CN1690203A - β-淀粉样肽结合蛋白及其编码聚核苷酸 - Google Patents

β-淀粉样肽结合蛋白及其编码聚核苷酸 Download PDF

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Publication number
CN1690203A
CN1690203A CNA200510052975XA CN200510052975A CN1690203A CN 1690203 A CN1690203 A CN 1690203A CN A200510052975X A CNA200510052975X A CN A200510052975XA CN 200510052975 A CN200510052975 A CN 200510052975A CN 1690203 A CN1690203 A CN 1690203A
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China
Prior art keywords
polynucleotide
protein
bbp
amyloid peptide
sequence
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Pending
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CNA200510052975XA
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English (en)
Chinese (zh)
Inventor
B·A·奥藏伯格
E·M·卡科斯基
J·S·雅各布森
J·A·巴德
S·G·沃克
H·索菲娅
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Wyeth LLC
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Wyeth LLC
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Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of CN1690203A publication Critical patent/CN1690203A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNA200510052975XA 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸 Pending CN1690203A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6458397P 1997-04-16 1997-04-16
US60/064,583 1997-04-16

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB988043173A Division CN1196785C (zh) 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸

Publications (1)

Publication Number Publication Date
CN1690203A true CN1690203A (zh) 2005-11-02

Family

ID=22056941

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA200510052975XA Pending CN1690203A (zh) 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸
CNB988043173A Expired - Fee Related CN1196785C (zh) 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB988043173A Expired - Fee Related CN1196785C (zh) 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸

Country Status (18)

Country Link
EP (1) EP0975753A2 (enrdf_load_stackoverflow)
JP (3) JP2001523093A (enrdf_load_stackoverflow)
KR (1) KR20010006393A (enrdf_load_stackoverflow)
CN (2) CN1690203A (enrdf_load_stackoverflow)
AU (1) AU740445B2 (enrdf_load_stackoverflow)
BR (1) BR9808562A (enrdf_load_stackoverflow)
CA (1) CA2286484A1 (enrdf_load_stackoverflow)
EA (1) EA004256B1 (enrdf_load_stackoverflow)
EE (1) EE9900482A (enrdf_load_stackoverflow)
GE (1) GEP20043386B (enrdf_load_stackoverflow)
HU (1) HUP0003116A3 (enrdf_load_stackoverflow)
ID (1) ID24914A (enrdf_load_stackoverflow)
IL (3) IL132236A0 (enrdf_load_stackoverflow)
NO (1) NO995062L (enrdf_load_stackoverflow)
NZ (1) NZ500216A (enrdf_load_stackoverflow)
SK (1) SK143299A3 (enrdf_load_stackoverflow)
UA (1) UA72875C2 (enrdf_load_stackoverflow)
WO (1) WO1998046636A2 (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102060912A (zh) * 2010-11-22 2011-05-18 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
US6787319B2 (en) * 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
JP2002527064A (ja) * 1998-10-13 2002-08-27 アメリカン・ホーム・プロダクツ・コーポレイション 6−蛋白結合受容体様蛋白、それらによりコードされるポリヌクレオチド、ならびにそれらの使用方法
US6455082B1 (en) * 1999-04-26 2002-09-24 Nestec S.A. Shelf-stable calcium fortified milk and dairy products
CA2387646A1 (en) * 1999-10-21 2001-04-26 Kalobios, Inc. A general method for optimizing the expression of heterologous proteins
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
WO2012020124A1 (en) 2010-08-12 2012-02-16 Ac Immune S.A. Vaccine engineering
CN103189050B (zh) 2010-10-26 2017-09-29 Ac免疫有限公司 包含通过疏水部分修饰的肽的基于脂质体的构建体
CN111320678B (zh) * 2020-03-09 2023-06-09 安亭生物有限责任公司 抗菌肽突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611122B2 (en) * 1986-11-17 1991-06-06 Scios Nova Inc. Recombinant alzheimer's amyloid protein
IL115743A0 (en) * 1994-10-28 1996-01-19 American Nat Red Cross A mammal with cells containing a transgene and its production
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102060912A (zh) * 2010-11-22 2011-05-18 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用
CN102060912B (zh) * 2010-11-22 2012-11-14 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用

Also Published As

Publication number Publication date
JP2008104465A (ja) 2008-05-08
EP0975753A2 (en) 2000-02-02
KR20010006393A (ko) 2001-01-26
WO1998046636A2 (en) 1998-10-22
AU740445B2 (en) 2001-11-01
UA72875C2 (uk) 2005-05-16
HUP0003116A3 (en) 2003-03-28
JP2001523093A (ja) 2001-11-20
JP2008253275A (ja) 2008-10-23
GEP20043386B (en) 2004-02-10
IL179047A0 (en) 2007-03-08
NZ500216A (en) 2001-06-29
NO995062L (no) 1999-12-14
AU7115698A (en) 1998-11-11
EE9900482A (enrdf_load_stackoverflow) 2000-06-15
CN1196785C (zh) 2005-04-13
SK143299A3 (en) 2000-09-12
ID24914A (id) 2000-08-31
CA2286484A1 (en) 1998-10-22
IL132236A0 (en) 2001-03-19
HUP0003116A2 (hu) 2001-01-29
CN1268973A (zh) 2000-10-04
IL132236A (en) 2007-03-08
BR9808562A (pt) 2000-05-23
WO1998046636A3 (en) 1999-01-28
EA004256B1 (ru) 2004-02-26
NO995062D0 (no) 1999-10-15
EA199900941A1 (ru) 2000-06-26

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Open date: 20051102