CN103479533A - Paeonol gargle - Google Patents
Paeonol gargle Download PDFInfo
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- CN103479533A CN103479533A CN201310413455.1A CN201310413455A CN103479533A CN 103479533 A CN103479533 A CN 103479533A CN 201310413455 A CN201310413455 A CN 201310413455A CN 103479533 A CN103479533 A CN 103479533A
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- Prior art keywords
- paeonol
- gargarism
- gargle
- naringin
- sodium monofluorophosphate
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Abstract
The invention relates to paeonol gargle. The paeonol gargle is composed of, by weight, 0.2-0.4% of paeonol, 0.12-0.28% of naringin dihydrochalcone, 12-16% of glycerinum, 0.1-0.3% of sodium monofluorophosphate, 8-12% of ethyl alcohol, 0.2-0.4% of octyl glucoside and the balance water. The paeonol gargle clears the oral cavity, has special fragrance of the paeonol, and can effectively eliminate ozostomia.
Description
Technical field
The present invention relates to a kind of gargarism, be specifically related to a kind of paeonol gargarism.
Background technology
Gargarism, also referred to as collutory, collutory etc.Gargarism is easy to use, saves time, and does not need special apparatus, is very effective oral hygiene appliance.
On oral mucosa and tooth, the antibacterial of meeting residual harmful, tartar, dental calculus, food debris etc., can produce stench through corrupt, fermentation.Therefore very usual and necessary during the use of gargarism.
Summary of the invention
A kind of paeonol gargarism is comprised of following compositions in weight percentage: paeonol 0.2-0.4%, naringin dihydrochalcone 0.12-0.28%, glycerol 12-16%, sodium monofluorophosphate 0.1-0.3%, ethanol 8-12%, octyl glucoside 0.2-0.4%, surplus are water.
Preferably,
A kind of paeonol gargarism is comprised of following compositions in weight percentage: paeonol 0.2-0.4%, naringin dihydrochalcone 0.12-0.28%, glycerol 12-16%, sodium monofluorophosphate 0.1-0.3%, ethanol 8-12%, octyl glucoside 0.2-0.4%, biological antibiosis agent 0.4-0.6%, surplus are water.
Described biological antibiosis agent is a kind of or its mixture in naringin, glycyrrhizin and vanillin.Preferably described biological antibiosis agent, consist of by weight following component: naringin 50-70 part, glycyrrhizin 10-30 part and vanillin 10-30 part.Wherein, naringin, CAS accession number: 10236-47-2.Glycyrrhizin, CAS accession number: 1405-86-3.Vanillin, CAS accession number: 121-33-5.
Paeonol gargarism of the present invention, via common process, forms by mixed above-mentioned each raw material manufacture.
Paeonol gargarism of the present invention, clean oral cavity, have unique delicate fragrance of paeonol, can effectively eliminate halitosis.
The specific embodiment
Embodiment 1-4
Composition of raw materials list position: kilogram
| ? | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
| Paeonol | 0.3 | 0.3 | 0.3 | 0.3 |
| Naringin dihydrochalcone | 0.2 | 0.2 | 0.2 | 0.2 |
| Glycerol | 14 | 14 | 14 | 14 |
| Sodium monofluorophosphate | 0.2 | 0.2 | 0.2 | 0.2 |
| Ethanol | 10 | 10 | 10 | 10 |
| Octyl glucoside | 0.3 | 0.3 | 0.3 | 0.3 |
| Naringin | 0.5 | / | / | 0.3 |
| Glycyrrhizin | / | 0.5 | / | 0.1 |
| Vanillin | / | / | 0.5 | 0.1 |
| Water | To 100 | To 100 | To 100 | To 100 |
In each embodiment, the raw material gross weight is 100 kilograms, and wherein the addition of water deducts other raw material weights by 100 kilograms and determines.
Paeonol gargarism of the present invention can adopt the conventional method preparation of this area fully, as " detergent compositions workshop manual ", (Xu Baocai etc. write, Chemical Industry Press, chemistry and applied chemistry publishing centre, January in 2006 the 1st edition) the disclosed gargarism production technology of 700-717 page is prepared.Via common process, by mixed above-mentioned each raw material manufacture, form.Obviously, the preparation method of gargarism is prior art in the present invention, does not have special character, and main improvement of the present invention just is the difference of formula.
Test case
Get respectively the prepared paeonol gargarism of embodiment 1-4 and directly carry out the evaluating and measuring of fungistatic effect without dilution, carry out bacteriostatic test according to QB/T3738 " evaluation methodology of daily chemical products antibacterial bacteriostatic effect ", 1 minute action time, activity is 100% paeonol gargarism, and test strain is: staphylococcus aureus and escherichia coli.
The fungistatic effect test chart
| ? | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
| Bacteriostasis rate (staphylococcus aureus), % | 89.2 | 88.7 | 89.0 | 90.5 |
| Bacteriostasis rate (escherichia coli), % | 90.3 | 89.8 | 89.5 | 91.4 |
From upper table data, the prepared paeonol gargarism of embodiment 1-4 has antibacterial bacteriostatic effect preferably.
Claims (4)
1. a paeonol gargarism, it is characterized in that, be comprised of following compositions in weight percentage: paeonol 0.2-0.4%, naringin dihydrochalcone 0.12-0.28%, glycerol 12-16%, sodium monofluorophosphate 0.1-0.3%, ethanol 8-12%, octyl glucoside 0.2-0.4%, surplus are water.
2. a paeonol gargarism, it is characterized in that, be comprised of following compositions in weight percentage: paeonol 0.2-0.4%, naringin dihydrochalcone 0.12-0.28%, glycerol 12-16%, sodium monofluorophosphate 0.1-0.3%, ethanol 8-12%, octyl glucoside 0.2-0.4%, biological antibiosis agent 0.4-0.6%, surplus are water.
3. paeonol gargarism as claimed in claim 2, is characterized in that, described biological antibiosis agent is a kind of or its mixture in naringin, glycyrrhizin and vanillin.
4. paeonol gargarism as claimed in claim 3, is characterized in that, described biological antibiosis agent consists of by weight following component: naringin 50-70 part, glycyrrhizin 10-30 part and vanillin 10-30 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310413455.1A CN103479533B (en) | 2013-09-11 | 2013-09-11 | Paeonol gargle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310413455.1A CN103479533B (en) | 2013-09-11 | 2013-09-11 | Paeonol gargle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103479533A true CN103479533A (en) | 2014-01-01 |
| CN103479533B CN103479533B (en) | 2016-08-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310413455.1A Expired - Fee Related CN103479533B (en) | 2013-09-11 | 2013-09-11 | Paeonol gargle |
Country Status (1)
| Country | Link |
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| CN (1) | CN103479533B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104490617A (en) * | 2014-11-24 | 2015-04-08 | 佛山市金骏康健康科技有限公司 | Applications of dihydrochalcone and dihydrochalcone glucoside compound as active ingredients used for whitening skin and improving dark and gloomy skin |
| CN106473961A (en) * | 2016-12-02 | 2017-03-08 | 丹东康齿灵保洁用品有限公司 | A kind of gargarism and preparation method |
| CN108125813A (en) * | 2018-01-17 | 2018-06-08 | 卢鹤文 | Tooth liquid is gargled in a kind of bactericidal antiphlogistic detumescence |
| CN112773848A (en) * | 2021-02-03 | 2021-05-11 | 安徽中医药大学 | Traditional Chinese medicine formula freeze-dried quick-release tablet for treating halitosis and preparation method thereof |
-
2013
- 2013-09-11 CN CN201310413455.1A patent/CN103479533B/en not_active Expired - Fee Related
Non-Patent Citations (4)
| Title |
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| 吴天祥等: ""甘草甜素的用途"", 《现代化工》, no. 7, 31 December 1996 (1996-12-31), pages 49 - 50 * |
| 覃青云等: ""柚皮苷在口腔护理用品中的应用研究"", 《牙膏工业》, vol. 19, no. 2, 30 June 2009 (2009-06-30), pages 25 - 29 * |
| 赵煜，等: "纯天然丹皮酚含漱液", 《口腔护理用品工业》, vol. 20, no. 2, 30 April 2010 (2010-04-30), pages 19 - 21 * |
| 黄秀凤: ""中药提取物及其化学成分抑菌作用的研究进展"", 《中国药物与临床》, vol. 7, no. 5, 31 May 2007 (2007-05-31), pages 370 - 371 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104490617A (en) * | 2014-11-24 | 2015-04-08 | 佛山市金骏康健康科技有限公司 | Applications of dihydrochalcone and dihydrochalcone glucoside compound as active ingredients used for whitening skin and improving dark and gloomy skin |
| CN104490617B (en) * | 2014-11-24 | 2017-06-16 | 佛山市金骏康健康科技有限公司 | Dihydrochalcone glucosides is used as whitening, the purposes of the dark and gloomy skin quality active ingredient of improvement |
| CN106473961A (en) * | 2016-12-02 | 2017-03-08 | 丹东康齿灵保洁用品有限公司 | A kind of gargarism and preparation method |
| CN108125813A (en) * | 2018-01-17 | 2018-06-08 | 卢鹤文 | Tooth liquid is gargled in a kind of bactericidal antiphlogistic detumescence |
| CN112773848A (en) * | 2021-02-03 | 2021-05-11 | 安徽中医药大学 | Traditional Chinese medicine formula freeze-dried quick-release tablet for treating halitosis and preparation method thereof |
| CN112773848B (en) * | 2021-02-03 | 2022-04-08 | 安徽中医药大学 | Traditional Chinese medicine formula freeze-dried quick-release tablet for treating halitosis and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN103479533B (en) | 2016-08-10 |
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Effective date of registration: 20180328 Address after: 515100, Guangdong, Shantou Province, Sima, Hong Kong, Hong Kong, Hong Kong, Hulu Industrial Zone, four street, a building Patentee after: GUANGDONG SANJIAO DAILYCHEMICAL Co.,Ltd. Address before: 201107 Shanghai city Minhang District Minhang Road 88 Lane No. 1-30 building twenty-second room T159 Patentee before: SHANGHAI FANGMU FINE CHEMICAL Co.,Ltd. |
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160810 |