EA200600212A1 - 2-замещенные пиримидины - Google Patents

2-замещенные пиримидины

Info

Publication number
EA200600212A1
EA200600212A1 EA200600212A EA200600212A EA200600212A1 EA 200600212 A1 EA200600212 A1 EA 200600212A1 EA 200600212 A EA200600212 A EA 200600212A EA 200600212 A EA200600212 A EA 200600212A EA 200600212 A1 EA200600212 A1 EA 200600212A1
Authority
EA
Eurasian Patent Office
Prior art keywords
substituted pyrimidines
description
meanings indicated
pesticides
substituents
Prior art date
Application number
EA200600212A
Other languages
English (en)
Other versions
EA010566B1 (ru
Inventor
Аня Швёглер
Маркус Гевер
Бернд МЮЛЛЕР
Томас Гроте
Вассилиос Грамменос
Хорди Тормо И Бласко
Андреас Гипзер
Йоахим Райнхаймер
Карстен Блеттнер
Петер Шэфер
Франк Шивекк
Оливер Вагнер
Райнхард Штирль
Ульрих Шёфль
Зигфрид Штратманн
Мария Шерер
Original Assignee
Басф Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Басф Акциенгезельшафт filed Critical Басф Акциенгезельшафт
Publication of EA200600212A1 publication Critical patent/EA200600212A1/ru
Publication of EA010566B1 publication Critical patent/EA010566B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение относится к 2-замещенным пиримидинам формулы Iв которой индекс n и заместители от Rдо R, а также L имеют указанные в описании значения и Rсоответствует формуламв которых R, X и Rимеют указанные в описании значения; а также к способу их получения, к содержащим их пестицидным средствам и их применению в качестве пестицидов.
EA200600212A 2003-07-24 2004-07-15 2-замещенные пиримидины, способ их получения, пестицидное средство и способ борьбы с фитопатогенными грибами EA010566B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10333857 2003-07-24
DE10357714 2003-12-09
PCT/EP2004/007877 WO2005012261A1 (de) 2003-07-24 2004-07-15 2-substituierte pyrimidine

Publications (2)

Publication Number Publication Date
EA200600212A1 true EA200600212A1 (ru) 2006-08-25
EA010566B1 EA010566B1 (ru) 2008-10-30

Family

ID=34117367

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200600212A EA010566B1 (ru) 2003-07-24 2004-07-15 2-замещенные пиримидины, способ их получения, пестицидное средство и способ борьбы с фитопатогенными грибами

Country Status (30)

Country Link
US (1) US7375108B2 (ru)
EP (1) EP1651618B1 (ru)
JP (1) JP2006528603A (ru)
KR (1) KR20060052857A (ru)
AP (1) AP2157A (ru)
AR (1) AR045100A1 (ru)
AT (1) ATE350370T1 (ru)
AU (1) AU2004261373B8 (ru)
BR (1) BRPI0412891A (ru)
CA (1) CA2532718A1 (ru)
CO (1) CO5660292A2 (ru)
CR (1) CR8184A (ru)
CY (1) CY1106391T1 (ru)
DE (1) DE502004002570D1 (ru)
DK (1) DK1651618T3 (ru)
EA (1) EA010566B1 (ru)
EC (1) ECSP066278A (ru)
ES (1) ES2279395T3 (ru)
HR (1) HRP20070057T3 (ru)
IL (1) IL172848A0 (ru)
MA (1) MA27949A1 (ru)
MX (1) MXPA06000038A (ru)
NZ (1) NZ545103A (ru)
PE (1) PE20050882A1 (ru)
PL (1) PL1651618T3 (ru)
PT (1) PT1651618E (ru)
SI (1) SI1651618T1 (ru)
TW (1) TW200516075A (ru)
UY (1) UY28436A1 (ru)
WO (1) WO2005012261A1 (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008505957A (ja) * 2004-07-14 2008-02-28 ビーエーエスエフ　アクチェンゲゼルシャフト ２−置換ピリミジン、その調製方法および有害菌類を防除するためのその使用
CL2007002231A1 (es) * 2006-08-02 2008-04-11 Basf Ag Uso de compuestos derivados de 5-(het) arilpirimidina para combatir hongos daninos; compuestos derivados de 5-(het) arilpirimidina; agente fungicida; y agente farmaceutico.
CA2818125A1 (en) * 2010-11-16 2012-05-24 Acetylon Pharmaceuticals, Inc. Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof
JP6626437B2 (ja) 2013-10-08 2019-12-25 アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． ヒストンデアセチラーゼ阻害剤とＨｅｒ２阻害剤またはＰＩ３Ｋ阻害剤のいずれかの組み合わせ
ES2862126T3 (es) 2013-10-10 2021-10-07 Acetylon Pharmaceuticals Inc Compuestos de pirimidín-hidroxiamida como inhibidores de histona desacetilasa
EP4137135B1 (en) 2013-10-24 2024-06-05 Mayo Foundation for Medical Education and Research Treatment of polycystic diseases with an hdac6 inhibitor
CR20160308A (es) 2013-12-03 2016-11-08 Acetylon Pharmaceuticals Inc Combinaciones de inhibidores de histona deacetilasa y farmacos inmunomoduladores
US9464073B2 (en) 2014-02-26 2016-10-11 Acetylon Pharmaceuticals, Inc. Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors
CN107205988A (zh) 2014-07-07 2017-09-26 埃斯泰隆制药公司 利用组蛋白脱乙酰酶抑制剂治疗白血病
AU2015356779A1 (en) 2014-12-05 2017-07-13 University of Modena and Reggio Emilia Combinations of histone deacetylase inhibitors and bendamustine for use in the treatment of lymphoma
US10272084B2 (en) 2015-06-01 2019-04-30 Regenacy Pharmaceuticals, Llc Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy
US11813261B2 (en) 2016-04-19 2023-11-14 Acetylon Pharmaceuticals, Inc. HDAC inhibitors, alone or in combination with BTK inhibitors, for treating chronic lymphocytic leukemia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2412010A1 (en) 2000-06-13 2001-12-20 Basf Aktiengesellschaft Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines
BR0207975A (pt) 2001-03-15 2004-06-15 Basf Ag Composto, processo para preparar 5 fenilpiridinas, produto intermediário, agente adequado para combater fungos nocivos fitopatogênicos, e, processo para combater fungos nocivos fitopatogênicos
IL161893A0 (en) * 2001-11-19 2005-11-20 Basf Ag 5-Phenylpyrimidines, agents comprising the same, method for production and use thereof

Also Published As

Publication number Publication date
ATE350370T1 (de) 2007-01-15
AR045100A1 (es) 2005-10-12
AU2004261373A1 (en) 2005-02-10
AP2157A (en) 2010-09-13
IL172848A0 (en) 2006-06-11
CO5660292A2 (es) 2006-07-31
SI1651618T1 (sl) 2007-06-30
PL1651618T3 (pl) 2007-05-31
US7375108B2 (en) 2008-05-20
PE20050882A1 (es) 2005-12-01
EP1651618B1 (de) 2007-01-03
WO2005012261A1 (de) 2005-02-10
CY1106391T1 (el) 2011-10-12
EA010566B1 (ru) 2008-10-30
JP2006528603A (ja) 2006-12-21
AU2004261373B8 (en) 2010-11-04
BRPI0412891A (pt) 2006-10-03
UY28436A1 (es) 2005-02-28
DE502004002570D1 (de) 2007-02-15
ECSP066278A (es) 2006-07-28
AU2004261373B2 (en) 2010-08-19
US20070105873A1 (en) 2007-05-10
DK1651618T3 (da) 2007-05-14
CR8184A (es) 2006-10-06
KR20060052857A (ko) 2006-05-19
CA2532718A1 (en) 2005-02-10
HRP20070057T3 (en) 2007-07-31
MXPA06000038A (es) 2006-03-21
MA27949A1 (fr) 2006-06-01
PT1651618E (pt) 2007-03-30
EP1651618A1 (de) 2006-05-03
TW200516075A (en) 2005-05-16
AP2006003497A0 (en) 2006-02-28
ES2279395T3 (es) 2007-08-16
NZ545103A (en) 2008-06-30

Similar Documents

Publication Publication Date Title
CY1106391T1 (el) 2-υποκατεστημενες πυριμιδινες
EA200600631A1 (ru) 2-галоид-6-алкилфенилзамещённые производные тетрамовой кислоты
EA200870321A1 (ru) Способ получения 4-оксохинолинового соединения
DE60236600D1 (de) Substituierte 1h-dihydropyrazole, ihre herstellung und verwendung
HRP20080664A2 (en) Substituted pyridine herbicides
EA200601125A1 (ru) 6-замещённые циклогексилалкил 2-замещённые хинолиноны и 2-хиноксалиноны в качестве ингибиторов поли(adp-рибоза)полимеразы
EA200700188A1 (ru) Производные замещенного 2-алкилхиназолинона как ингибиторы parp
EA200602038A1 (ru) Азинилимидазоазины и азинилкарбоксамиды
EA200700556A1 (ru) Замещенные бензоилом серин-амиды
EA200700185A1 (ru) Производные хиназолиндиона в качестве ингибиторов parp
ATE433447T1 (de) Pyrimiidinverbindungen
CY1106247T1 (el) Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες
EA200870116A1 (ru) Бициклические гетероарильные соединения
EA200400763A1 (ru) Замещенные фенилпроизводные соединения
EA200700286A1 (ru) Применение замещённых производных 2-пирролидона в качестве фунгицидов и инсектицидов
EA200601007A1 (ru) 7-фенилалкилзамещённые 2-хинолиноны и 2-хиноксалиноны в качестве ингибиторов поли(адф-рибоза)полимеразы
EA200601568A1 (ru) Новые гидрокси-8-гетероарилфенантридины и их применение в качестве ингибиторов pde4
EA200500862A1 (ru) Синоменин и соединения синоменина, синтез и применение
MXPA02011370A (es) Iminoazinas substituidas.
BRPI0516242A (pt) compostos tieno-pirimidina tendo atividade fungicida
BRPI0509731A (pt) pirazol[4,3-d]pirimidinas
DE502005003473D1 (de) 2-substituierte pyrimidine und ihre verwendung als pestizide
EA200501341A1 (ru) Противобактериальные индолоноксазолидиноны, промежуточные соединения для их получения и содержащие их фармацевтические композиции
EA200600018A1 (ru) Производные никотинамида, полезные в качестве ингибиторов фдэ4
TW200613277A (en) 2-substituted pyrimidines, processes for their preparation and their use for controlling harmful fungi

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY MD RU