CN1883443B - A health buccal spray and method for preparing same - Google Patents
A health buccal spray and method for preparing same Download PDFInfo
- Publication number
- CN1883443B CN1883443B CN200510035385A CN200510035385A CN1883443B CN 1883443 B CN1883443 B CN 1883443B CN 200510035385 A CN200510035385 A CN 200510035385A CN 200510035385 A CN200510035385 A CN 200510035385A CN 1883443 B CN1883443 B CN 1883443B
- Authority
- CN
- China
- Prior art keywords
- pure
- purified water
- formula proportion
- magnolol
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims abstract description 4
- 239000007921 spray Substances 0.000 title claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 18
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 claims abstract description 14
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000008213 purified water Substances 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 238000005303 weighing Methods 0.000 claims abstract description 8
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 7
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 6
- 239000000600 sorbitol Substances 0.000 claims abstract description 6
- 238000003756 stirring Methods 0.000 claims abstract description 4
- 230000001476 alcoholic effect Effects 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 6
- 235000013877 carbamide Nutrition 0.000 claims description 6
- 239000004202 carbamide Substances 0.000 claims description 6
- 239000010977 jade Substances 0.000 claims description 6
- 239000000243 solution Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 4
- 238000012856 packing Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002994 raw material Substances 0.000 abstract description 7
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract 1
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 abstract 1
- 229920006097 Ultramide® Polymers 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 229940041616 menthol Drugs 0.000 abstract 1
- 239000003595 mist Substances 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
- 229960003500 triclosan Drugs 0.000 abstract 1
- 229940054376 ultra mide Drugs 0.000 abstract 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 8
- 208000007117 Oral Ulcer Diseases 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 230000001954 sterilising effect Effects 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 3
- 208000003265 stomatitis Diseases 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 1
- 208000003445 Mouth Neoplasms Diseases 0.000 description 1
- 206010028034 Mouth ulceration Diseases 0.000 description 1
- 208000006595 Necrotizing Ulcerative Gingivitis Diseases 0.000 description 1
- 208000025157 Oral disease Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 208000030194 mouth disease Diseases 0.000 description 1
- 210000003254 palate Anatomy 0.000 description 1
- 208000028169 periodontal disease Diseases 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 201000008587 ulcerative stomatitis Diseases 0.000 description 1
Abstract
Disclosed is a mist for oral health which comprises the constituents of triclosan 0.01-15%, menthol 0.005-8%, magnolol 0.01-17%, sorbitol (70%) 1-30%, ultramide 0.1-10%, ethanol 10-50%, and purified water 40-95%. The preparing process consists of weighing raw materials proportionally, loading alcohol soluble raw materials and water-soluble raw materials into different containers, charging ethanoland purified water for dissolution, mixing the solutions, stirring, solubilizing, filtering and split charging.
Description
Technical field
The invention belongs to a kind of technical field of utilizing the oral health product that natural plants purification thing and high-efficiency broad spectrum antibacterial make for primary raw material.
Background technology
China people oral healthy condition is very poor at present, and nearly 20% people (2.6 hundred million) suffers from stomatitis, oral ulcer, and the oral ulcer sickness rate is only second to dental caries and periodontal disease.Oral ulcer claims ulcerative stomatitis, aphtha again, it is common oral disease, cause by pathogenic infections such as streptococcus, staphylococcus aureus, bacillus pyocyaneus that mainly ulcer often betides mucosa in tongue, the cheek, the interior mucosa of lip and palate, also can spread to bicker and throat sometimes.Oral ulcer does not heal for a long time, may develop into oral cancer, and the oral ulcer canceration rate is 3-5% according to statistics.Stomatitis, oral ulcer make us agonizing even uneasy in either sitting or lying, sleeping and eating not peaceful, depressed, influenced people's quality of life and health status significantly.
At present, the oral disinfecting product of being sold on the market, a class is: contain the enzyme product, because of the unstable characteristics of enzyme itself, lose effect easily; Another kind ofly be: pure Chinese medicinal preparation, but action effect is slower.
The present invention adopts raw materials such as efficient, quick-acting broad spectrum antimicrobicides and natural medicinal plant sterilization component, scientific composition, has the double sterilization effect, can suppress and kill oral cavity pathogen fast, and can prevent the chemical sproof generation of pathogenic bacteria, stomatitis, oral ulcer, periodontitis, gingivitis etc. there are good effect.Be ideal oral health articles for use.
Summary of the invention
Technical problem to be solved by this invention is:
Adopt natural medicinal plant sterilization component and high-efficiency broad spectrum antibacterial, carry out scientific composition, make to have the double sterilization effect, can suppress fast and kill oral cavity pathogen, prevent that pathogenic bacterium from producing drug resistance, and increase permeance property, improve effect.
Technical scheme of the present invention is:
1, the composition proportion of oral health spray:
Pure as jade pure 0.01～15% magnolol, 0.01～17% Mentholum, 0.005～8% sorbitol (70%) 1～30% carbamide, 0.1～10% ethanol, 10～50% purified water 40～95%.
2, process:
Press each raw material of formula proportion weighing, pure dissolubility raw material is inserted in the container, add ethanol, make it fully dissolving and make alcoholic solution; Water-soluble material is inserted another container, add purified water, make it fully dissolving and make aqueous solution, then alcoholic solution is slowly added in the aqueous solution, stir, solubilising filters, and packing forms.
The specific embodiment
1, takes by weighing respectively by formula proportion: pure as jade pure 0.01～8% magnolol, 0.01～7% Mentholum, 0.01～5% sorbitol (70%) 2～25% carbamide, 0.2～8% ethanol, 12～40% purified water 40～85%.
2, pure as jade pure, Mentholum, magnolol are inserted in the container, add ethanol, make it fully dissolving and make alcoholic solution; Sorbitol (70%), carbamide are inserted another container, add purified water, make it fully dissolving and make aqueous solution, then alcoholic solution is slowly added in the aqueous solution, stir, solubilising filters, and packing forms.
Claims (2)
1. oral health spray, it is characterized in that by pure as jade pure, magnolol, Mentholum, content being that 70% mountain plough alcohol, carbamide, ethanol, purified water are formed, its each composition by formula proportion take by weighing respectively for: pure as jade pure 0.01～8%, magnolol 0.01～7%, Mentholum 0.01～5%, content are 70% sorbitol 2～25%, carbamide 0.2～8%, ethanol 12～40%, purified water 40～85%.
2. the manufacture method of an oral health spray, it is characterized by: will insert in the container by pure as jade pure 0.01～8%, Mentholum 0.01～5%, magnolol 0.01～7% that formula proportion takes by weighing respectively, adding makes it fully dissolving and makes alcoholic solution by the ethanol 12～40% that formula proportion takes by weighing; The content that will take by weighing respectively by formula proportion is that 70% sorbitol 2～25%, carbamide 0.2～8% are inserted another container, the purified water 40～85% that adding takes by weighing by formula proportion, make it fully dissolving and make aqueous solution, slowly add alcoholic solution in the aqueous solution then, stir, solubilising filters, and packing forms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200510035385A CN1883443B (en) | 2005-06-24 | 2005-06-24 | A health buccal spray and method for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200510035385A CN1883443B (en) | 2005-06-24 | 2005-06-24 | A health buccal spray and method for preparing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1883443A CN1883443A (en) | 2006-12-27 |
| CN1883443B true CN1883443B (en) | 2010-05-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200510035385A Expired - Fee Related CN1883443B (en) | 2005-06-24 | 2005-06-24 | A health buccal spray and method for preparing same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1883443B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017206015A1 (en) * | 2016-05-30 | 2017-12-07 | 江苏奇力康皮肤药业有限公司 | Long-lasting antibacterial and tooth protection gargle |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225261A (en) * | 1998-04-15 | 1999-08-11 | 贾灏 | Full effective anti dental plaque tooth paste |
| CN1441664A (en) * | 2000-05-10 | 2003-09-10 | 高露洁-棕榄公司 | Synergistic antiplaque/antigivitis oral composition |
| CN1459301A (en) * | 2002-05-21 | 2003-12-03 | 王德英 | Traditional Chinese medicinal plaster for treating cold |
| WO2004000235A2 (en) * | 2002-06-25 | 2003-12-31 | Wm. Wrigley Jr. Company | Breath freshening and oral cleansing product with magnolia bark extract |
| CN1561952A (en) * | 2004-04-15 | 2005-01-12 | 上海交通大学 | Mitalan gargle effervescence tablet for gargle liquid and its preparing method |
-
2005
- 2005-06-24 CN CN200510035385A patent/CN1883443B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225261A (en) * | 1998-04-15 | 1999-08-11 | 贾灏 | Full effective anti dental plaque tooth paste |
| CN1441664A (en) * | 2000-05-10 | 2003-09-10 | 高露洁-棕榄公司 | Synergistic antiplaque/antigivitis oral composition |
| CN1459301A (en) * | 2002-05-21 | 2003-12-03 | 王德英 | Traditional Chinese medicinal plaster for treating cold |
| WO2004000235A2 (en) * | 2002-06-25 | 2003-12-31 | Wm. Wrigley Jr. Company | Breath freshening and oral cleansing product with magnolia bark extract |
| CN1561952A (en) * | 2004-04-15 | 2005-01-12 | 上海交通大学 | Mitalan gargle effervescence tablet for gargle liquid and its preparing method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1883443A (en) | 2006-12-27 |
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| C14 | Grant of patent or utility model | ||
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Owner name: GUANGZHOU FUTUOKANG BIOLOGICAL TECHNOLOGY CO., LTD Free format text: FORMER OWNER: GUO ZIJIE Effective date: 20150722 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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Effective date of registration: 20150722 Address after: Haizhuqu District Chigang road Guangzhou city Guangdong province 510310 No. 275 room 902 Patentee after: Guangzhou Futuo Kang Biotechnology Co. Ltd. Address before: Haizhuqu District Chigang road Guangzhou city Guangdong province 510310 No. 275 room 902 Patentee before: Guo Zijie |
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| CF01 | Termination of patent right due to non-payment of annual fee |