CN1468251A - 一种用于均相检测核酸的特异性双链探针及其实施方法 - Google Patents
一种用于均相检测核酸的特异性双链探针及其实施方法 Download PDFInfo
- Publication number
- CN1468251A CN1468251A CNA018170129A CN01817012A CN1468251A CN 1468251 A CN1468251 A CN 1468251A CN A018170129 A CNA018170129 A CN A018170129A CN 01817012 A CN01817012 A CN 01817012A CN 1468251 A CN1468251 A CN 1468251A
- Authority
- CN
- China
- Prior art keywords
- probe
- oligonucleotide
- sequence
- double
- chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
Description
Claims (15)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN018170129A CN1468251B (zh) | 2000-10-10 | 2001-10-05 | 一种用于均相检测核酸的特异性双链探针及其实施方法 |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN00130711 | 2000-10-10 | ||
CN00130711.8 | 2000-10-10 | ||
CN01101446.6 | 2001-01-13 | ||
CN01101446A CN1348096A (zh) | 2000-10-10 | 2001-01-13 | 一种均相特异性检测核酸的探针及应用方法 |
PCT/US2001/031246 WO2002030946A1 (en) | 2000-10-10 | 2001-10-05 | Specific double-stranded probes for homogeneous detection of nucleic acid and their application methods |
CN018170129A CN1468251B (zh) | 2000-10-10 | 2001-10-05 | 一种用于均相检测核酸的特异性双链探针及其实施方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1468251A true CN1468251A (zh) | 2004-01-14 |
CN1468251B CN1468251B (zh) | 2012-11-21 |
Family
ID=25739622
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN01101446A Pending CN1348096A (zh) | 2000-10-10 | 2001-01-13 | 一种均相特异性检测核酸的探针及应用方法 |
CN018170129A Expired - Fee Related CN1468251B (zh) | 2000-10-10 | 2001-10-05 | 一种用于均相检测核酸的特异性双链探针及其实施方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN01101446A Pending CN1348096A (zh) | 2000-10-10 | 2001-01-13 | 一种均相特异性检测核酸的探针及应用方法 |
Country Status (8)
Country | Link |
---|---|
US (2) | US7799522B2 (zh) |
EP (1) | EP1339732B1 (zh) |
JP (1) | JP3999653B2 (zh) |
CN (2) | CN1348096A (zh) |
AU (2) | AU2001296647B2 (zh) |
BR (1) | BR0114575A (zh) |
CA (1) | CA2424856C (zh) |
WO (1) | WO2002030946A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105506126A (zh) * | 2016-01-12 | 2016-04-20 | 重庆大学 | 具有较大张力的小环形核苷酸探针及其制备方法和应用 |
CN109652516A (zh) * | 2018-12-29 | 2019-04-19 | 中国人民解放军军事科学院军事医学研究院 | 一种双链寡核苷酸核酸探针的结构和用途 |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1348096A (zh) * | 2000-10-10 | 2002-05-08 | 栾国彦 | 一种均相特异性检测核酸的探针及应用方法 |
US9261460B2 (en) * | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
CN1294276C (zh) * | 2003-07-22 | 2007-01-10 | 厦门大学 | 检测核酸的等长双链特异性探针 |
US20070111207A1 (en) * | 2003-07-30 | 2007-05-17 | Interite Inc. | Partially double stranded nucleic acid molecules |
ATE557100T1 (de) | 2003-12-03 | 2012-05-15 | Abbott Lab | Doppelsträngige lineare nukleinsäuresonde und deren verwendung |
WO2005084272A2 (en) * | 2004-02-28 | 2005-09-15 | Wang Chang-Ning J | Nucleic acid complexes |
DE102004026494A1 (de) * | 2004-05-27 | 2005-12-22 | Ruprecht-Karls-Universität Heidelberg | Hochselektiver Nachweis von DNA-Molekülen mit gemischten PNA-DNA-Systemen |
JP2008501679A (ja) * | 2004-06-02 | 2008-01-24 | エーエスエム サイエンティフィック, インコーポレイテッド | 2’−ニトロベンジル改変型リボヌクレオチド |
GB0419325D0 (en) * | 2004-09-01 | 2004-09-29 | Perkinelmer Ltd | A method of analysing a sample including fluorescent labels and apparatus therefor |
GB0510979D0 (en) | 2005-05-28 | 2005-07-06 | Kbiosciences Ltd | Detection system for PCR assay |
EP2029775B1 (en) | 2006-06-05 | 2014-10-15 | California Institute Of Technology | Real time micro arrays |
US11001881B2 (en) | 2006-08-24 | 2021-05-11 | California Institute Of Technology | Methods for detecting analytes |
US7972786B2 (en) * | 2006-07-07 | 2011-07-05 | Brandeis University | Detection and analysis of influenza virus |
US11525156B2 (en) | 2006-07-28 | 2022-12-13 | California Institute Of Technology | Multiplex Q-PCR arrays |
WO2008014485A2 (en) | 2006-07-28 | 2008-01-31 | California Institute Of Technology | Multiplex q-pcr arrays |
US11560588B2 (en) | 2006-08-24 | 2023-01-24 | California Institute Of Technology | Multiplex Q-PCR arrays |
ATE437965T1 (de) | 2006-10-12 | 2009-08-15 | Bio Rad Pasteur | Doppelsträngige sonden zur fluoreszenzdetektion von nukleinsäuren |
JP5013604B2 (ja) * | 2007-07-24 | 2012-08-29 | 株式会社スギヨ | 海藻ペーストの製造方法及びその方法によって得られた海藻ペースト |
WO2010130877A2 (en) * | 2009-05-12 | 2010-11-18 | Abacus Diagnostica Oy | Method for detecting nucleic acids |
CN101845498B (zh) * | 2010-04-29 | 2013-05-08 | 厦门艾德生物医药科技有限公司 | 一种用于核酸特异识别检测的探针 |
DE102010025161A1 (de) * | 2010-06-25 | 2011-12-29 | Qiagen Gmbh | Verfahren zum Nachweis von Ribonukleinsäuren |
US20120052502A1 (en) * | 2010-08-30 | 2012-03-01 | Samsung Techwin Co., Ltd. | Real-time pcr detection using stabilized probes |
US9284602B2 (en) | 2010-10-27 | 2016-03-15 | President And Fellows Of Harvard College | Compositions of toehold primer duplexes and methods of use |
US9796748B2 (en) | 2011-05-02 | 2017-10-24 | President And Fellows Of Harvard College | Spatial sequestration of dynamic nucleic acid circuits |
CN108342453A (zh) | 2011-05-09 | 2018-07-31 | 富鲁达公司 | 基于探针的核酸检测 |
US9644231B2 (en) | 2011-05-09 | 2017-05-09 | Fluidigm Corporation | Nucleic acid detection using probes |
DE102011078342A1 (de) * | 2011-06-29 | 2013-01-03 | Aj Innuscreen Gmbh | Rehybridisierendes Sondensystem zur qualitativen und quantitativen Messung von spezifischen Nukleinsäuren in Echtzeit |
JP6085564B2 (ja) | 2011-10-31 | 2017-02-22 | 栄研化学株式会社 | 標的核酸の検出法 |
MX2015001961A (es) * | 2012-08-16 | 2015-09-10 | Nvs Technologies Inc | Metodos y sistemas para ensayos. |
CN108588177B (zh) | 2013-08-12 | 2022-02-18 | 伯乐生命医学产品有限公司 | 具有碱基配对的寡聚体的扩增报告子 |
JP5928906B2 (ja) * | 2013-08-27 | 2016-06-01 | 横河電機株式会社 | 核酸配列計測方法、核酸配列計測用デバイス、核酸配列計測用デバイスの製造方法および核酸配列計測装置 |
CA2934226C (en) * | 2013-12-16 | 2022-12-06 | William Marsh Rice University | Fine-tuned ultraspecific nucleic acid hybridization probes |
CN114196732A (zh) * | 2015-03-19 | 2022-03-18 | 康代思锐公司 | 用于核酸检测的被编码的双链探针及其用途 |
US9708647B2 (en) | 2015-03-23 | 2017-07-18 | Insilixa, Inc. | Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays |
US9499861B1 (en) | 2015-09-10 | 2016-11-22 | Insilixa, Inc. | Methods and systems for multiplex quantitative nucleic acid amplification |
CN113832215B (zh) | 2016-02-09 | 2024-02-06 | 荣研化学株式会社 | 对目标核酸进行检测的方法 |
WO2017155858A1 (en) | 2016-03-07 | 2017-09-14 | Insilixa, Inc. | Nucleic acid sequence identification using solid-phase cyclic single base extension |
JP6584986B2 (ja) * | 2016-03-18 | 2019-10-02 | 株式会社東芝 | 核酸検出方法 |
CN109415772A (zh) | 2016-06-16 | 2019-03-01 | 生物辐射实验室股份有限公司 | 检测鼠伤寒沙门氏菌的方法 |
GB201617491D0 (en) * | 2016-10-14 | 2016-11-30 | Moorlodge Biotech Ventures Limited | Amplification of nucleic acids |
CN107236815A (zh) * | 2017-07-18 | 2017-10-10 | 江西贤聚景欣医药生物科技有限公司 | 用于靶核酸序列检测的多重淬灭荧光探针及方法 |
KR101899371B1 (ko) | 2017-07-25 | 2018-10-29 | (주)엔바이오텍 | 핵산 복합체 페어, 핵산 복합체 페어를 포함하는 pcr용 키트, 및 핵산 복합체 페어를 이용한 타겟 검출 방법 |
JP7035972B2 (ja) * | 2018-11-09 | 2022-03-15 | 横河電機株式会社 | 核酸配列計測用デバイス |
EP3937780A4 (en) | 2019-03-14 | 2022-12-07 | InSilixa, Inc. | METHODS AND SYSTEMS FOR TIMED FLUORESCENCE-BASED DETECTION |
CA3150825A1 (en) | 2019-10-02 | 2021-04-08 | Fred Russell Kramer | Assay methods and kits for detecting rare sequence variants |
WO2022132955A2 (en) * | 2020-12-16 | 2022-06-23 | Proof Diagnostics, Inc. | Coronavirus rapid diagnostics |
WO2023023673A2 (en) | 2021-08-20 | 2023-02-23 | Kasa Bio, L.L.C. | Compositions and methods for multiplex detection of mirna and other polynucelotides |
EP4148143A1 (en) * | 2021-09-13 | 2023-03-15 | Consejo Superior De Investigaciones Científicas (CSIC) | Polypurine reverse hoogsteen hairpins and parallel clamps and their use as biosensors |
US20230313283A1 (en) * | 2022-02-28 | 2023-10-05 | Trustees Of Boston University | Isothermal nucleic acid detection assays and uses thereof |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1190838A (en) | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
US4766062A (en) | 1984-05-07 | 1988-08-23 | Allied Corporation | Displacement polynucleotide assay method and polynucleotide complex reagent therefor |
EP0221108B1 (en) | 1985-05-02 | 1993-09-01 | Genetics Institute, Inc. | Process and nucleic acid construct for producing reagent complexes useful in determining target nucleotide sequences |
CA1273552A (en) | 1985-12-23 | 1990-09-04 | Michael J. Heller | Fluorescent stokes shift probes for polynucleotide hybridization assays |
DE3785591T2 (de) | 1986-01-10 | 1993-09-02 | Amoco Corp | Kompetitiver homogener test. |
EP0601889A2 (en) | 1992-12-10 | 1994-06-15 | Maine Medical Center Research Institute | Nucleic acid probes |
ES2386007T3 (es) * | 1993-11-12 | 2012-08-07 | Phri Properties, Inc. | Sonda de hibridación para la detección de ácido nucléico, tallos universales, métodos y kits |
US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
EP0826066B1 (en) | 1995-05-05 | 2000-09-13 | The Perkin-Elmer Corporation | Methods and reagents for combined pcr amplification and hybridization probing assay |
US5716784A (en) | 1996-02-05 | 1998-02-10 | The Perkin-Elmer Corporation | Fluorescence detection assay for homogeneous PCR hybridization systems |
DE69734576T2 (de) * | 1996-03-01 | 2006-08-03 | E.I. Dupont De Nemours And Co., Wilmington | Methode zur vervielfältigung und zum nachweis eines gewünschten nukleinsäurefragments |
JP3898228B2 (ja) | 1996-04-12 | 2007-03-28 | ザ パブリック ヘルス リサーチ インスティチュート オブ ザ シティー オブ ニューヨーク インク | 検出プローブ、キット及びアッセイ |
US7803528B1 (en) * | 1997-02-28 | 2010-09-28 | Quest Diagnostics Incorporated | Fluorescence energy transfer by competitive hybridization |
WO1999049293A2 (en) * | 1998-03-24 | 1999-09-30 | Boston Probes, Inc. | Methods, kits and compositions pertaining to detection complexes |
GB9819417D0 (en) | 1998-09-07 | 1998-10-28 | Secr Defence | Reaction method |
US6277607B1 (en) | 1999-05-24 | 2001-08-21 | Sanjay Tyagi | High specificity primers, amplification methods and kits |
CN1348096A (zh) | 2000-10-10 | 2002-05-08 | 栾国彦 | 一种均相特异性检测核酸的探针及应用方法 |
US6593091B2 (en) * | 2001-09-24 | 2003-07-15 | Beckman Coulter, Inc. | Oligonucleotide probes for detecting nucleic acids through changes in flourescence resonance energy transfer |
-
2001
- 2001-01-13 CN CN01101446A patent/CN1348096A/zh active Pending
- 2001-10-05 BR BR0114575-4A patent/BR0114575A/pt not_active IP Right Cessation
- 2001-10-05 AU AU2001296647A patent/AU2001296647B2/en not_active Ceased
- 2001-10-05 CA CA2424856A patent/CA2424856C/en not_active Expired - Fee Related
- 2001-10-05 US US10/398,832 patent/US7799522B2/en not_active Expired - Lifetime
- 2001-10-05 JP JP2002534331A patent/JP3999653B2/ja not_active Expired - Fee Related
- 2001-10-05 AU AU9664701A patent/AU9664701A/xx active Pending
- 2001-10-05 WO PCT/US2001/031246 patent/WO2002030946A1/en active Application Filing
- 2001-10-05 CN CN018170129A patent/CN1468251B/zh not_active Expired - Fee Related
- 2001-10-05 EP EP01977535A patent/EP1339732B1/en not_active Expired - Lifetime
-
2010
- 2010-08-11 US US12/854,619 patent/US9157112B2/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105506126A (zh) * | 2016-01-12 | 2016-04-20 | 重庆大学 | 具有较大张力的小环形核苷酸探针及其制备方法和应用 |
CN109652516A (zh) * | 2018-12-29 | 2019-04-19 | 中国人民解放军军事科学院军事医学研究院 | 一种双链寡核苷酸核酸探针的结构和用途 |
Also Published As
Publication number | Publication date |
---|---|
CN1348096A (zh) | 2002-05-08 |
JP3999653B2 (ja) | 2007-10-31 |
AU2001296647B2 (en) | 2006-03-16 |
US20040023269A1 (en) | 2004-02-05 |
BR0114575A (pt) | 2004-01-06 |
JP2004511227A (ja) | 2004-04-15 |
CA2424856A1 (en) | 2002-04-18 |
CA2424856C (en) | 2014-03-11 |
CN1468251B (zh) | 2012-11-21 |
WO2002030946A1 (en) | 2002-04-18 |
US7799522B2 (en) | 2010-09-21 |
EP1339732A1 (en) | 2003-09-03 |
EP1339732B1 (en) | 2012-08-01 |
US9157112B2 (en) | 2015-10-13 |
EP1339732A4 (en) | 2004-04-21 |
AU9664701A (en) | 2002-04-22 |
US20110129828A1 (en) | 2011-06-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1468251B (zh) | 一种用于均相检测核酸的特异性双链探针及其实施方法 | |
EP2789689B1 (en) | Chimeric primers with hairpin conformations and methods of using same | |
JP4634340B2 (ja) | 発光修飾剤並びに核酸検出、増幅および分析におけるその使用 | |
CA2375027C (en) | High specificity primers, amplification methods and kits | |
AU2010290277B2 (en) | TD probe and its uses | |
US20080274458A1 (en) | Nucleic acid quantitation methods | |
CN100588953C (zh) | 生物芯片检测单核苷酸多态性的方法 | |
AU2001296647A1 (en) | Specific double-stranded probes for homogeneous detection of nucleic acid and their application methods | |
EP1698897B1 (en) | Novel mixtures for assaying nucleic acid, novel method of assaying nucleic acid with the use of the same and nucleic acid probe to be used therefor | |
JP2010510778A (ja) | Dnaの増幅のための二重機能プライマーおよび使用法 | |
US20140017689A1 (en) | Method for detecting nucleic acids | |
Vet et al. | Molecular beacons: colorful analysis of nucleic acids | |
US20220282307A1 (en) | Methods and probes for performing pcr with melt analysis for increased multiplexing | |
KR102323375B1 (ko) | 다중 프로브 | |
CN101671744A (zh) | 一种用于核酸实时检测的探针 | |
KR100906749B1 (ko) | 인터컬레이팅 형광염료가 표지된 프로브를 이용한 핵산 증폭 측정 방법 | |
US7220540B1 (en) | Methods for detecting bacteriophage MS2 | |
US7642082B1 (en) | Methods for determining the presence of staphylococcal enterotoxin A gene in a sample | |
Sergeevich et al. | Real-time PCR: advantages and limitations | |
KR20240058024A (ko) | 대장균의 o115 혈청형 신속 동정용 프라이머 세트 및 이를 이용한 대장균의 혈청형 동정 방법 | |
KR20240058022A (ko) | 대장균의 o105, o10, o119, o132, o150, o35, o25, o36, o177, o26 또는 o2 혈청형 신속 동정용 프라이머 세트 및 이를 이용한 대장균의 혈청형 동정 방법 | |
KR20240058021A (ko) | 대장균의 o103, o121, o123, o136, o156, o168, o170, o174, o3, o40, o64, o66, o6, o78, o80, o82, o88, o8, o91, o181 또는 o111 혈청형 신속 동정용 프라이머 세트 및 이를 이용한 대장균의 혈청형 동정 방법 | |
KR20240058020A (ko) | 대장균의 o146 또는 o51 혈청형 신속 동정용 프라이머 세트 및 이를 이용한 대장균의 혈청형 동정 방법 | |
KR20240058025A (ko) | 대장균의 o110, o113, o167 또는 o116 혈청형 신속 동정용 프라이머 세트 및 이를 이용한 대장균의 혈청형 동정 방법 | |
KR20240058023A (ko) | 대장균의 O104, O124, O55, O157, O128ab, O76, O185, O130, O81, O11 또는 O153 혈청형 신속 동정용 프라이머 세트 및 이를 이용한 대장균의 혈청형 동정 방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: NEW JERSEY MEDICAL AND DENTAL UNIVERSITY Free format text: FORMER OWNER: NEW YORK PUBLIC SANITARY ACADEMY CO., LTD. Effective date: 20070608 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20070608 Address after: new jersey Applicant after: New York Public Sanitary Academy Co., Ltd. Address before: new jersey Applicant before: New York Public Sanitary Academy Co., Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20121121 Termination date: 20191005 |
|
CF01 | Termination of patent right due to non-payment of annual fee |