CN1759189A - 切向流过滤方法及其装置 - Google Patents
切向流过滤方法及其装置 Download PDFInfo
- Publication number
- CN1759189A CN1759189A CN03826243.6A CN03826243A CN1759189A CN 1759189 A CN1759189 A CN 1759189A CN 03826243 A CN03826243 A CN 03826243A CN 1759189 A CN1759189 A CN 1759189A
- Authority
- CN
- China
- Prior art keywords
- milk
- filtration
- membrane
- feed liquid
- permeate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Water Supply & Treatment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44978603P | 2003-02-24 | 2003-02-24 | |
| US60/449,786 | 2003-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1759189A true CN1759189A (zh) | 2006-04-12 |
Family
ID=32927567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN03826243.6A Pending CN1759189A (zh) | 2003-02-24 | 2003-08-06 | 切向流过滤方法及其装置 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20040167320A1 (enExample) |
| EP (1) | EP1601788A4 (enExample) |
| JP (1) | JP2006515227A (enExample) |
| CN (1) | CN1759189A (enExample) |
| AU (1) | AU2003261387A1 (enExample) |
| CA (1) | CA2516836A1 (enExample) |
| RU (1) | RU2005129745A (enExample) |
| WO (1) | WO2004076695A1 (enExample) |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011110073A1 (zh) * | 2010-03-08 | 2011-09-15 | 北京清大天一科技有限公司 | 细胞培养混合物的分离纯化方法 |
| CN104755489A (zh) * | 2012-10-30 | 2015-07-01 | 弗·哈夫曼-拉罗切有限公司 | 使用双级切线流超滤纯化多肽 |
| CN104968408A (zh) * | 2013-02-05 | 2015-10-07 | 普凯尔德诊断技术有限公司 | 过滤装置以及使用该过滤装置的方法 |
| CN106188300A (zh) * | 2015-05-07 | 2016-12-07 | 温州市人民医院 | 一种保持胱抑素c抗体-胶乳共价偶联复合物活性的快速纯化方法 |
| CN106457153A (zh) * | 2014-03-07 | 2017-02-22 | 新加坡科技研究局 | 用于分级分离生物制品的装置和方法 |
| CN106457302A (zh) * | 2014-05-27 | 2017-02-22 | 人工细胞科技公司 | 通过tff进行多层涂覆芯的自动化逐层构造 |
| CN106794295A (zh) * | 2014-08-21 | 2017-05-31 | 查尔斯斯塔克布料实验室公司 | 用于增加微流体装置中不期望的颗粒的对流清除的系统和方法 |
| CN107320765A (zh) * | 2016-04-29 | 2017-11-07 | 深圳兰度生物材料有限公司 | 一种重组纤维结构胶原蛋白海绵的制备方法 |
| CN107907643A (zh) * | 2017-11-10 | 2018-04-13 | 福建省水产研究所 | 一种测定天然海水中溶解相、纳米相和真溶液相中有机碳和无机氮含量的方法 |
| CN110241012A (zh) * | 2018-03-09 | 2019-09-17 | 嘉和生物药业有限公司 | 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用 |
| CN110607272A (zh) * | 2019-09-23 | 2019-12-24 | 山东甲骨文生物科技有限公司 | 一种哺乳动物细胞培养液的添加剂及细胞培养液 |
| CN113518655A (zh) * | 2019-01-30 | 2021-10-19 | 瑞普利金公司 | 使用径迹蚀刻膜过滤生物流体的方法 |
| US11369722B2 (en) | 2013-01-11 | 2022-06-28 | The Charles Stark Draper Laboratory Inc. | Systems and methods for increasing convective clearance of undesired particles in a microfluidic device |
| CN116328553A (zh) * | 2022-11-16 | 2023-06-27 | 安徽百奥秘科生物医药研究院有限公司 | 一种过滤膜及一步过滤快速提取核酸装置及提取核酸方法 |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030005468A1 (en) * | 1998-06-19 | 2003-01-02 | Meade Harry M. | Methods and vectors for improving nucleic acid expression |
| US20040226052A1 (en) * | 2000-10-13 | 2004-11-11 | Meade Harry M. | Methods of producing a target molecule in a transgenic animal and purification of the target molecule |
| WO2005073732A2 (en) * | 2004-01-23 | 2005-08-11 | Amgen Inc. | Lc/ms method of analyzing high molecular weight proteins |
| US20050197496A1 (en) * | 2004-03-04 | 2005-09-08 | Gtc Biotherapeutics, Inc. | Methods of protein fractionation using high performance tangential flow filtration |
| WO2005119126A1 (fr) * | 2004-05-28 | 2005-12-15 | Alstom Technology Ltd | Dispositif a lit fluidise a agent comburant enrichi en oxygene |
| US20060051347A1 (en) * | 2004-09-09 | 2006-03-09 | Winter Charles M | Process for concentration of antibodies and therapeutic products thereof |
| AU2011203578B2 (en) * | 2004-09-30 | 2012-10-11 | Bayer Healthcare Llc | Devices and methods for integrated continuous manufacturing of biological molecules |
| JP5579966B2 (ja) * | 2004-09-30 | 2014-08-27 | バイヤー ヘルスケア エルエルシー | 生体分子の一貫連続製造のための装置及び方法 |
| US20060130159A1 (en) * | 2004-12-09 | 2006-06-15 | Nick Masiello | Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum |
| US7531632B2 (en) * | 2006-02-16 | 2009-05-12 | Gtc Biotherapeutics, Inc. | Clarification of transgenic milk using depth filtration |
| DK2007506T3 (da) | 2006-03-31 | 2014-06-16 | Danisco Us Inc | Tangentialstrømningsfiltreringsapparater, -systemer og -fremgangsmådertil separering af forbindelser |
| FR2901796A1 (fr) * | 2006-05-31 | 2007-12-07 | Lab Francais Du Fractionnement | Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait |
| FR2901707B1 (fr) | 2006-05-31 | 2017-09-29 | Lab Francais Du Fractionnement | Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis |
| US20080160134A1 (en) * | 2006-12-27 | 2008-07-03 | Jamie Allen Hestekin | Method Of Producing Concentrated Liquid Dairy Products |
| FR2910786B1 (fr) | 2006-12-29 | 2017-08-11 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies (Lfb) | "procede d'extraction d'une proteine presente dans du lait" |
| GB0711327D0 (en) * | 2007-06-12 | 2007-07-25 | Hansa Medical Ab | Diagnostic method |
| AU2008277886B8 (en) | 2007-07-17 | 2013-08-01 | F. Hoffmann-La Roche Ag | Variable tangential flow filtration |
| JP5205470B2 (ja) * | 2007-11-29 | 2013-06-05 | エフ.ホフマン−ラ ロシュ アーゲー | 免疫グロブリン凝集物 |
| JP5717625B2 (ja) * | 2008-05-14 | 2015-05-13 | アグリカルチャー ヴィクトリア サービス ピーティーワイ エルティーディーAgriculture Victoria Services Pty Ltd | アンギオゲニン濃縮ミルク分画 |
| JP5762951B2 (ja) * | 2008-05-15 | 2015-08-12 | ダブリュ.・ヘルス・エル.ピー.W. Health L.P. | 分泌性免疫グロブリンの豊富な乳画分の製造方法 |
| US9055752B2 (en) | 2008-11-06 | 2015-06-16 | Intercontinental Great Brands Llc | Shelf-stable concentrated dairy liquids and methods of forming thereof |
| UA112972C2 (uk) | 2010-09-08 | 2016-11-25 | Інтерконтінентал Грейт Брендс ЛЛС | Рідкий молочний концентрат з високим вмістом сухих речовин |
| JP6189751B2 (ja) | 2010-12-30 | 2017-08-30 | ラボラトワール フランセ デュ フラクショヌマン エ デ ビオテクノロジーLaboratoire Francais du Fractionnement et des Biotechnologies | 病原体不活性化剤としてのグリコール |
| US8840790B2 (en) * | 2011-04-27 | 2014-09-23 | Fenwal, Inc. | Systems and methods of controlling fouling during a filtration procedure |
| JP6363017B2 (ja) | 2011-09-01 | 2018-07-25 | 中外製薬株式会社 | 限外ろ過によって高度に濃縮された抗体を含む組成物を調製するための方法 |
| EP2885392A1 (en) * | 2012-08-20 | 2015-06-24 | Terumo BCT, Inc. | Concentrating components of fluid circulated through a cell growth chamber |
| JP2016508515A (ja) | 2013-02-13 | 2016-03-22 | ラボラトワール フランセ デュ フラクショヌマン エ デ ビオテクノロジーLaboratoire Francais du Fractionnement et des Biotechnologies | 高ガラクトシル化抗TNF−α抗体およびその使用 |
| US10034921B2 (en) | 2013-02-13 | 2018-07-31 | Laboratoire Français Du Fractionnement Et Des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| EA201591229A1 (ru) | 2013-03-14 | 2016-01-29 | Шир Хьюман Дженетик Терапис, Инк. | Способы очистки матричной рнк |
| AU2014285971A1 (en) | 2013-07-05 | 2016-02-04 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Affinity chromatography matrix |
| EP2907565A1 (de) * | 2014-02-17 | 2015-08-19 | Bayer Technology Services GmbH | Dialyse-Einheit zum kontinuierlichen Puffer- bzw. Medienaustausch aus einer Proteinlösung |
| CN112588116A (zh) | 2014-05-13 | 2021-04-02 | 美国安进公司 | 用于过滤器和过滤过程的过程控制系统和方法 |
| ES2926985T3 (es) | 2014-05-15 | 2022-10-31 | Insmed Inc | Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas |
| WO2015195452A2 (en) * | 2014-06-16 | 2015-12-23 | Emd Millipore Corporation | Single-pass filtration systems and processes |
| EP4144434B1 (en) * | 2014-06-16 | 2024-04-17 | EMD Millipore Corporation | Single-pass filtration systems and processes |
| EP2957335B1 (en) * | 2014-06-16 | 2020-05-27 | EMD Millipore Corporation | Single-pass filtration systems and processes |
| WO2015195453A2 (en) | 2014-06-16 | 2015-12-23 | Emd Millipore Corporation | Methods for increasing the capacity of flow-through processes |
| KR101938948B1 (ko) | 2014-06-25 | 2019-01-15 | 이엠디 밀리포어 코포레이션 | 밀집한 나권형 필터 엘리먼트, 모듈 및 시스템 |
| WO2016033553A1 (en) | 2014-08-29 | 2016-03-03 | Emd Millipore Corporation | Processes for filtering liquids using single pass tangential flow filtration systems and tangential flow filtration systems with recirculation of retentate |
| WO2016033546A1 (en) | 2014-08-29 | 2016-03-03 | Emd Millipore Corporation | Single pass tangential flow filtration systems and tangential flow filtration systems with recirculation of retentate |
| DK4108769T3 (da) | 2015-05-29 | 2023-10-09 | Curevac Mfg Gmbh | Fremgangsmåde til fremstilling og oprensning af rna, omfattende mindst et trin til tangential-flow-filtrering |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| US12226737B2 (en) | 2016-06-09 | 2025-02-18 | Emd Millipore Corporation | Radial-path filter elements, systems and methods of using same |
| BR102017001309A2 (pt) * | 2017-01-23 | 2018-08-14 | Fundação Oswaldo Cruz | vacina recombinante para helmintos em pichia pastoris, e, processos de produção e purificação de proteína como vacina para helmintos |
| WO2019084178A1 (en) * | 2017-10-24 | 2019-05-02 | Cerahelix, Inc. | SYSTEMS AND METHODS FOR MULTI-STAGE FLUID SEPARATION |
| EP3773505A4 (en) | 2018-03-30 | 2021-12-22 | Insmed Incorporated | PROCESS FOR THE CONTINUOUS MANUFACTURING OF LIPOSOMAL MEDICINAL PRODUCTS |
| EP3794013B1 (en) | 2018-05-17 | 2024-02-21 | CSL Behring AG | Method and system of protein extraction |
| US12285723B2 (en) * | 2019-10-01 | 2025-04-29 | Tetra Laval Holdings & Finance S.A. | Method for filtering a dairy product |
| JP2023502412A (ja) * | 2019-11-20 | 2023-01-24 | ツェー・エス・エル・ベーリング・アクチエンゲゼルシャフト | 沈殿物からタンパク質を抽出する方法および不純物を沈殿させる方法 |
| CN111018968B (zh) * | 2019-12-16 | 2021-07-27 | 兴盟生物医药(苏州)有限公司 | 一种通过超滤浓缩制备高浓度抗体制剂的方法 |
| KR20230024891A (ko) * | 2020-06-11 | 2023-02-21 | 2세븐티 바이오, 인코포레이티드 | 바이러스 벡터 제조 방법 |
| CN113713621B (zh) * | 2021-08-26 | 2022-08-02 | 杭州纽创生物检测有限公司 | 一种应用于病毒的sptff装置、灌注系统及病毒料液过滤方法 |
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| US4888115A (en) * | 1983-12-29 | 1989-12-19 | Cuno, Incorporated | Cross-flow filtration |
| US4874516A (en) * | 1984-12-29 | 1989-10-17 | Ngk Insulators, Ltd. | A ceramic filter for semi-ultrafiltration |
| US5948441A (en) * | 1988-03-07 | 1999-09-07 | The Liposome Company, Inc. | Method for size separation of particles |
| US5256294A (en) * | 1990-09-17 | 1993-10-26 | Genentech, Inc. | Tangential flow filtration process and apparatus |
| SE470375B (sv) * | 1992-05-07 | 1994-02-07 | Alfa Laval Food Eng Ab | Sätt att erhålla högvärdiga proteinprodukter ur vassle |
| US5356651A (en) * | 1992-12-30 | 1994-10-18 | Pall Corporation | Manufacturing method for producing sterile milk using dynamic microfiltration |
| US5518624A (en) * | 1994-05-06 | 1996-05-21 | Illinois Water Treatment, Inc. | Ultra pure water filtration |
| US5585466A (en) * | 1994-12-06 | 1996-12-17 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Crystals of serum albumin for use in genetic engineering and rational drug design |
| US6268487B1 (en) * | 1996-05-13 | 2001-07-31 | Genzyme Transgenics Corporation | Purification of biologically active peptides from milk |
| GB9807464D0 (en) * | 1998-04-07 | 1998-06-10 | Pharming Bv | Purification of human acid µ-glucosidase |
| AU756832B2 (en) * | 1999-02-22 | 2003-01-23 | Ncsrt, Inc. | Purification of biological substances |
| US6984378B1 (en) * | 1999-02-26 | 2006-01-10 | Pfizer, Inc. | Method for the purification, recovery, and sporulation of cysts and oocysts |
-
2003
- 2003-08-06 JP JP2004568846A patent/JP2006515227A/ja not_active Abandoned
- 2003-08-06 RU RU2005129745/13A patent/RU2005129745A/ru not_active Application Discontinuation
- 2003-08-06 EP EP03816097A patent/EP1601788A4/en not_active Withdrawn
- 2003-08-06 WO PCT/US2003/024529 patent/WO2004076695A1/en not_active Ceased
- 2003-08-06 CN CN03826243.6A patent/CN1759189A/zh active Pending
- 2003-08-06 US US10/635,117 patent/US20040167320A1/en not_active Abandoned
- 2003-08-06 AU AU2003261387A patent/AU2003261387A1/en not_active Abandoned
- 2003-08-06 CA CA002516836A patent/CA2516836A1/en not_active Abandoned
-
2005
- 2005-07-21 US US11/191,280 patent/US20050260672A1/en not_active Abandoned
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011110073A1 (zh) * | 2010-03-08 | 2011-09-15 | 北京清大天一科技有限公司 | 细胞培养混合物的分离纯化方法 |
| CN104755489A (zh) * | 2012-10-30 | 2015-07-01 | 弗·哈夫曼-拉罗切有限公司 | 使用双级切线流超滤纯化多肽 |
| CN104755489B (zh) * | 2012-10-30 | 2019-01-15 | 弗·哈夫曼-拉罗切有限公司 | 使用双级切线流超滤纯化多肽 |
| US11369722B2 (en) | 2013-01-11 | 2022-06-28 | The Charles Stark Draper Laboratory Inc. | Systems and methods for increasing convective clearance of undesired particles in a microfluidic device |
| CN104968408A (zh) * | 2013-02-05 | 2015-10-07 | 普凯尔德诊断技术有限公司 | 过滤装置以及使用该过滤装置的方法 |
| CN104968408B (zh) * | 2013-02-05 | 2019-09-17 | 普凯尔德诊断技术有限公司 | 过滤装置以及使用该过滤装置的方法 |
| CN106457153B (zh) * | 2014-03-07 | 2019-03-29 | 新加坡科技研究局 | 用于分级分离生物制品的装置和方法 |
| CN106457153A (zh) * | 2014-03-07 | 2017-02-22 | 新加坡科技研究局 | 用于分级分离生物制品的装置和方法 |
| CN106457302A (zh) * | 2014-05-27 | 2017-02-22 | 人工细胞科技公司 | 通过tff进行多层涂覆芯的自动化逐层构造 |
| CN106457302B (zh) * | 2014-05-27 | 2020-04-17 | 人工细胞科技公司 | 通过tff进行多层涂覆芯的自动化逐层构造 |
| CN106794295A (zh) * | 2014-08-21 | 2017-05-31 | 查尔斯斯塔克布料实验室公司 | 用于增加微流体装置中不期望的颗粒的对流清除的系统和方法 |
| CN106188300A (zh) * | 2015-05-07 | 2016-12-07 | 温州市人民医院 | 一种保持胱抑素c抗体-胶乳共价偶联复合物活性的快速纯化方法 |
| CN107320765A (zh) * | 2016-04-29 | 2017-11-07 | 深圳兰度生物材料有限公司 | 一种重组纤维结构胶原蛋白海绵的制备方法 |
| CN107907643A (zh) * | 2017-11-10 | 2018-04-13 | 福建省水产研究所 | 一种测定天然海水中溶解相、纳米相和真溶液相中有机碳和无机氮含量的方法 |
| CN110241012A (zh) * | 2018-03-09 | 2019-09-17 | 嘉和生物药业有限公司 | 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用 |
| CN113518655A (zh) * | 2019-01-30 | 2021-10-19 | 瑞普利金公司 | 使用径迹蚀刻膜过滤生物流体的方法 |
| CN113518655B (zh) * | 2019-01-30 | 2023-02-17 | 瑞普利金公司 | 使用径迹蚀刻膜过滤生物流体的方法 |
| CN110607272A (zh) * | 2019-09-23 | 2019-12-24 | 山东甲骨文生物科技有限公司 | 一种哺乳动物细胞培养液的添加剂及细胞培养液 |
| CN116328553A (zh) * | 2022-11-16 | 2023-06-27 | 安徽百奥秘科生物医药研究院有限公司 | 一种过滤膜及一步过滤快速提取核酸装置及提取核酸方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004076695A1 (en) | 2004-09-10 |
| EP1601788A1 (en) | 2005-12-07 |
| JP2006515227A (ja) | 2006-05-25 |
| RU2005129745A (ru) | 2006-03-20 |
| US20040167320A1 (en) | 2004-08-26 |
| CA2516836A1 (en) | 2004-09-10 |
| EP1601788A4 (en) | 2006-11-15 |
| AU2003261387A1 (en) | 2004-09-17 |
| US20050260672A1 (en) | 2005-11-24 |
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