MXPA04005263A - 2-amino-cicloalcanocarboxamidas substituidas y su uso como inhibidores de cisteina proteasa. - Google Patents

2-amino-cicloalcanocarboxamidas substituidas y su uso como inhibidores de cisteina proteasa.

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Publication number
MXPA04005263A
MXPA04005263A MXPA04005263A MXPA04005263A MXPA04005263A MX PA04005263 A MXPA04005263 A MX PA04005263A MX PA04005263 A MXPA04005263 A MX PA04005263A MX PA04005263 A MXPA04005263 A MX PA04005263A MX PA04005263 A MXPA04005263 A MX PA04005263A
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Mexico
Prior art keywords
compounds
pharmaceutically acceptable
angina pectoris
cycloalkanecarboxamides
amino
Prior art date
Application number
MXPA04005263A
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English (en)
Inventor
Solang Palmer Wylie
Original Assignee
Hoffmann La Roche
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Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MXPA04005263A publication Critical patent/MXPA04005263A/es

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Abstract

La presente invencion se refiere a compuestos de formula(ver formula I)en donde R1, R2, R3, R4, R5, R6 y n son como se ha definido en la descripcion y las reivindicaciones y sales farmaceuticamente aceptables y/o esteres farmaceuticamente aceptables de los mismos. Los compuestos son utiles para el tratamiento de enfermedades que estan asociadas con cistein proteasas tales como osteoporosis, osteoartritis, artritis reumatoide, metastasis tumoral, glomerulonefritis, aterosclerosis, infarto de miocardio, angina de pecho, angina de pecho inestable, ataques al corazon, rotura de placa, ataques isquemicos transitorios, amaurosis fugax, enfermedad arterial oclusiva periferica, restenosis tras angioplastia y endoprotesis, formacion de aneurisma aortico abdominal, inflamacion, enfermedad autoinmune, malaria, citopatia tisular del fundus ocular y enfermedad respiratoria.
MXPA04005263A 2001-12-04 2002-11-25 2-amino-cicloalcanocarboxamidas substituidas y su uso como inhibidores de cisteina proteasa. MXPA04005263A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33675001P 2001-12-04 2001-12-04
PCT/EP2002/013221 WO2003048123A1 (en) 2001-12-04 2002-11-25 Substituted 2-amino-cycloalkanecarboxamides and their use as cysteine protease inhibitors

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MXPA04005263A true MXPA04005263A (es) 2004-10-11

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JP (1) JP2005517640A (es)
KR (1) KR20050044660A (es)
CN (1) CN1315806C (es)
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GT (1) GT200200253A (es)
HU (1) HUP0402344A2 (es)
IL (1) IL161992A0 (es)
MX (1) MXPA04005263A (es)
NO (1) NO20042719L (es)
PA (1) PA8559701A1 (es)
PE (1) PE20030723A1 (es)
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RU (1) RU2004120784A (es)
TW (1) TW200303861A (es)
UY (1) UY27561A1 (es)
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WO2000042213A1 (en) * 1999-01-13 2000-07-20 The Research Foundation Of State University Of New York A novel method for designing protein kinase inhibitors
US7005445B2 (en) * 2001-10-22 2006-02-28 The Research Foundation Of State University Of New York Protein kinase and phosphatase inhibitors and methods for designing them
GB0128996D0 (en) 2001-12-04 2002-01-23 Novartis Ag Organic compounds
DE60305446T4 (de) * 2002-01-07 2009-07-09 Eisai R&D Management Co., Ltd. Desazapurine und deren verwendung
SE0203712D0 (sv) 2002-12-13 2002-12-13 Astrazeneca Ab Novel compounds
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