CN1341209A - 使用偏振光对组织成像 - Google Patents

使用偏振光对组织成像 Download PDF

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Publication number
CN1341209A
CN1341209A CN00804259A CN00804259A CN1341209A CN 1341209 A CN1341209 A CN 1341209A CN 00804259 A CN00804259 A CN 00804259A CN 00804259 A CN00804259 A CN 00804259A CN 1341209 A CN1341209 A CN 1341209A
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CN
China
Prior art keywords
light
tissue
fiber
backscattered
optical
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00804259A
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English (en)
Chinese (zh)
Inventor
斯蒂芬·F·富尔格休姆
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Newton Laboratories Inc
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Newton Laboratories Inc
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Filing date
Publication date
Application filed by Newton Laboratories Inc filed Critical Newton Laboratories Inc
Publication of CN1341209A publication Critical patent/CN1341209A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407—Optical details
    • G02B23/2461—Illumination
    • G02B23/2469—Illumination using optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00096—Optical elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00097—Sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00172—Optical arrangements with means for scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00186—Optical arrangements with imaging filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407—Optical details
    • G02B23/2423—Optical details of the distal end
    • G02B23/243—Objectives for endoscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4792—Polarisation of scatter light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Astronomy & Astrophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Endoscopes (AREA)
  • Eye Examination Apparatus (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
CN00804259A 1999-01-25 2000-01-25 使用偏振光对组织成像 Pending CN1341209A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11722199P 1999-01-25 1999-01-25
US60/117,221 1999-01-25

Publications (1)

Publication Number Publication Date
CN1341209A true CN1341209A (zh) 2002-03-20

Family

ID=22371613

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00804259A Pending CN1341209A (zh) 1999-01-25 2000-01-25 使用偏振光对组织成像

Country Status (9)

Country Link
EP (1) EP1153280A2 (https=)
JP (1) JP2002535645A (https=)
KR (1) KR20010110346A (https=)
CN (1) CN1341209A (https=)
AU (1) AU2628200A (https=)
CA (1) CA2371782A1 (https=)
HK (1) HK1041727A1 (https=)
NZ (1) NZ513118A (https=)
WO (1) WO2000043750A2 (https=)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100443041C (zh) * 2004-05-26 2008-12-17 吴冈 具有测量功能的内窥镜系统及其测量方法
CN100506150C (zh) * 2007-04-28 2009-07-01 马剑文 活体组织光学检测装置及其工作方法
CN101326428B (zh) * 2005-10-11 2011-05-18 杜克大学 用于内窥镜的角度分辨低相干干涉测量的系统和方法
CN102227625A (zh) * 2008-12-02 2011-10-26 皇家飞利浦电子股份有限公司 用于通过受抑全内反射来探测目标颗粒的传感器装置
CN101641043B (zh) * 2007-03-12 2012-01-11 皇家飞利浦电子股份有限公司 用于复合上皮早期癌症的诊断和分期的系统
CN102749287A (zh) * 2003-06-04 2012-10-24 突慧公司 利用光的传播模式测量物质中的光学不均匀性和其他属性
CN103596487A (zh) * 2011-07-15 2014-02-19 奥林巴斯医疗株式会社 探头
CN104219988A (zh) * 2012-05-25 2014-12-17 奥林巴斯医疗株式会社 测量探头
CN104280350A (zh) * 2013-07-03 2015-01-14 庞小峰 一种特殊锐化的癌症早期诊断和治疗效果检查的装置
CN104619235A (zh) * 2012-09-13 2015-05-13 奥林巴斯株式会社 测量探头以及生物体光学测量系统
WO2018126497A1 (zh) * 2017-01-09 2018-07-12 清华大学深圳研究生院 一种头端调制的内窥偏振成像系统及测量方法
CN113075097A (zh) * 2021-03-22 2021-07-06 厦门理工学院 一种基于散射光偏振检测的粒径测量方法、装置及设备

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AU2001294997A1 (en) * 2000-08-14 2002-03-13 Oralscan Laboratories, Inc. Detection of epithelial dysplasia
IL157158A0 (en) * 2001-03-02 2004-02-08 Spectrx Inc System and method for determining tissue characteristics
US7404929B2 (en) 2002-01-18 2008-07-29 Newton Laboratories, Inc. Spectroscopic diagnostic methods and system based on scattering of polarized light
US7333189B2 (en) 2002-01-18 2008-02-19 Pentax Corporation Spectroscopic diagnostic methods and system
WO2003104775A1 (en) * 2002-06-08 2003-12-18 Korea Basic Science Institute Method for protein chip analysis by using surface plasmon resonance spectroscopic imaging technology
JP4535697B2 (ja) * 2003-07-23 2010-09-01 オリンパス株式会社 生体組織の光散乱観測内視鏡装置
EP1670347A4 (en) * 2003-09-19 2011-05-18 Gen Hospital Corp FLUORESCENCE POLARIZATION DISPLAY DEVICES AND METHOD
WO2007014213A2 (en) * 2005-07-25 2007-02-01 Massachusetts Institute Of Technology Tri modal spectroscopic imaging
JP4796652B2 (ja) * 2007-02-20 2011-10-19 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ サンプル中の光学的な深さを評価する光学装置
DE202008009859U1 (de) * 2007-12-21 2009-03-05 Berthold Technologies Gmbh & Co. Kg Vorrichtung zur wahlweisen Messung von insbesondere Lumineszenz- und/oder Fluoreszenzstrahlung
JP4575474B2 (ja) * 2008-06-11 2010-11-04 国立大学法人東京工業大学 生体組織識別装置および方法
JP2010025867A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
JP5191831B2 (ja) * 2008-07-23 2013-05-08 オリンパスメディカルシステムズ株式会社 被検体観測装置及び被検体観測装置の作動方法
KR101109968B1 (ko) 2008-07-23 2012-02-17 올림푸스 메디칼 시스템즈 가부시키가이샤 피검체 관측 장치 및 피검체 관측 방법
JP5532479B2 (ja) * 2010-03-31 2014-06-25 住友化学株式会社 金型検査方法、防眩製品ヘイズ予測方法および防眩製品反射像鮮明度予測方法
WO2012057150A1 (ja) * 2010-10-29 2012-05-03 オリンパス株式会社 光学測定装置およびプローブ
EP2823747A4 (en) * 2012-03-07 2015-04-22 Olympus Corp PROBE
CN104159500B (zh) * 2012-03-08 2018-08-07 皇家飞利浦有限公司 用于确定组织的特性的装置
WO2013152395A1 (en) 2012-04-13 2013-10-17 Baker Idi Heart & Diabetes Institute Holdings Limited Atherosclerotic plaque detection
DE102012221527A1 (de) * 2012-11-26 2014-06-12 Heine Optotechnik Gmbh & Co Kg Optisches Diagnoseinstrument
US9921148B2 (en) 2013-04-21 2018-03-20 Mobileodt Ltd. Polarized light imaging apparatus and methods thereof for separating light from a surface of a sample its deeper diffuse layers
KR101503272B1 (ko) 2013-07-26 2015-03-18 연세대학교 원주산학협력단 관절염 진단을 위한 다중 모드 광 영상장치
CN119781177A (zh) 2017-08-31 2025-04-08 梅特兰兹股份有限公司 透射型超表面透镜集成
SG11202013228XA (en) 2018-07-02 2021-01-28 Metalenz Inc Metasurfaces for laser speckle reduction
KR20220035971A (ko) 2019-07-26 2022-03-22 메탈렌츠 인코포레이티드 개구-메타 표면 및 하이브리드 굴절-메타 표면 이미징 시스템
WO2022027094A1 (en) 2020-08-04 2022-02-10 Baker Heart and Diabetes Institute Guidewire sensing apparatus
CN120188073A (zh) 2022-03-31 2025-06-20 梅特兰兹股份有限公司 偏振分选超颖表面微透镜阵列设备

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102749287B (zh) * 2003-06-04 2015-08-19 广东永士达医疗科技有限公司 利用光的传播模式测量物质中的光学不均匀性和其他属性
CN102749287A (zh) * 2003-06-04 2012-10-24 突慧公司 利用光的传播模式测量物质中的光学不均匀性和其他属性
CN100443041C (zh) * 2004-05-26 2008-12-17 吴冈 具有测量功能的内窥镜系统及其测量方法
CN101326428B (zh) * 2005-10-11 2011-05-18 杜克大学 用于内窥镜的角度分辨低相干干涉测量的系统和方法
CN101641043B (zh) * 2007-03-12 2012-01-11 皇家飞利浦电子股份有限公司 用于复合上皮早期癌症的诊断和分期的系统
CN100506150C (zh) * 2007-04-28 2009-07-01 马剑文 活体组织光学检测装置及其工作方法
CN102227625A (zh) * 2008-12-02 2011-10-26 皇家飞利浦电子股份有限公司 用于通过受抑全内反射来探测目标颗粒的传感器装置
CN103596487A (zh) * 2011-07-15 2014-02-19 奥林巴斯医疗株式会社 探头
CN103596487B (zh) * 2011-07-15 2015-11-25 奥林巴斯株式会社 探头
CN104219988A (zh) * 2012-05-25 2014-12-17 奥林巴斯医疗株式会社 测量探头
CN104619235A (zh) * 2012-09-13 2015-05-13 奥林巴斯株式会社 测量探头以及生物体光学测量系统
US10149619B2 (en) 2012-09-13 2018-12-11 Olympus Corporation Measurement probe and biological optical measurement system
CN104280350A (zh) * 2013-07-03 2015-01-14 庞小峰 一种特殊锐化的癌症早期诊断和治疗效果检查的装置
WO2018126497A1 (zh) * 2017-01-09 2018-07-12 清华大学深圳研究生院 一种头端调制的内窥偏振成像系统及测量方法
CN113075097A (zh) * 2021-03-22 2021-07-06 厦门理工学院 一种基于散射光偏振检测的粒径测量方法、装置及设备

Also Published As

Publication number Publication date
NZ513118A (en) 2004-02-27
JP2002535645A (ja) 2002-10-22
EP1153280A2 (en) 2001-11-14
WO2000043750A3 (en) 2000-11-23
CA2371782A1 (en) 2000-07-27
WO2000043750A2 (en) 2000-07-27
AU2628200A (en) 2000-08-07
HK1041727A1 (zh) 2002-07-19
KR20010110346A (ko) 2001-12-13
WO2000043750A9 (en) 2001-08-30

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