AU2003261387A1 - Methods of tangential flow filtration and an apparatus therefore - Google Patents

Methods of tangential flow filtration and an apparatus therefore Download PDF

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Publication number
AU2003261387A1
AU2003261387A1 AU2003261387A AU2003261387A AU2003261387A1 AU 2003261387 A1 AU2003261387 A1 AU 2003261387A1 AU 2003261387 A AU2003261387 A AU 2003261387A AU 2003261387 A AU2003261387 A AU 2003261387A AU 2003261387 A1 AU2003261387 A1 AU 2003261387A1
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AU
Australia
Prior art keywords
feedstream
milk
filtration
membrane
membranes
Prior art date
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Abandoned
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AU2003261387A
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English (en)
Inventor
Daniel E. Couto
Amy Laverdiere
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rEVO Biologics Inc
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GTC Biotherapeutics Inc
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Filing date
Publication date
Application filed by GTC Biotherapeutics Inc filed Critical GTC Biotherapeutics Inc
Publication of AU2003261387A1 publication Critical patent/AU2003261387A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Water Supply & Treatment (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)
AU2003261387A 2003-02-24 2003-08-06 Methods of tangential flow filtration and an apparatus therefore Abandoned AU2003261387A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44978603P 2003-02-24 2003-02-24
US60/449,786 2003-02-24
PCT/US2003/024529 WO2004076695A1 (en) 2003-02-24 2003-08-06 Methods of tangential flow filtration and an apparatus therefore

Publications (1)

Publication Number Publication Date
AU2003261387A1 true AU2003261387A1 (en) 2004-09-17

Family

ID=32927567

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003261387A Abandoned AU2003261387A1 (en) 2003-02-24 2003-08-06 Methods of tangential flow filtration and an apparatus therefore

Country Status (8)

Country Link
US (2) US20040167320A1 (enExample)
EP (1) EP1601788A4 (enExample)
JP (1) JP2006515227A (enExample)
CN (1) CN1759189A (enExample)
AU (1) AU2003261387A1 (enExample)
CA (1) CA2516836A1 (enExample)
RU (1) RU2005129745A (enExample)
WO (1) WO2004076695A1 (enExample)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030005468A1 (en) * 1998-06-19 2003-01-02 Meade Harry M. Methods and vectors for improving nucleic acid expression
US20040226052A1 (en) * 2000-10-13 2004-11-11 Meade Harry M. Methods of producing a target molecule in a transgenic animal and purification of the target molecule
WO2005073732A2 (en) * 2004-01-23 2005-08-11 Amgen Inc. Lc/ms method of analyzing high molecular weight proteins
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
WO2005119126A1 (fr) * 2004-05-28 2005-12-15 Alstom Technology Ltd Dispositif a lit fluidise a agent comburant enrichi en oxygene
US20060051347A1 (en) * 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
AU2011203578B2 (en) * 2004-09-30 2012-10-11 Bayer Healthcare Llc Devices and methods for integrated continuous manufacturing of biological molecules
JP5579966B2 (ja) * 2004-09-30 2014-08-27 バイヤー ヘルスケア エルエルシー 生体分子の一貫連続製造のための装置及び方法
US20060130159A1 (en) * 2004-12-09 2006-06-15 Nick Masiello Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum
US7531632B2 (en) * 2006-02-16 2009-05-12 Gtc Biotherapeutics, Inc. Clarification of transgenic milk using depth filtration
DK2007506T3 (da) 2006-03-31 2014-06-16 Danisco Us Inc Tangentialstrømningsfiltreringsapparater, -systemer og -fremgangsmådertil separering af forbindelser
FR2901796A1 (fr) * 2006-05-31 2007-12-07 Lab Francais Du Fractionnement Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait
FR2901707B1 (fr) 2006-05-31 2017-09-29 Lab Francais Du Fractionnement Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis
US20080160134A1 (en) * 2006-12-27 2008-07-03 Jamie Allen Hestekin Method Of Producing Concentrated Liquid Dairy Products
FR2910786B1 (fr) 2006-12-29 2017-08-11 Laboratoire Francais Du Fractionnement Et Des Biotechnologies (Lfb) "procede d'extraction d'une proteine presente dans du lait"
GB0711327D0 (en) * 2007-06-12 2007-07-25 Hansa Medical Ab Diagnostic method
AU2008277886B8 (en) 2007-07-17 2013-08-01 F. Hoffmann-La Roche Ag Variable tangential flow filtration
JP5205470B2 (ja) * 2007-11-29 2013-06-05 エフ．ホフマン−ラ ロシュ アーゲー 免疫グロブリン凝集物
JP5717625B2 (ja) * 2008-05-14 2015-05-13 アグリカルチャー ヴィクトリア サービス ピーティーワイ エルティーディーＡｇｒｉｃｕｌｔｕｒｅ Ｖｉｃｔｏｒｉａ Ｓｅｒｖｉｃｅｓ Ｐｔｙ Ｌｔｄ アンギオゲニン濃縮ミルク分画
JP5762951B2 (ja) * 2008-05-15 2015-08-12 ダブリュ．・ヘルス・エル．ピー．Ｗ． Ｈｅａｌｔｈ Ｌ．Ｐ． 分泌性免疫グロブリンの豊富な乳画分の製造方法
US9055752B2 (en) 2008-11-06 2015-06-16 Intercontinental Great Brands Llc Shelf-stable concentrated dairy liquids and methods of forming thereof
CN102191226A (zh) * 2010-03-08 2011-09-21 北京清大天一科技有限公司 细胞培养混合物的分离纯化方法
UA112972C2 (uk) 2010-09-08 2016-11-25 Інтерконтінентал Грейт Брендс ЛЛС Рідкий молочний концентрат з високим вмістом сухих речовин
JP6189751B2 (ja) 2010-12-30 2017-08-30 ラボラトワール フランセ デュ フラクショヌマン エ デ ビオテクノロジーＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ ｅｔ ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ 病原体不活性化剤としてのグリコール
US8840790B2 (en) * 2011-04-27 2014-09-23 Fenwal, Inc. Systems and methods of controlling fouling during a filtration procedure
JP6363017B2 (ja) 2011-09-01 2018-07-25 中外製薬株式会社 限外ろ過によって高度に濃縮された抗体を含む組成物を調製するための方法
EP2885392A1 (en) * 2012-08-20 2015-06-24 Terumo BCT, Inc. Concentrating components of fluid circulated through a cell growth chamber
BR112015009553A2 (pt) * 2012-10-30 2017-10-03 Hoffmann La Roche Método para separar uma proteína de interesse de uma solução de cultura de células
US10478543B2 (en) 2013-01-11 2019-11-19 The Charles Stark Draper Laboratory, Inc. Systems and methods for increasing convective clearance of undesired particles in a microfluidic device
CN104968408B (zh) * 2013-02-05 2019-09-17 普凯尔德诊断技术有限公司 过滤装置以及使用该过滤装置的方法
JP2016508515A (ja) 2013-02-13 2016-03-22 ラボラトワール フランセ デュ フラクショヌマン エ デ ビオテクノロジーＬａｂｏｒａｔｏｉｒｅ Ｆｒａｎｃａｉｓ ｄｕ Ｆｒａｃｔｉｏｎｎｅｍｅｎｔ ｅｔ ｄｅｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ 高ガラクトシル化抗ＴＮＦ−α抗体およびその使用
US10034921B2 (en) 2013-02-13 2018-07-31 Laboratoire Français Du Fractionnement Et Des Biotechnologies Proteins with modified glycosylation and methods of production thereof
EA201591229A1 (ru) 2013-03-14 2016-01-29 Шир Хьюман Дженетик Терапис, Инк. Способы очистки матричной рнк
AU2014285971A1 (en) 2013-07-05 2016-02-04 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Affinity chromatography matrix
EP2907565A1 (de) * 2014-02-17 2015-08-19 Bayer Technology Services GmbH Dialyse-Einheit zum kontinuierlichen Puffer- bzw. Medienaustausch aus einer Proteinlösung
CN106457153B (zh) * 2014-03-07 2019-03-29 新加坡科技研究局 用于分级分离生物制品的装置和方法
CN112588116A (zh) 2014-05-13 2021-04-02 美国安进公司 用于过滤器和过滤过程的过程控制系统和方法
ES2926985T3 (es) 2014-05-15 2022-10-31 Insmed Inc Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas
EP3148713B1 (en) * 2014-05-27 2025-02-12 Artificial Cell Technologies, Inc. Automated layer by layer construction of multilayer coated cores by tff
WO2015195452A2 (en) * 2014-06-16 2015-12-23 Emd Millipore Corporation Single-pass filtration systems and processes
EP4144434B1 (en) * 2014-06-16 2024-04-17 EMD Millipore Corporation Single-pass filtration systems and processes
EP2957335B1 (en) * 2014-06-16 2020-05-27 EMD Millipore Corporation Single-pass filtration systems and processes
WO2015195453A2 (en) 2014-06-16 2015-12-23 Emd Millipore Corporation Methods for increasing the capacity of flow-through processes
KR101938948B1 (ko) 2014-06-25 2019-01-15 이엠디 밀리포어 코포레이션 밀집한 나권형 필터 엘리먼트, 모듈 및 시스템
JP6615890B2 (ja) * 2014-08-21 2019-12-04 ザ チャールズ スターク ドレイパー ラボラトリー， インク． マイクロ流体装置中の望まれない粒子の対流クリアランスを増すためのシステムおよび方法
WO2016033553A1 (en) 2014-08-29 2016-03-03 Emd Millipore Corporation Processes for filtering liquids using single pass tangential flow filtration systems and tangential flow filtration systems with recirculation of retentate
WO2016033546A1 (en) 2014-08-29 2016-03-03 Emd Millipore Corporation Single pass tangential flow filtration systems and tangential flow filtration systems with recirculation of retentate
CN106188300A (zh) * 2015-05-07 2016-12-07 温州市人民医院 一种保持胱抑素c抗体-胶乳共价偶联复合物活性的快速纯化方法
DK4108769T3 (da) 2015-05-29 2023-10-09 Curevac Mfg Gmbh Fremgangsmåde til fremstilling og oprensning af rna, omfattende mindst et trin til tangential-flow-filtrering
FR3038517B1 (fr) 2015-07-06 2020-02-28 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Utilisation de fragments fc modifies en immunotherapie
CN107320765A (zh) * 2016-04-29 2017-11-07 深圳兰度生物材料有限公司 一种重组纤维结构胶原蛋白海绵的制备方法
US12226737B2 (en) 2016-06-09 2025-02-18 Emd Millipore Corporation Radial-path filter elements, systems and methods of using same
BR102017001309A2 (pt) * 2017-01-23 2018-08-14 Fundação Oswaldo Cruz vacina recombinante para helmintos em pichia pastoris, e, processos de produção e purificação de proteína como vacina para helmintos
WO2019084178A1 (en) * 2017-10-24 2019-05-02 Cerahelix, Inc. SYSTEMS AND METHODS FOR MULTI-STAGE FLUID SEPARATION
CN107907643A (zh) * 2017-11-10 2018-04-13 福建省水产研究所 一种测定天然海水中溶解相、纳米相和真溶液相中有机碳和无机氮含量的方法
CN110241012B (zh) * 2018-03-09 2022-11-01 嘉和生物药业有限公司 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用
EP3773505A4 (en) 2018-03-30 2021-12-22 Insmed Incorporated PROCESS FOR THE CONTINUOUS MANUFACTURING OF LIPOSOMAL MEDICINAL PRODUCTS
EP3794013B1 (en) 2018-05-17 2024-02-21 CSL Behring AG Method and system of protein extraction
CN113518655B (zh) * 2019-01-30 2023-02-17 瑞普利金公司 使用径迹蚀刻膜过滤生物流体的方法
CN110607272B (zh) * 2019-09-23 2022-11-01 山东甲骨文生物科技有限公司 一种哺乳动物细胞培养液的添加剂及细胞培养液
US12285723B2 (en) * 2019-10-01 2025-04-29 Tetra Laval Holdings & Finance S.A. Method for filtering a dairy product
JP2023502412A (ja) * 2019-11-20 2023-01-24 ツェー・エス・エル・ベーリング・アクチエンゲゼルシャフト 沈殿物からタンパク質を抽出する方法および不純物を沈殿させる方法
CN111018968B (zh) * 2019-12-16 2021-07-27 兴盟生物医药(苏州)有限公司 一种通过超滤浓缩制备高浓度抗体制剂的方法
KR20230024891A (ko) * 2020-06-11 2023-02-21 2세븐티 바이오, 인코포레이티드 바이러스 벡터 제조 방법
CN113713621B (zh) * 2021-08-26 2022-08-02 杭州纽创生物检测有限公司 一种应用于病毒的sptff装置、灌注系统及病毒料液过滤方法
CN116328553A (zh) * 2022-11-16 2023-06-27 安徽百奥秘科生物医药研究院有限公司 一种过滤膜及一步过滤快速提取核酸装置及提取核酸方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888115A (en) * 1983-12-29 1989-12-19 Cuno, Incorporated Cross-flow filtration
US4874516A (en) * 1984-12-29 1989-10-17 Ngk Insulators, Ltd. A ceramic filter for semi-ultrafiltration
US5948441A (en) * 1988-03-07 1999-09-07 The Liposome Company, Inc. Method for size separation of particles
US5256294A (en) * 1990-09-17 1993-10-26 Genentech, Inc. Tangential flow filtration process and apparatus
SE470375B (sv) * 1992-05-07 1994-02-07 Alfa Laval Food Eng Ab Sätt att erhålla högvärdiga proteinprodukter ur vassle
US5356651A (en) * 1992-12-30 1994-10-18 Pall Corporation Manufacturing method for producing sterile milk using dynamic microfiltration
US5518624A (en) * 1994-05-06 1996-05-21 Illinois Water Treatment, Inc. Ultra pure water filtration
US5585466A (en) * 1994-12-06 1996-12-17 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Crystals of serum albumin for use in genetic engineering and rational drug design
US6268487B1 (en) * 1996-05-13 2001-07-31 Genzyme Transgenics Corporation Purification of biologically active peptides from milk
GB9807464D0 (en) * 1998-04-07 1998-06-10 Pharming Bv Purification of human acid µ-glucosidase
AU756832B2 (en) * 1999-02-22 2003-01-23 Ncsrt, Inc. Purification of biological substances
US6984378B1 (en) * 1999-02-26 2006-01-10 Pfizer, Inc. Method for the purification, recovery, and sporulation of cysts and oocysts

Also Published As

Publication number Publication date
WO2004076695A1 (en) 2004-09-10
EP1601788A1 (en) 2005-12-07
CN1759189A (zh) 2006-04-12
JP2006515227A (ja) 2006-05-25
RU2005129745A (ru) 2006-03-20
US20040167320A1 (en) 2004-08-26
CA2516836A1 (en) 2004-09-10
EP1601788A4 (en) 2006-11-15
US20050260672A1 (en) 2005-11-24

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