CN1341120A - 骨刺激因子 - Google Patents

骨刺激因子 Download PDF

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Publication number
CN1341120A
CN1341120A CN00802780A CN00802780A CN1341120A CN 1341120 A CN1341120 A CN 1341120A CN 00802780 A CN00802780 A CN 00802780A CN 00802780 A CN00802780 A CN 00802780A CN 1341120 A CN1341120 A CN 1341120A
Authority
CN
China
Prior art keywords
polypeptide
seq
amino acid
dna
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00802780A
Other languages
English (en)
Chinese (zh)
Inventor
彻克·兴·泰姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osteopharm Inc
Original Assignee
Osteopharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osteopharm Inc filed Critical Osteopharm Inc
Publication of CN1341120A publication Critical patent/CN1341120A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN00802780A 1999-01-13 2000-01-13 骨刺激因子 Pending CN1341120A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/229,304 1999-01-13
US09/229,304 US6693081B2 (en) 1995-09-26 1999-01-13 Bone stimulating factor

Publications (1)

Publication Number Publication Date
CN1341120A true CN1341120A (zh) 2002-03-20

Family

ID=22860649

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00802780A Pending CN1341120A (zh) 1999-01-13 2000-01-13 骨刺激因子

Country Status (19)

Country Link
US (2) US6693081B2 (https=)
EP (1) EP1161450A1 (https=)
JP (1) JP2002538775A (https=)
KR (1) KR20010101425A (https=)
CN (1) CN1341120A (https=)
AU (1) AU779261B2 (https=)
BG (1) BG105682A (https=)
BR (1) BR0007816A (https=)
CA (1) CA2358908A1 (https=)
CZ (1) CZ20012456A3 (https=)
HU (1) HUP0105004A2 (https=)
IL (1) IL143990A0 (https=)
IS (1) IS5999A (https=)
MA (1) MA25594A1 (https=)
MX (1) MXPA01007043A (https=)
NO (1) NO20013257L (https=)
NZ (1) NZ512637A (https=)
PL (1) PL349786A1 (https=)
WO (1) WO2000042069A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159762A (zh) * 2013-03-25 2013-06-19 华东理工大学 表吲哚二酮衍生物及其用途

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6693081B2 (en) * 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor
WO2000075185A1 (en) * 1999-06-02 2000-12-14 Osteopharm Inc. Bone stimulating factor
CN100414265C (zh) * 2002-07-05 2008-08-27 加斯帕尔多塞米纳特里奇有限公司 用于定量输送颗粒状和粉末状材料、特别是用于分配所述材料的机器的体积计量装置
US7399826B1 (en) 2003-10-02 2008-07-15 Ali Sadat M Peptide for promoting healing of fractures
CA2838490A1 (en) * 2011-06-10 2012-12-13 Universite Libre De Bruxelles Targets and agents for the treatment of impaired bone fracture healing

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320118A (en) 1980-12-22 1982-03-16 Syntex (U.S.A.) Inc. Deca-, undeca-, dodeca- and tridecapeptides with thymic activity
US4897348A (en) 1983-08-25 1990-01-30 Sri International Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof
US4877864A (en) 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
US5011691A (en) 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
US5354557A (en) 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US4950483A (en) 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5024841A (en) 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US5264214A (en) 1988-11-21 1993-11-23 Collagen Corporation Composition for bone repair
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
FI903931A7 (fi) * 1988-12-08 1990-08-08 Sandoz Ag Neutrofiiliaktivoiva peptidi-2
US5461034A (en) 1989-02-23 1995-10-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenic growth polypeptides identified from regenerating bone marrow
EP0513201A1 (en) 1990-02-01 1992-11-19 University Of South Florida Leukocyte-derived growth factor
CA2040264A1 (en) 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists
AU668347B2 (en) 1990-11-21 1996-05-02 Torrey Pines Institute For Molecular Studies Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
JP3159705B2 (ja) * 1990-12-21 2001-04-23 キュラティブ テクノロジーズ，インコーポレーテッド 血管形成ペプチド
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
US5208219A (en) 1991-02-14 1993-05-04 Celtrix Pharmaceuticals Inc. Method for inducing bone growth
EP0499242B1 (en) 1991-02-15 1996-06-26 Takeda Chemical Industries, Ltd. Stimulation of endosteal bone formation with a cell growth factor
EP0504938A3 (en) 1991-03-22 1993-04-14 Suntory Limited Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
US5792664A (en) 1992-05-29 1998-08-11 The Rockefeller University Methods for producing and analyzing biopolymer ladders
JPH07509128A (ja) * 1992-07-13 1995-10-12 バイオネブラスカ・インコーポレーテッド 組換型ポリペプチドの修飾方法
US5304542A (en) 1992-08-28 1994-04-19 University Of Louisville Research Foundation, Inc. Use of platelet factor 4 to inhibit osteoblast proliferation
US5578569A (en) 1993-03-12 1996-11-26 Tam; Cherk S. Method of increasing bone growth
US5786327A (en) 1993-03-12 1998-07-28 Gensci Regeneration Sciences Inc. Bone stimulating factor, methods of isolating same, and methods of increasing bone growth comprising administering same
IL108947A0 (en) 1993-03-12 1994-06-24 Osteopharm Ltd Bone stimulating factor
US5661127A (en) 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US6352973B1 (en) 1995-06-07 2002-03-05 Osteopharm Inc. Bone stimulating factor
US5880094A (en) 1995-06-07 1999-03-09 Osteopharm Limited Polypeptides that stimulate bone growth
US6117839A (en) 1995-06-07 2000-09-12 Gensci Regeneration Sciences, Inc. Bone stimulating factor
ZA968062B (en) 1995-09-26 1997-06-18 Osteopharm Ltd Bone stimulating factor
US6693081B2 (en) * 1995-09-26 2004-02-17 Osteopharm Inc. Bone stimulating factor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159762A (zh) * 2013-03-25 2013-06-19 华东理工大学 表吲哚二酮衍生物及其用途
CN103159762B (zh) * 2013-03-25 2015-04-15 华东理工大学 表吲哚二酮衍生物及其用途

Also Published As

Publication number Publication date
BR0007816A (pt) 2002-12-31
US20040147450A1 (en) 2004-07-29
US20020090671A1 (en) 2002-07-11
IL143990A0 (en) 2002-04-21
NO20013257D0 (no) 2001-06-29
NO20013257L (no) 2001-08-17
AU3028200A (en) 2000-08-01
WO2000042069A1 (en) 2000-07-20
CA2358908A1 (en) 2000-07-20
EP1161450A1 (en) 2001-12-12
IS5999A (is) 2001-07-11
KR20010101425A (ko) 2001-11-14
NZ512637A (en) 2003-08-29
MA25594A1 (fr) 2002-12-31
MXPA01007043A (es) 2002-03-27
BG105682A (en) 2003-04-30
US6693081B2 (en) 2004-02-17
HUP0105004A2 (hu) 2002-04-29
AU779261B2 (en) 2005-01-13
PL349786A1 (en) 2002-09-09
CZ20012456A3 (cs) 2002-02-13
JP2002538775A (ja) 2002-11-19

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SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication