CA2516836A1 - Methods of tangential flow filtration and an apparatus therefore - Google Patents
Methods of tangential flow filtration and an apparatus therefore Download PDFInfo
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- CA2516836A1 CA2516836A1 CA002516836A CA2516836A CA2516836A1 CA 2516836 A1 CA2516836 A1 CA 2516836A1 CA 002516836 A CA002516836 A CA 002516836A CA 2516836 A CA2516836 A CA 2516836A CA 2516836 A1 CA2516836 A1 CA 2516836A1
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- 210000002700 urine Anatomy 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 235000008939 whole milk Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Water Supply & Treatment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44978603P | 2003-02-24 | 2003-02-24 | |
| US60/449,786 | 2003-02-24 | ||
| PCT/US2003/024529 WO2004076695A1 (en) | 2003-02-24 | 2003-08-06 | Methods of tangential flow filtration and an apparatus therefore |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2516836A1 true CA2516836A1 (en) | 2004-09-10 |
Family
ID=32927567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002516836A Abandoned CA2516836A1 (en) | 2003-02-24 | 2003-08-06 | Methods of tangential flow filtration and an apparatus therefore |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20040167320A1 (enExample) |
| EP (1) | EP1601788A4 (enExample) |
| JP (1) | JP2006515227A (enExample) |
| CN (1) | CN1759189A (enExample) |
| AU (1) | AU2003261387A1 (enExample) |
| CA (1) | CA2516836A1 (enExample) |
| RU (1) | RU2005129745A (enExample) |
| WO (1) | WO2004076695A1 (enExample) |
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|---|---|---|---|---|
| US20030005468A1 (en) * | 1998-06-19 | 2003-01-02 | Meade Harry M. | Methods and vectors for improving nucleic acid expression |
| US20040226053A1 (en) * | 2000-10-13 | 2004-11-11 | Meade Harry M. | Methods of producing a target molecule in a transgenic animal and purification of the target molecule |
| US7329353B2 (en) * | 2004-01-23 | 2008-02-12 | Amgen Inc. | LC/MS method of analyzing high molecular weight proteins |
| US20050197496A1 (en) * | 2004-03-04 | 2005-09-08 | Gtc Biotherapeutics, Inc. | Methods of protein fractionation using high performance tangential flow filtration |
| PL1753999T3 (pl) * | 2004-05-28 | 2014-05-30 | General Electric Technology Gmbh | Urządzenie ze złożem fluidalnym z utleniaczem wzbogaconym w tlen |
| US20060051347A1 (en) * | 2004-09-09 | 2006-03-09 | Winter Charles M | Process for concentration of antibodies and therapeutic products thereof |
| AU2011203578B2 (en) * | 2004-09-30 | 2012-10-11 | Bayer Healthcare Llc | Devices and methods for integrated continuous manufacturing of biological molecules |
| EP1807101B1 (en) * | 2004-09-30 | 2016-04-13 | Bayer Healthcare LLC | Devices and methods for integrated continuous manufacturing of biological molecules |
| US20060130159A1 (en) * | 2004-12-09 | 2006-06-15 | Nick Masiello | Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum |
| US7531632B2 (en) * | 2006-02-16 | 2009-05-12 | Gtc Biotherapeutics, Inc. | Clarification of transgenic milk using depth filtration |
| WO2007120449A1 (en) * | 2006-03-31 | 2007-10-25 | Genencor International, Inc. | Tangential flow filtration apparatuses, systems, and processes for the separation of compounds |
| FR2901796A1 (fr) * | 2006-05-31 | 2007-12-07 | Lab Francais Du Fractionnement | Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait |
| FR2901707B1 (fr) | 2006-05-31 | 2017-09-29 | Lab Francais Du Fractionnement | Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis |
| US20080160134A1 (en) * | 2006-12-27 | 2008-07-03 | Jamie Allen Hestekin | Method Of Producing Concentrated Liquid Dairy Products |
| FR2910786B1 (fr) | 2006-12-29 | 2017-08-11 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies (Lfb) | "procede d'extraction d'une proteine presente dans du lait" |
| GB0711327D0 (en) * | 2007-06-12 | 2007-07-25 | Hansa Medical Ab | Diagnostic method |
| RU2504549C2 (ru) * | 2007-07-17 | 2014-01-20 | Ф.Хоффманн-Ля Рош Аг | Фильтрация в переменном тангенциальном потоке |
| CA2706403A1 (en) * | 2007-11-29 | 2009-06-04 | F. Hoffmann-La Roche Ag | Immunoglobulin aggregates |
| JP5717625B2 (ja) * | 2008-05-14 | 2015-05-13 | アグリカルチャー ヴィクトリア サービス ピーティーワイ エルティーディーＡｇｒｉｃｕｌｔｕｒｅ Ｖｉｃｔｏｒｉａ Ｓｅｒｖｉｃｅｓ Ｐｔｙ Ｌｔｄ | アンギオゲニン濃縮ミルク分画 |
| DK2280999T3 (da) * | 2008-05-15 | 2017-11-13 | Biosys Health Inc | Fremgangsmåde til fremstilling af mælkefraktioner, som er rige på sekretoriske immunglobuliner |
| US9055752B2 (en) * | 2008-11-06 | 2015-06-16 | Intercontinental Great Brands Llc | Shelf-stable concentrated dairy liquids and methods of forming thereof |
| CN102191226A (zh) * | 2010-03-08 | 2011-09-21 | 北京清大天一科技有限公司 | 细胞培养混合物的分离纯化方法 |
| UA112972C2 (uk) | 2010-09-08 | 2016-11-25 | Інтерконтінентал Грейт Брендс ЛЛС | Рідкий молочний концентрат з високим вмістом сухих речовин |
| WO2012090067A1 (en) | 2010-12-30 | 2012-07-05 | Lfb Biotechnologies | Glycols as pathogen inactivating agents |
| US8840790B2 (en) * | 2011-04-27 | 2014-09-23 | Fenwal, Inc. | Systems and methods of controlling fouling during a filtration procedure |
| AU2012303372A1 (en) | 2011-09-01 | 2014-02-20 | Chugai Seiyaku Kabushiki Kaisha | Method for preparing a composition comprising highly concentrated antibodies by ultrafiltration |
| JP2015526094A (ja) * | 2012-08-20 | 2015-09-10 | テルモ ビーシーティー、インコーポレーテッド | 細胞成長チャンバーを循環する流体の成分を濃縮する方法 |
| SI2914612T1 (sl) * | 2012-10-30 | 2019-03-29 | F. Hoffmann-La Roche Ag | Čiščenje polipeptidov z uporabo dvostopenjske tangencialne ultrafiltracije |
| US10478543B2 (en) | 2013-01-11 | 2019-11-19 | The Charles Stark Draper Laboratory, Inc. | Systems and methods for increasing convective clearance of undesired particles in a microfluidic device |
| US10082452B2 (en) * | 2013-02-05 | 2018-09-25 | Pocared Diagnostics Ltd. | Filter arrangement and method for using the same |
| EP3594230A1 (en) | 2013-02-13 | 2020-01-15 | Laboratoire Français du Fractionnement et des Biotechnologies | Highly galactosylated anti-tnf-alpha antibodies and uses thereof |
| WO2014140927A2 (en) | 2013-02-13 | 2014-09-18 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Proteins with modified glycosylation and methods of production thereof |
| JP6586075B2 (ja) | 2013-03-14 | 2019-10-02 | トランスレイト バイオ， インコーポレイテッド | メッセンジャーｒｎａの精製方法 |
| ES2793176T3 (es) | 2013-07-05 | 2020-11-13 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies Sa | Matriz de cromografía de afinidad |
| EP2907565A1 (de) * | 2014-02-17 | 2015-08-19 | Bayer Technology Services GmbH | Dialyse-Einheit zum kontinuierlichen Puffer- bzw. Medienaustausch aus einer Proteinlösung |
| US20170173537A1 (en) * | 2014-03-07 | 2017-06-22 | Agency For Science, Technology And Research | Apparatus and methods for fractionation of biological products |
| CN112588116A (zh) | 2014-05-13 | 2021-04-02 | 美国安进公司 | 用于过滤器和过滤过程的过程控制系统和方法 |
| CN106535877A (zh) | 2014-05-15 | 2017-03-22 | 英斯梅德股份有限公司 | 用于治疗肺部非结核性分枝杆菌感染的方法 |
| WO2015183716A1 (en) * | 2014-05-27 | 2015-12-03 | Artificial Cell Technologies, Inc. | Automated layer by layer construction of multilayer coated cores by tff |
| WO2015195452A2 (en) * | 2014-06-16 | 2015-12-23 | Emd Millipore Corporation | Single-pass filtration systems and processes |
| EP4144434B1 (en) * | 2014-06-16 | 2024-04-17 | EMD Millipore Corporation | Single-pass filtration systems and processes |
| EP2957335B1 (en) * | 2014-06-16 | 2020-05-27 | EMD Millipore Corporation | Single-pass filtration systems and processes |
| WO2015195453A2 (en) | 2014-06-16 | 2015-12-23 | Emd Millipore Corporation | Methods for increasing the capacity of flow-through processes |
| EP2986361B1 (en) | 2014-06-25 | 2019-06-12 | EMD Millipore Corporation | Compact spiral-wound membrane filter elements |
| WO2016029164A1 (en) * | 2014-08-21 | 2016-02-25 | The Charles Stark Draper Laboratory, Inc. | Systems and methods for increasing convective clearance of undesired particles in a microfluidic device |
| SG11201508664VA (en) | 2014-08-29 | 2016-03-30 | Emd Millipore Corp | Single Pass Tangential Flow Filtration Systems and Tangential Flow Filtration Systems withRecirculation of Retentate |
| CN108325391B (zh) | 2014-08-29 | 2021-05-18 | Emd 密理博公司 | 过滤液体进料的方法 |
| CN106188300A (zh) * | 2015-05-07 | 2016-12-07 | 温州市人民医院 | 一种保持胱抑素c抗体-胶乳共价偶联复合物活性的快速纯化方法 |
| WO2016193206A1 (en) | 2015-05-29 | 2016-12-08 | Curevac Ag | A method for producing and purifying rna, comprising at least one step of tangential flow filtration |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| CN107320765A (zh) * | 2016-04-29 | 2017-11-07 | 深圳兰度生物材料有限公司 | 一种重组纤维结构胶原蛋白海绵的制备方法 |
| ES2925059T3 (es) | 2016-06-09 | 2022-10-13 | Emd Millipore Corp | Elementos de filtro de trayectoria radial, sistemas y métodos de uso de los mismos |
| BR102017001309A2 (pt) * | 2017-01-23 | 2018-08-14 | Fundação Oswaldo Cruz | vacina recombinante para helmintos em pichia pastoris, e, processos de produção e purificação de proteína como vacina para helmintos |
| WO2019084178A1 (en) * | 2017-10-24 | 2019-05-02 | Cerahelix, Inc. | SYSTEMS AND METHODS FOR MULTI-STAGE FLUID SEPARATION |
| CN107907643A (zh) * | 2017-11-10 | 2018-04-13 | 福建省水产研究所 | 一种测定天然海水中溶解相、纳米相和真溶液相中有机碳和无机氮含量的方法 |
| CN110241012B (zh) * | 2018-03-09 | 2022-11-01 | 嘉和生物药业有限公司 | 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用 |
| WO2019191627A1 (en) | 2018-03-30 | 2019-10-03 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| AU2019270458A1 (en) * | 2018-05-17 | 2020-09-24 | Csl Behring Ag | Method and system of protein extraction |
| WO2020160220A1 (en) * | 2019-01-30 | 2020-08-06 | Repligen Corporation | Method of using track etched membranes for the filtration of biological fluids |
| CN110607272B (zh) * | 2019-09-23 | 2022-11-01 | 山东甲骨文生物科技有限公司 | 一种哺乳动物细胞培养液的添加剂及细胞培养液 |
| US12285723B2 (en) * | 2019-10-01 | 2025-04-29 | Tetra Laval Holdings & Finance S.A. | Method for filtering a dairy product |
| US20230002444A1 (en) * | 2019-11-20 | 2023-01-05 | Csl Behring Ag | Method for extracting a protein from a precipitate and method for precipitating impurities |
| CN111018968B (zh) * | 2019-12-16 | 2021-07-27 | 兴盟生物医药(苏州)有限公司 | 一种通过超滤浓缩制备高浓度抗体制剂的方法 |
| WO2021252782A1 (en) * | 2020-06-11 | 2021-12-16 | 2Seventy Bio, Inc. | Methods for manufacturing viral vectors |
| CN113713621B (zh) * | 2021-08-26 | 2022-08-02 | 杭州纽创生物检测有限公司 | 一种应用于病毒的sptff装置、灌注系统及病毒料液过滤方法 |
| CN116328553A (zh) * | 2022-11-16 | 2023-06-27 | 安徽百奥秘科生物医药研究院有限公司 | 一种过滤膜及一步过滤快速提取核酸装置及提取核酸方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4888115A (en) * | 1983-12-29 | 1989-12-19 | Cuno, Incorporated | Cross-flow filtration |
| US4874516A (en) * | 1984-12-29 | 1989-10-17 | Ngk Insulators, Ltd. | A ceramic filter for semi-ultrafiltration |
| US5948441A (en) * | 1988-03-07 | 1999-09-07 | The Liposome Company, Inc. | Method for size separation of particles |
| US5256294A (en) * | 1990-09-17 | 1993-10-26 | Genentech, Inc. | Tangential flow filtration process and apparatus |
| SE470375B (sv) * | 1992-05-07 | 1994-02-07 | Alfa Laval Food Eng Ab | Sätt att erhålla högvärdiga proteinprodukter ur vassle |
| US5356651A (en) * | 1992-12-30 | 1994-10-18 | Pall Corporation | Manufacturing method for producing sterile milk using dynamic microfiltration |
| US5518624A (en) * | 1994-05-06 | 1996-05-21 | Illinois Water Treatment, Inc. | Ultra pure water filtration |
| US5585466A (en) * | 1994-12-06 | 1996-12-17 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Crystals of serum albumin for use in genetic engineering and rational drug design |
| US6268487B1 (en) * | 1996-05-13 | 2001-07-31 | Genzyme Transgenics Corporation | Purification of biologically active peptides from milk |
| GB9807464D0 (en) * | 1998-04-07 | 1998-06-10 | Pharming Bv | Purification of human acid µ-glucosidase |
| WO2000048703A1 (en) * | 1999-02-22 | 2000-08-24 | Henry Kopf | Purification of biological substances |
| US6984378B1 (en) * | 1999-02-26 | 2006-01-10 | Pfizer, Inc. | Method for the purification, recovery, and sporulation of cysts and oocysts |
-
2003
- 2003-08-06 JP JP2004568846A patent/JP2006515227A/ja not_active Abandoned
- 2003-08-06 CN CN03826243.6A patent/CN1759189A/zh active Pending
- 2003-08-06 AU AU2003261387A patent/AU2003261387A1/en not_active Abandoned
- 2003-08-06 US US10/635,117 patent/US20040167320A1/en not_active Abandoned
- 2003-08-06 EP EP03816097A patent/EP1601788A4/en not_active Withdrawn
- 2003-08-06 CA CA002516836A patent/CA2516836A1/en not_active Abandoned
- 2003-08-06 RU RU2005129745/13A patent/RU2005129745A/ru not_active Application Discontinuation
- 2003-08-06 WO PCT/US2003/024529 patent/WO2004076695A1/en not_active Ceased
-
2005
- 2005-07-21 US US11/191,280 patent/US20050260672A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1601788A1 (en) | 2005-12-07 |
| EP1601788A4 (en) | 2006-11-15 |
| WO2004076695A1 (en) | 2004-09-10 |
| JP2006515227A (ja) | 2006-05-25 |
| CN1759189A (zh) | 2006-04-12 |
| US20040167320A1 (en) | 2004-08-26 |
| RU2005129745A (ru) | 2006-03-20 |
| AU2003261387A1 (en) | 2004-09-17 |
| US20050260672A1 (en) | 2005-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |