CN1349423A - 包含曲马多物质和选择性cox－2抑制剂药物的组合物 - Google Patents

包含曲马多物质和选择性cox－2抑制剂药物的组合物 Download PDF

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Publication number
CN1349423A
CN1349423A CN00807066A CN00807066A CN1349423A CN 1349423 A CN1349423 A CN 1349423A CN 00807066 A CN00807066 A CN 00807066A CN 00807066 A CN00807066 A CN 00807066A CN 1349423 A CN1349423 A CN 1349423A
Authority
CN
China
Prior art keywords
pharmaceutical composition
inhibitor
tramadol
medicine
selective cox
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00807066A
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English (en)
Chinese (zh)
Inventor
E·E·科德
R·P·马蒂内兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
3 Dimensional Pharmaceuticals Inc
Original Assignee
3 Dimensional Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3 Dimensional Pharmaceuticals Inc filed Critical 3 Dimensional Pharmaceuticals Inc
Publication of CN1349423A publication Critical patent/CN1349423A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN00807066A 1999-03-01 2000-02-29 包含曲马多物质和选择性cox－2抑制剂药物的组合物 Pending CN1349423A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12202699P 1999-03-01 1999-03-01
US60/122,026 1999-03-01

Publications (1)

Publication Number Publication Date
CN1349423A true CN1349423A (zh) 2002-05-15

Family

ID=22400139

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00807066A Pending CN1349423A (zh) 1999-03-01 2000-02-29 包含曲马多物质和选择性cox－2抑制剂药物的组合物

Country Status (9)

Country Link
EP (1) EP1156855A1 (ja)
JP (1) JP2002538176A (ja)
CN (1) CN1349423A (ja)
AU (1) AU3384200A (ja)
CA (1) CA2364127A1 (ja)
HK (1) HK1040945A1 (ja)
MX (1) MXPA01008903A (ja)
NZ (1) NZ513924A (ja)
WO (1) WO2000051685A1 (ja)

Cited By (2)

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CN102573824A (zh) * 2009-10-16 2012-07-11 埃斯蒂文博士实验室股份有限公司 治疗疼痛的包含曲马多和塞来昔布的组合物
CN102946871A (zh) * 2010-06-04 2013-02-27 埃斯蒂文博士实验室股份有限公司 曲马多和昔布类（Coxibs）的共晶体的药物组合物

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US8795332B2 (en) 2002-09-30 2014-08-05 Ethicon, Inc. Barbed sutures
CA2348979A1 (en) * 1998-11-02 2000-05-11 Merck & Co., Inc. Method of treating migraines and pharmaceutical compositions
WO2003048113A1 (en) 2001-11-30 2003-06-12 Sepracor Inc. Tramadol analogs and uses thereof
US6773450B2 (en) 2002-08-09 2004-08-10 Quill Medical, Inc. Suture anchor and method
US8100940B2 (en) 2002-09-30 2012-01-24 Quill Medical, Inc. Barb configurations for barbed sutures
AU2003283410A1 (en) 2002-11-22 2004-06-18 Grunenthal Gmbh Combination of selected analgesics and cox-ii inhibitors
ATE342722T1 (de) 2003-05-07 2006-11-15 Osteologix As Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
US7205329B2 (en) 2003-05-30 2007-04-17 Microbia, Inc. Modulators of CRTH2 activity
US20070293542A1 (en) * 2003-10-16 2007-12-20 Cali Brian M Selective Cox-2 Inhibitors
CA2566438C (en) 2004-05-14 2014-12-09 Angiotech Pharmaceuticals, Inc. Suture methods and devices
US8765178B2 (en) 2006-07-19 2014-07-01 Watson Laboratories, Inc. Controlled release formulations and associated methods
SE532177C2 (sv) * 2006-07-24 2009-11-10 P & P Ab En punkteringsanordning för en uppblåsbar enhet
KR20090054984A (ko) 2006-08-07 2009-06-01 아이언우드 파마슈티컬스, 인코포레이티드 인돌 화합물
US20080255612A1 (en) 2007-04-13 2008-10-16 Angiotech Pharmaceuticals, Inc. Self-retaining systems for surgical procedures
US8777987B2 (en) 2007-09-27 2014-07-15 Ethicon, Inc. Self-retaining sutures including tissue retainers having improved strength
US8916077B1 (en) 2007-12-19 2014-12-23 Ethicon, Inc. Self-retaining sutures with retainers formed from molten material
US8118834B1 (en) 2007-12-20 2012-02-21 Angiotech Pharmaceuticals, Inc. Composite self-retaining sutures and method
EP2249712B8 (en) 2008-02-21 2018-12-26 Ethicon LLC Method and apparatus for elevating retainers on self-retaining sutures
CN102056552B (zh) 2008-04-15 2013-07-03 伊西康有限责任公司 具有双向保持器或单向保持器的自保持缝合线
AR073277A1 (es) * 2008-09-05 2010-10-28 Gruenenthal Gmbh Combinacion farmaceutica que contiene el 6-dimetilaminometil-1-(3-metoxi-fenil)-ciclohexano-1,3-diol y paracetamol, y uso
KR20110065488A (ko) * 2008-09-05 2011-06-15 그뤼넨탈 게엠베하 6-디메틸아미노메틸-1-(3-메톡시-페닐)-사이클로헥산-1,3-디올 및 ｎｓａｉｄ를 포함하는 약제학적 병용물
EP2177215A1 (en) 2008-10-17 2010-04-21 Laboratorios Del. Dr. Esteve, S.A. Co-crystals of tramadol and NSAIDs
EP3420923A1 (en) 2008-11-03 2019-01-02 Ethicon, LLC Length of self-retaining suture and device for using the same
SI2488169T1 (sl) * 2009-10-16 2013-05-31 Laboratorios Del Dr. Esteve, S.A. Ko - kristali iz tramadola in koksibov
WO2011090628A2 (en) 2009-12-29 2011-07-28 Angiotech Pharmaceuticals, Inc. Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods
EP2353594A1 (en) 2010-02-09 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Compositions comprising tramadol and the co-crystal of celecoxib and L-proline in the treatment of pain
KR102045300B1 (ko) 2010-05-04 2019-11-18 에티컨, 엘엘씨 레이저 커팅된 리테이너를 갖는 자가-유지형 시스템
BR112012031606B1 (pt) 2010-06-11 2020-11-10 Ethicon Llc distribuidor de sutura
CN103747746B (zh) 2010-11-03 2017-05-10 伊西康有限责任公司 药物洗脱自固位缝合线及其相关方法
CA2817036C (en) 2010-11-09 2019-01-15 Ethicon, Llc Emergency self-retaining sutures and packaging
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MX2016006464A (es) * 2016-05-18 2017-11-17 Laboratorios Liomont S A De C V Composicion farmaceutica de una combinacion de clorhidrato de tramadol-etoricoxib para el tratamiento del dolor.
CN117017971A (zh) * 2017-09-15 2023-11-10 晶体基因技术株式会社 用于治疗急性或慢性疼痛的药物组合物
MX2018013070A (es) 2017-12-29 2019-10-15 Gruenenthal Gmbh Combinación farmacéutica que comprende clorhidrato de tramadol de liberación extendida y etoricoxib de liberación inmediata, y su uso para el tratamiento del dolor.
KR102631399B1 (ko) 2018-03-30 2024-02-01 씨지인바이츠 주식회사 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102573824A (zh) * 2009-10-16 2012-07-11 埃斯蒂文博士实验室股份有限公司 治疗疼痛的包含曲马多和塞来昔布的组合物
CN107050006A (zh) * 2009-10-16 2017-08-18 埃斯蒂文博士实验室股份有限公司 治疗疼痛的包含曲马多和塞来昔布的组合物
CN102946871A (zh) * 2010-06-04 2013-02-27 埃斯蒂文博士实验室股份有限公司 曲马多和昔布类（Coxibs）的共晶体的药物组合物

Also Published As

Publication number Publication date
AU3384200A (en) 2000-09-21
CA2364127A1 (en) 2000-09-08
NZ513924A (en) 2001-09-28
JP2002538176A (ja) 2002-11-12
HK1040945A1 (zh) 2002-06-28
WO2000051685A1 (en) 2000-09-08
EP1156855A1 (en) 2001-11-28
MXPA01008903A (es) 2003-07-21

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