CN1731997A - 使用包含选择性细胞因子抑制药物的组合物治疗和控制黄斑变性的方法 - Google Patents
使用包含选择性细胞因子抑制药物的组合物治疗和控制黄斑变性的方法 Download PDFInfo
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- CN1731997A CN1731997A CNA2003801080906A CN200380108090A CN1731997A CN 1731997 A CN1731997 A CN 1731997A CN A2003801080906 A CNA2003801080906 A CN A2003801080906A CN 200380108090 A CN200380108090 A CN 200380108090A CN 1731997 A CN1731997 A CN 1731997A
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
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- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
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- Neurosurgery (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42290002P | 2002-10-31 | 2002-10-31 | |
| US60/422,900 | 2002-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1731997A true CN1731997A (zh) | 2006-02-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CNA2003801080906A Pending CN1731997A (zh) | 2002-10-31 | 2003-10-31 | 使用包含选择性细胞因子抑制药物的组合物治疗和控制黄斑变性的方法 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1567148A4 (de) |
| JP (1) | JP2006509743A (de) |
| KR (1) | KR20050062649A (de) |
| CN (1) | CN1731997A (de) |
| AU (1) | AU2003285107B2 (de) |
| BR (1) | BR0315889A (de) |
| CA (1) | CA2504263A1 (de) |
| MX (1) | MXPA05004486A (de) |
| NZ (1) | NZ540185A (de) |
| TW (1) | TW200418455A (de) |
| WO (1) | WO2004041181A2 (de) |
| ZA (1) | ZA200503468B (de) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103402980A (zh) * | 2011-01-10 | 2013-11-20 | 细胞基因公司 | 作为pde 4 和/或细胞因子抑制剂的苯乙基砜异吲哚啉衍生物 |
| WO2020113373A1 (en) * | 2018-12-03 | 2020-06-11 | Zhuhai Qiwei Bio-Technology Ltd. | Method of treating age-related macular degeneration |
| CN113226020A (zh) * | 2018-11-14 | 2021-08-06 | 珠海岐微生物科技有限公司 | 用于眼内疾病或病症的动物模型、筛选方法和治疗方法 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040091455A1 (en) * | 2002-10-31 | 2004-05-13 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration |
| US7776907B2 (en) * | 2002-10-31 | 2010-08-17 | Celgene Corporation | Methods for the treatment and management of macular degeneration using cyclopropyl-N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindoline-4-yl}carboxamide |
| KR101908330B1 (ko) | 2017-02-17 | 2018-10-16 | 인제대학교 산학협력단 | 신규 항-vegf 항체 및 이를 유효성분으로 포함하는 나이관련 황반변성 예방 또는 치료용 조성물 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US577589A (en) * | 1897-02-23 | Valve for explosive-engines | ||
| US5698579A (en) * | 1993-07-02 | 1997-12-16 | Celgene Corporation | Cyclic amides |
| US5605914A (en) * | 1993-07-02 | 1997-02-25 | Celgene Corporation | Imides |
| WO1995003807A1 (en) * | 1993-07-27 | 1995-02-09 | The University Of Sydney | Treatment of age-related macular degeneration |
| EP1035848B1 (de) * | 1997-07-31 | 2003-04-23 | Celgene Corporation | Susstituierte alkanhydroxamisaeure und verfahren zur verminderung des tnf-alphaspiegels |
| CA2331461C (en) * | 1998-05-11 | 2008-10-07 | Entremed, Inc. | Analogs of 2-phthalimidinoglutaric acid and their use as inhibitors of angiogenesis |
| US6020358A (en) * | 1998-10-30 | 2000-02-01 | Celgene Corporation | Substituted phenethylsulfones and method of reducing TNFα levels |
| JP2000159761A (ja) * | 1998-11-30 | 2000-06-13 | Yoshio Takeuchi | フルオロサリドマイド |
| US6667316B1 (en) * | 1999-11-12 | 2003-12-23 | Celgene Corporation | Pharmaceutically active isoindoline derivatives |
| CA2482022A1 (en) * | 2002-04-19 | 2003-10-30 | Smithkline Beecham Corporation | Novel compounds |
| IL165258A0 (en) * | 2002-05-17 | 2005-12-18 | Celgene Corp | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases |
| US7842691B2 (en) * | 2002-10-15 | 2010-11-30 | Celgene Corporation | Method for the treatment of myelodysplastic syndromes using cyclopropanecarboxylic acid {2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-OXO-2,3-dihydro-1 H-isoindol-4-yl}-amide |
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2003
- 2003-10-31 ZA ZA200503468A patent/ZA200503468B/en unknown
- 2003-10-31 NZ NZ540185A patent/NZ540185A/en not_active IP Right Cessation
- 2003-10-31 CA CA002504263A patent/CA2504263A1/en not_active Abandoned
- 2003-10-31 MX MXPA05004486A patent/MXPA05004486A/es active IP Right Grant
- 2003-10-31 WO PCT/US2003/034535 patent/WO2004041181A2/en active Application Filing
- 2003-10-31 TW TW092130486A patent/TW200418455A/zh unknown
- 2003-10-31 EP EP03779423A patent/EP1567148A4/de not_active Withdrawn
- 2003-10-31 JP JP2004550274A patent/JP2006509743A/ja active Pending
- 2003-10-31 CN CNA2003801080906A patent/CN1731997A/zh active Pending
- 2003-10-31 AU AU2003285107A patent/AU2003285107B2/en not_active Ceased
- 2003-10-31 KR KR1020057007608A patent/KR20050062649A/ko not_active Application Discontinuation
- 2003-10-31 BR BR0315889-6A patent/BR0315889A/pt not_active IP Right Cessation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103402980A (zh) * | 2011-01-10 | 2013-11-20 | 细胞基因公司 | 作为pde 4 和/或细胞因子抑制剂的苯乙基砜异吲哚啉衍生物 |
| CN103402980B (zh) * | 2011-01-10 | 2016-06-29 | 细胞基因公司 | 作为pde4和/或细胞因子抑制剂的苯乙基砜异吲哚啉衍生物 |
| CN113226020A (zh) * | 2018-11-14 | 2021-08-06 | 珠海岐微生物科技有限公司 | 用于眼内疾病或病症的动物模型、筛选方法和治疗方法 |
| WO2020113373A1 (en) * | 2018-12-03 | 2020-06-11 | Zhuhai Qiwei Bio-Technology Ltd. | Method of treating age-related macular degeneration |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200503468B (en) | 2006-10-25 |
| JP2006509743A (ja) | 2006-03-23 |
| WO2004041181A2 (en) | 2004-05-21 |
| MXPA05004486A (es) | 2005-07-26 |
| CA2504263A1 (en) | 2004-05-21 |
| NZ540185A (en) | 2008-01-31 |
| EP1567148A4 (de) | 2010-09-15 |
| TW200418455A (en) | 2004-10-01 |
| EP1567148A2 (de) | 2005-08-31 |
| KR20050062649A (ko) | 2005-06-23 |
| AU2003285107A1 (en) | 2004-06-07 |
| BR0315889A (pt) | 2005-10-04 |
| AU2003285107B2 (en) | 2008-01-10 |
| WO2004041181A3 (en) | 2005-02-17 |
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