CN1374874A - 使用脂肪酸/氨基酸皂类提高局部药物组合物的抗菌效力 - Google Patents

使用脂肪酸/氨基酸皂类提高局部药物组合物的抗菌效力 Download PDF

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Publication number
CN1374874A
CN1374874A CN00813117A CN00813117A CN1374874A CN 1374874 A CN1374874 A CN 1374874A CN 00813117 A CN00813117 A CN 00813117A CN 00813117 A CN00813117 A CN 00813117A CN 1374874 A CN1374874 A CN 1374874A
Authority
CN
China
Prior art keywords
fatty acid
acid
amino acid
agent
raising
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00813117A
Other languages
English (en)
Chinese (zh)
Inventor
E·J·卡斯特罗
S·H·格尔森
W·W·汉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of CN1374874A publication Critical patent/CN1374874A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN00813117A 1999-09-21 2000-09-11 使用脂肪酸/氨基酸皂类提高局部药物组合物的抗菌效力 Pending CN1374874A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39901399A 1999-09-21 1999-09-21
US09/399,013 1999-09-21

Publications (1)

Publication Number Publication Date
CN1374874A true CN1374874A (zh) 2002-10-16

Family

ID=23577764

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00813117A Pending CN1374874A (zh) 1999-09-21 2000-09-11 使用脂肪酸/氨基酸皂类提高局部药物组合物的抗菌效力

Country Status (10)

Country Link
EP (1) EP1214094A1 (fr)
JP (1) JP2003509474A (fr)
CN (1) CN1374874A (fr)
AR (1) AR025713A1 (fr)
AU (1) AU7363700A (fr)
BR (1) BR0014117A (fr)
CA (1) CA2391976A1 (fr)
PL (1) PL354365A1 (fr)
TR (1) TR200200724T2 (fr)
WO (1) WO2001021209A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101175474B (zh) * 2005-03-10 2011-09-07 3M创新有限公司 降低微生物污染的方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444710B1 (en) 1998-10-27 2002-09-03 Alcon Manufacturing, Ltd. Use of certain fatty acid/amino acid soaps to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions
US7977376B2 (en) 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
TWI231759B (en) 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
FR2837710B1 (fr) * 2002-03-26 2005-07-08 Innovations Pharma Ag Composition topique a base de resines echangeuses d'ions, notamment pour le traitement des erythemes
CN103079595B (zh) * 2010-08-27 2015-11-25 若素制药株式会社 滴眼用水性组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4209722C3 (de) * 1992-03-25 1997-06-19 Medproject Pharma Entwicklungs Tropfbares Gel für die Augenheilkunde
US5520920A (en) * 1992-08-28 1996-05-28 Alcon Laboratories, Inc. Use of certain anionic surfactants to enhance antimicrobial effectiveness of ophthalmic compositions
US5504113A (en) * 1994-03-02 1996-04-02 Allergan, Inc. Enhancement of benzalkonium chloride preservative activity in formulations containing an incompatible drug
JPH0977725A (ja) * 1995-09-13 1997-03-25 Ajinomoto Co Inc 脂肪酸リジン塩の製造方法
US6284749B1 (en) * 1998-10-27 2001-09-04 Alcon Manufacturing, Ltd. Preservative system for topically administrable pharmaceutical compositions containing a fatty acid/amino acid soap

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101175474B (zh) * 2005-03-10 2011-09-07 3M创新有限公司 降低微生物污染的方法

Also Published As

Publication number Publication date
AR025713A1 (es) 2002-12-11
TR200200724T2 (tr) 2002-06-21
WO2001021209A1 (fr) 2001-03-29
CA2391976A1 (fr) 2001-03-29
EP1214094A1 (fr) 2002-06-19
JP2003509474A (ja) 2003-03-11
BR0014117A (pt) 2002-05-14
PL354365A1 (en) 2004-01-12
AU7363700A (en) 2001-04-24

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