CN1325049C - 含有表没食子儿茶素没食子酸酯的组合物 - Google Patents

含有表没食子儿茶素没食子酸酯的组合物 Download PDF

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Publication number
CN1325049C
CN1325049C CNB028097823A CN02809782A CN1325049C CN 1325049 C CN1325049 C CN 1325049C CN B028097823 A CNB028097823 A CN B028097823A CN 02809782 A CN02809782 A CN 02809782A CN 1325049 C CN1325049 C CN 1325049C
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CN
China
Prior art keywords
compositions
polysaccharide
egcg
pectin
powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB028097823A
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English (en)
Chinese (zh)
Other versions
CN1509186A (zh
Inventor
C-C·彻恩
B·莱尤恩伯格
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DSM IP Assets BV
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DSM IP Assets BV
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Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of CN1509186A publication Critical patent/CN1509186A/zh
Application granted granted Critical
Publication of CN1325049C publication Critical patent/CN1325049C/zh
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Fertilizers (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CNB028097823A 2001-07-30 2002-07-22 含有表没食子儿茶素没食子酸酯的组合物 Expired - Fee Related CN1325049C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01118246 2001-07-30
EP01118246.6 2001-07-30

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA2007100964346A Division CN101028253A (zh) 2001-07-30 2002-07-22 含有表没食子儿茶素没食子酸酯的组合物

Publications (2)

Publication Number Publication Date
CN1509186A CN1509186A (zh) 2004-06-30
CN1325049C true CN1325049C (zh) 2007-07-11

Family

ID=8178165

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB028097823A Expired - Fee Related CN1325049C (zh) 2001-07-30 2002-07-22 含有表没食子儿茶素没食子酸酯的组合物
CNA2007100964346A Pending CN101028253A (zh) 2001-07-30 2002-07-22 含有表没食子儿茶素没食子酸酯的组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2007100964346A Pending CN101028253A (zh) 2001-07-30 2002-07-22 含有表没食子儿茶素没食子酸酯的组合物

Country Status (13)

Country Link
US (1) US20040198673A1 (enExample)
EP (1) EP1411986B1 (enExample)
JP (1) JP2005501833A (enExample)
KR (1) KR100611855B1 (enExample)
CN (2) CN1325049C (enExample)
AT (1) ATE388723T1 (enExample)
AU (1) AU2002327893B8 (enExample)
BR (1) BR0209864A (enExample)
CA (1) CA2450772C (enExample)
DE (1) DE60225560T2 (enExample)
ES (1) ES2301670T3 (enExample)
MX (1) MXPA04000618A (enExample)
WO (1) WO2003011339A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2351257T3 (es) 2005-02-15 2011-02-02 Dsm Ip Assets B.V. Composiciones que contienen polisacáridos.
CN100446762C (zh) * 2005-09-05 2008-12-31 中山大学 (-)-表没食子儿茶素没食子酸酯固体分散体及其制备方法与应用
KR20100075960A (ko) * 2007-10-29 2010-07-05 디에스엠 아이피 어셋츠 비.브이. 레스베라트롤 및 펙틴을 함유하는 조성물
ES2694426T3 (es) 2012-10-04 2018-12-20 Abbott Laboratories Procedimientos para mejorar el efecto de EGCg en la mitigación de la pérdida de músculo esquelético
WO2015136551A2 (en) * 2014-03-12 2015-09-17 Tata Chemicals Limited A molecular complex of epigallocatechin-3-gallate and a process for production thereof
CN104719910B (zh) * 2015-04-19 2017-07-28 福州乾正药业有限公司 具有热稳定性的egcg固体分散体组合物及其制备方法和应用
CN113384781B (zh) * 2020-03-11 2024-03-29 李彤 一种egcg雾化系统

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0573682A1 (en) * 1991-02-05 1993-12-15 Mitsui Norin Co., Ltd. Tea polyphenols as anti-hyperglycemic agents
JPH07223941A (ja) * 1994-02-14 1995-08-22 Nippon Ham Kk 抗補体作用物質
EP0742012A2 (en) * 1995-05-10 1996-11-13 Kureha Chemical Industry Co., Ltd. Pharmaceutical composition containing substance inhibiting HSP47 production
WO2000057875A1 (en) * 1999-03-30 2000-10-05 Purdue Research Foundation Compositions containing tea catechins as cancer specific proliferation inhibitors
WO2001049285A1 (en) * 2000-01-03 2001-07-12 Slk Foundation Flavonoid drug and dosage form, its production and use

Family Cites Families (29)

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US3666484A (en) * 1969-11-12 1972-05-30 Lipton Inc Thomas J Process for making a spray-dried instant tea of desired bulk density
US4268533A (en) * 1979-11-21 1981-05-19 General Foods Corporation Quick-set low methoxyl pectin composition
JPS5759803A (en) * 1980-09-30 1982-04-10 Takeda Chem Ind Ltd Granule of l-sodium ascorbate, its preparation, and tablet comprising it
AU587863B2 (en) * 1985-10-07 1989-08-31 Basf Aktiengesellschaft Vitamin-containing granules and production thereof
US4800096A (en) * 1987-05-29 1989-01-24 General Foods Corporation Pectin gelling composition
JP2812682B2 (ja) * 1988-05-24 1998-10-22 株式会社伊藤園 コレステロール排泄促進剤及びコレステロール排泄促進飲食物
DE3903217A1 (de) * 1989-02-03 1990-08-09 Boehringer Ingelheim Vetmed Verfahren zur herstellung fester pharmazeutischer zubereitungen
JPH03141220A (ja) * 1989-10-26 1991-06-17 Tsumura & Co 抗レトロウイルス剤
US4935256A (en) * 1989-10-31 1990-06-19 Procter & Gamble Company Process for making green tea solids
PT96229B (pt) * 1989-12-22 1998-06-30 Syntex Pharma Int Processo para a preparacao de composicoes farmaceuticas em po, secas por pulverizacao, directamente compressiveis em comprimidos, contendo naproxeno ou naproxeno sodico
JPH0595988A (ja) * 1990-10-22 1993-04-20 Kanebo Ltd 漢方エキス造粒物および漢方エキス含有固形製剤の製造方法
JP3469258B2 (ja) * 1992-10-09 2003-11-25 太陽化学株式会社 腎機能改善用剤
US5486507A (en) * 1994-01-14 1996-01-23 Fuisz Technologies Ltd. Porous particle aggregate and method therefor
JP4127864B2 (ja) * 1994-09-29 2008-07-30 太陽化学株式会社 グラム陰性菌増殖抑制剤
JPH08253423A (ja) * 1995-01-19 1996-10-01 Tokushu Meneki Kenkyusho:Kk ラクトフェリン含有食品・医薬品顆粒およびその製造 方法
US5997937A (en) * 1996-05-06 1999-12-07 Kraft Foods, Inc. Quick-setting gel mix
DE19627344A1 (de) * 1996-07-01 1998-01-08 Vitasyn Gmbh Entwicklung & Ver Therapeutisch wirksame bzw. gesundheitsfördernde Zubereitung aus definierten Polyphenolverbindungen
JP4098376B2 (ja) * 1996-09-05 2008-06-11 ビーエーエスエフ ソシエタス・ヨーロピア 錠剤特性の優れた水溶性ビタミン組成物およびその製造法
JP2001507701A (ja) * 1996-12-31 2001-06-12 インヘイル・セラピューティック・システムズ・インコーポレーテッド 親水性賦形剤を有する疎水性薬剤の溶液を噴霧乾燥するための方法及びその方法によって作製された組成物
JPH10279486A (ja) * 1997-04-02 1998-10-20 Taiyo Kagaku Co Ltd 免疫賦活組成物
JPH11116475A (ja) * 1997-10-07 1999-04-27 Snow Brand Milk Prod Co Ltd 炎症性腸疾患予防及び/又は治療剤
US5904924A (en) * 1997-11-04 1999-05-18 Oncologics, Inc. Green nutritional powder composition
US6093715A (en) * 1999-03-24 2000-07-25 Basf Aktiengesellschaft Process for producing riboflavin-containing granules
US6410052B1 (en) * 1999-03-30 2002-06-25 Purdue Research Foundation Tea catechins in sustained release formulations as cancer specific proliferation inhibitors
JP4082823B2 (ja) * 1999-05-06 2008-04-30 日本メナード化粧品株式会社 光毒性抑制剤
WO2001026691A1 (en) * 1999-10-12 2001-04-19 Suntory Limited Medicinal compositions for oral use
US20040202714A1 (en) * 1999-10-12 2004-10-14 Daiichi Suntory Pharma Co., Ltd. Oral pharmaceutical composition
JP3694733B2 (ja) * 2000-06-29 2005-09-14 独立行政法人農業・生物系特定産業技術研究機構 抗アレルギー剤
US6358526B1 (en) * 2000-08-16 2002-03-19 Rexall Sundown Method of making tablets and tablet compositions produced therefrom

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0573682A1 (en) * 1991-02-05 1993-12-15 Mitsui Norin Co., Ltd. Tea polyphenols as anti-hyperglycemic agents
JPH07223941A (ja) * 1994-02-14 1995-08-22 Nippon Ham Kk 抗補体作用物質
EP0742012A2 (en) * 1995-05-10 1996-11-13 Kureha Chemical Industry Co., Ltd. Pharmaceutical composition containing substance inhibiting HSP47 production
WO2000057875A1 (en) * 1999-03-30 2000-10-05 Purdue Research Foundation Compositions containing tea catechins as cancer specific proliferation inhibitors
WO2001049285A1 (en) * 2000-01-03 2001-07-12 Slk Foundation Flavonoid drug and dosage form, its production and use

Also Published As

Publication number Publication date
WO2003011339A1 (en) 2003-02-13
CA2450772A1 (en) 2003-02-13
JP2005501833A (ja) 2005-01-20
AU2002327893A1 (en) 2003-02-17
EP1411986B1 (en) 2008-03-12
MXPA04000618A (es) 2005-06-17
CN101028253A (zh) 2007-09-05
CN1509186A (zh) 2004-06-30
ATE388723T1 (de) 2008-03-15
KR20040032872A (ko) 2004-04-17
EP1411986A1 (en) 2004-04-28
BR0209864A (pt) 2004-06-08
DE60225560T2 (de) 2009-04-02
KR100611855B1 (ko) 2006-08-11
AU2002327893B8 (en) 2007-01-18
CA2450772C (en) 2008-09-30
AU2002327893B2 (en) 2006-12-21
US20040198673A1 (en) 2004-10-07
DE60225560D1 (de) 2008-04-24
ES2301670T3 (es) 2008-07-01

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Legal Events

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: DSMIP ASSET CO., LTD.

Free format text: FORMER OWNER: ROCHE VITAMINE S.A.

Effective date: 20041015

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20041015

Address after: Holland Heerlen

Applicant after: DSMIP N. V.

Address before: Basel

Applicant before: Roche Vitamin S.A.

C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20070711

Termination date: 20120722