CN1516695A - 用作抗病毒剂的芳基磺酰胺类化合物 - Google Patents

用作抗病毒剂的芳基磺酰胺类化合物 Download PDF

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Publication number
CN1516695A
CN1516695A CNA028121589A CN02812158A CN1516695A CN 1516695 A CN1516695 A CN 1516695A CN A028121589 A CNA028121589 A CN A028121589A CN 02812158 A CN02812158 A CN 02812158A CN 1516695 A CN1516695 A CN 1516695A
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CN
China
Prior art keywords
hydroxyl
group
alkyl
amino
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028121589A
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English (en)
Chinese (zh)
Inventor
T
T·旺伯格
W·本德
����ϲ��
P·埃肯伯格
S·伦伯格
�ָ���
K·亨林格
J·科德尼奇
A·科尔恩
�´���
S·拉德达茨
J·里施莱格
G·施米德特
H·滋梅曼恩
F·朱姆佩
M·拉德特科
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10148598A external-priority patent/DE10148598A1/de
Application filed by Bayer AG filed Critical Bayer AG
Publication of CN1516695A publication Critical patent/CN1516695A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CNA028121589A 2001-04-19 2002-04-08 用作抗病毒剂的芳基磺酰胺类化合物 Pending CN1516695A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19
DE10119137.5 2001-04-19
DE10148598.0 2001-10-02
DE10148598A DE10148598A1 (de) 2001-04-19 2001-10-02 Neue Arylsulfonamide als antivirale Mittel

Publications (1)

Publication Number Publication Date
CN1516695A true CN1516695A (zh) 2004-07-28

Family

ID=26009118

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028121589A Pending CN1516695A (zh) 2001-04-19 2002-04-08 用作抗病毒剂的芳基磺酰胺类化合物

Country Status (20)

Country Link
US (1) US7115612B2 (https=)
EP (1) EP1383749B1 (https=)
JP (1) JP4480941B2 (https=)
CN (1) CN1516695A (https=)
AT (1) ATE308529T1 (https=)
BG (1) BG108272A (https=)
BR (1) BR0209054A (https=)
CA (1) CA2444123C (https=)
DE (1) DE50204780D1 (https=)
EE (1) EE200300515A (https=)
ES (1) ES2252455T3 (https=)
HU (1) HUP0303813A3 (https=)
IL (1) IL158324A0 (https=)
MX (1) MXPA03009548A (https=)
NO (1) NO20034667L (https=)
PL (1) PL363990A1 (https=)
RU (1) RU2003133750A (https=)
SK (1) SK12662003A3 (https=)
UY (1) UY27263A1 (https=)
WO (1) WO2002085869A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101389607B (zh) * 2006-03-03 2011-09-07 艾库里斯有限及两合公司 作为抗病毒剂的取代的芳基磺酰胺

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20050168A2 (en) * 2002-08-23 2005-10-31 Rigel Pharmaceuticals Pyridyl substituted heterocycles useful for treating or preventing hcv infection
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
EP4101846B1 (en) 2003-04-11 2023-08-02 PTC Therapeutics, Inc. 1,2,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease
EP2387995A1 (en) 2006-03-30 2011-11-23 PTC Therapeutics, Inc. Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
US20100240657A1 (en) * 2007-07-02 2010-09-23 Boehringer Ingelheim International Gmbh Chemical compounds
EP2177521A1 (en) * 2008-10-14 2010-04-21 Almirall, S.A. New 2-Amidothiadiazole Derivatives
EP2202232A1 (en) * 2008-12-26 2010-06-30 Laboratorios Almirall, S.A. 1,2,4-oxadiazole derivatives and their therapeutic use
AR083431A1 (es) * 2010-06-28 2013-02-27 Bayer Cropscience Ag Compuestos heterociclicos como pesticidas
JP2013531687A (ja) 2010-07-16 2013-08-08 パーデュー、ファーマ、リミテッド、パートナーシップ ナトリウムチャネル遮断剤としてのピリジン化合物
WO2013136170A1 (en) 2012-03-16 2013-09-19 Purdue Pharma L.P. Substituted pyridines as sodium channel blockers
US9284310B2 (en) 2012-11-03 2016-03-15 Boehringer Ingelheim International Gmbh Inhibitors of cytomegalovirus
JP6372666B2 (ja) 2012-11-03 2018-08-15 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング サイトメガロウイルスの阻害剤
WO2014096941A1 (en) 2012-12-20 2014-06-26 Purdue Pharma L.P. Cyclic sulfonamides as sodium channel blockers
TWI695717B (zh) 2014-03-06 2020-06-11 美商 Ptc 治療公司 １,２,４-二唑苯甲酸之鹽及醫藥組合物
US10730866B2 (en) 2014-04-07 2020-08-04 Purdue Pharma L.P. Indole derivatives and use thereof
JP6749344B2 (ja) * 2015-02-13 2020-09-02 アジエンダ・オスペダリエラ・ウニベルシタリア・セネーゼ 治療剤としてのヒトヘリカーゼｄｄｘ３阻害剤
CN108348527A (zh) 2015-10-30 2018-07-31 Ptc医疗公司 用于治疗癫痫的方法
BR112019020252A2 (pt) * 2017-03-31 2020-04-22 Perenna Pharmaceuticals Inc compostos úteis como inibidores de alcat 1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19802437A1 (de) 1998-01-23 1999-07-29 Bayer Ag Verwendung von substituierten Sulfonamiden als anitvirale Mittel und neue Stoffe
CN1347411A (zh) * 1999-04-19 2002-05-01 盐野义制药株式会社 含有噁二唑环的磺酰胺衍生物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101389607B (zh) * 2006-03-03 2011-09-07 艾库里斯有限及两合公司 作为抗病毒剂的取代的芳基磺酰胺

Also Published As

Publication number Publication date
CA2444123A1 (en) 2002-10-31
EE200300515A (et) 2004-02-16
US7115612B2 (en) 2006-10-03
PL363990A1 (en) 2004-11-29
EP1383749A1 (de) 2004-01-28
BG108272A (bg) 2004-10-29
RU2003133750A (ru) 2005-05-10
WO2002085869A1 (de) 2002-10-31
NO20034667D0 (no) 2003-10-17
CA2444123C (en) 2010-09-21
HUP0303813A2 (hu) 2004-03-29
MXPA03009548A (es) 2004-05-24
UY27263A1 (es) 2002-11-29
BR0209054A (pt) 2004-04-20
US20040176374A1 (en) 2004-09-09
EP1383749B1 (de) 2005-11-02
JP4480941B2 (ja) 2010-06-16
ATE308529T1 (de) 2005-11-15
JP2004531536A (ja) 2004-10-14
DE50204780D1 (de) 2005-12-08
IL158324A0 (en) 2004-05-12
ES2252455T3 (es) 2006-05-16
NO20034667L (no) 2003-12-12
HUP0303813A3 (en) 2005-05-30
SK12662003A3 (sk) 2004-04-06

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