ECSP066278A - Pirimidinas 2-sustituidas - Google Patents

Pirimidinas 2-sustituidas

Info

Publication number
ECSP066278A
ECSP066278A EC2006006278A ECSP066278A ECSP066278A EC SP066278 A ECSP066278 A EC SP066278A EC 2006006278 A EC2006006278 A EC 2006006278A EC SP066278 A ECSP066278 A EC SP066278A EC SP066278 A ECSP066278 A EC SP066278A
Authority
EC
Ecuador
Prior art keywords
substituted pyrimidines
well
description
definitions indicated
pesticides
Prior art date
Application number
EC2006006278A
Other languages
English (en)
Inventor
Reinhard Stierl
Maria Scherer
I Blasco Jordi Tormo
Thomas Grote
Siegfried Strathmann
Ulrich Schoefl
Carsten Blettner
Markus Gewehr
Andreas Gypser
Joachim Rheinheimer
Frank Schieweck
Anja Schwoegler
Oliver Wagner
Bernd Muller
Peter Schafer
Wassilios Grammenos
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ECSP066278A publication Critical patent/ECSP066278A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invención se refiere a pirimidinas 2-sustituidas de la fórmula I Ien la que el índice n y los sutituyentes R1 hasta R3, así como L tienen las definiciones indicadas en la descripción y R4 corresponde a una de las fórmulas donde Ra, X y Rb tienen las definiciones indicadas en la descripción;así como procedimientos para su obtención, productos pesticidas que las contienen y el uso de las mismas como pesticidas.
EC2006006278A 2003-07-24 2006-01-11 Pirimidinas 2-sustituidas ECSP066278A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10333857 2003-07-24
DE10357714 2003-12-09

Publications (1)

Publication Number Publication Date
ECSP066278A true ECSP066278A (es) 2006-07-28

Family

ID=34117367

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006278A ECSP066278A (es) 2003-07-24 2006-01-11 Pirimidinas 2-sustituidas

Country Status (30)

Country Link
US (1) US7375108B2 (es)
EP (1) EP1651618B1 (es)
JP (1) JP2006528603A (es)
KR (1) KR20060052857A (es)
AP (1) AP2157A (es)
AR (1) AR045100A1 (es)
AT (1) ATE350370T1 (es)
AU (1) AU2004261373B8 (es)
BR (1) BRPI0412891A (es)
CA (1) CA2532718A1 (es)
CO (1) CO5660292A2 (es)
CR (1) CR8184A (es)
CY (1) CY1106391T1 (es)
DE (1) DE502004002570D1 (es)
DK (1) DK1651618T3 (es)
EA (1) EA010566B1 (es)
EC (1) ECSP066278A (es)
ES (1) ES2279395T3 (es)
HR (1) HRP20070057T3 (es)
IL (1) IL172848A0 (es)
MA (1) MA27949A1 (es)
MX (1) MXPA06000038A (es)
NZ (1) NZ545103A (es)
PE (1) PE20050882A1 (es)
PL (1) PL1651618T3 (es)
PT (1) PT1651618E (es)
SI (1) SI1651618T1 (es)
TW (1) TW200516075A (es)
UY (1) UY28436A1 (es)
WO (1) WO2005012261A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080132522A1 (en) * 2004-07-14 2008-06-05 Basf Aktiengesellschaft 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi
CL2007002231A1 (es) * 2006-08-02 2008-04-11 Basf Ag Uso de compuestos derivados de 5-(het) arilpirimidina para combatir hongos daninos; compuestos derivados de 5-(het) arilpirimidina; agente fungicida; y agente farmaceutico.
PT2640709T (pt) * 2010-11-16 2016-07-13 Acetylon Pharmaceuticals Inc Compostos de pirimidina hidroxiamida como inibidores de proteína desacetilase e métodos de utilização dos mesmos
EP3054952B1 (en) 2013-10-08 2022-10-26 Acetylon Pharmaceuticals, Inc. Combinations of histone deacetylase 6 inhibitors and the her2 inhibitor lapatinib for use in the treatment of breast cancer
US9278963B2 (en) 2013-10-10 2016-03-08 Acetylon Pharmaceuticals, Inc. Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors
EP3060217B1 (en) 2013-10-24 2022-06-08 Mayo Foundation for Medical Education and Research Treatment of polycystic diseases with an hdac6 inhibitor
CA2932411A1 (en) 2013-12-03 2015-06-11 Acetylon Pharmaceuticals, Inc. Combinations of histone deacetylase inhibitors and immunomodulatory drugs
US9464073B2 (en) 2014-02-26 2016-10-11 Acetylon Pharmaceuticals, Inc. Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors
EP3166603B1 (en) 2014-07-07 2020-02-12 Acetylon Pharmaceuticals, Inc. Treatment of leukemia with histone deacetylase inhibitors
CA2969790A1 (en) 2014-12-05 2016-06-09 University of Modena and Reggio Emilia Combinations of histone deacetylase inhibitors and bendamustine
US10272084B2 (en) 2015-06-01 2019-04-30 Regenacy Pharmaceuticals, Llc Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy
JP2019515909A (ja) 2016-04-19 2019-06-13 アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． 慢性リンパ性白血病の治療を目的とするｈｄａｃ阻害剤単独またはｂｔｋ阻害剤との配合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU778913B2 (en) 2000-06-13 2004-12-23 Basf Aktiengesellschaft Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines
JP4361736B2 (ja) * 2001-03-15 2009-11-11 ビーエーエスエフ ソシエタス・ヨーロピア ５−フェニルピリミジン、その製造方法、製造のための中間体および有害な菌類を防除するための使用
CN1312134C (zh) 2001-11-19 2007-04-25 巴斯福股份公司 5－苯基嘧啶化合物、包含它们的组合物、其制备方法及其用途

Also Published As

Publication number Publication date
NZ545103A (en) 2008-06-30
US20070105873A1 (en) 2007-05-10
MXPA06000038A (es) 2006-03-21
PL1651618T3 (pl) 2007-05-31
ATE350370T1 (de) 2007-01-15
AP2006003497A0 (en) 2006-02-28
UY28436A1 (es) 2005-02-28
CR8184A (es) 2006-10-06
PT1651618E (pt) 2007-03-30
TW200516075A (en) 2005-05-16
JP2006528603A (ja) 2006-12-21
AU2004261373B8 (en) 2010-11-04
SI1651618T1 (sl) 2007-06-30
EP1651618A1 (de) 2006-05-03
CO5660292A2 (es) 2006-07-31
IL172848A0 (en) 2006-06-11
KR20060052857A (ko) 2006-05-19
PE20050882A1 (es) 2005-12-01
CA2532718A1 (en) 2005-02-10
EP1651618B1 (de) 2007-01-03
US7375108B2 (en) 2008-05-20
CY1106391T1 (el) 2011-10-12
ES2279395T3 (es) 2007-08-16
HRP20070057T3 (en) 2007-07-31
AU2004261373A1 (en) 2005-02-10
MA27949A1 (fr) 2006-06-01
AR045100A1 (es) 2005-10-12
WO2005012261A1 (de) 2005-02-10
BRPI0412891A (pt) 2006-10-03
DK1651618T3 (da) 2007-05-14
EA200600212A1 (ru) 2006-08-25
AP2157A (en) 2010-09-13
DE502004002570D1 (de) 2007-02-15
AU2004261373B2 (en) 2010-08-19
EA010566B1 (ru) 2008-10-30

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