CN103479548A - Momordica grosvenori gargle - Google Patents

Momordica grosvenori gargle Download PDF

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Publication number
CN103479548A
CN103479548A CN201310413484.8A CN201310413484A CN103479548A CN 103479548 A CN103479548 A CN 103479548A CN 201310413484 A CN201310413484 A CN 201310413484A CN 103479548 A CN103479548 A CN 103479548A
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China
Prior art keywords
fructus momordicae
gargarism
momordica grosvenori
gargle
glucose
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Granted
Application number
CN201310413484.8A
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Chinese (zh)
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CN103479548B (en
Inventor
宋繁华
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Guangxi Yongfu Baihongyuan Technology Co., Ltd.
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SHANGHAI FANGMU FINE CHEMICAL Co Ltd
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Priority to CN201310413484.8A priority Critical patent/CN103479548B/en
Publication of CN103479548A publication Critical patent/CN103479548A/en
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Publication of CN103479548B publication Critical patent/CN103479548B/en
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to Momordica grosvenori gargle. The Momordica grosvenori gargle comprises, by weight, 0.05-0.15% of Momordica grosvenori glycoside, 12-18% of sorbitol, 8-12% of ethyl alcohol, 0.1-0.3% of glucose, 0.2-0.4% of sodium cocoamphoacetate, and the balance water. The Momordica grosvenori gargle cleans the oral cavity and freshens the breath.

Description

The Fructus Momordicae gargarism
Technical field
The present invention relates to a kind of gargarism, be specifically related to a kind of Fructus Momordicae gargarism.
Background technology
Gargarism, also referred to as collutory, collutory etc.Gargarism is easy to use, saves time, and does not need special apparatus, is very effective oral hygiene appliance.
On oral mucosa and tooth, the antibacterial of meeting residual harmful, tartar, dental calculus, food debris etc., can produce stench through corrupt, fermentation.Therefore very usual and necessary during the use of gargarism.
Summary of the invention
A kind of Fructus Momordicae gargarism is comprised of following compositions in weight percentage: Fructus Momordicae fructoside 0.05-0.15%, sorbitol 12-18%, ethanol 8-12%, glucose 0.1-0.3%, cocos nucifera oil acyl both sexes guanidine-acetic acid sodium 0.2-0.4%, surplus are water.
Preferably,
A kind of Fructus Momordicae gargarism is comprised of following compositions in weight percentage: Fructus Momordicae fructoside 0.05-0.15%, sorbitol 12-18%, ethanol 8-12%, glucose 0.1-0.3%, cocos nucifera oil acyl both sexes guanidine-acetic acid sodium 0.2-0.4%, biological antibiosis agent 0.3-0.7%, surplus are water.
Described biological antibiosis agent is a kind of or its mixture in naringin, glycyrrhizin and vanillin.Preferably described biological antibiosis agent, consist of by weight following component: naringin 50-70 part, glycyrrhizin 10-30 part and vanillin 10-30 part.Wherein, naringin, CAS accession number: 10236-47-2.Glycyrrhizin, CAS accession number: 1405-86-3.Vanillin, CAS accession number: 121-33-5.
Fructus Momordicae gargarism of the present invention, via common process, forms by mixed above-mentioned each raw material manufacture.
Fructus Momordicae is described as " angle fruit " by people.Mainly originate in the famous and precious local and special products in ,Shi Guilin, mountain area of Lingui district, Guilin City, Guangxi Zhuang Autonomous Region and Yongfu county.Fruits nutrition is worth very high, contains abundant vitamin C (in every 100 gram fresh fruits, containing 400 milligrams~500 milligrams) and glucoside, fructose, glucose, protein, lipid etc.The Fructus Momordicae sweet in the mouth is cool in nature, returns lung, large intestine channel, and nourishing the lung to arrest cough is arranged, and the effect of promoting the production of body fluid to quench thirst is applicable to lung-heat or xeropulmonary cough, and pertussis and summer-heat impairment of body fluid are thirsty etc., also has in addition the effect of loosening bowel to relieve constipation.
Fructus Momordicae gargarism cleaning oral cavity of the present invention, fresh breath.
The specific embodiment
Embodiment 1-4
Composition of raw materials list position: kilogram
? Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Fructus Momordicae fructoside 0.1 0.1 0.1 0.1
Sorbitol 15 15 15 15
Ethanol 10 10 10 10
Glucose 0.2 0.2 0.2 0.2
Cocos nucifera oil acyl both sexes guanidine-acetic acid sodium 0.3 0.3 0.3 0.3
Naringin 0.5 / / 0.3
Glycyrrhizin / 0.5 / 0.1
Vanillin / / 0.5 0.1
Water To 100 To 100 To 100 To 100
In each embodiment, the raw material gross weight is 100 kilograms, and wherein the addition of water deducts other raw material weights by 100 kilograms and determines.
Fructus Momordicae gargarism of the present invention can adopt the conventional method preparation of this area fully, as " detergent compositions workshop manual ", (Xu Baocai etc. write, Chemical Industry Press, chemistry and applied chemistry publishing centre, January in 2006 the 1st edition) the disclosed gargarism production technology of 700-717 page is prepared.Via common process, by mixed above-mentioned each raw material manufacture, form.Obviously, the preparation method of gargarism is prior art in the present invention, does not have special character, and main improvement of the present invention just is the difference of formula.
Test case
Get respectively the prepared Fructus Momordicae gargarism of embodiment 1-4 and directly carry out the evaluating and measuring of fungistatic effect without dilution, carry out bacteriostatic test according to QB/T3738 " evaluation methodology of daily chemical products antibacterial bacteriostatic effect ", 1 minute action time, activity is 100% Fructus Momordicae gargarism, and test strain is: staphylococcus aureus and escherichia coli.
The fungistatic effect test chart
? Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Bacteriostasis rate (staphylococcus aureus), % 90.5 89.7 90.4 91.8
Bacteriostasis rate (escherichia coli), % 90.8 90.2 89.8 91.6
From upper table data, the prepared Fructus Momordicae gargarism of embodiment 1-4 has antibacterial bacteriostatic effect preferably.

Claims (4)

1. a Fructus Momordicae gargarism, is characterized in that, following compositions in weight percentage, consists of: Fructus Momordicae fructoside 0.05-0.15%, sorbitol 12-18%, ethanol 8-12%, glucose 0.1-0.3%, cocos nucifera oil acyl both sexes guanidine-acetic acid sodium 0.2-0.4%, surplus are water.
2. a Fructus Momordicae gargarism, it is characterized in that, be comprised of following compositions in weight percentage: Fructus Momordicae fructoside 0.05-0.15%, sorbitol 12-18%, ethanol 8-12%, glucose 0.1-0.3%, cocos nucifera oil acyl both sexes guanidine-acetic acid sodium 0.2-0.4%, biological antibiosis agent 0.3-0.7%, surplus are water.
3. Fructus Momordicae gargarism as claimed in claim 2, is characterized in that, described biological antibiosis agent is a kind of or its mixture in naringin, glycyrrhizin and vanillin.
4. Fructus Momordicae gargarism as claimed in claim 3, is characterized in that, described biological antibiosis agent consists of by weight following component: naringin 50-70 part, glycyrrhizin 10-30 part and vanillin 10-30 part.
CN201310413484.8A 2013-09-11 2013-09-11 Momordica grosvenori GARG Active CN103479548B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648095A (en) * 2017-09-14 2018-02-02 山东新华医疗器械股份有限公司 Fructus Momordicae fructoside mouthwash and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1795840A (en) * 2004-12-24 2006-07-05 上海利康美瑞药业高科技有限公司 Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function
CN101249056A (en) * 2008-01-11 2008-08-27 美晨集团股份有限公司 Anti-inflammation gargle water and method of preparing the same
CN101442996A (en) * 2006-03-10 2009-05-27 土田裕三 Antimicrobial agent and antimicrobial composition
CN101961341A (en) * 2009-07-21 2011-02-02 湖北汇特生物医药技术有限公司 Application of glucose lowering function of mogrosides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1795840A (en) * 2004-12-24 2006-07-05 上海利康美瑞药业高科技有限公司 Oral cavity care product for anti helicobacter pylori of oral cavity and preventing caries function
CN101442996A (en) * 2006-03-10 2009-05-27 土田裕三 Antimicrobial agent and antimicrobial composition
CN101249056A (en) * 2008-01-11 2008-08-27 美晨集团股份有限公司 Anti-inflammation gargle water and method of preparing the same
CN101961341A (en) * 2009-07-21 2011-02-02 湖北汇特生物医药技术有限公司 Application of glucose lowering function of mogrosides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
覃青云等: "柚皮苷在口腔护理用品中的应用研究", 《牙膏工业》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648095A (en) * 2017-09-14 2018-02-02 山东新华医疗器械股份有限公司 Fructus Momordicae fructoside mouthwash and preparation method thereof

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Effective date of registration: 20170113

Address after: Magnolia Street Bao Su Qiao Yongfu County, Guilin city 541805 the Guangxi Zhuang Autonomous Region Zhen Ji

Patentee after: Guangxi Yongfu Baihongyuan Technology Co., Ltd.

Address before: 201107 Shanghai city Minhang District Minhang Road 88 Lane No. 1-30 building twenty-second room T159

Patentee before: Shanghai Fangmu Fine Chemical Co., Ltd.