrhizin / 0.5 / 0.1
Vanillic aldehyde / / 0.5 0.1
Water To 100 To 100 To 100 To 100
In each embodiment, raw material gross weight is 100 kilograms, and wherein the addition of water subtracts by 100 kilogramsRemove other raw material weights and determine.
Momordica grosvenori GARG of the present invention can adopt the conventional method preparation of this area completely, as " washing agentRecipe handbook " (Xu Baocai etc. write, Chemical Industry Press, chemistry and applied chemistry publishing centre,January in 2006 the 1st edition) the disclosed GARG production technology of 700-717 page is prepared. It is warpBy common process, form by mixed above-mentioned each raw material manufacture. Obviously, GARG in the present inventionPreparation method be prior art, not special character, main improvement of the present invention is just formulaDifferent.
Test case
Get respectively embodiment 1-4 prepared Momordica grosvenori GARG and directly carry out fungistatic effect without dilutionEvaluating and measuring, carries out antibacterial according to QB/T3738 " evaluation method of daily chemical products antibacterial bacteriostatic effect "Test, 1 minute action time, activity is 100% Momordica grosvenori GARG, test strain is: goldStaphylococcus aureus and Escherichia coli.
Fungistatic effect test chart
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Bacteriostasis rate (staphylococcus aureus), % 90.5 89.7 90.4 91.8
Bacteriostasis rate (Escherichia coli), % 90.8 90.2 89.8 91.6
From upper table data, the prepared Momordica grosvenori GARG of embodiment 1-4 has preferably antibacterial pressing downBacterium effect.

Claims (1)

1. a Momordica grosvenori GARG, is characterized in that, by following compositions in weight percentageComposition: Fructus Momordicae fructoside 0.05-0.15%, sorbierite 12-18%, ethanol 8-12%, grapeSugar 0.1-0.3%, cocounut oil acyl both sexes guanidine-acetic acid sodium 0.2-0.4%, biological antibiosis agent 0.3-0.7%,Surplus is water;
Described biological antibiosis agent, is made up of by weight following component: aurantiin 50-70 part,Glycyrrhizin 10-30 part and vanillic aldehyde 10-30 part.
CN201310413484.8A 2013-09-11 2013-09-11 Momordica grosvenori GARG Active CN103479548B (en)

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Application Number Priority Date Filing Date Title
CN201310413484.8A CN103479548B (en) 2013-09-11 2013-09-11 Momordica grosvenori GARG

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CN103479548B true CN103479548B (en) 2016-05-11

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648095A (en) * 2017-09-14 2018-02-02 山东新华医疗器械股份有限公司 Fructus Momordicae fructoside mouthwash and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1795840A (en) * 2004-12-24 2006-07-05 上海利康美瑞药业高科技有限公司 Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function
CN101249056A (en) * 2008-01-11 2008-08-27 美晨集团股份有限公司 Anti-inflammation gargle water and method of preparing the same
CN101442996A (en) * 2006-03-10 2009-05-27 土田裕三 Antimicrobial agent and antimicrobial composition
CN101961341A (en) * 2009-07-21 2011-02-02 湖北汇特生物医药技术有限公司 Application of glucose lowering function of mogrosides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1795840A (en) * 2004-12-24 2006-07-05 上海利康美瑞药业高科技有限公司 Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function
CN101442996A (en) * 2006-03-10 2009-05-27 土田裕三 Antimicrobial agent and antimicrobial composition
CN101249056A (en) * 2008-01-11 2008-08-27 美晨集团股份有限公司 Anti-inflammation gargle water and method of preparing the same
CN101961341A (en) * 2009-07-21 2011-02-02 湖北汇特生物医药技术有限公司 Application of glucose lowering function of mogrosides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
柚皮苷在口腔护理用品中的应用研究;覃青云等;《牙膏工业》;20090630;第19卷(第2期);25-29 *

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Effective date of registration: 20170113

Address after: Magnolia Street Bao Su Qiao Yongfu County, Guilin city 541805 the Guangxi Zhuang Autonomous Region Zhen Ji

Patentee after: Guangxi Yongfu Baihongyuan Technology Co., Ltd.

Address before: 201107 Shanghai city Minhang District Minhang Road 88 Lane No. 1-30 building twenty-second room T159

Patentee before: Shanghai Fangmu Fine Chemical Co., Ltd.