CN1315806C - 取代的2-氨基-环烷烃甲酰胺和它们作为半胱氨酸蛋白酶抑制剂的用途 - Google Patents
取代的2-氨基-环烷烃甲酰胺和它们作为半胱氨酸蛋白酶抑制剂的用途 Download PDFInfo
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- CN1315806C CN1315806C CNB02824060XA CN02824060A CN1315806C CN 1315806 C CN1315806 C CN 1315806C CN B02824060X A CNB02824060X A CN B02824060XA CN 02824060 A CN02824060 A CN 02824060A CN 1315806 C CN1315806 C CN 1315806C
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- cyclohexyl
- indole
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- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Organic Chemistry (AREA)
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Molecular Biology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33675001P | 2001-12-04 | 2001-12-04 | |
| US60/336,750 | 2001-12-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1639119A CN1639119A (zh) | 2005-07-13 |
| CN1315806C true CN1315806C (zh) | 2007-05-16 |
Family
ID=23317485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB02824060XA Expired - Fee Related CN1315806C (zh) | 2001-12-04 | 2002-11-25 | 取代的2-氨基-环烷烃甲酰胺和它们作为半胱氨酸蛋白酶抑制剂的用途 |
Country Status (25)
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|---|---|
| US (1) | US6747053B2 (enExample) |
| EP (1) | EP1453801B1 (enExample) |
| JP (1) | JP2005517640A (enExample) |
| KR (1) | KR20050044660A (enExample) |
| CN (1) | CN1315806C (enExample) |
| AR (1) | AR037683A1 (enExample) |
| AT (1) | ATE357432T1 (enExample) |
| AU (1) | AU2002352126A1 (enExample) |
| BR (1) | BR0214642A (enExample) |
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| NO (1) | NO20042719L (enExample) |
| PA (1) | PA8559701A1 (enExample) |
| PE (1) | PE20030723A1 (enExample) |
| PL (1) | PL370766A1 (enExample) |
| RU (1) | RU2004120784A (enExample) |
| TW (1) | TW200303861A (enExample) |
| UY (1) | UY27561A1 (enExample) |
| WO (1) | WO2003048123A1 (enExample) |
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Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE494388T1 (de) * | 1999-01-13 | 2011-01-15 | Univ New York State Res Found | Neues verfahren zum erschaffen von proteinkinase- inhibitoren |
| US7005445B2 (en) * | 2001-10-22 | 2006-02-28 | The Research Foundation Of State University Of New York | Protein kinase and phosphatase inhibitors and methods for designing them |
| GB0128996D0 (en) | 2001-12-04 | 2002-01-23 | Novartis Ag | Organic compounds |
| ES2262996T3 (es) * | 2002-01-07 | 2006-12-01 | Eisai Co., Ltd. | Deazapurinas y sus usos. |
| SE0203712D0 (sv) | 2002-12-13 | 2002-12-13 | Astrazeneca Ab | Novel compounds |
| GB0403038D0 (en) | 2004-02-11 | 2004-03-17 | Novartis Ag | Organic compounds |
| WO2006007664A1 (en) * | 2004-07-22 | 2006-01-26 | Genomics Research Partners Pty Ltd | Agents and methods for diagnosing osteoarthritis |
| AU2006261954A1 (en) * | 2005-06-28 | 2007-01-04 | Merck & Co., Inc. | Non-nucleoside reverse transcriptase inhibitors |
| EP1749822B1 (en) * | 2005-08-05 | 2008-10-15 | Hybrigenics S.A. | Novel cysteine protease inhibitors and their therapeutic applications |
| CA2617725C (en) | 2005-08-05 | 2012-04-03 | Hybrigenics Sa | Novel cysteine protease inhibitors and their therapeutic applications |
| WO2007041775A1 (en) * | 2005-10-10 | 2007-04-19 | The University Of Queensland | Cysteine protease inhibitors incorporating azide groups |
| WO2007081530A2 (en) * | 2006-01-03 | 2007-07-19 | Med Institute, Inc. | Endoluminal medical device for local delivery of cathepsin inhibitors |
| JP4012239B2 (ja) * | 2006-01-11 | 2007-11-21 | 生化学工業株式会社 | オキサゾロン誘導体 |
| US7838542B2 (en) * | 2006-06-29 | 2010-11-23 | Kinex Pharmaceuticals, Llc | Bicyclic compositions and methods for modulating a kinase cascade |
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| BR112023003492A2 (pt) | 2020-08-26 | 2023-05-09 | Haisco Pharmaceuticals Pte Ltd | Composto de fórmula (i), composição farmacêutica e uso do composto |
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| WO2001047886A1 (en) * | 1999-12-24 | 2001-07-05 | F. Hoffmann-La Roche Ag | Nitrile derivatives as cathepsin k inhibitors |
| WO2001096285A1 (en) * | 2000-06-14 | 2001-12-20 | F. Hoffmann-La Roche Ag | Beta-amino acid nitrile derivatives |
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| HU177576B (en) | 1975-06-02 | 1981-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing 2-amino-cyclohexane carboxylic acid,its amides and similar compounds |
| DE4417163A1 (de) | 1994-05-17 | 1995-11-23 | Hoechst Schering Agrevo Gmbh | Heterocyclylamino- und Heterocyclyloxy-cycloalkyl-Derivate, ihre Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide |
| IT1283467B1 (it) | 1996-07-19 | 1998-04-21 | Menarini Farma Ind | Derivati di cicloalcani 1,2 sostituiti come inibitori della trombina, procedimento per la loro preparazione e loro impiego in formulazioni |
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| AU2002352663B2 (en) | 2001-11-13 | 2007-06-21 | Axys Pharmaceuticals, Inc. | Cyanoalkylamino derivatives as protease inhibitors |
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- 2002-11-25 AU AU2002352126A patent/AU2002352126A1/en not_active Abandoned
- 2002-11-25 HU HU0402344A patent/HUP0402344A2/hu unknown
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- 2002-11-25 KR KR1020047008481A patent/KR20050044660A/ko not_active Ceased
- 2002-11-25 MX MXPA04005263A patent/MXPA04005263A/es unknown
- 2002-11-25 CA CA002467435A patent/CA2467435A1/en not_active Abandoned
- 2002-11-25 JP JP2003549315A patent/JP2005517640A/ja active Pending
- 2002-11-25 DE DE60219068T patent/DE60219068T2/de not_active Expired - Fee Related
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001047886A1 (en) * | 1999-12-24 | 2001-07-05 | F. Hoffmann-La Roche Ag | Nitrile derivatives as cathepsin k inhibitors |
| WO2001096285A1 (en) * | 2000-06-14 | 2001-12-20 | F. Hoffmann-La Roche Ag | Beta-amino acid nitrile derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050044660A (ko) | 2005-05-12 |
| EP1453801B1 (en) | 2007-03-21 |
| TW200303861A (en) | 2003-09-16 |
| CN1639119A (zh) | 2005-07-13 |
| RU2004120784A (ru) | 2005-08-10 |
| US20030212097A1 (en) | 2003-11-13 |
| IL161992A0 (en) | 2005-11-20 |
| ES2282497T3 (es) | 2007-10-16 |
| GT200200253A (es) | 2003-07-03 |
| US6747053B2 (en) | 2004-06-08 |
| PA8559701A1 (es) | 2003-07-28 |
| DE60219068T2 (de) | 2007-12-13 |
| AU2002352126A1 (en) | 2003-06-17 |
| HUP0402344A2 (hu) | 2005-02-28 |
| ATE357432T1 (de) | 2007-04-15 |
| MXPA04005263A (es) | 2004-10-11 |
| JP2005517640A (ja) | 2005-06-16 |
| AR037683A1 (es) | 2004-12-01 |
| ZA200404343B (en) | 2006-07-26 |
| PL370766A1 (en) | 2005-05-30 |
| WO2003048123A1 (en) | 2003-06-12 |
| BR0214642A (pt) | 2004-11-03 |
| NO20042719L (no) | 2004-06-28 |
| EP1453801A1 (en) | 2004-09-08 |
| UY27561A1 (es) | 2003-06-30 |
| PE20030723A1 (es) | 2003-08-29 |
| DE60219068D1 (de) | 2007-05-03 |
| CA2467435A1 (en) | 2003-06-12 |
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