BR0209054A - Arilsulfonamidas como agentes antivirais - Google Patents

Arilsulfonamidas como agentes antivirais

Info

Publication number
BR0209054A
BR0209054A BR0209054-6A BR0209054A BR0209054A BR 0209054 A BR0209054 A BR 0209054A BR 0209054 A BR0209054 A BR 0209054A BR 0209054 A BR0209054 A BR 0209054A
Authority
BR
Brazil
Prior art keywords
arylsulfonamides
antiviral agents
well
arylulphonamides
substituents
Prior art date
Application number
BR0209054-6A
Other languages
English (en)
Inventor
Tobias Wunberg
Wolfgang Bender
Peter Eckenberg
Sabine Hallenberger
Kerstin Henninger
Joerg Keldenich
Armin Kern
Siegfried Raddatz
Juergen Reefschlaeger
Gunter Schmidt
Holger Zimmermann
Franz Zumpe
Martin Radtke
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10148598A external-priority patent/DE10148598A1/de
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BR0209054A publication Critical patent/BR0209054A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"ARILSULFONAMIDAS COMO AGENTES ANTIVIRAIS". A presente invenção refere-se a novas sulfonamidas da fórmula geral (I), na qual os substituintes R^ 1^, R^ 2^, R^ 3^, R^ 4^ bem como A e X têm os significados indicados, bem como processos para a sua preparação e sua aplicação como composições antivirais, especialmente contra citomegalovírus.
BR0209054-6A 2001-04-19 2002-04-08 Arilsulfonamidas como agentes antivirais BR0209054A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19
DE10148598A DE10148598A1 (de) 2001-04-19 2001-10-02 Neue Arylsulfonamide als antivirale Mittel
PCT/EP2002/003858 WO2002085869A1 (de) 2001-04-19 2002-04-08 Arylsulfonamide als antivirale mittel

Publications (1)

Publication Number Publication Date
BR0209054A true BR0209054A (pt) 2004-04-20

Family

ID=26009118

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209054-6A BR0209054A (pt) 2001-04-19 2002-04-08 Arilsulfonamidas como agentes antivirais

Country Status (20)

Country Link
US (1) US7115612B2 (pt)
EP (1) EP1383749B1 (pt)
JP (1) JP4480941B2 (pt)
CN (1) CN1516695A (pt)
AT (1) ATE308529T1 (pt)
BG (1) BG108272A (pt)
BR (1) BR0209054A (pt)
CA (1) CA2444123C (pt)
DE (1) DE50204780D1 (pt)
EE (1) EE200300515A (pt)
ES (1) ES2252455T3 (pt)
HU (1) HUP0303813A3 (pt)
IL (1) IL158324A0 (pt)
MX (1) MXPA03009548A (pt)
NO (1) NO20034667L (pt)
PL (1) PL363990A1 (pt)
RU (1) RU2003133750A (pt)
SK (1) SK12662003A3 (pt)
UY (1) UY27263A1 (pt)
WO (1) WO2002085869A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2494164A1 (en) * 2002-08-23 2004-03-04 Rigel Pharmaceuticals, Inc. Pyridyl substituted heterocycles useful for treating or preventing hcv infection
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
UA84420C2 (ru) 2003-04-11 2008-10-27 ПиТиСи ТЕРАПЬЮТИКС, ИНК. СОЕДИНЕНИЯ 1,2,4-ОКСАДИАЗОЛБЕНЗОЙНОЙ КИСЛОТЫ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ (ВАРИАНТЫ) И ПРИМЕНЕНИЕ СОЕДИНЕНИЙ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, СВЯЗАННОГО С ПРЕЖДЕВРЕМЕННОЙ ТЕРМИНАЦИЕЙ ТРАНСЛЯЦИИ ИЛИ НОНСЕНС-ОБУСЛОВЛЕННЫМ УМЕНЬШЕНИЕМ мРНК
DE102006009928A1 (de) * 2006-03-03 2007-09-06 Aicuris Gmbh & Co. Kg Substituierte Arylsulfonamide
JP5367563B2 (ja) 2006-03-30 2013-12-11 ピーティーシー セラピューティクス，インコーポレーテッド ナンセンス突然変異を有するｄｎａからの機能的タンパク質の産生のための方法及びそれと関連した障害の治療
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
CA2692379A1 (en) * 2007-07-02 2009-01-08 Boehringer Ingelheim International Gmbh Antiproliferative compounds based on 5-membered heterocycles
EP2177521A1 (en) * 2008-10-14 2010-04-21 Almirall, S.A. New 2-Amidothiadiazole Derivatives
EP2202232A1 (en) * 2008-12-26 2010-06-30 Laboratorios Almirall, S.A. 1,2,4-oxadiazole derivatives and their therapeutic use
WO2012000896A2 (de) * 2010-06-28 2012-01-05 Bayer Cropscience Ag Heterocyclische verbindungen als schädlingsbekämpfungsmittel
US9120752B2 (en) 2010-07-16 2015-09-01 Purdue Pharma, L.P. Pyridine compounds as sodium channel blockers
AU2013203824A1 (en) 2012-03-16 2013-10-03 Purdue Pharma L.P. Substituted pyridines and pryimidines as sodium channel blockers
WO2014070979A1 (en) * 2012-11-03 2014-05-08 Boehringer Ingelheim International Gmbh Inhibitors of cytomegalovirus
WO2014070978A1 (en) * 2012-11-03 2014-05-08 Boehringer Ingelheim International Gmbh Inhibitors of cytomegalovirus
US9714252B2 (en) 2012-12-20 2017-07-25 Purdue Pharma L.P. Cyclic sulfonamides as sodium channel blockers
CA3174516A1 (en) 2014-03-06 2015-09-11 Ptc Therapeutics, Inc. Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid
US10730866B2 (en) 2014-04-07 2020-08-04 Purdue Pharma L.P. Indole derivatives and use thereof
EP3256461B1 (en) * 2015-02-13 2023-09-13 Azienda Ospedaliera Universitaria Senese Urea and sulfonamide derivatives as human helicase ddx3 inhibitors useful in the treatment of viral diseases
WO2017075312A1 (en) 2015-10-30 2017-05-04 Ptc Therapeutics, Inc. Methods for treating epilepsy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19802437A1 (de) * 1998-01-23 1999-07-29 Bayer Ag Verwendung von substituierten Sulfonamiden als anitvirale Mittel und neue Stoffe
PL351374A1 (en) * 1999-04-19 2003-04-07 Shionogi & Co Sulfonamide derivatives having oxadiazole rings

Also Published As

Publication number Publication date
NO20034667D0 (no) 2003-10-17
ES2252455T3 (es) 2006-05-16
JP4480941B2 (ja) 2010-06-16
IL158324A0 (en) 2004-05-12
US20040176374A1 (en) 2004-09-09
EE200300515A (et) 2004-02-16
CN1516695A (zh) 2004-07-28
UY27263A1 (es) 2002-11-29
CA2444123A1 (en) 2002-10-31
EP1383749A1 (de) 2004-01-28
PL363990A1 (en) 2004-11-29
HUP0303813A2 (hu) 2004-03-29
HUP0303813A3 (en) 2005-05-30
SK12662003A3 (sk) 2004-04-06
RU2003133750A (ru) 2005-05-10
NO20034667L (no) 2003-12-12
CA2444123C (en) 2010-09-21
MXPA03009548A (es) 2004-05-24
JP2004531536A (ja) 2004-10-14
US7115612B2 (en) 2006-10-03
BG108272A (bg) 2004-10-29
ATE308529T1 (de) 2005-11-15
EP1383749B1 (de) 2005-11-02
WO2002085869A1 (de) 2002-10-31
DE50204780D1 (de) 2005-12-08

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009.